Genetics of reproductive lifespan (original) (raw)

• News & Views
• Published: June 2009

Nature Genetics volume 41, pages 637–638 (2009)Cite this article

• 1482 Accesses
• 77 Citations
• Metrics details

Five genome-wide association studies of the timing of menarche and menopause have now taken us beyond the range of candidate gene and linkage studies. The list of new genetic associations identified for these two traits should shed light on the mechanisms of ovarian aging, as well as breast cancer and other diseases associated with reproductive lifespan.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

• Complex genetics of female fertility

  • Rahul Gajbhiye
  • , Jenny N. Fung
  • & Grant W. Montgomery
    npj Genomic Medicine Open Access 12 October 2018

• Metabolic characterization of menopause: cross-sectional and longitudinal evidence

  • Qin Wang
  • , Diana L. Santos Ferreira
  • … Debbie A. Lawlor
    BMC Medicine Open Access 06 February 2018

• Current understanding of ovarian aging

  • Qian Li
  • , XiaoDan Geng
  • … QingHua Shi
    Science China Life Sciences Open Access 30 August 2012

Access options

Subscribe to this journal

Receive 12 print issues and online access

$259.00 per year

only $21.58 per issue

Buy this article

• Purchase on SpringerLink
• Instant access to the full article PDF.

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Additional access options:

• Log in
• Learn about institutional subscriptions
• Read our FAQs
• Contact customer support

Figure 1: Potential health impacts of ovarian aging.

References

1. Chumlea, W.C. et al. Pediatrics 111, 110–113 (2003).
   Article Google Scholar
2. Euling, S.Y. et al. Pediatrics 121, S172–S191 (2008).
   Article Google Scholar
3. Parent, A.S. et al. Endocr. Rev. 24, 668–693 (2003).
   Article Google Scholar
4. Remsberg, K.E. et al. J. Clin. Endocrinol. Metab. 90, 2718–2724 (2005).
   Article CAS Google Scholar
5. Sowers, M.R. in Women and Health (eds. Goldman, M.B. & Hatch, M.C.) 1155–1168 (2000).
   Book Google Scholar
6. Van Asselt, K.M. Am. J. Hum. Genet. 74, 444–453 (2004).
   Article CAS Google Scholar
7. He, C. et al. Nat. Genet. 41, 724–728, (2009).
   Article CAS Google Scholar
8. Ong, K.K. et al. Nat. Genet. 41, 729–733 (2009).
   Article CAS Google Scholar
9. Perry, J.R.B. et al. Nat. Genet. 41, 648–650, (2009).
   Article CAS Google Scholar
10. Sulem, P. et al. Nat. Genet. 41, 734–738 (2009).
    Article CAS Google Scholar
11. Stolk, L. et al. Nat. Genet. 41, 645–647, (2009).
    Article CAS Google Scholar
12. Sovio, U. et al. PLoS Genet. 5, e1000409 (2009).
    Article Google Scholar
13. Reeves, G.K. et al. Br. J. Cancer 100, 538–544 (2009).
    Article CAS Google Scholar

Download references

Author information

Authors and Affiliations

1. Patricia Hartge is at the Division of Cancer Epidemiology and Genetics, in the National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. hartgep@mail.nih.gov,
   Patricia Hartge

Rights and permissions

About this article

Cite this article

Hartge, P. Genetics of reproductive lifespan.Nat Genet 41, 637–638 (2009). https://doi.org/10.1038/ng0609-637

Download citation

• Issue date: June 2009
• DOI: https://doi.org/10.1038/ng0609-637

This article is cited by