Expression and transcriptional regulation of functionally distinct Bmf isoforms in B-chronic lymphocytic leukemia cells (original) (raw)

• Cory S, Adams JM . The BCL-2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2002; 2: 647–656.
  Article CAS Google Scholar
• Sattler M, Liang H, Nettesheim D, Meadows RP, Harlan JE, Eberstadt M . Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis. Science 1997; 275: 983–986.
  Article CAS Google Scholar
• O'Connor L, Strasser A, O'Reilly LA, Hausmann G, Adams JM, Cory S . Bim: a novel member of the Bcl-2 family that promotes apoptosis. EMBO J 1998; 17: 384–395.
  Article CAS Google Scholar
• Bouillet P, Strasser A . BH3-only proteins – evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J Cell Sci 2002; 115: 1567–1574.
  CAS PubMed Google Scholar
• Huang DCS, Strasser A . BH3-only proteins – essential initiators of apoptotic cell death. Cell 2000; 103: 839–842.
  Article CAS Google Scholar
• Puthalakath H, Strasser A . Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. Cell Death Differ 2002; 9: 505–512.
  Article CAS Google Scholar
• Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE . Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 2001; 293: 1829–1832.
  Article CAS Google Scholar
• Puthalakath H, Huang DCS, O'Reilly LA, King SM, Strasser A . The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol Cell 1999; 3: 287–296.
  Article CAS Google Scholar
• Mount SM . A catalogue of splice junction sequences. Nucleic Acids Res 1982; 10: 459–472.
  Article CAS Google Scholar
• Collins RJ, Verschuer LA, Harmon BV, Prentice RL, Pope JH, Kerr JF . Spontaneous programmed death (apoptosis) of B-chronic lymphocytic leukaemia cells following their culture in vitro. Br J Haematol 1989; 71: 343–350.
  Article CAS Google Scholar
• Aguilar-Santelises M, Rottenberg ME, Lewin N, Mellstedt H, Jondal M . Bcl-2, Bax and p53 expression in B-CLL in relation to in vitro survival and clinical progression. Int J Cancer 1996; 69: 114–119.
  Article CAS Google Scholar
• Boillet P, Metcalf D, Huang DCS, Tarlinton DM, Kay TWH, Köntgen F . Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 1999; 286: 1735–1738.
  Article Google Scholar
• Bouillet P, Purton JF, Godfrey DI, Zhang LC, Coultas L, Puthalakath H . BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes. Nature 2002; 415: 922–926.
  Article CAS Google Scholar
• Dijkers PF, Medema RH, Lammers J-WJ, Koenderman L, Coffer PJ . Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 2000; 10: 1201–1204.
  Article CAS Google Scholar
• Shinjyo T, Kuribara R, Inukai T, Hosoi H, Kinoshita T, Miyajima A . Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors. Mol Cell Biol 2001; 21: 854–864.
  Article CAS Google Scholar
• Lei K, Davis RJ . JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax dependent apoptosis. Proc Natl Acad Sci 2003; 100: 2432–2437.
  Article CAS Google Scholar
• Villunger A, Scott C, Bouillet P, Strasser A . Essential role for the BH3-only protein Bim, but redundant roles for Bax, Bcl-2 and Bcl-w in the control of granulocyte survival. Blood 2003; 101: 2393–2400.
  Article CAS Google Scholar
• Caligaris-Cappio F, Cignetti A, Granziero L, Ghia P . Chronic lymphocytic leukemia: a model for investigating potential new targets for the therapy of indolent lymphomas. Best Pract Res Clin Haematol 2002; 15: 563–575.
  Article CAS Google Scholar
• Binet JL, Plunkett W, Robertson B, Merle-Beral H, Mentz F, Hoffbrand AV, Panayiotidis P . What does apoptosis mean in CLL? Leukemia Lymphoma 1996; 22 (Suppl 2): 47–52.
  Article Google Scholar
• Consoli U, El-Tounsi I, Sandoval A, Snell V, Kleine HD, Brown W . Differential induction of apoptosis by fludarabine monophosphate in leukemic B and normal T cells in chronic lymphocytic leukemia. Blood 1998; 91: 1742–1748.
  CAS PubMed Google Scholar
• Ricciardi MR, Petrucci MT, Gregorj C, Ariola C, Lemoli RM, Fogli M . Reduced susceptibility to apoptosis correlates with kinetic quiescence in disease progression of chronic lymphocytic leukaemia. Br J Haematol 2001; 113: 391–399.
  Article CAS Google Scholar
• Bouillet P, Cory S, Zhang L-C, Strasser A, Adams JM . Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim. Dev Cell 2001; 1: 645–653.
  Article CAS Google Scholar
• Pepper C, Hoy T, Bentley P . Elevated Bcl-2/Bax are a consistent feature of apoptosis resistance in B-cell chronic lymphocytic leukemia and are correlated with in vivo chemoresistance. Leukemia Lymphoma 1998; 28: 355–361.
  Article CAS Google Scholar
• Kitada S, Andersen J, Akar S, Zapata JM, Takayama S, Krajewski S . Expression of apoptosis-regulating proteins in chronic lymphocytic leukemia: correlations with in vitro and in vivo chemoresponses. Blood 1998; 91: 3379–3389.
  CAS PubMed Google Scholar