Research toward vaccines against malaria (original) (raw)

• Miller, L.H., Good, M.F. & Milon, G. Malaria pathogenesis. Science 264, 1878–1883 (1994).
  Article CAS Google Scholar
• Marsh, K. Malaria—a neglected disease? Parasitology 104, S53–S69 (1992).
  Article Google Scholar
• Snow, R.W. et al. Relation between severe malaria morbidity in children and level of Plasmodium falciparum transmission in Africa. Lancet 349, 1650–1654 (1997).
  Article CAS Google Scholar
• Hoffman, S.L. (ed.) Malaria Vaccine Development: A Multi-Immune Response Approach. Washington, D.C.: ASM Press (1996).
  Google Scholar
• Good, M.F., Kaslow, D.C. & Miller, L.H. Pathways and strategies for developing a malaria blood stage vaccine. Ann. Rev. Immunol. 16, 57–87 (1998).
  Article CAS Google Scholar
• Hoffman, S.L., Franke, E.D., Hollingdale, M.R. & Druilhe, P. Attacking the infected hepatocyte. In: Malaria Vaccine Development: A Multi-Immune Response Approach, Hoffman, S.L. (ed.) Washington, D.C: American Society of Microbiology, pp. 35–75 (1996).
  Google Scholar
• Doolan, D.L. et al. Degenerate cytotoxic T cell epitopes from Plasmodium falciparum restricted by multiple HLA-A and HLA-B supertype alleles. Immunity 7, 97–112 (1997).
  Article CAS Google Scholar
• Aggarwal, A. et al. Oral Salmonella: malaria circumsporozoite recombinants induce specific CD8+ cytotoxic T cells. J. Exp. Med. 172, 1083–1090 (1990).
  Article CAS Google Scholar
• Khusmith, S. et al. Protection against malaria by vaccination with sporozoite surface protein 2 plus CS protein. Science 252, 715–718 (1991).
  Article CAS Google Scholar
• Doolan, D.L. et al. Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon—, and nitric oxide-dependent immunity. J. Exp. Med. 183, 1739–1746 (1996).
  Article CAS Google Scholar
• Ockenhouse, C.F. et al. Phase I/IIa safety, immunogenicity, and efficacy of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria. J. Infect. Dis. (in the press).
• Hoffman, S.L. et al. Toward clinical trials of DNA vaccines against malaria. Immunol. Cell Biol. 75, 376–381 (1997).
  Article CAS Google Scholar
• Weiss, W. et al. A plasmid encoding murine GMCSF increases protection conferred by a malaria DNA vaccine. J. Immunol. (1998) (in press).
• Schneider, J. et al. Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara. Nature Med. 4, 397–402 (1998).
  Article CAS Google Scholar
• Sedegah, M. et al. Boosting with recombinant vaccinia increases immunogenicity and protective efficacy of malaria DNA vaccine. Proc. Natl. Acad. Sci. USA (1998) (in press).
• Rodrigues, E.G., Zavala, F., Eichinger, D., Wilson, J.M. & Tsuji, M. Single immunizing dose of recombinant adenovirus efficiently induces CD8+ T cell-mediated protective immunity against malaria. J. Immunol. 158, 1268–1274 (1997).
  CAS PubMed Google Scholar
• Gilbert, S.C. et al. Association of malaria parasite population structure, HLA, and immunological antagonism. Science 279, 1173–1177 (1998).
  Article CAS Google Scholar
• Sinnis, P. & Nussenzweig, V. Preventing sporozoite invasion of hepatocytes. In: Malaria Vaccine Development: a Multi-Immune Response Approach, Hoffman, S.L. (ed.) Washington, D.C: American Society of Microbiology, pp. 15–33 (1996).
  Google Scholar
• Herrington, D.A. et al. Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites. Nature 328, 257–259 (1987).
  Article CAS Google Scholar
• Ballou, W.R. et al. Safety and efficacy of a recombinant DNA Plasmodium falciparum sporozoite vaccine. Lancet 1, 1277–1281 (1987).
  Article CAS Google Scholar
• Stoute, J.A. et al. A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria. RTS, S Malaria Vaccine Evaluation Group. N. Engl. J. Med. 336, 86–91 (1997).
  Article CAS Google Scholar
• Stoute, J.A. et al. Long-term efficacy and immune responses following immunization with the RTS,S malaria vaccine. J. Infect. Dis. (1998) (in press).
• Renia, L. et al. In vitro activity of CD4+ and CD8+ lymphocytes frommice immunized with a synthetic malaria peptide. Proc. Natl. Acad. Sci. USA 88, 7963–7967 (1991).
  Article CAS Google Scholar
• Wang, R. et al. Protection against malaria by Plasmodium yoelii sporozoite surface protein 1 linear peptide induction of CD4+ T cell- and IFN-γ-dependent elimination of infected hepatocytes. J. Immunol. 157, 4061–4067 (1996).
  CAS PubMed Google Scholar
• Mitchell, G.H., Butcher, G.A. & Cohen, S. Merozoite vaccination against Plasmodium knowlesi malaria. Immunology 29, 397–407 (1975).
  CAS PubMed PubMed Central Google Scholar
• Smythe, J.A. et al. Identification of two integral membrane proteins of Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 85, 5195–5199 (1988).
  Article CAS Google Scholar
• Holder, A.A. & Freeman, R.R. Immunization against blood stage rodent malaria using purified parasite antigens. Nature 294, 361–366 (1982).
  Article Google Scholar
• Hirunpetcharat, C. et al. Complete protective immunity induced in mice by immunization with the 19-kilodalton carboxyl-terminal fragment of the merozoite surface protein (MSP119) of Plasmodium yoelii expressed in Saccharomyces cerevisiae: correlation of protection with antigen-specific antibody titer, but not with effector CD4+ T cells. J. Immunol. 159, 3400–3411 (1997).
  CAS PubMed Google Scholar
• Bouharoun-Taylor, H., Oeuvray, C., Lunel, F. & Druilhe, P. Mechanisms underlying the monocyte-mediated antibody-dependent killing of Plasmodium falciparum asexual blood stages. J. Exp. Med. 182, 409–418 (1995).
  Article Google Scholar
• Holder, A.A. Preventing merozoite invasion of erythrocytes. In: Malaria Vaccine Development: A Multi-Immune Response Approach, Hoffman, S.L. (ed.) Washington, D.C: American Society of Microbiology, pp. 77–104 (1996).
  Google Scholar
• Patarroyo, M.E. et al. Induction of protective immunity against experimental infection with malaria using synthetic peptides. Nature 328, 629–632 (1987).
  Article CAS Google Scholar
• Alonso, P.L. et al. Randomised trial of efficacy of SPf6 vaccine against Plasmodium falciparum malaria in children in southern Tanzania. Lancet 344, 1175–1181 (1994).
  Article CAS Google Scholar
• d'Allessandro, U. et al. Efficacy trial of malaria vaccine SPf66 in Gambian infants. Lancet 346, 462–467 (1995).
  Article Google Scholar
• Chitnis, C.E. & Miller, L.H. Identification of the erythrocyte binding domains of Plasmodium vivax and Plasmodium knowlesi proteins involved in erythrocyte invasion. J. Exp. Med. 180, 497–506 (1994).
  Article CAS Google Scholar
• Sim, B.K.L., Chitnis, C.E., Wasniowska, K., Hadley, T.J. & Miller, L.H. Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum. Science 264, 1941–1944 (1994).
  Article CAS Google Scholar
• Su, X.-Z. et al. The large diverse gene family var encodes proteins involved in the cytoadherence and antigenic variation of _Plasmodium fotoparum_-infected erythrocytes. Cell 82, 89–100 (1995).
  Article CAS Google Scholar
• Baruch, D.I. et al. Identification of a region of PfEMPI that mediates adherence of Plasmodium falciparum infected erythrocytes to CD36: conserved function with variant sequence. Blood 90, 3766–3775 (1997).
• Anders, R.F. Multiple cross-reactivities amongst antigens of Plasmodium falciparum impair the development of protective immunity against malaria. Parasite Immunol. 8, 529–539 (1986).
  Article CAS Google Scholar
• Wooton, J.C. Non-globular domains in protein sequence: automated segmentation using complexity measures. Computers Chem. 18, 269–285 (1994).
  Article Google Scholar
• Deans, J.A., et al. Vaccination trials in rhesus monkeys with a minor, invariant, Plasmodium knowlesi 66 kD merozoite antigen. Parasite Immunol. 10, 535–552 (1988).
  Article CAS Google Scholar