Bi-directional effects of GABAB receptor agonists on the mesolimbic dopamine system (original) (raw)

• Robbins, T.W. & Everitt, B.J. Drug addiction: bad habits add up. Nature 398, 567–570 (1999).
  Article CAS Google Scholar
• Brebner, K., Childress, A.R. & Roberts, D.C. A potential role for GABAB agonists in the treatment of psychostimulant addiction. Alcohol Alcohol 37, 478–484 (2002).
  Article CAS Google Scholar
• Cousins, M.S., Roberts, D.C. & de Wit, H. GABAB receptor agonists for the treatment of drug addiction: a review of recent findings. Drug Alcohol Depend. 65, 209–220 (2002).
  Article CAS Google Scholar
• Martellotta, M.C., Cossu, G., Fattore, L., Gessa, G.L. & Fratta, W. Intravenous self-administration of gamma-hydroxybutyric acid in drug-naive mice. Eur. Neuropsychopharmacol. 8, 293–296 (1998).
  Article CAS Google Scholar
• Nicholson, K.L. & Balster, R.L. GHB: a new and novel drug of abuse. Drug Alcohol Depend. 63, 1–22 (2001).
  Article CAS Google Scholar
• Johnson, S.W. & North, R.A. Opioids excite dopamine neurons by hyperpolarization of local interneurons. J. Neurosci. 12, 483–488 (1992).
  Article CAS Google Scholar
• McFarland, K. & Kalivas, P.W. The circuitry mediating cocaine-induced reinstatement of drug-seeking behavior. J. Neurosci. 21, 8655–8663 (2001).
  Article CAS Google Scholar
• Lüscher, C., Jan, L.Y., Stoffel, M., Malenka, R.C. & Nicoll, R.A. G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron 19, 687–695 (1997).
  Article Google Scholar
• Patel, A.J. & Honore, E. Properties and modulation of mammalian 2P domain K+ channels. Trends Neurosci. 24, 339–346 (2001).
  Article CAS Google Scholar
• Krapivinsky, G. et al. The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K+-channel proteins. Nature 374, 135–141 (1995).
  Article CAS Google Scholar
• Lesage, F. et al. Cloning provides evidence for a family of inward rectifier and G-protein coupled K+ channels in the brain. FEBS Lett. 353, 37–42 (1994).
  Article CAS Google Scholar
• Dascal, N. et al. Atrial G protein-activated K+ channel: expression cloning and molecular properties. Proc. Natl. Acad. Sci. USA 90, 10235–10239 (1993).
  Article CAS Google Scholar
• Kubo, Y., Reuveny, E., Slesinger, P.A., Jan, Y.N. & Jan, L.Y. Primary structure and functional expression of a rat G-protein-coupled muscarinic potassium channel. Nature 364, 802–806 (1993).
  Article CAS Google Scholar
• Wickman, K., Pu, W.T. & Clapham, D.E. Structural characterization of the mouse Girk genes. Gene 284, 241–250 (2002).
  Article CAS Google Scholar
• Liao, Y.J., Jan, Y.N. & Jan, L.Y. Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain. J. Neurosci. 16, 7137–7150 (1996).
  Article CAS Google Scholar
• Jelacic, T.M., Sims, S.M. & Clapham, D.E. Functional expression and characterization of G-protein-gated inwardly rectifying K+ channels containing GIRK3. J. Membr. Biol. 169, 123–129 (1999).
  Article CAS Google Scholar
• Schoots, O. et al. Co-expression of human Kir3 subunits can yield channels with different functional properties. Cell Signal 11, 871–883 (1999).
  Article CAS Google Scholar
• Slesinger, P.A. et al. Functional effects of the mouse weaver mutation on G protein-gated inwardly rectifying K+ channels. Neuron 16, 321–331 (1996).
  Article CAS Google Scholar
• Inanobe, A. et al. Characterization of G-protein-gated K+ channels composed of Kir3.2 subunits in dopaminergic neurons of the substantia nigra. J. Neurosci. 19, 1006–1017 (1999).
  Article CAS Google Scholar
• Jelacic, T.M., Kennedy, M.E., Wickman, K. & Clapham, D.E. Functional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3. J. Biol. Chem. 275, 36211–36216 (2000).
  Article CAS Google Scholar
• Lesage, F. et al. Molecular properties of neuronal G-protein-activated inwardly rectifying K+ channels. J. Biol. Chem. 270, 28660–28667 (1995).
  Article CAS Google Scholar
• Wei, J. et al. Characterization of murine Girk2 transcript isoforms: structure and differential expression. Genomics 51, 379–390 (1998).
  Article CAS Google Scholar
• Lingenhoehl, K. et al. Gamma-hydroxybutyrate is a weak agonist at recombinant GABAB receptors. Neuropharmacol. 38, 1667–1673 (1999).
  Article CAS Google Scholar
• Madden, T.E. & Johnson, S.W. Gamma-hydroxybutyrate is a GABAB receptor agonist that increases a potassium conductance in rat ventral tegmental dopamine neurons. J. Pharm. Exp. Ther. 287, 261–265 (1998).
  CAS Google Scholar
• Carter, L.P. et al. The role of GABAB receptors in the discriminative stimulus effects of gamma-hydroxybutyrate in rats: time course and antagonism studies. J. Pharm. Exp. Ther. 305, 668–674 (2003).
  Article CAS Google Scholar
• White, J.H. et al. Heterodimerization is required for the formation of a functional GABAB receptor. Nature 396, 679–682 (1998).
  Article CAS Google Scholar
• Kaupmann, K. et al. GABAB-receptor subtypes assemble into functional heteromeric complexes. Nature 396, 683–687 (1998).
  Article CAS Google Scholar
• Schuler, V. et al. Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABAB responses in mice lacking GABAB1. Neuron 31, 47–58 (2001).
  Article CAS Google Scholar
• Billinton, A., Upton, N. & Bowery, N.G. GABAB receptor isoforms GBR1a and GBR1b, appear to be associated with pre- and post-synaptic elements respectively in rat and human cerebellum. Br. J. Pharmacol. 126, 1387–1392 (1999).
  Article CAS Google Scholar
• Brauner-Osborne, H. & Krogsgaard-Larsen, P. Functional pharmacology of cloned heterodimeric GABAB receptors expressed in mammalian cells. Br. J. Pharmacol. 128, 1370–1374 (1999).
  Article CAS Google Scholar
• Pfaff, T. et al. Alternative splicing generates a novel isoform of the rat metabotropic GABABR1 receptor. Eur. J. Neurosci. 11, 2874–2882 (1999).
  Article CAS Google Scholar
• Karschin, C., Dissmann, E., Stuhmer, W. & Karschin, A. IRK(1–3) and GIRK(1–4) inwardly rectifying K+ channel mRNAs are differentially expressed in the adult rat brain. J. Neurosci. 16, 3559–3570 (1996).
  Article CAS Google Scholar
• Wickman, K., Karschin, C., Karschin, A., Picciotto, M.R. & Clapham, D.E. Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4. J. Neurosci. 20, 5608–5615 (2000).
  Article CAS Google Scholar
• Torrecilla, M. et al. G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons. J. Neurosci. 22, 4328–4334 (2002).
  Article CAS Google Scholar
• Ma, D. et al. Diverse trafficking patterns due to multiple traffic motifs in G protein-activated inwardly rectifying potassium channels from brain and heart. Neuron 33, 715–729 (2002).
  Article CAS Google Scholar
• Jeong, S.W. & Ikeda, S.R. Endogenous regulator of G-protein signaling proteins modify N-type calcium channel modulation in rat sympathetic neurons. J. Neurosci. 20, 4489–4496 (2000).
  Article CAS Google Scholar
• Huang, C.L., Feng, S. & Hilgemann, D.W. Direct activation of inward rectifier potassium channels by PIP2 and its stabilization by Gbetagamma. Nature 391, 803–806 (1998).
  Article CAS Google Scholar
• Logothetis, D.E., Kurachi, Y., Galper, J., Neer, E.J. & Clapham, D.E. The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. Nature 325, 321–326 (1987).
  Article CAS Google Scholar
• Reuveny, E. et al. Activation of the cloned muscarinic potassium channel by G protein beta gamma subunits. Nature 370, 143–146 (1994).
  Article CAS Google Scholar
• Johnson, S.W. & North, R.A. Two types of neurone in the rat ventral tegmental area and their synaptic inputs. J. Physiol. (Lond.) 450, 455–468 (1992).
  Article CAS Google Scholar
• Sugita, S., Johnson, S.W. & North, R.A. Synaptic inputs to GABAA and GABAB receptors originate from discrete afferent neurons. Neurosci. Lett. 134, 207–211 (1992).
  Article CAS Google Scholar
• Matindale – The Complete Drug Reference p. 2496 (The Pharmaceutical Press, 2002).
• Kalivas, P.W. Neurotransmitter regulation of dopamine neurons in the ventral tegmental area. Brain Res. Brain Res. Rev. 18, 75–113 (1993).
  Article CAS Google Scholar
• Kalivas, P.W., Duffy, P. & Eberhardt, H. Modulation of A10 dopamine neurons by gamma-aminobutyric acid agonists. J. Pharm. Exp. Ther. 253, 858–866 (1990).
  CAS Google Scholar
• Feigenbaum, J.J. & Howard, S.G. Does gamma-hydroxybutyrate inhibit or stimulate central DA release? Int. J. Neurosci. 88, 53–69 (1996).
  Article CAS Google Scholar
• Gallimberti, L. et al. Gamma-hydroxybutyric acid for treatment of alcohol withdrawal syndrome. Lancet 2, 787–789 (1989).
  Article CAS Google Scholar
• Snead, O.C. III. Evidence for a G protein-coupled gamma-hydroxybutyric acid receptor. J. Neurochem. 75, 1986–1996 (2000).
  Article CAS Google Scholar
• Andriamampandry, C. et al. Cloning and characterization of a rat brain receptor that binds the endogenous neuromodulator gamma-hydroxybutyrate (GHB). FASEB J. 17, 1691–1693 (2003).
  Article CAS Google Scholar
• Quéva, C. et al. Effects of GABA agonists on body temperature regulation in GABAB(1)−/− mice. Brit. J. Pharmacol. 140, 315–322 (2003).
  Article Google Scholar
• Kaupmann, K. et al. Specific γ-hydroxybutyrate (GHB) binding sites but loss of pharmacological effects of GHB in GABAB(1) deficient mice. Eur. J. Neurosci. 18, 2722–2730 (2003).
  Article Google Scholar