Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus (original) (raw)

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In the version of this article initially published, there were two errors in the author affiliations and corresponding author details. Jian-Jun Liu is also affiliated with footnote 17, and Sen Yang and Xue-Jun Zhang are the corresponding authors. These errors have been corrected in the HTML and PDF versions of the article.

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Acknowledgements

We thank all study participants. This study was funded by the National Natural Science Foundation (30972727), the Key Project of National Natural Science Foundation (30530670 and 30830089), the Anhui Provincial Special Scientific Program (2007-7) and the Anhui Skin Genetic Study Innovative Research Team Program (TD200701).

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Author notes

  1. Jian-Wen Han, Hou-Feng Zheng and Yong Cui: These authors contributed equally to this work.

Authors and Affiliations

  1. Institute of Dermatology and Department of Dermatology at NO. 1 Hospital, Anhui Medical University, Hefei, Anhui, China
    Jian-Wen Han, Hou-Feng Zheng, Yong Cui, Liang-Dan Sun, Dong-Qing Ye, Zhi Hu, Xian-Bo Zuo, Fu-Sheng Zhou, Wen-Hui Du, Yi-Lin Cheng, Jian-Qiang Yang, Song-Ke Shen, Jian Li, Yu-Jun Sheng, Min Gao, Feng-Li Xiao, Cheng Quan, Chi Zhang, Zheng Zhang, Kun-Ju Zhu, Yang Li, Da-Yan Hu, Wen-Sheng Lu, Sheng-Xiu Liu, Hui Li, Yun-Qing Ren, Zai-Xing Wang, Chun-Jun Yang, Pei-Guang Wang, Wen-Ming Zhou, Yong-Mei Lv, An-Ping Zhang, Sheng-Quan Zhang, Da Lin, Feng-Yu Zhang, Sen Yang, Jian-Jun Liu & Xue-Jun Zhang
  2. Key Laboratory of Dermatology, Anhui Medical University, Ministry of Education, China, Hefei, Anhui, China.,
    Jian-Wen Han, Hou-Feng Zheng, Yong Cui, Liang-Dan Sun, Dong-Qing Ye, Zhi Hu, Xian-Bo Zuo, Fu-Sheng Zhou, Wen-Hui Du, Yi-Lin Cheng, Jian-Qiang Yang, Song-Ke Shen, Jian Li, Yu-Jun Sheng, Min Gao, Feng-Li Xiao, Cheng Quan, Chi Zhang, Zheng Zhang, Kun-Ju Zhu, Yang Li, Da-Yan Hu, Wen-Sheng Lu, Sheng-Xiu Liu, Hui Li, Yun-Qing Ren, Zai-Xing Wang, Chun-Jun Yang, Pei-Guang Wang, Wen-Ming Zhou, Yong-Mei Lv, An-Ping Zhang, Sheng-Quan Zhang, Da Lin, Feng-Yu Zhang, Sen Yang, Jian-Jun Liu & Xue-Jun Zhang
  3. Department of Dermatology, Huashan Hospital of Fudan University, Shanghai, China
    Jin-Hua Xu & Xue-Jun Zhang
  4. Department of Rheumatology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China
    Zhi-Ming Cai & Qing-Wen Wang
  5. Chinese National Human Genome Center at Shanghai, Shanghai, China
    Wei Huang, Guo-Ping Zhao, Min Shen & Ying Wang
  6. Department of Dermatology, Xiangya Hospital, Central South University, Changsha, Hunan, China
    Hong-Fu Xie & Xiao-Xia Zuo
  7. Department of Dermatology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
    Hong Fang & Wei-Fang Zhu
  8. Department of Dermatology, Epigenetic Research Center, Second Xiangya Hospital, Central South University, Changsha, Hunan, China
    Qian-Jin Lu & Fei Gao
  9. Department of Rheumatology at NO. 1 Hospital, Anhui Medical University, Hefei, Anhui, China
    Jian-Hua Xu
  10. Department of Rheumatology, Affiliated Provincial Hospital of Anhui Medical University, Hefei, Anhui, China
    Xiang-Pei Li
  11. Department of Rheumatology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
    Yun-Feng Pan & Jian-Lin Huang
  12. Department of Dermatology, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China
    Dan-Qi Deng & Pei-Lian Zhang
  13. Department of Dermatology, The Second Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
    Fan-Qin Zeng & Qing Guo
  14. Department of Rheumatology, Shenzhen Fourth People's Hospital, Shenzhen, Guangdong, China
    Zhi-Zhong Ye & Bo Li
  15. Department of Dermatology, China-Japan Friendship Hospital, Beijing, China
    Xiao-Yan Zhang & Li Ma
  16. Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, China
    Fei Hao & Zhi-Fang Zhai
  17. Human Genetics, Genome Institute of Singapore, Singapore, Singapore
    Yi Li, Hui Qi Low & Jian-Jun Liu

Authors

  1. Jian-Wen Han
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  2. Hou-Feng Zheng
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  3. Yong Cui
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  4. Liang-Dan Sun
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  5. Dong-Qing Ye
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  6. Zhi Hu
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  7. Jin-Hua Xu
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  8. Zhi-Ming Cai
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  9. Wei Huang
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  10. Guo-Ping Zhao
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  11. Hong-Fu Xie
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  12. Hong Fang
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  13. Qian-Jin Lu
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  14. Jian-Hua Xu
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  15. Xiang-Pei Li
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  16. Yun-Feng Pan
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  17. Dan-Qi Deng
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  18. Fan-Qin Zeng
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  19. Zhi-Zhong Ye
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  20. Xiao-Yan Zhang
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  21. Qing-Wen Wang
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  22. Fei Hao
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  23. Li Ma
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  24. Xian-Bo Zuo
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  25. Fu-Sheng Zhou
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  26. Wen-Hui Du
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  27. Yi-Lin Cheng
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  28. Jian-Qiang Yang
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  29. Song-Ke Shen
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  30. Jian Li
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  31. Yu-Jun Sheng
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  32. Xiao-Xia Zuo
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  33. Wei-Fang Zhu
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  34. Fei Gao
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  35. Pei-Lian Zhang
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  36. Qing Guo
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  37. Bo Li
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  38. Min Gao
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  39. Feng-Li Xiao
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  40. Cheng Quan
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  41. Chi Zhang
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  42. Zheng Zhang
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  43. Kun-Ju Zhu
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  44. Yang Li
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  45. Da-Yan Hu
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  46. Wen-Sheng Lu
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  47. Jian-Lin Huang
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  48. Sheng-Xiu Liu
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  49. Hui Li
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  50. Yun-Qing Ren
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  51. Zai-Xing Wang
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  52. Chun-Jun Yang
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  53. Pei-Guang Wang
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  54. Wen-Ming Zhou
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  55. Yong-Mei Lv
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  56. An-Ping Zhang
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  57. Sheng-Quan Zhang
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  58. Da Lin
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  59. Yi Li
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  60. Hui Qi Low
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  61. Min Shen
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  62. Zhi-Fang Zhai
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  63. Ying Wang
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  64. Feng-Yu Zhang
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  65. Sen Yang
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  66. Jian-Jun Liu
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  67. Xue-Jun Zhang
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Contributions

X.-J.Z. conceived of this study and obtained financial support. X.-J.Z., J.-J.L. and S.Y. designed the study. J.-W.H., H.-F.Z., Y.C. and L.-D.S. participated in the design and were responsible for sample selection, genotyping and project management. D.-Q.Y., Z.H., Jin-Hua Xu, Z.-M.C., H.-F.X., H.F., Q.-J.L., Jian-Hua Xu, X.-P.L., Y.-F.P., D.-Q.D., F.-Q.Z., Z.-Z.Y., X.-Y.Z., Q.-W.W., F.H., L.M., X.-X.Z., W.-F.Z., F.G., P.-L.Z., Q.G., B.L., M.G., F.-L.X., J.-L.H., S.-X.L., H.L., Z.-X.W., C.-J.Y., P.-G.W., W.-M.Z., A.-P.Z., D.L. and Z.-F.Z. conducted sample selection and data management. W.-H.D., J.-Q.Y., S.-K.S., J.L., Y.-J.S., K.-J.Z., Yang Li, D.-Y.H. and Y.-M.L. undertook recruitment, collected phenotype data, undertook related data handling and calculation, managed recruitment and obtained biological samples. W.H., G.-P.Z., F.-S.Z., Y.-L.C., C.Q., C.Z., Z.Z., W.-S.L., Y.-Q.R., S.-Q.Z., M.S. and Y.W. performed genotyping analysis. H.-F.Z., X.-B.Z., Yi Li, H.Q.L. and F.-Y.Z. undertook data processing, statistical analysis and bioinformatics investigations. All the authors contributed to the final paper, with X.-J.Z., J.-J.L., S.Y., J.-W.H., H.-F.Z., Y.C. and L.-D.S playing key roles.

Corresponding authors

Correspondence toSen Yang or Xue-Jun Zhang.

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Han, JW., Zheng, HF., Cui, Y. et al. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus.Nat Genet 41, 1234–1237 (2009). https://doi.org/10.1038/ng.472

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