Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity (original) (raw)
Thery, C., Zitvogel, L. & Amigorena, S. Exosomes: composition, biogenesis and function. Nature Rev. Immunol.2, 569–579 (2002). ArticleCAS Google Scholar
Skog, J. et al. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nature Cell Biol.10, 1470–1476 (2008). ArticleCAS Google Scholar
Islam, A. et al. The brefeldin A-inhibited guanine nucleotide-exchange protein, BIG2, regulates the constitutive release of TNFR1 exosome-like vesicles. J. Biol. Chem.282, 9591–9599 (2007). ArticleCAS Google Scholar
El-Shami, M. et al. Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components. Genes Dev.21, 2539–2544 (2007). ArticleCAS Google Scholar
Yu, J. H., Yang, W. H., Gulick, T., Bloch, K. D. & Bloch, D. B. Ge-1 is a central component of the mammalian cytoplasmic mRNA processing body. RNA11, 1795–1802 (2005). ArticleCAS Google Scholar
Valadi, H. et al. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nature Cell Biol.9, 654–659 (2007). ArticleCAS Google Scholar
Taylor, D. D. & Gercel-Taylor, C. MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol. Oncol.110, 13–21 (2008). ArticleCAS Google Scholar
Augustin, R., Riley, J. & Moley, K. H. GLUT8 contains a [DE]XXXL[LI] sorting motif and localizes to a late endosomal/lysosomal compartment. Traffic6, 1196–1212 (2005). ArticleCAS Google Scholar
Sherer, N. M. et al. Visualization of retroviral replication in living cells reveals budding into multivesicular bodies. Traffic4, 785–801 (2003). ArticleCAS Google Scholar
Laurino, C. C. et al. Human autoantibodies to diacyl-phosphatidylethanolamine recognize a specific set of discrete cytoplasmic domains. Clin. Exp. Immunol.143, 572–584 (2006). ArticleCAS Google Scholar
Kedersha, N. et al. Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J. Cell Biol.169, 871–884 (2005). ArticleCAS Google Scholar
Vasudevan, S. & Steitz, J. A. AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Cell128, 1105–1118 (2007). ArticleCAS Google Scholar
Bloch, D. B., Gulick, T., Bloch, K. D. & Yang, W. H. Processing body autoantibodies reconsidered. RNA12, 707–709 (2006). ArticleCAS Google Scholar
Lykke-Andersen, J. & Wagner, E. Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. Genes Dev.19, 351–361 (2005). ArticleCAS Google Scholar
Escola, J. M. et al. Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J. Biol. Chem.273, 20121–20127 (1998). ArticleCAS Google Scholar
Doench, J. G. & Sharp, P. A. Specificity of microRNA target selection in translational repression. Genes Dev.18, 504–511 (2004). ArticleCAS Google Scholar
Farh, K. K. et al. The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science310, 1817–1821 (2005). ArticleCAS Google Scholar
Matsumoto, M. et al. Large-scale analysis of the human ubiquitin-related proteome. Proteomics5, 4145–4151 (2005). ArticleCAS Google Scholar
Hock, J. et al. Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells. EMBO Rep.8, 1052–1060 (2007). Article Google Scholar
Razi, M. & Futter, C. E. Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation. Mol. Biol. Cell17, 3469–3483 (2006). ArticleCAS Google Scholar
Cabezas, A., Bache, K. G., Brech, A. & Stenmark, H. Alix regulates cortical actin and the spatial distribution of endosomes. J. Cell Sci.118, 2625–2635 (2005). ArticleCAS Google Scholar
Liu, J. et al. A role for the P-body component GW182 in microRNA function. Nature Cell Biol.7, 1261–1266 (2005). Article Google Scholar
Doyotte, A., Mironov, A., McKenzie, E. & Woodman, P. The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis. Proc. Natl Acad. Sci. USA105, 6308–6313 (2008). ArticleCAS Google Scholar
Adams, B. D., Furneaux, H. & White, B. A. The micro-ribonucleic acid (miRNA) miR-206 targets the human estrogen receptor-alpha (ERα) and represses ERα messenger RNA and protein expression in breast cancer cell lines. Mol. Endocrinol.21, 1132–1147 (2007). ArticleCAS Google Scholar
Buchet-Poyau, K. et al. Identification and characterization of human Mex.-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies. Nucleic Acids Res.35, 1289–1300 (2007). ArticleCAS Google Scholar
Vasudevan, S., Tong, Y. & Steitz, J. A. Cell-cycle control of microRNA-mediated translation regulation. Cell Cycle7, 1545–1549 (2008). ArticleCAS Google Scholar
Sen, G. L. & Blau, H. M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nature Cell Biol.7, 633–636 (2005). ArticleCAS Google Scholar
Lee, S. L. et al. Silencing by small RNAs is linked to endosomal trafficking. Nature Cell Biol.11, 10.138/ncb1930 (2009). ArticleCAS Google Scholar
Li, S. et al. Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing. J. Cell Sci.121, 4134–4144 (2008). ArticleCAS Google Scholar
Till, S. et al. A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain. Nature Struct. Mol. Biol.14, 897–903 (2007). ArticleCAS Google Scholar
Eulalio, A., Huntzinger, E. & Izaurralde, E. GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nature Struct. Mol. Biol.15, 346–353 (2008). ArticleCAS Google Scholar
Eulalio, A. et al. Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. Genes Dev.21, 2558–2570 (2007). ArticleCAS Google Scholar
Chu, C. Y. & Rana, T. M. Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol.4, e210 (2006). Article Google Scholar
Schwamborn, J. C., Berezikov, E. & Knoblich, J. A. The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell136, 913–925 (2009). ArticleCAS Google Scholar
Hammell, C. M., Lubin, I., Boag, P. R., Blackwell, T. K. & Ambros, V. nhl-2 Modulates microRNA activity in Caenorhabditis elegans. Cell136, 926–938 (2009). ArticleCAS Google Scholar
Raposo, G. et al. B lymphocytes secrete antigen-presenting vesicles. J. Exp. Med.183, 1161–1172 (1996). ArticleCAS Google Scholar
Vidal, M., Mangeat, P. & Hoekstra, D. Aggregation reroutes molecules from a recycling to a vesicle-mediated secretion pathway during reticulocyte maturation. J. Cell Sci.110 (Pt 16), 1867–1877 (1997). CASPubMed Google Scholar
Jakymiw, A. et al. Disruption of GW bodies impairs mammalian RNA interference. Nature Cell Biol.7, 1267–1274 (2005). Article Google Scholar
Kedersha, N. & Anderson, P. Mammalian stress granules and processing bodies. Methods Enzymol.431, 61–81 (2007). ArticleCAS Google Scholar
Srivastava, S. P., Kumar, K. U. & Kaufman, R. J. Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase. J. Biol. Chem.273, 2416–2423 (1998). ArticleCAS Google Scholar
Pfeffer, S., Lagos-Quintana, M. & Tuschl, T. Cloning of small RNA molecules. Curr. Protoc. Mol. Biol. ch 26, Unit 26.4 (2005).
Zhou, F. C. et al. Efficient infection by a recombinant Kaposi's sarcoma-associated herpesvirus cloned in a bacterial artificial chromosome: application for genetic analysis. J. Virol.76, 6185–6196 (2002). ArticleCAS Google Scholar
Eisenberg, E. & Levanon, E. Y. Human housekeeping genes are compact. Trends Genet.19, 362–365 (2003). ArticleCAS Google Scholar