RIGging an antiviral defense—it's in the CARDs (original) (raw)

Nature Immunology volume 5, pages 699–701 (2004)Cite this article

How do cells fend off intracellular viruses that slip in below extracellular defensive 'radar screens'? The identification of a cytoplasmic RNA helicase that signals through CARD interactions links viral detection to the interferon-β induction pathway.

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Figure 1: Signaling pathways leading to IFN-β induction.

K.R.

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Authors and Affiliations

  1. Departments of Pathology and Microbiology,
    David E Levy & Isabelle J Marié
  2. Department of Pathology, New York University School of Medicine, New York, 10016, New York, USA
    David E Levy & Isabelle J Marié

Authors

  1. David E Levy
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  2. Isabelle J Marié
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Levy, D., Marié, I. RIGging an antiviral defense—it's in the CARDs.Nat Immunol 5, 699–701 (2004). https://doi.org/10.1038/ni0704-699

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