Palm, W. & de Lange, T. How shelterin protects mammalian telomeres. Annu. Rev. Genet.42, 301–334 (2008). ArticleCASPubMed Google Scholar
Miyoshi, T., Kanoh, J., Saito, M. & Ishikawa, F. Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length. Science320, 1341–1344 (2008). ArticleCASPubMed Google Scholar
Flory, M.R., Carson, A.R., Muller, E.G. & Aebersold, R. An SMC-domain protein in fission yeast links telomeres to the meiotic centrosome. Mol. Cell16, 619–630 (2004). ArticleCASPubMed Google Scholar
Denchi, E.L. & de Lange, T. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. Nature448, 1068–1071 (2007). ArticleCASPubMed Google Scholar
Verdun, R.E. & Karlseder, J. The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell127, 709–720 (2006). ArticleCASPubMed Google Scholar
Moser, B.A. et al. Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres. EMBO J.28, 810–820 (2009). ArticleCASPubMedPubMed Central Google Scholar
Sabourin, M. & Zakian, V.A. ATM-like kinases and regulation of telomerase: lessons from yeast and mammals. Trends Cell Biol.18, 337–346 (2008). ArticleCASPubMedPubMed Central Google Scholar
Naito, T., Matsuura, A. & Ishikawa, F. Circular chromosome formation in a fission yeast mutant defective in two ATM homologues. Nat. Genet.20, 203–206 (1998). ArticleCASPubMed Google Scholar
Moser, B.A., Subramanian, L., Khair, L., Chang, Y.T. & Nakamura, T.M. Fission yeast Tel1ATM and Rad3ATR promote telomere protection and telomerase recruitment. PLoS Genet.5, e1000622 (2009). ArticlePubMedPubMed Central Google Scholar
Beernink, H.T., Miller, K., Deshpande, A., Bucher, P. & Cooper, J.P. Telomere maintenance in fission yeast requires an Est1 ortholog. Curr. Biol.13, 575–580 (2003). ArticleCASPubMed Google Scholar
Fukuhara, N. et al. SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway. Mol. Cell17, 537–547 (2005). ArticleCASPubMed Google Scholar
Cooper, J.P., Nimmo, E.R., Allshire, R.C. & Cech, T.R. Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature385, 744–747 (1997). ArticleCASPubMed Google Scholar
Kanoh, J. & Ishikawa, F. spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast. Curr. Biol.11, 1624–1630 (2001). ArticleCASPubMed Google Scholar
Chikashige, Y. & Hiraoka, Y. Telomere binding of the Rap1 protein is required for meiosis in fission yeast. Curr. Biol.11, 1618–1623 (2001). ArticleCASPubMed Google Scholar
Snow, B.E. et al. Functional conservation of the telomerase protein Est1p in humans. Curr. Biol.13, 698–704 (2003). ArticleCASPubMed Google Scholar
Reichenbach, P. et al. A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed. Curr. Biol.13, 568–574 (2003). ArticleCASPubMed Google Scholar
Redon, S., Reichenbach, P. & Lingner, J. Protein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomerase. Nucleic Acids Res.35, 7011–7022 (2007). ArticleCASPubMedPubMed Central Google Scholar
Nakamura, T.M., Cooper, J.P. & Cech, T.R. Two modes of survival of fission yeast without telomerase. Science282, 493–496 (1998). ArticleCASPubMed Google Scholar
Matsuoka, S. et al. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science316, 1160–1166 (2007). ArticleCASPubMed Google Scholar
Sugiyama, T. et al. SHREC, an effector complex for heterochromatic transcriptional silencing. Cell128, 491–504 (2007). ArticleCASPubMed Google Scholar
Tomaska, L., Willcox, S., Slezakova, J., Nosek, J. & Griffith, J.D. Taz1 binding to a fission yeast model telomere: formation of telomeric loops and higher order structures. J. Biol. Chem.279, 50764–50772 (2004). ArticleCASPubMed Google Scholar
Miller, K.M., Rog, O. & Cooper, J.P. Semi-conservative DNA replication through telomeres requires Taz1. Nature440, 824–828 (2006). ArticleCASPubMed Google Scholar
Hector, R.E. et al. Tel1p preferentially associates with short telomeres to stimulate their elongation. Mol. Cell27, 851–858 (2007). ArticleCASPubMed Google Scholar
Sabourin, M., Tuzon, C.T. & Zakian, V.A. Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. Mol. Cell27, 550–561 (2007). ArticleCASPubMedPubMed Central Google Scholar
Nakamura, T.M., Moser, B.A. & Russell, P. Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. Genetics161, 1437–1452 (2002). CASPubMedPubMed Central Google Scholar
Tseng, S.F., Lin, J.J. & Teng, S.C. The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation. Nucleic Acids Res.34, 6327–6336 (2006). ArticleCASPubMedPubMed Central Google Scholar
Gao, H. et al. Telomerase recruitment in Saccharomyces cerevisiae is not dependent on Tel1-mediated phosphorylation of Cdc13. Genetics186, 1147–1159 (2010). ArticleCASPubMedPubMed Central Google Scholar
Martinez, P. et al. Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes Dev.23, 2060–2075 (2009). ArticleCASPubMedPubMed Central Google Scholar
Xin, H. et al. TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase. Nature445, 559–562 (2007). ArticleCASPubMed Google Scholar
Tejera, A.M. et al. TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice. Dev. Cell18, 775–789 (2010). ArticleCASPubMedPubMed Central Google Scholar
Alfa, C., Fantes, P., Hyams, J., McLoed, M. & Warbrick, E. Experiments with Fission Yeast: A Laboratory Course Manual (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA, 1993).
Amberg, D.C., Burke, D.J. & Strathern, J.N. Methods in Yeast Genetics: A Cold Spring Harbor Laboratory Course Manual (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA, 2005).
Bähler, J. et al. Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe. Yeast14, 943–951 (1998). ArticlePubMed Google Scholar
Krawchuk, M.D. & Wahls, W.P. High-efficiency gene targeting in Schizosaccharomyces pombe using a modular, PCR-based approach with long tracts of flanking homology. Yeast15, 1419–1427 (1999). ArticleCASPubMed Google Scholar
Khair, L., Subramanian, L., Moser, B.A. & Nakamura, T.M. Roles of heterochromatin and telomere proteins in regulation of fission yeast telomere recombination and telomerase recruitment. J. Biol. Chem.285, 5327–5337 (2009). ArticlePubMedPubMed Central Google Scholar
Nimmo, E.R., Pidoux, A.L., Perry, P.E. & Allshire, R.C. Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe. Nature392, 825–828 (1998). ArticleCASPubMed Google Scholar
Lopez-Girona, A. et al. Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast. Proc. Natl. Acad. Sci. USA98, 11289–11294 (2001). ArticleCASPubMedPubMed Central Google Scholar