Intravital multiphoton imaging of immune responses in the mouse ear skin (original) (raw)

• Cahalan, M.D. & Parker, I. Choreography of cell motility and interaction dynamics imaged by two-photon microscopy in lymphoid organs. Annu. Rev. Immunol. 26, 585–626 (2008).
  Article CAS PubMed PubMed Central Google Scholar
• Coombes, J.L. & Robey, E.A. Dynamic imaging of host-pathogen interactions in vivo. Nat. Rev. Immunol. 10, 353–364 (2010).
  Article CAS PubMed Google Scholar
• Germain, R.N., Miller, M.J., Dustin, M.L. & Nussenzweig, M.C. Dynamic imaging of the immune system: progress, pitfalls and promise. Nat. Rev. Immunol. 6, 497–507 (2006).
  Article CAS PubMed Google Scholar
• Hickman, H.D., Bennink, J.R. & Yewdell, J.W. Caught in the act: intravital multiphoton microscopy of host-pathogen interactions. Cell Host Microbe 5, 13–21 (2009).
  Article CAS PubMed PubMed Central Google Scholar
• Ng, L.G., Mrass, P., Kinjyo, I., Reiner, S.L. & Weninger, W. Two-photon imaging of effector T-cell behavior: lessons from a tumor model. Immunol. Rev. 221, 147–162 (2008).
  Article CAS PubMed Google Scholar
• Roediger, B., Ng, L.G., Smith, A.L., de St Groth, B.F. & Weninger, W. Visualizing dendritic cell migration within the skin. Histochem. Cell Biol. 130, 1131–1146 (2008).
  Article CAS PubMed Google Scholar
• Kissenpfennig, A. et al. Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity 22, 643–654 (2005).
  Article CAS PubMed Google Scholar
• Nishibu, A., Ward, B.R., Boes, M. & Takashima, A. Roles for IL-1 and TNFalpha in dynamic behavioral responses of Langerhans cells to topical hapten application. J. Dermatol. Sci. 45, 23–30 (2007).
  Article CAS PubMed Google Scholar
• Nishibu, A. et al. Behavioral responses of epidermal Langerhans cells in situ to local pathological stimuli. J. Invest. Dermatol. 126, 787–796 (2006).
  Article CAS PubMed Google Scholar
• Auffray, C. et al. Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior. Science 317, 666–670 (2007).
  Article CAS PubMed Google Scholar
• Weninger, W. et al. Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels. Immunity 12, 665–676 (2000).
  Article CAS PubMed Google Scholar
• Ng, L.G. et al. Migratory dermal dendritic cells act as rapid sensors of protozoan parasites. PLoS Pathog. 4, e1000222 (2008).
  Article PubMed PubMed Central Google Scholar
• Hoeller, C. et al. In vivo imaging of cutaneous T-cell lymphoma migration to the skin. Cancer Res. 69, 2704–2708 (2009).
  Article CAS PubMed Google Scholar
• Sumaria, N. et al. Cutaneous immunosurveillance by self-renewing dermal {gamma}{delta} T cells. J. Exp. Med. 208, 505–518 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Ng, L.G. et al. Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events. J. Invest. Dermatol. 131, 2058–2068 (2011).
  Article CAS PubMed Google Scholar
• Celli, S., Albert, M.L. & Bousso, P. Visualizing the innate and adaptive immune responses underlying allograft rejection by two-photon microscopy. Nat. Med. 17, 744–749 (2011).
  Article CAS PubMed Google Scholar
• Dudeck, A. et al. Mast cells are key promoters of contact allergy that mediate the adjuvant effects of haptens. Immunity 34, 973–984 (2011).
  Article CAS PubMed Google Scholar
• Matheu, M.P. et al. Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block. Immunity 29, 602–614 (2008).
  Article CAS PubMed PubMed Central Google Scholar
• Peters, N.C. et al. In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies. Science 321, 970–974 (2008).
  Article CAS PubMed PubMed Central Google Scholar
• Graham, D.B. et al. ITAM signaling by Vav family Rho guanine nucleotide exchange factors regulates interstitial transit rates of neutrophils in vivo. PLoS ONE 4, e4652 (2009).
  Article PubMed PubMed Central Google Scholar
• Zinselmeyer, B.H., Lynch, J.N., Zhang, X., Aoshi, T. & Miller, M.J. Video-rate two-photon imaging of mouse footpad—a promising model for studying leukocyte recruitment dynamics during inflammation. Inflamm. Res. 57, 93–96 (2008).
  Article CAS PubMed PubMed Central Google Scholar
• Amornphimoltham, P., Masedunskas, A. & Weigert, R. Intravital microscopy as a tool to study drug delivery in preclinical studies. Adv. Drug Deliv. Rev. 63, 119–128 (2011).
  Article CAS PubMed Google Scholar
• Sen, D., Forrest, L., Kepler, T.B., Parker, I. & Cahalan, M.D. Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1- and Th2-polarizing adjuvants. Proc. Natl. Acad. Sci. USA 107, 8334–8339 (2010).
  Article CAS PubMed Google Scholar
• Hierck, B.P., Iperen, L.V., Gittenberger-De Groot, A.C. & Poelmann, R.E. Modified indirect immunodetection allows study of murine tissue with mouse monoclonal antibodies. J. Histochem. Cytochem. 42, 1499–1502 (1994).
  Article CAS PubMed Google Scholar
• Helft, J. & Merad, M. Isolation of cutaneous dendritic cells. Methods Mol. Biol. 595, 231–233 (2010).
  Article PubMed Google Scholar
• Belkaid, Y., Jouin, H. & Milon, G. A method to recover, enumerate and identify lymphomyeloid cells present in an inflammatory dermal site: a study in laboratory mice. J. Immunol. Methods 199, 5–25 (1996).
  Article CAS PubMed Google Scholar
• Saria, A. & Lundberg, J.M. Evans blue fluorescence: quantitative and morphological evaluation of vascular permeability in animal tissues. J. Neurosci. Methods 8, 41–49 (1983).
  Article CAS PubMed Google Scholar
• Drobizhev, M., Makarov, N.S., Tillo, S.E., Hughes, T.E. & Rebane, A. Two-photon absorption properties of fluorescent proteins. Nat. Methods 8, 393–399 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Davalos, D. et al. ATP mediates rapid microglial response to local brain injury in vivo. Nat. Neurosci. 8, 752–758 (2005).
  Article CAS PubMed Google Scholar
• Kim, J.V. & Dustin, M.L. Innate response to focal necrotic injury inside the blood-brain barrier. J. Immunol. 177, 5269–5277 (2006).
  Article CAS PubMed Google Scholar
• Nimmerjahn, A., Kirchhoff, F. & Helmchen, F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 308, 1314–1318 (2005).
  Article CAS Google Scholar
• Zoumi, A., Yeh, A. & Tromberg, B.J. Imaging cells and extracellular matrix in vivo by using second-harmonic generation and two-photon excited fluorescence. Proc. Natl. Acad. Sci. USA 99, 11014–11019 (2002).
  Article CAS PubMed Google Scholar
• Beltman, J.B., Maree, A.F. & de Boer, R.J. Analysing immune cell migration. Nat. Rev. Immunol. 9, 789–798 (2009).
  Article CAS PubMed Google Scholar
• Muzumdar, M.D., Tasic, B., Miyamichi, K., Li, L. & Luo, L. A global double-fluorescent Cre reporter mouse. Genesis 45, 593–605 (2007).
  Article CAS Google Scholar
• Faust, N., Varas, F., Kelly, L.M., Heck, S. & Graf, T. Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages. Blood 96, 719–726 (2000).
  CAS PubMed Google Scholar
• Townsend, D., Witkop, C.J. Jr. & Mattson, J. Tyrosinase subcellular distribution and kinetic parameters in wild type and C-locus mutant C57BL/6J mice. J. Exp. Zool. 216, 113–119 (1981).
  Article CAS PubMed Google Scholar
• Zhang, J. et al. CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation. Exp. Hematol. 35, 490–499 (2007).
  Article CAS PubMed Google Scholar
• Lindquist, R.L. et al. Visualizing dendritic cell networks in vivo. Nat. Immunol. 5, 1243–1250 (2004).
  Article CAS PubMed Google Scholar
• Jung, S. et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell Biol. 20, 4106–4114 (2000).
  Article CAS PubMed PubMed Central Google Scholar
• Gray, E.E., Suzuki, K. & Cyster, J.G. Cutting edge: identification of a Motile IL-17-Producing {gamma}{delta} T cell population in the dermis. J. Immunol. 186, 6091–6095 (2011).
  Article CAS PubMed PubMed Central Google Scholar
• Unutmaz, D. et al. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse. J. Immunol. 165, 3284–3292 (2000).
  Article CAS PubMed Google Scholar