Sustained somatic gene inactivation by viral transfer of Cre recombinase (original) (raw)

References

  1. Sternberg, N., Hamilton, D., Austin, S., Yarmolinsky, M. and Hoess, R. 1981. Site-specific recombination and its role in the life cylce of bacteriophage P1. Cold Spring Harbor. Symp. 45: 297–309.
    Article CAS Google Scholar
  2. Sauer, B. 1993. Manipulation of transgenes by site-specific recombination: use of Cre recombinase. Methods Enzymol. 225: 890–900.
    Article CAS Google Scholar
  3. Orban, P.C., Chui, D. and Marth, J.D. 1992. Tissue- and site-specific DNA recombination in transgenic mice. Proc. Natl. Acad. Sci. USA 89: 6861–6865.
    Article CAS Google Scholar
  4. Lakso, M., Sauer, B., Mosinger, B. Jr., Lee, E.J., Manning, R.W., Yu, S.-H. et al. 1992. Targeted oncogene activation by site-specific recombination in transgenic mice. Proc. Natl. Acad. Sci. USA 89: 6232–6236.
    Article CAS Google Scholar
  5. Gu, H., Marth, J.D., Orban, P.C., Mossmann, H. and Rajewski, K. 1994. Deletion of the DNA polymerase ß gene in T cells using tissue-specific gene targeting. Science 265: 103–106.
    Article CAS Google Scholar
  6. Kühn, R., Schwenk, F., Aguet, M. and Rajewsky, K. 1995. Inducitale gene targeting in mice. Science 269: 1427–1429.
    Article Google Scholar
  7. Ramirez-Solis, R., Liu, P. and Bradley, A. 1995. Chromosome engineering in mice. Nature 378: 720–724.
    Article CAS Google Scholar
  8. Van Deursen, J., Fornerod, M., Van Rees, B. and Grosveld, G. 1995. Cre-mediated site-specific translocation between nonhomologous mouse chromosomes. Proc. Natl. Acad. Sci. USA 92: 7376–7380.
    Article CAS Google Scholar
  9. Copp, A.J. 1995. Death before birth: clues from gene knockouts and mutations. TIG 11: 87–93.
    Article CAS Google Scholar
  10. Krieger, M. and Herz, J. 1994. Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). Ann. Rev. Biochem. 63: 601–637.
    Article CAS Google Scholar
  11. Herz, J., Clouthier, D.E. and Hammer, R.E. 1992. LDL receptor-related protein internalizes and degrades uPA/PAI-1 complexes and is essential for embryo implantation. Cell 71: 411–421.
    Article CAS Google Scholar
  12. Anton, M. and Graham, F.L. 1995. Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression. J. Virol. 69: 4600–4606.
    CAS PubMed PubMed Central Google Scholar
  13. Pereira, D.S., Rosenthal, K.L. and Graham, F.L. 1995. Identification of adenovirus E1A regions which affect MHC class I expression and susceptibility to cytotoxic T lymphocytes. Virol. 211: 268–277.
    Article CAS Google Scholar
  14. Yang, Y. and Wilson, J.M. 1995. Clearance of adenovirus-infected hepatocytes by MHC class l-restricted CD4+ CTLs in vivo. J. Immunol. 155: 2564–2570.
    CAS PubMed Google Scholar
  15. Yang, Y., Nunes, F.A., Berencsi, K., Furth, E.E., Gonczol, E., and Wilson, J.M. 1994. Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc. Natl. Acad. Sci. USA 91: 4407–4411.
    Article CAS Google Scholar
  16. Stratford-Perricaudet, L.D., Makeh, I., Perricaudet, M. and Briand, P. 1992. Widespread long-term gene transfer to mouse skeletal muscle and heart. J. Clin. Invest. 90: 626–630.
    Article CAS Google Scholar
  17. Herz, J. and Gerard, R.D. 1993. Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc. Natl. Acad. Sci. USA 90: 2812–2816.
    Article CAS Google Scholar
  18. Soriano, P., Montgomery, C., Geske, R. and Bradley, A. 1991. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell 64: 693–702.
    Article CAS Google Scholar
  19. Strickland, D.K., Ashcom, J.D., Williams, S., Burgess, W.H., Migliorini, M. and Argraves, W.S. 1990. Sequence identity between the α2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multifunctional receptor. J. Biol. Chem. 265: 17401–17404.
    CAS PubMed Google Scholar
  20. Kristensen, T., Moestrup, S.K., Gliemann, J., Bendtsen, L., Sand, O. and Sottrup-Jensen, L. 1990. Evidence that the newly cloned low-density-lipoprotein receptor related protein (LRP) is the α2-macroglobulin receptor. FEBS Lett. 276: 151–155.
    Article CAS Google Scholar
  21. Wang, Y., Krushel, L.A. and Edelman, G.M. 1996. Targeted DNA recombination in vivo using an adenovirus carrying the ere recombinase. Proc. Natl. Acad. Sci. USA 93: 3932–3936.
    Article CAS Google Scholar
  22. Kütt, H., Herz, J. and Stanley, K.K. 1989. Structure of the low-density lipoprotein receptor-related protein (LRP) promoter. Biochim. Biophys. Acta 1009: 229–236.
    Article Google Scholar
  23. Willnow, T.E. and Herz, J. 1994. Homologous recombination for gene replacement in mouse cell lines, pp. 305–334 in Methods in cell biology 43. Roth, M. (ed.). Academic Press, San Diego.
    Google Scholar
  24. Willnow, T.E., Armstrong, S.A., Hammer, R.E. and Herz, J. 1995. Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo. Proc. Natl. Acad. Sci. USA 92: 4537–4541.
    Article CAS Google Scholar
  25. Willnow, T.E., Sheng, Z., Ishibashi, S. and Herz, J. 1994. Inhibition of hepatic chylomicron remnant uptake by gene transfer of a receptor antagonist. Science 264: 1471–1474
    Article CAS Google Scholar

Download references