COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor–induced entry into the cell cycle from quiescence (original) (raw)
Dong, C., Davis, R.J. & Flavell, R.A. MAP kinases in immune response. Annu. Rev. Immunol.20, 55–72 (2002). ArticleCASPubMed Google Scholar
Ruland, J. & Mak, T.W. From antigen to activation: specific signal transduction pathways linking antigen receptors to NFκB. Semin. Immunol.15, 177–183 (2003). ArticleCASPubMed Google Scholar
Rowell, E.A. & Wells, A.D. The role of cyclin-dependent kinases in T-cell development, proliferation and function. Crit. Rev. Immunol.26, 189–212 (2006). ArticleCASPubMed Google Scholar
Sage, J., Miller, A.L., Perez-Mancera, P.A., Wysocki, J.M. & Jacks, T. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry. Nature424, 223–228 (2003). ArticleCASPubMed Google Scholar
Ren, S. & Rollins, B.J. Cyclin C/cdk3 promotes Rb-dependent G0 exit. Cell117, 239–251 (2004). ArticleCASPubMed Google Scholar
Boylan, J.F., Sharp, D.M., Leffet, L., Bowers, A. & Pan, W. Analysis of site-specific phosphorylation of the retinoblastoma protein during cell cycle progression. Exp. Cell Res.248, 110–114 (1999). ArticleCASPubMed Google Scholar
Sherr, C.J. & Roberts, J.M. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev.13, 1501–1512 (1999). ArticleCASPubMed Google Scholar
Grumont, R. et al. The mitogen-induced increase in T cell size involves PKC and NFAT activation of Rel/NF-κB-dependent c-Myc expression. Immunity21, 19–30 (2004). ArticleCASPubMed Google Scholar
Liu, Y.C. Ubiquitin ligases and the immune response. Annu. Rev. Immunol.22, 81–127 (2004). ArticlePubMed Google Scholar
Bech-Otschir, D., Seeger, M. & Dubiel, W. The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis. J. Cell Sci.115, 467–473 (2002). CASPubMed Google Scholar
Zhou, C. et al. Fission yeast COP9/Signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p. Mol. Cell11, 927–938 (2003). ArticleCASPubMed Google Scholar
Lyapina, S. et al. Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science292, 1382–1385 (2001). ArticleCASPubMed Google Scholar
Schwechheimer, C. et al. Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science292, 1379–1382 (2001). ArticleCASPubMed Google Scholar
Pan, Z.Q., Kentsis, A., Dias, D.C., Yamoah, K. & Wu, K. Nedd8 on cullin: building an expressway to protein destruction. Oncogene23, 1985–1997 (2004). ArticleCASPubMed Google Scholar
Cope, G.A. et al. Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science298, 608–611 (2002). ArticleCASPubMed Google Scholar
Mundt, K.E., Liu, C. & Carr, A.M. Deletion mutants in COP9/signalosome subunits in fission yeast schizosaccharomyces pombe display distinct phenotypes. Mol. Biol. Cell13, 493–502 (2002). ArticleCASPubMedPubMed Central Google Scholar
Liu, C. et al. Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms. Genes Dev.17, 1130–1140 (2003). ArticleCASPubMedPubMed Central Google Scholar
Wang, X. et al. CSN1 N-terminal-dependent activity is required for Arabidopsis development but not for Rub1/Nedd8 deconjugation of cullins: a structure-function study of CSN1 subunit of COP9 signalosome. Mol. Biol. Cell13, 646–655 (2002). ArticleCASPubMedPubMed Central Google Scholar
Rosel, D. & Kimmel, A.R. The COP9 signalosome regulates cell proliferation of Dictyostelium discoideum. Eur. J. Cell Biol.85, 1023–1034 (2006). ArticleCASPubMed Google Scholar
Wei, N. & Deng, X.W. COP9: a new genetic locus involved in light-regulated development and gene expression in Arabidopsis. Plant Cell4, 1507–1518 (1992). ArticleCASPubMedPubMed Central Google Scholar
Lykke-Andersen, K. et al. Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E and early embryonic death. Mol. Cell. Biol.23, 6790–6797 (2003). ArticleCASPubMedPubMed Central Google Scholar
Yan, J. et al. COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast. Mol. Cell. Biol.23, 6798–6808 (2003). ArticleCASPubMedPubMed Central Google Scholar
Tomoda, K., Yoneda-Kato, N., Fukumoto, A., Yamanaka, S. & Kato, J.Y. Multiple functions of Jab1 are required for early embryonic development and growth potential in mice. J. Biol. Chem.279, 43013–43018 (2004). ArticleCASPubMed Google Scholar
Lee, P.P. et al. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity15, 763–774 (2001). ArticleCASPubMed Google Scholar
Surh, C.D. & Sprent, J. Homeostatic T cell proliferation: how far can T cells be activated to self ligands? J. Exp. Med.192, F9–F14 (2000). ArticleCASPubMed Google Scholar
Jameson, S.C. Maintaining the norm: T-cell homeostasis. Nat. Rev. Immunol.2, 547–556 (2002). ArticleCASPubMed Google Scholar
Tough, D.F. & Sprent, J. Turnover of naive and memory-phenotype T cells. J. Exp. Med.179, 1127–1135 (1994). ArticleCASPubMed Google Scholar
Fry, T.J. & Mackall, C.L. The many faces of IL7: from lymphopoiesis to peripheral T cell maintenance. J. Immunol.174, 6571–6576 (2005). ArticleCASPubMed Google Scholar
Gudmundsdottir, H., Wells, A.D. & Turka, L.A. Dynamics and requirements of T cell clonal expansion in vivo at the single-cell level: effector function is linked to proliferative capacity. J. Immunol.162, 5212–5223 (1999). CASPubMed Google Scholar
Bjorklund, M. et al. Identification of pathways regulating cell size and cell-cycle progression by RNAi. Nature439, 1009–1013 (2006). ArticlePubMed Google Scholar
Cope, G.A. & Deshaies, R.J. Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels. BMC Biochem.9, 1 (2006). Article Google Scholar
Denti, S., Fernandez Sanchez, M.E., Rogge, L. & Bianchi, E. The COP9 signalsome regulates Skp2 levels and proliferation of human cells. J. Biol. Chem.281, 32188–32196 (2006). ArticleCASPubMed Google Scholar
Valerio Dorrello, N. et al. SCFßTRCP- and S6K1-mediated degradation of PDCD4 promotes protein translation and cell growth. Science314, 467–471 (2006). ArticlePubMed Google Scholar
Kim, S.Y., Herbst, A., Tworkowski, K.A., Salghetti, S.E. & Tansey, W.P. Skp2 regulates Myc protein stability and activity. Mol. Cell11, 1177–1188 (2003). ArticleCASPubMed Google Scholar
Von der Lehr, N. et al. The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. Mol. Cell11, 1189–1200 (2003). ArticleCASPubMed Google Scholar
Welcker, M. et al. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation. Proc. Natl. Acad. Sci. USA101, 9085–9090 (2004). ArticleCASPubMedPubMed Central Google Scholar
Bouchard, C. et al. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev.15, 2042–2047 (2001). ArticleCASPubMedPubMed Central Google Scholar
Wei, N. & Deng, X.W. Characterization and purification of the mammalian COP9 complex, a conserved nuclear regulator initially identified as a repressor of photomorphogenesis in higher plants. Photochem. Photobiol.68, 237–241 (1998). ArticleCASPubMed Google Scholar
Yoneda-Kato, N., Tomoda, K., Umehara, M., Arata, Y. & Kato, J.Y. Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3. EMBO J.24, 1739–1749 (2005). ArticleCASPubMedPubMed Central Google Scholar
Yang, X. et al. The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1. Curr. Biol.12, 667–672 (2002). ArticleCASPubMed Google Scholar
Inoue, Y., Kitagawa, M. & Taya, Y. Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage. EMBO J.26, 2083–2093 (2007). ArticleCASPubMedPubMed Central Google Scholar
Tomoda, K., Kubota, Y. & Kato, J. Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature398, 160–165 (1999). ArticleCASPubMed Google Scholar
Tomoda, K. et al. The Jab1/COP9 signalosome subcomplex is a downstream mediator of Bcr-Abl kinase activity and facilitates cell-cycle progression. Blood105, 775–783 (2005). ArticleCASPubMed Google Scholar
Fukumoto, A., Tomoda, K., Kubota, M., Kato, J.Y. & Yoneda-Kato, N. Small Jab1-containing subcomplex is regulated in an anchorage- and cell cycle-dependent manner, which is abrogated by ras transformation. FEBS Lett.579, 1047–1054 (2005). ArticleCASPubMed Google Scholar
Oron, E. et al. COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. Development129, 4399–4409 (2002). CASPubMed Google Scholar
Ullah, Z., Buckley, M.S., Arnosti, D.N. & Henry, R.W. Retinoblastoma protein regulation by the COP9 signalosome. Mol. Biol. Cell18, 1179–1186 (2007). ArticleCASPubMedPubMed Central Google Scholar
Collins, G.A. & Tansey, W.P. The proteasome: a utility tool for transcription? Curr. Opin. Genet. Dev.16, 197–202 (2006). ArticleCASPubMed Google Scholar