Central amygdala ERK signaling pathway is critical to incubation of cocaine craving (original) (raw)
O'Brien, C.P. A range of research-based pharmacotherapies for addiction. Science278, 66–70 (1997). ArticleCAS Google Scholar
Gawin, F.H. & Kleber, H.D. Abstinence symptomatology and psychiatric diagnosis in cocaine abusers. Clinical observations. Arch. Gen. Psychiatry43, 107–113 (1986). ArticleCAS Google Scholar
Grimm, J.W., Hope, B.T., Wise, R.A. & Shaham, Y. Incubation of cocaine craving after withdrawal. Nature412, 141–142 (2001). ArticleCASPubMed Google Scholar
Lu, L., Grimm, J.W., Dempsey, J. & Shaham, Y. Cocaine seeking over extended withdrawal periods in rats: different time courses of responding induced by cocaine cues versus cocaine priming over the first 6 months. Psychopharmacology (Berl.)176, 101–108 (2004). ArticleCAS Google Scholar
Neisewander, J.L. et al. Fos protein expression and cocaine-seeking behavior in rats after exposure to a cocaine self-administration environment. J. Neurosci.20, 798–805 (2000). ArticleCAS Google Scholar
Nestler, E.J. Molecular basis of long-term plasticity underlying addiction. Nat. Rev. Neurosci.2, 119–128 (2001). ArticleCAS Google Scholar
Kalivas, P.W. Glutamate systems in cocaine addiction. Curr. Opin. Pharmacol.4, 23–29 (2004). ArticleCAS Google Scholar
Stewart, J. Pathways to relapse: factors controlling the reinitiation of drug seeking after abstinence. Nebr. Symp. Motiv.50, 197–234 (2004). Google Scholar
Everitt, B.J. & Wolf, M.E. Psychomotor stimulant addiction: a neural systems perspective. J. Neurosci.22, 3312–3320 (2002). ArticleCAS Google Scholar
Grimm, J.W. et al. Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving. J. Neurosci.23, 742–747 (2003). ArticleCAS Google Scholar
Lu, L., Grimm, J.W., Shaham, Y. & Hope, B.T. Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self-administration in rats. J. Neurochem.85, 1604–1613 (2003). ArticleCAS Google Scholar
Lu, L., Dempsey, J., Liu, S.Y., Bossert, J.M. & Shaham, Y. A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal. J. Neurosci.24, 1604–1611 (2004). ArticleCAS Google Scholar
Lu, L., Grimm, J.W., Hope, B.T. & Shaham, Y. Incubation of cocaine craving after withdrawal: a review of preclinical data. Neuropharmacology47 (Suppl. 1), 214–226 (2004). ArticleCAS Google Scholar
Berhow, M.T., Hiroi, N. & Nestler, E.J. Regulation of ERK (extracellular signal regulated kinase), part of the neurotrophin signal transduction cascade, in the rat mesolimbic dopamine system by chronic exposure to morphine or cocaine. J. Neurosci.16, 4707–4715 (1996). ArticleCAS Google Scholar
Valjent, E. et al. Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties. J. Neurosci.20, 8701–8709 (2000). ArticleCAS Google Scholar
Licata, S.C. & Pierce, R.C. The roles of calcium/calmodulin-dependent and Ras/mitogen-activated protein kinases in the development of psychostimulant-induced behavioral sensitization. J. Neurochem.85, 14–22 (2003). ArticleCAS Google Scholar
Thomas, G.M. & Huganir, R.L. MAPK cascade signalling and synaptic plasticity. Nat. Rev. Neurosci.5, 173–183 (2004). ArticleCAS Google Scholar
Adams, J.P. & Sweatt, J.D. Molecular psychology: roles for the ERK MAP kinase cascade in memory. Annu. Rev. Pharmacol. Toxicol.42, 135–163 (2002). ArticleCAS Google Scholar
Schafe, G.E. et al. Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of pavlovian fear conditioning. J. Neurosci.20, 8177–8187 (2000). ArticleCAS Google Scholar
Lu, K.T., Walker, D.L. & Davis, M. Mitogen-activated protein kinase cascade in the basolateral nucleus of amygdala is involved in extinction of fear-potentiated startle. J. Neurosci.21, RC162 (2001). ArticleCAS Google Scholar
LeDoux, J.E. Emotion circuits in the brain. Annu. Rev. Neurosci.23, 155–184 (2000). ArticleCAS Google Scholar
Gallagher, M. & Chiba, A.A. The amygdala and emotion. Curr. Opin. Neurobiol.6, 221–227 (1996). ArticleCAS Google Scholar
Everitt, B.J. et al. Associative processes in addiction and reward. The role of amygdala-ventral striatal subsystems. Ann. NY Acad. Sci.877, 412–438 (1999). ArticleCAS Google Scholar
See, R.E. Neural substrates of conditioned-cued relapse to drug-seeking behavior. Pharmacol. Biochem. Behav.71, 517–529 (2002). ArticleCAS Google Scholar
Shaham, Y., Shalev, U., Lu, L., De Wit, H. & Stewart, J. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology (Berl.)168, 3–20 (2003). ArticleCAS Google Scholar
Shalev, U., Grimm, J.W. & Shaham, Y. Neurobiology of relapse to heroin and cocaine seeking: a review. Pharmacol. Rev.54, 1–42 (2002). ArticleCAS Google Scholar
Balleine, B.W. & Dickinson, A. Goal-directed instrumental action: contingency and incentive learning and their cortical substrates. Neuropharmacology37, 407–419 (1998). ArticleCAS Google Scholar
Davies, S.P., Reddy, H., Caivano, M. & Cohen, P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J.351, 95–105 (2000). ArticleCASPubMed Google Scholar
Fiore, R.S., Murphy, T.H., Sanghera, J.S., Pelech, S.L. & Baraban, J.M. Activation of p42 mitogen-activated protein kinase by glutamate receptor stimulation in rat primary cortical cultures. J. Neurochem.61, 1626–1633 (1993). ArticleCAS Google Scholar
Jentsch, J.D. & Taylor, J.R. Impulsivity resulting from frontostriatal dysfunction in drug abuse: implications for the control of behavior by reward-related stimuli. Psychopharamacology146, 373–390 (1999). ArticleCAS Google Scholar
Burns, L.H., Robbins, T.W. & Everitt, B.J. Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and medial prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions of D-amphetamine. Behav. Brain Res.55, 167–183 (1993). ArticleCAS Google Scholar
Robledo, P., Robbins, T.W. & Everitt, B.J. Effects of excitotoxic lesions of the central amygdaloid nucleus on the potentiation of reward-related stimuli by intra-accumbens amphetamine. Behav. Neurosci.110, 981–990 (1996). ArticleCAS Google Scholar
Wolf, M.E., Sun, X., Mangiavacchi, S. & Chao, S.Z. Psychomotor stimulants and neuronal plasticity. Neuropharmacology47 (Suppl. 1), 61–79 (2004). ArticleCAS Google Scholar
Holland, P.C. & Gallagher, M. Double dissociation of the effects of lesions of basolateral and central amygdala on conditioned stimulus-potentiated feeding and Pavlovian-instrumental transfer. Eur. J. Neurosci.17, 1680–1694 (2003). Article Google Scholar
Ungless, M.A., Whistler, J.L., Malenka, R.C. & Bonci, A. Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons. Nature411, 583–587 (2001). ArticleCAS Google Scholar
Thomas, M.J., Beurrier, C., Bonci, A. & Malenka, R.C. Long-term depression in the nucleus accumbens: a neural correlate of behavioral sensitization to cocaine. Nat. Neurosci.4, 1217–1223 (2001). ArticleCAS Google Scholar
Baker, D.A. et al. Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse. Nat. Neurosci.6, 743–749 (2003). ArticleCAS Google Scholar
Wise, R.A. & Hoffman, D.C. Localization of drug reward mechanisms by intracranial injections. Synapse10, 247–263 (1992). ArticleCASPubMed Google Scholar
Overton, D.A. Experimental methods for the study of state-dependent learning. Fed. Proc.33, 1800–1813 (1974). CAS Google Scholar
Whitelaw, R.B., Markou, A., Robbins, T.W. & Everitt, B.J. Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement. Psychopharmacology (Berl.)127, 213–224 (1996). ArticleCAS Google Scholar
Davis, M., Walker, D.L. & Myers, K.M. Role of the amygdala in fear extinction measured with potentiated startle. Ann. NY Acad. Sci.985, 218–232 (2003). ArticleCAS Google Scholar
Berman, D.E. & Dudai, Y. Memory extinction, learning anew, and learning the new: dissociations in the molecular machinery of learning in cortex. Science291, 2417–2419 (2001). ArticleCAS Google Scholar
Nestler, E.J. Common molecular and cellular substrates of addiction and memory. Neurobiol. Learn. Mem.78, 637–647 (2002). ArticleCAS Google Scholar
Sweatt, J.D. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J. Neurochem.76, 1–10 (2001). ArticleCAS Google Scholar
Grant, S. et al. Activation of memory circuits during cue-elicited cocaine craving. Proc. Natl. Acad. Sci. USA93, 12040–12045 (1996). ArticleCAS Google Scholar
Eysenck, H.J. A theory of the incubation of anxiety-fear responses. Behav. Res. Ther.6, 309–321 (1968). ArticleCAS Google Scholar
Paxinos, G. & Watson, C. The Rat Brain in Stereotaxic Coordinates (Academic, San Diego, 1998). Google Scholar
Hayes, R.J., Vorel, S.R., Spector, J., Liu, X. & Gardner, E.L. Electrical and chemical stimulation of the basolateral complex of the amygdala reinstates cocaine-seeking behavior in the rat. Psychopharmacology (Berl.)168, 75–83 (2003). ArticleCAS Google Scholar
Kelleher, R.J. III, Govindarajan, A., Jung, H.Y., Kang, H. & Tonegawa, S. Translational control by MAPK signaling in long-term synaptic plasticity and memory. Cell116, 467–479 (2004). ArticleCAS Google Scholar