Cancer vaccine triggers antiviral-type defences (original) (raw)

Immunotherapy

Nature volume 534, pages 329–331 (2016)Cite this article

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An immunotherapy approach targets nanoparticles to dendritic cells of the immune system, leading to an antitumour immune response with antiviral-like features. Initial clinical tests of this approach show promise. See Letter p.396

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Figure 1: An antitumour nanoparticle vaccine.

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References

  1. Kranz, L. M. et al. Nature 534, 396–401 (2016).
    Article ADS Google Scholar
  2. Joyce, J. A. & Fearon, D. T. Science 348, 74–80 (2015).
    Article CAS ADS Google Scholar
  3. Palucka, K. & Banchereau, J. Nature Rev. Cancer 12, 265–277 (2012).
    Article CAS Google Scholar
  4. Tel, J. et al. Cancer Res. 73, 1063–1075 (2013).
    Article CAS Google Scholar
  5. Tacken, P. J., de Vries, I. J., Torensma, R. & Figdor, C. G. Nature Rev. Immunol. 7, 790–802 (2007).
    Article CAS Google Scholar
  6. Bonifaz, L. C. et al. J. Exp. Med. 196, 1627–1638 (2002).
    Article CAS Google Scholar
  7. Bonifaz, L. C. et al. J. Exp. Med. 199, 815–824 (2004).
    Article CAS Google Scholar
  8. Tacken, P. J. et al. Blood 106, 1278–1285 (2005).
    Article CAS Google Scholar
  9. Cruz, L. J. et al. J. Control. Release 144, 118–126 (2010).
    Article CAS Google Scholar
  10. https://clinicaltrials.gov/ct2/results?term=dec-205&Search=Search
  11. Kuhn, A. N. et al. Gene Ther. 17, 961–971 (2010).
    Article CAS Google Scholar

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Authors and Affiliations

  1. Jolanda de Vries and Carl Figdor are in the Department of Tumor Immunology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands.,
    Jolanda De Vries & Carl Figdor

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  1. Jolanda De Vries
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  2. Carl Figdor
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Correspondence toJolanda De Vries or Carl Figdor.

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De Vries, J., Figdor, C. Cancer vaccine triggers antiviral-type defences.Nature 534, 329–331 (2016). https://doi.org/10.1038/nature18443

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