Site-specific recombination in human embryonic stem cells induced by cell-permeant Cre recombinase (original) (raw)
Smith, A.G. Embryo-derived stem cells: of mice and men. Annu. Rev. Cell Dev. Biol.17, 435–462 (2001). ArticleCAS Google Scholar
Thomson, J.A. et al. Embryonic stem cell lines derived from human blastocysts. Science282, 1145–1147 (1998). ArticleCAS Google Scholar
Amit, M. et al. Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture. Dev. Biol.227, 271–278 (2000). ArticleCAS Google Scholar
Brüstle, O. et al. Embryonic stem cell-derived glial precursors: a source of myelinating transplants. Science285, 754–756 (1999). Article Google Scholar
Blyszczuk, P. et al. Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells. Proc. Natl. Acad. Sci. USA100, 998–1003 (2003). ArticleCAS Google Scholar
Andersson, E. et al. Identification of intrinsic determinants of midbrain dopamine neurons. Cell124, 393–405 (2006). ArticleCAS Google Scholar
Klug, M.G., Soonpaa, M.H., Koh, G.Y. & Field, L.J. Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts. J. Clin. Invest.98, 216–224 (1996). ArticleCAS Google Scholar
Li, M., Pevny, L., Lovell-Badge, R. & Smith, A. Generation of purified neural precursors from embryonic stem cells by lineage selection. Curr. Biol.8, 971–974 (1998). ArticleCAS Google Scholar
Branda, C.S. & Dymecki, S.M. Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev. Cell6, 7–28 (2004). ArticleCAS Google Scholar
Lewandoski, M. Conditional control of gene expression in the mouse. Nat. Rev. Genet.2, 743–755 (2001). ArticleCAS Google Scholar
Buch, T. et al. A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration. Nat. Methods2, 419–426 (2005). ArticleCAS Google Scholar
Tan, S.M. & Droge, P. Comparative analysis of sequence-specific DNA recombination systems in human embryonic stem cells. Stem Cells23, 868–873 (2005). ArticleCAS Google Scholar
Nagahara, H. et al. Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nat. Med.4, 1449–1452 (1998). ArticleCAS Google Scholar
Jo, D. et al. Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nat. Biotechnol.19, 929–933 (2001). ArticleCAS Google Scholar
Peitz, M., Pfannkuche, K., Rajewsky, K. & Edenhofer, F. Ability of the hydrophobic FGF and basic TAT peptides to promote cellular uptake of recombinant Cre recombinase: a tool for efficient genetic engineering of mammalian genomes. Proc. Natl. Acad. Sci. USA99, 4489–4494 (2002). ArticleCAS Google Scholar
Will, E. et al. Unmodified Cre recombinase crosses the membrane. Nucleic Acids Res.30, e59 (2002). Article Google Scholar
Joshi, S.K., Hashimoto, K. & Koni, P.A. Induced DNA recombination by Cre recombinase protein transduction. Genesis33, 48–54 (2002). ArticleCAS Google Scholar
Zhang, S.C., Wernig, M., Duncan, I.D., Brüstle, O. & Thomson, J.A. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat. Biotechnol.19, 1129–1133 (2001). ArticleCAS Google Scholar
Eiges, R. et al. Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells. Curr. Biol.11, 514–518 (2001). ArticleCAS Google Scholar
Lakshmipathy, U. et al. Efficient transfection of embryonic and adult stem cells. Stem Cells22, 531–543 (2004). Article Google Scholar
Glover, D.J., Lipps, H.J. & Jans, D.A. Towards safe, non-viral therapeutic gene expression in humans. Nat. Rev. Genet.6, 299–310 (2005). ArticleCAS Google Scholar
Hacein-Bey-Abina, S. et al. A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med.348, 255–256 (2003). Article Google Scholar
Schmidt, E.E., Taylor, D.S., Prigge, J.R., Barnett, S. & Capecchi, M.R. Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids. Proc. Natl. Acad. Sci. USA97, 13702–13707 (2000). ArticleCAS Google Scholar
Loonstra, A. et al. Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells. Proc. Natl. Acad. Sci. USA98, 9209–9214 (2001). ArticleCAS Google Scholar
Pfeifer, A., Brandon, E.P., Kootstra, N., Gage, F.H. & Verma, I.M. Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo. Proc. Natl. Acad. Sci. USA98, 11450–11455 (2001). ArticleCAS Google Scholar
Zwaka, T.P. Homologous recombination in human embryonic stem cells. Nat. Biotechnol.21, 319–321 (2003). ArticleCAS Google Scholar
Wunderlich, F.T., Wildner, H., Rajewsky, K. & Edenhofer, F. New variants of inducible Cre recombinase: a novel mutant of Cre-PR fusion protein exhibits enhanced sensitivity and an expanded range of inducibility. Nucleic Acids Res.29, e47 (2001). ArticleCAS Google Scholar
Stojkovic, P. et al. An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells. Stem Cells23, 306–314 (2005). ArticleCAS Google Scholar