Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain (original) (raw)
Scolding, N. et al. Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis [see comments]. Brain121, 2221–2228 (1998). Article Google Scholar
Roy, N.S. et al. Identification, isolation, and promoter-defined separation of mitotic oligodendrocyte progenitor cells from the adult human subcortical white matter. J. Neurosci.19, 9986–9995 (1999). ArticleCAS Google Scholar
Gravel, M., DiPolo, A., Valera, P. & Braun, P. Four-kilobase sequence of the mouse CNP gene directs spatial and temporal expression of lacZ in transgenic mice. J. Neurosci. Res.53, 393–404 (1998). ArticleCAS Google Scholar
Kondo, T. & Raff, M. Oligodendrocyte precursor cells reprogrammed to become multipotential CNS stem cells. Science289, 1754–1757 (2000). ArticleCAS Google Scholar
Palmer, T.D., Markakis, E.A., Willhoite, A.R., Safar, F. & Gage, F.H. Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS. J. Neurosci.19, 8487–8497 (1999). ArticleCAS Google Scholar
Reynolds, B.A. & Weiss, S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science255, 1707–1710 (1992). ArticleCAS Google Scholar
Vescovi, A.L., Reynolds, B.A., Fraser, D.D. & Weiss, S. bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells. Neuron11, 951–966 (1993). ArticleCAS Google Scholar
Morshead, C.M. et al. Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells. Neuron13, 1071–1082 (1994). ArticleCAS Google Scholar
Vescovi, A. et al. Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human stem cells lines by epigenetic stimulation. Exp. Neurol.156, 71–83 (1999). ArticleCAS Google Scholar
Svendsen, C., Caldwell, M. & Ostenfeld, T. Human neural stem cells: isolation, expansion and transplantation. Brain Pathol.9, 499–513 (1999). ArticleCAS Google Scholar
Carpenter, M. et al. In vitro expansion of a multipotent population of human neural progenitor cells. Exp. Neurol.158, 265–278 (1999). ArticleCAS Google Scholar
Han, J. et al. Transgene expression in the guinea pig cochlea mediated by a lentivirus-derived gene transfer vector. Hum. Gene Ther.10, 1867–1873 (1999). ArticleCAS Google Scholar
Zufferey, R., Donello, J., Trono, D. & Hope, H. Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J. Virol.73, 2886–2892 (1999). CASPubMedPubMed Central Google Scholar
Windrem, M. et al. Progenitor cells derived from the adult human subcortical white matter disperse and differentiate as oligodendrocytes within demyelinated regions of the rat brain. J. Neurosci. Res.69, 966–975 (2002). ArticleCAS Google Scholar
Kang, J., Jiang, L., Goldman, S.A. & Nedergaard, M. Astrocyte-mediated potentiation of inhibitory synaptic transmission. Nat. Neurosci.1, 683–692 (1998). ArticleCAS Google Scholar
Tse, F.W., Fraser, D.D., Duffy, S. & MacVicar, B.A. Voltage-activated K+ currents in acutely isolated hippocampal astrocytes. J. Neurosci.12, 1781–1788 (1992). ArticleCAS Google Scholar
Barres, B.A. et al. A crucial role for neurotrophin-3 in oligodendrocyte development. Nature367, 371–375 (1994). ArticleCAS Google Scholar
Raff, M.C., Lillien, L.E., Richardson, W.D., Burne, J.F. & Noble, M.D. Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature333, 562–565 (1988). ArticleCAS Google Scholar
Vicario-Abejon, C., Johe, K.K., Hazel, T.G., Collazo, D. & McKay, R.D. Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Neuron15, 105–114 (1995). ArticleCAS Google Scholar
Johe, K.K., Hazel, T.G., Muller, T., Dugich-Djordjevic, M.M. & McKay, R.D. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Genes Dev.10, 3129–3140 (1996). ArticleCAS Google Scholar
Keyoung, H.M. et al. Specific identification, selection and extraction of neural stem cells from the fetal human brain. Nat. Biotechnol.19, 843–850 (2001). ArticleCAS Google Scholar
Yashima, K. et al. Expression of the RNA component of telomerase during human development and differentiation. Cell Growth Differ.9, 805–813 (1998). CASPubMed Google Scholar
Ostenfeld, T. et al. Human neural precursor cells express low levels of telomerase in vitro and show diminishing cell proliferation with extensive axonal outgrowth following transplantation. Exp. Neurol.164, 215–226 (2000). ArticleCAS Google Scholar
Kim, N. et al. Specific association of human telomerase activity with immortal cells and cancer. Science266, 2011–2015 (1994). ArticleCAS Google Scholar
Gleeson, J., Lin, P., Flanagan, L. & Walsh, C. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron23, 257–271 (1999). ArticleCAS Google Scholar
Doetsch, F., Caille, I., Lim, D., Garcia-Verdugo, J. & Alvarez-Buylla, A. Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell97, 703–716 (1999). ArticleCAS Google Scholar
Alvarez-Buylla, A. & Garcia-Verdugo, J.M. Neurogenesis in adult subventricular zone. J. Neurosci.22, 629–634 (2002). ArticleCAS Google Scholar
Kukekov, V., Laywell, E., Thomas, L. & Steindler, D. A nestin-negative precursor cell from the adult mouse brain gives rise to neurons and glia. Glia21, 399–407 (1997). ArticleCAS Google Scholar
Levine, J.M., Reynolds, R. & Fawcett, J.W. The oligodendrocyte precursor cell in health and disease. Trends Neurosci.24, 39–47 (2001). ArticleCAS Google Scholar
Mason, J. & Goldman, J. A2B5+ and O4+ cycling progenitors in the adult forebrain white matter respond differentially to PDGF-AA, FGF-2, and IGF-1. Molec. Cell. Neurosci.20, 30–42 (2002). ArticleCAS Google Scholar
Jiang, Y. et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature418, 41–49 (2002). ArticleCAS Google Scholar
Capela, A. & Temple, S. LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron35, 865–875 (2002). Article Google Scholar
Roy, N.S. et al. In vitro neurogenesis by progenitor cells isolated from the adult human hippocampus. Nat. Med.6, 271–277 (2000). ArticleCAS Google Scholar
Roy, N.S. et al. Promoter-targeted selection and isolation of neural progenitor cells from the adult human ventricular zone. J. Neurosci. Res.59, 321–331 (2000). ArticleCAS Google Scholar
Wang, S. et al. Isolation of neuronal precursors by sorting embryonic forebrain transfected with GFP regulated by the T α 1 tubulin promoter. Nat. Biotechnol.16, 196–201 (1998). ArticleCAS Google Scholar
Brustle, O. et al. Chimeric brains generated by intraventricular transplantation of fetal human brain cells into embryonic rats. Nat. Biotechnol.16, 1040–1044 (1998). ArticleCAS Google Scholar
Benraiss, A., Chmielnicki, E., Roh, D. & Goldman, S.A. Adenoviral BDNF induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain. J. Neurosci.21, 6718–6731 (2001). ArticleCAS Google Scholar
Kirschenbaum, B. et al. In vitro neuronal production and differentiation by precursor cells derived from the adult human forebrain. Cereb. Cortex4, 576–589 (1994). ArticleCAS Google Scholar
Pincus, D.W. et al. FGF2/BDNF-associated maturation of new neurons generated from adult human subependymal cells. Ann. Neurol.43, 576–585 (1998). ArticleCAS Google Scholar
Marusich, M., Furneaux, H., Henion, P. & Weston, J. Hu neuronal proteins are expressed in proliferating neurogenic cells. J. Neurobiol.25, 143–155 (1994). ArticleCAS Google Scholar
Barami, K., Iversen, K., Furneaux, H. & Goldman, S.A. Hu protein as an early marker of neuronal phenotypic differentiation by subependymal zone cells of the adult songbird forebrain. J. Neurobiol.28, 82–101 (1995). ArticleCAS Google Scholar