SAP couples Fyn to SLAM immune receptors (original) (raw)
Sayos, J. et al. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM. Nature395, 462–469 (1998). ArticleCAS Google Scholar
Coffey, A.J. et al. Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene. Nature Genet.20, 129–135 (1998). ArticleCAS Google Scholar
Nichols, K.E. et al. Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome. Proc. Natl Acad. Sci. USA95, 13765–13770 (1998). ArticleCAS Google Scholar
Poy, F. et al. Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition. Mol. Cell4, 555–561 (1999). ArticleCAS Google Scholar
Latour, S. et al. Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product. Nature Immunol.2, 681–690 (2001). ArticleCAS Google Scholar
Morra, M. et al. X-linked lymphoproliferative disease: a progressive immunodeficiency. Annu. Rev. Immunol.19, 657–682 (2001). ArticleCAS Google Scholar
Sidorenko, S.P. & Clark, E.A. Characterization of a cell surface glycoprotein IPO-3, expressed on activated human B and T lymphocytes. J. Immunol.151, 4614–4624 (1993). CASPubMed Google Scholar
Wang, N. et al. CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells. Immunogenetics53, 382–394 (2001). ArticleCAS Google Scholar
Cocks, B.G. et al. A novel receptor involved in T-cell activation. Nature376, 260–263 (1995). ArticleCAS Google Scholar
Punnonen, J. et al. Soluble and membrane-bound forms of signaling lymphocytic activation molecule (SLAM) induce proliferation and Ig synthesis by activated human B lymphocytes. J. Exp. Med.185, 993–1004 (1997). ArticleCAS Google Scholar
Mavaddat, N. et al. Signaling lymphocytic activation molecule (CDw150) is homophilic but self-associates with very low affinity. J. Biol. Chem.275, 28100–28109 (2000). CASPubMed Google Scholar
Tatsuo, H., Ono, N., Tanaka, K. & Yanagi, Y. SLAM (CDw150) is a cellular receptor for measles virus. Nature406, 893–897 (2000). ArticleCAS Google Scholar
Wu, C. et al. SAP controls T cell responses to virus and terminal differentiation of TH2 cells. Nature Immunol.2, 410–414 (2001). ArticleCAS Google Scholar
Czar, M.J. et al. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP. Proc. Natl Acad. Sci. USA98, 7449–7454 (2001). ArticleCAS Google Scholar
Sayos, J. et al. Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4. Int. Immunol.12, 1749–1757 (2000). ArticleCAS Google Scholar
Sayos, J. et al. Cell surface receptors Ly-9 and CD84 recruit the X-linked lymphoproliferative disease gene product SAP. Blood97, 3867–3874 (2001). ArticleCAS Google Scholar
Morra, M. et al. Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells. EMBO J.20, 5840–5852 (2001). ArticleCAS Google Scholar
Morra, M. et al. Characterization of SH2D1A missense mutations identified in X-linked lymphoproliferative disease patients. J. Biol. Chem.276, 36809–36816 (2001). ArticleCAS Google Scholar
Noble, M., E. M., Musacchio, A., Saraster, M., Courtneidge, S.A. & Wierenga, R.K. Crystal structure of the SH3 domain in human Fyn; comparison of the three-dimensional structure of SH3 domains in tyrosine kinases and spectrin. EMBO J.12, 2617–2624 (1993). ArticleCAS Google Scholar
Moarefi, I. et al. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement. Nature385, 650–653 (1997). ArticleCAS Google Scholar
Holdorf, A.D., Lee, K.H., Burack, W.R., Allen, P.M. & Shaw, A.S. Regulation of Lck activity by CD4 and CD28 in the immunological synapse. Nature Immunol.3, 259–264 (2002). ArticleCAS Google Scholar
Xu, W., Harrison, S.C. & Eck, M.J. Three-dimensional structure of the tyrosine kinase c-Src. Nature385, 595–602 (1997). ArticleCAS Google Scholar
Hof, P., Pluskey, S., Dhe-Paganon, S., Eck, M.J. & Shoelson, S.E. Crystal structure of the tyrosine phosphatase SHP-2. Cell92, 441–450 (1998). ArticleCAS Google Scholar
Howie, D. et al. Antibodies directed at murine CD150(SLAM) mediate cell co-stimulation in both a SAP-dependent and SAP-independent fashion. Blood (in the press).
Howie, D. et al. Molecular dissection of the signaling and costimulatory functions of CD150 (SLAM): CD150/SAP binding and CD150-mediated costimulation. Blood99, 957–965 (2002). ArticleCAS Google Scholar
Nagy, N. et al. SH2D1A and SLAM protein expression in human lymphocytes and derived cell lines. Int. J. Cancer88, 439–447 (2000). ArticleCAS Google Scholar
Navaza, J. Implementation of molecular replacement in AMoRe. Acta Crystallogr. D Biol. Crystallogr.57, 1367–1372 (2001). ArticleCAS Google Scholar
Jones, T.A. & Kjeldgaard, M. Electron-density map interpretation. Methods Enzymol.277, 173–208 (1997). ArticleCAS Google Scholar
Brunger, A.T. et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. Acta Crystallogr. D. Biol. Crystallogr.54, 905–921 (1998). ArticleCAS Google Scholar
Nagy, N. et al. The X-linked lymphoproliferative disease gene product SAP is expressed in activated T and NK cells. Immunol. Lett.82, 141–147 (2002). ArticleCAS Google Scholar