Inducible gene targeting in the neonatal vasculature and analysis of retinal angiogenesis in mice (original) (raw)

• Risau, W. & Flamme, I. Vasculogenesis. Annu. Rev. Cell Dev. Biol. 11, 73–91 (1995).
  Article CAS PubMed Google Scholar
• Adams, R.H. & Alitalo, K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat. Rev. Mol. Cell Biol. 8, 464–478 (2007).
  Article CAS PubMed Google Scholar
• Staton, C.A., Reed, M.W. & Brown, N.J. A critical analysis of current in vitro and in vivo angiogenesis assays. Int. J. Exp. Pathol. 90, 195–221 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Glaser, B.M., D'Amore, P.A., Seppa, H., Seppa, S. & Schiffmann, E. Adult tissues contain chemoattractants for vascular endothelial cells. Nature 288, 483–484 (1980).
  Article CAS PubMed Google Scholar
• Alessandri, G., Raju, K. & Gullino, P.M. Mobilization of capillary endothelium in vitro induced by effectors of angiogenesis in vivo. Cancer Res. 43, 1790–1797 (1983).
  CAS PubMed Google Scholar
• Boyden, S. The chemotactic effect of mixtures of antibody and antigen on polymorphonuclear leucocytes. J. Exp. Med. 115, 453–466 (1962).
  Article CAS PubMed PubMed Central Google Scholar
• Wong, M.K. & Gotlieb, A.I. In vitro reendothelialization of a single-cell wound. Role of microfilament bundles in rapid lamellipodia-mediated wound closure. Lab. Invest. 51, 75–81 (1984).
  CAS PubMed Google Scholar
• Gospodarowicz, D., Moran, J., Braun, D. & Birdwell, C. Clonal growth of bovine vascular endothelial cells: fibroblast growth factor as a survival agent. Proc. Natl. Acad. Sci. USA 73, 4120–4124 (1976).
  Article CAS PubMed PubMed Central Google Scholar
• Kubota, Y., Kleinman, H.K., Martin, G.R. & Lawley, T.J. Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structures. J. Cell Biol. 107, 1589–1598 (1988).
  Article CAS PubMed Google Scholar
• Lawley, T.J. & Kubota, Y. Induction of morphologic differentiation of endothelial cells in culture. J. Invest. Dermatol. 93, S59–S61 (1989).
  Article Google Scholar
• Bayless, K.J., Kwak, H.I. & Su, S.C. Investigating endothelial invasion and sprouting behavior in three-dimensional collagen matrices. Nat. Protoc. 4, 1888–1898 (2009).
  Article CAS PubMed Google Scholar
• Nicosia, R.F. & Ottinetti, A. Modulation of microvascular growth and morphogenesis by reconstituted basement membrane gel in three-dimensional cultures of rat aorta: a comparative study of angiogenesis in matrigel, collagen, fibrin, and plasma clot. In Vitro Cell Dev. Biol. 26, 119–128 (1990).
  Article CAS PubMed Google Scholar
• Aplin, A.C., Fogel, E., Zorzi, P. & Nicosia, R.F. The aortic ring model of angiogenesis. Methods Enzymol. 443, 119–136 (2008).
  Article CAS PubMed Google Scholar
• Swaim, W.R. & Feders, M.B. Fibrinogen assay. Clin. Chem. 13, 1026–1028 (1967).
  Article CAS PubMed Google Scholar
• Chalupowicz, D.G., Chowdhury, Z.A., Bach, T.L., Barsigian, C. & Martinez, J. Fibrin II induces endothelial cell capillary tube formation. J. Cell Biol. 130, 207–215 (1995).
  Article CAS PubMed Google Scholar
• Bayless, K.J. & Davis, G.E. Sphingosine-1-phosphate markedly induces matrix metalloproteinase and integrin-dependent human endothelial cell invasion and lumen formation in three-dimensional collagen and fibrin matrices. Biochem. Biophys. Res. Commun. 312, 903–913 (2003).
  Article CAS PubMed Google Scholar
• Koh, W., Stratman, A.N., Sacharidou, A. & Davis, G.E. In vitro three dimensional collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis. Methods Enzymol. 443, 83–101 (2008).
  Article CAS PubMed Google Scholar
• Stratman, A.N. et al. Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices. Blood 114, 237–247 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Gimbrone, M.A. Jr. Cotran, R.S., Leapman, S.B. & Folkman, J. Tumor growth and neovascularization: an experimental model using the rabbit cornea. J. Natl. Cancer Inst. 52, 413–427 (1974).
  Article PubMed Google Scholar
• Fournier, G.A., Lutty, G.A., Watt, S., Fenselau, A. & Patz, A. A corneal micropocket assay for angiogenesis in the rat eye. Invest. Ophthalmol. Vis. Sci. 21, 351–354 (1981).
  CAS PubMed Google Scholar
• Auerbach, R., Kubai, L., Knighton, D. & Folkman, J. A simple procedure for the long-term cultivation of chicken embryos. Dev. Biol. 41, 391–394 (1974).
  Article CAS PubMed Google Scholar
• Ribatti, D., Vacca, A., Roncali, L. & Dammacco, F. The chick embryo chorioallantoic membrane as a model for in vivo research on angiogenesis. Int. J. Dev. Biol. 40, 1189–1197 (1996).
  CAS PubMed Google Scholar
• Dohle, D.S. et al. Chick ex ovo culture and ex ovo CAM assay: how it really works. J. Vis. Exp. doi:10.3791/1620 (2009).
• Alajati, A. et al. Spheroid-based engineering of a human vasculature in mice. Nat. Methods 5, 439–445 (2008).
  Article CAS PubMed Google Scholar
• Laib, A.M. et al. Spheroid-based human endothelial cell microvessel formation in vivo. Nat. Protoc. 4, 1202–1215 (2009).
  Article CAS PubMed Google Scholar
• Martin, P. Wound healing—aiming for perfect skin regeneration. Science 276, 75–81 (1997).
  Article CAS PubMed Google Scholar
• Eming, S.A., Brachvogel, B., Odorisio, T. & Koch, M. Regulation of angiogenesis: wound healing as a model. Prog. Histochem. Cytochem. 42, 115–170 (2007).
  Article CAS PubMed Google Scholar
• Papenfuss, H.D., Gross, J.F., Intaglietta, M. & Treese, F.A. A transparent access chamber for the rat dorsal skin fold. Microvasc. Res. 18, 311–318 (1979).
  Article CAS PubMed Google Scholar
• Vajkoczy, P. et al. Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy. Neoplasia 1, 31–41 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Endrich, B., Asaishi, K., Gotz, A. & Messmer, K. Technical report—a new chamber technique for microvascular studies in unanesthetized hamsters. Res. Exp. Med. (Berl.) 177, 125–134 (1980).
  Article CAS PubMed Google Scholar
• Swift, M.R. & Weinstein, B.M. Arterial-venous specification during development. Circ. Res. 104, 576–588 (2009).
  Article CAS PubMed Google Scholar
• Gariano, R.F. & Gardner, T.W. Retinal angiogenesis in development and disease. Nature 438, 960–966 (2005).
  Article CAS PubMed Google Scholar
• Fukumura, D. & Jain, R.K. Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization. Microvasc. Res. 74, 72–84 (2007).
  Article CAS PubMed PubMed Central Google Scholar
• Kerbel, R.S. Tumor angiogenesis: past, present and the near future. Carcinogenesis 21, 505–515 (2000).
  Article CAS PubMed Google Scholar
• Carmeliet, P. & Collen, D. Transgenic mouse models in angiogenesis and cardiovascular disease. J. Pathol. 190, 387–405 (2000).
  Article CAS PubMed Google Scholar
• Naumov, G.N., Akslen, L.A. & Folkman, J. Role of angiogenesis in human tumor dormancy: animal models of the angiogenic switch. Cell Cycle 5, 1779–1787 (2006).
  Article CAS PubMed Google Scholar
• Rocha, S.F. & Adams, R.H. Molecular differentiation and specialization of vascular beds. Angiogenesis 12, 139–147 (2009).
  Article CAS PubMed Google Scholar
• Connor, K.M. et al. Quantification of oxygen-induced retinopathy in the mouse: a model of vessel loss, vessel regrowth and pathological angiogenesis. Nat. Protoc. 4, 1565–1573 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Benedito, R. et al. The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis. Cell 137, 1124–1135 (2009).
  Article CAS PubMed Google Scholar
• Wang, Y. et al. Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis. Nature 465, 483–486 (2010).
  Article CAS PubMed Google Scholar
• Branda, C.S. & Dymecki, S.M. Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev. Cell 6, 7–28 (2004).
  Article CAS PubMed Google Scholar
• Sauer, B. & Henderson, N. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA 85, 5166–5170 (1988).
  Article CAS PubMed PubMed Central Google Scholar
• Sauer, B. & Henderson, N. Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase. New Biol. 2, 441–449 (1990).
  CAS PubMed Google Scholar
• Feil, R. et al. Ligand-activated site-specific recombination in mice. Proc. Natl. Acad. Sci. USA 93, 10887–10890 (1996).
  Article CAS PubMed PubMed Central Google Scholar
• Indra, A.K. et al. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res. 27, 4324–4327 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Claxton, S. et al. Efficient, inducible Cre-recombinase activation in vascular endothelium. Genesis 46, 74–80 (2008).
  Article CAS PubMed Google Scholar
• Sawamiphak, S. et al. Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature 465, 487–491 (2010).
  Article CAS PubMed Google Scholar
• Gerhardt, H. & Betsholtz, C. High-resolution in situ confocal analysis of endothelial cells. in Methods in Endothelial Cell Biology (ed. Augustin, H.G.) 313–323 (Springer-Verlag, 2004).
• Aguilar, E. et al. Chapter 6. Ocular models of angiogenesis. Methods Enzymol. 444, 115–158 (2008).
  Article CAS PubMed Google Scholar
• Gerhardt, H. et al. VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia. J. Cell Biol. 161, 1163–1177 (2003).
  Article CAS PubMed PubMed Central Google Scholar
• Fruttiger, M. et al. PDGF mediates a neuron-astrocyte interaction in the developing retina. Neuron 17, 1117–1131 (1996).
  Article CAS PubMed Google Scholar
• Lobov, I.B. et al. Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting. Proc. Natl. Acad. Sci. USA 104, 3219–3224 (2007).
  Article CAS PubMed PubMed Central Google Scholar
• Laitinen, L. Griffonia simplicifolia lectins bind specifically to endothelial cells and some epithelial cells in mouse tissues. Histochem. J. 19, 225–234 (1987).
  Article CAS PubMed Google Scholar
• Laitinen, L., Virtanen, I. & Saxen, L. Changes in the glycosylation pattern during embryonic development of mouse kidney as revealed with lectin conjugates. J. Histochem. Cytochem. 35, 55–65 (1987).
  Article CAS PubMed Google Scholar
• Alroy, J., Goyal, V. & Warren, C.D. Lectin histochemistry of gangliosidosis. I. Neural tissue in four mammalian species. Acta. Neuropathol. 76, 109–114 (1988).
  Article CAS PubMed Google Scholar
• Grunwald, I.C. et al. Hippocampal plasticity requires postsynaptic ephrinBs. Nat. Neurosci. 7, 33–40 (2004).
  Article CAS PubMed Google Scholar
• Srinivas, S. et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 1, 4 (2001).
  Article CAS PubMed PubMed Central Google Scholar
• Wang, H.U., Chen, Z.F. & Anderson, D.J. Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4. Cell 93, 741–753 (1998).
  Article CAS PubMed Google Scholar
• Baluk, P., Morikawa, S., Haskell, A., Mancuso, M. & McDonald, D.M. Abnormalities of basement membrane on blood vessels and endothelial sprouts in tumors. Am. J. Pathol. 163, 1801–1815 (2003).
  Article PubMed PubMed Central Google Scholar