Schizophrenia and viral infection during neurodevelopment: a focus on mechanisms (original) (raw)
Walker EF, Diforio D, Baum K . Developmental neuropathology and the precursors of schizophrenia Acta Psychiatr Scand, Suppl 1999 395: 12–19 CAS Google Scholar
Weinberger DR . Implications of normal brain development for the pathogenesis of schizophrenia Arch Gen Psychiatry 1987 44: 660–669 CASPubMed Google Scholar
Murray RM, Jones P, O'Callaghan E, Takei N, Sham P . Genes, viruses and neurodevelopmental schizophrenia J Psychiatr Res 1992 26: 225–235 CASPubMed Google Scholar
Bloom FE . Advancing a neurodevelopmental origin for schizophrenia Arch Gen Psychiatry 1993 50: 224–227 CASPubMed Google Scholar
Gualtieri CT, Adams A, Shen CD, Loiselle D . Minor physical anomalies in alcoholic and schizophrenic adults and hyperactive and autistic children Am J Psychiatry 1982 139: 640–643 CASPubMed Google Scholar
Guy JD, Majorski LV, Wallace CJ, Guy MP . The incidence of minor physical anomalies in adult male schizophrenics Schizophr Bull 1983 9: 571–582 CASPubMed Google Scholar
Arnold SE . Neurodevelopmental abnormalities in schizophrenia: insights from neuropathology Dev Psychopath 1999 11: 439–456 CAS Google Scholar
Jakob H, Beckmann H . Prenatal developmental disturbances in the limbic allocortex in schizophrenics J Neural Transm 1986 65: 303–326 CASPubMed Google Scholar
Conrad AJ, Scheibel AB . Schizophrenia and the hippocampus: the embryological hypothesis extended Schizophr Bull 1987 13: 577–587 CASPubMed Google Scholar
Kovelman JA, Scheibel AB . A neurohistological correlate of schizophrenia Biol Psychiatry 1984 19: 1601–1621 CASPubMed Google Scholar
Barbeau D, Liang JJ, Robitalille Y, Quirion R, Srivastava LK . Decreased expression of the embryonic form of the neural cell adhesion molecule in schizophrenic brains Proc Natl Acad Sci USA 1995 92: 2785–2789 CASPubMedPubMed Central Google Scholar
Roberts GW, Colter N, Lofthouse R, Bogerts B, Zech M, Crow TJ . Gliosis in schizophrenia: a survey Biol Psychiatry 1986 21: 1043–1050 CASPubMed Google Scholar
Poltorak M, Wright R, Hemperly JJ, Torrey EF, Issa F, Wyatt RJ et al. Monozygotic twins discordant for schizophrenia are discordant for N-CAM and L1 in CSF Brain Res 1997 751: 152–154 CASPubMed Google Scholar
van Kammen DP, Poltorak M, Kelley ME, Yao JK, Gurklis JA, Peters JL et al. Further studies of elevated cerebrospinal fluid neuronal cell adhesion molecule in schizophrenia Biol Psychiatry 1998 43: 680–686 CASPubMed Google Scholar
Petronis A, Paterson AD, Kennedy JL . Schizophrenia: an epigenetic puzzle Schizophr Bull 1999 25: 639–655 CASPubMed Google Scholar
Tsuang M . Schizophrenia: genes and environment Biol Psychiatry 2000 47: 210–220 CASPubMed Google Scholar
Torrey EF, Yolken RH . Familial and genetic mechanisms in schizophrenia Brain Res Rev 1999 31: 113–117 Google Scholar
Cardno AG, Marshall EJ, Coid B, Macdonald AM, Ribchester TR, Davies NJ et al. Heritability estimates for psychotic disorders: the Maudsley twin psychosis series Arch Gen Psychiatry 1999 56: 162–168 CASPubMed Google Scholar
Torrey EF . Are we overestimating the genetic contribution to schizophrenia? Schizophr Bull 1992 18: 159–170 CASPubMed Google Scholar
Suddath RL, Christison GW, Torrey FE, Casanova MF, Weinberger DR . Anatomical abnormalities in the brains of monozygotic twins discordant for schizophrenia New Engl J Med 1990 322: 789–794 CASPubMed Google Scholar
Robertson EG, Neer KJ . Placental injection studies in twin gestation Am J Obstet Gynecol 1983 147: 170–174 CASPubMed Google Scholar
Davis JO, Phelps JA, Bracha HS . Prenatal development of monozygotic twins and concordance for schizophrenia [published erratum appears in Schizophr Bull 1995; 21: 539] Schizophr Bull 1995 21: 357–366 CASPubMed Google Scholar
Squires RF . How a poliovirus might cause schizophrenia: a commentary on Eagles’ hypothesis Neurochem Res 1997 22: 647–656 CASPubMed Google Scholar
Ahlfors K, Ivarsson SA, Nilsson H . On the unpredictable development of congenital cytomegalovirus infection. A study in twins Early Hum Dev 1988 18: 125–135 CASPubMed Google Scholar
Machin GA . Some causes of genotypic and phenotypic discordance in monozygotic twin pairs Am J Med Genet 1996 61: 216–228 CASPubMed Google Scholar
DeLisi LE . Critical overview of current approaches to genetic mechanisms in schizophrenia research Brain Res Rev 2000 31: 187–192 CASPubMed Google Scholar
Torrey EF, Peterson MR . The viral hypothesis of schizophrenia Schizophr Bull 1976 2: 136–146 CASPubMed Google Scholar
O'Reilly RL, Singh SM . Retroviruses and schizophrenia revisited Am J Med Genet 1996 67: 19–24 CASPubMed Google Scholar
Kirch DG . Infection and autoimmunity as etiologic factors in schizophrenia: a review and reappraisal Schizophr Bull 1993 19: 355–370 CASPubMed Google Scholar
Brown AS, Cohen P, Greenwald S, Susser E . Nonaffective psychosis after prenatal exposure to rubella Am J Psychiatry 2000 157: 438–443 CASPubMed Google Scholar
Brown AS, Schaefer CA, Wyatt RJ, Goetz R, Begg MD, Gorman JM et al. Maternal exposure to respiratory infections and adult schizophrenia spectrum disorders: a prospective birth cohort study Schizophr Bull 2000 26: 287–295 CASPubMed Google Scholar
Mednick SA, Huttunen MO, Machon RA . Prenatal influenza infections and adult schizophrenia Schizophr Bull 1994 20: 263–267 CASPubMed Google Scholar
O'Callaghan E, Sham PC, Takei N, Murray G, Glover G, Hare EH et al. The relationship of schizophrenic births to 16 infectious diseases Br J Psychiatry 1994 165: 353–356 CASPubMed Google Scholar
Rantakallio P, Jones P, Moring J, Von Wendt L . Association between central nervous system infections during childhood and adult onset schizophrenia and other psychoses: a 28-year follow-up Int J Epidemiol 1997 26: 837–843 CASPubMed Google Scholar
Salvatore M, Morzunov S, Schwemmle M, Lipkin WI, Bunney WE, Cotman CW et al. Borna disease virus in brains of North American and European people with schizophrenia and bipolar disorder Lancet 1997 349: 1813–1814 CASPubMed Google Scholar
Suvisaari J, Haukka J, Tanskanen A, Hovi T, Lonnqvist J . Association between prenatal exposure to poliovirus infection and adult schizophrenia Am J Psychiatry 1999 156: 1100–1102 CASPubMed Google Scholar
Nakamura Y, Takahashi H, Shoya Y, Nakaya T, Watanabe M, Tomonaga K et al. Isolation of Borna disease virus from human brain tissue J Virol 2000 74: 4601–4611 CASPubMedPubMed Central Google Scholar
Bode L, Zimmermann W, Ferszt R, Steinbach F, Ludwig H . Borna disease virus genome transcribed and expressed in psychiatric patients Nat Med 1995 1: 232–236 CASPubMed Google Scholar
Bode L, Durrwald R, Rantam FA, Ferszt R, Ludwig H . First isolates of infectious human Borna disease virus from patients with mood disorders Mol Psychiatry 1996 1: 200–212 CASPubMed Google Scholar
Bode L, Ludwig H . Clinical similarities and close genetic relationship of human and animal Borna disease virus Arch Virol-Suppl 1997 13: 167–182 CASPubMed Google Scholar
Rott R, Herzog S, Fleischer B, Winokur A, Amsterdam J, Dyson W et al. Detection of serum antibodies to Borna disease virus in patients with psychiatric disorders Science 1985 228: 755–756 CASPubMed Google Scholar
Ludwig H, Bode L . The neuropathogenesis of Borna disease virus infections Intervirology 1997 40: 185–197 CASPubMed Google Scholar
Volpe JJ . Neurology of the Newborn WB Sanders Company: Philadelphia 1995 pp?675–729 Google Scholar
Torrey EF, Yolken RH . At issue: is household crowding a risk factor for schizophrenia and bipolar disorder? Schizophr Bull 1998 24: 321–324 CASPubMed Google Scholar
McCreadie RG . The Nithsdale Schizophrenia Surveys 16. Breast-feeding and schizophrenia: preliminary results and hypotheses Br J Psychiatry 1997 170: 334–337 CASPubMed Google Scholar
Abel L, Dessein AJ . The impact of host genetics on susceptibility to human infectious diseases Curr Opin Immunol 1997 9: 509–516 CASPubMed Google Scholar
DeLisi LE . Is there a viral or immune dysfunction etiology to schizophrenia? Re-evaluation a decade later Schizophr Res 1996 22: 1–4 CASPubMed Google Scholar
Andreasen NC, Carpenter WT Jr . Diagnosis and classification of schizophrenia Schizophr Bull 1993 19: 199–214 CASPubMed Google Scholar
Crow TJ . Neurohumoural and structural changes in schizophrenia: two dimensions of pathology Prog Brain Res 1982 55: 407–417 CASPubMed Google Scholar
Knoll JLT, Garver DL, Ramberg JE, Kingsbury SJ, Croissant D, McDermott B . Heterogeneity of the psychoses: is there a neurodegenerative psychosis? Schizophr Bull 1998 24: 365–379 PubMed Google Scholar
Stevens JR . Anatomy of schizophrenia revisited Schizophr Bull 1997 23: 373–383 CASPubMed Google Scholar
Nahmias AJ, Kourtis AP . The great balancing acts. The pregnant woman, placenta, fetus, and infectious agents Clin Perinatol 1997 24: 497–521 CASPubMed Google Scholar
Hall AJ, Peckham CS . Infections in childhood and pregnancy as a cause of adult disease—methods and examples Br Med Bull 1997 53: 10–23 CASPubMed Google Scholar
Uno M, Takano T, Yamano T, Shimada M . Age-dependent susceptibility in mumps-associated hydrocephalus: neuropathologic features and brain barriers Acta Neuropathol (Berl) 1997 94: 207–215 CAS Google Scholar
Ahlfors K, Ivarsson SA, Harris S . Report on a long-term study of maternal and congenital cytomegalovirus infection in Sweden. Review of prospective studies available in the literature Scand J Infect Dis 1999 31: 443–457 CASPubMed Google Scholar
Johnson RT . Viral Infections of the Nervous System, 2nd edn Lippincott-Raven: Philadelphia 1998 Google Scholar
Lennette EH . Problems in the diagnostic laboratory with respect to poliomyelitis. In: Conference IP (ed) Poliomyelitis Lippincott: Philadelphia 1958 pp?377–388 Google Scholar
Julien J, Leparc-Goffart I, Lina B, Fuchs F, Foray S, Janatova I et al. Postpolio syndrome: poliovirus persistence is involved in the pathogenesis J Neurol 1999 246: 472–476 CASPubMed Google Scholar
Leon-Monzon ME, Dalakas MC . Detection of poliovirus antibodies and poliovirus genome in patients with the post-polio syndrome Ann N Y Acad Sci 1995 753: 208–218 CASPubMed Google Scholar
Jacobs BC, Rothbarth PH, van der Meche FG, Herbrink P, Schmitz PI, de Klerk MA et al. The spectrum of antecedent infections in Guillain–Barre syndrome: a case-control study Neurology 1998 51: 1110–1105 CASPubMed Google Scholar
Illa I, Ortiz N, Gallard E, Juarez C, Grau JM, Dalakas MC . Acute axonal Guillain-Barre syndrome with IgG antibodies against motor axons following parenteral gangliosides Ann Neurol 1995 38: 218–224 CASPubMed Google Scholar
Hoek HW, Brown AS, Susser E . The Dutch Famine and schizophrenia spectrum disorders Soc Psychiatr Psychiatr Epidemiol 1998 33: 373–379 CAS Google Scholar
Cannon TD . On the nature and mechanisms of obstetric influences in schizophrenia: a review and synthesis of epidemiologic studies Int Rev Psychiatry 1997 9: 387–397 Google Scholar
DeLisi LE, Goodman S, Neckers LM, Wyatt RJ . An analysis of lymphocyte subpopulations in schizophrenic patients Biol Psychiatry 1982 17: 1003–1009 CASPubMed Google Scholar
Printz DJ, Strauss DH, Goetz R, Sadiq S, Malaspina D, Krolewski J et al. Elevation of CD5+ B lymphocytes in schizophrenia Biol Psychiatry 1999 46: 110–118 CASPubMed Google Scholar
McAllister CG, Rapaport MH, Pickar D, Podruchny TA, Christison G, Alphs LD et al. Increased numbers of CD5+ B lymphocytes in schizophrenic patients Arch Gen Psychiatry 1989 46: 890–894 CASPubMed Google Scholar
Casali P, Burastero SE, Nakamura M, Inghirami G, Notkins AL . Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset Science 1987 236: 77–81 CASPubMed Google Scholar
Ganguli R, Brar JS, Chengappa KNR, Yang ZW, Nimgaonkar VL, Rabin BS . Autoimmunity in schizophrenia: a review of recent findings Ann Med 1993 25: 489–496 CASPubMed Google Scholar
Henneberg AE, Horter S, Ruffert S . Increased prevalence of antibrain antibodies in the sera from schizophrenic patients Schizophr Res 1994 14: 15–22 CASPubMed Google Scholar
Yang ZW, Chengappa KNR, Shurin G, Brar JS, Rabin BS, Gubbi AV et al. An association between anti-hippocampal antibody concentration and lymphocyte production of IL-2 in patients with schizophrenia Psychol Med 1994 24: 449–455 CASPubMed Google Scholar
Oldstone MB . Molecular mimicry and immune-mediated diseases FASEB J 1998 12: 1255–1265 CASPubMed Google Scholar
Fabry Z, Raine CS, Hart MN . Nervous tissue as an immune compartment: the dialect of the immune response in the CNS Immunol Today 1994 15: 218–224 CASPubMed Google Scholar
Goldstein GW, Robertson P, Betz AL . Update on the role of the blood-brain barrier in damage to immature brain Pediatrics 1988 81: 732–734 CASPubMed Google Scholar
Bauer K, Kornhuber J . Blood-cerebrospinal fluid barrier in schizophrenic patients Eur Arch Psychiatr Neurol Sci 1987 236: 257–259 CAS Google Scholar
Kirch DG, Alexander RC, Suddath RL, Papadopoulos NM, Kaufmann CA, Daniel DG et al. Blood-CSF barrier permeability and central nervous system immunoglobulin G in schizophrenia J Neural Transm–Gen Sect 1992 89: 219–232 CASPubMed Google Scholar
Arnason BGW . Autoimmune diseases of the central and peripheral nervous systems. In: Rose NR, Mackay IR (eds) The Autoimmune Diseases Academic Press: San Diego 1998 pp?571–602 Google Scholar
Jeffery KJ, Usuku K, Hall SE, Matsumoto W, Taylor GP, Procter J et al. HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy Proc Natl Acad Sci USA 1999 96: 3848–3853 CASPubMedPubMed Central Google Scholar
Usuku K, Sonoda S, Osame M, Yashiki S, Takahashi K, Matsumoto M et al. HLA haplotype-linked high immune responsiveness against HTLV-I in HTLV-I-associated myelopathy: comparison with adult T-cell leukemia/lymphoma Ann Neurol 1988 23 Suppl: S143–S150 CASPubMed Google Scholar
Wright P, Gill M, Murray RM . Schizophrenia: genetics and the maternal immune response to viral infection Am J Med Genet 1993 48: 40–46 CASPubMed Google Scholar
Hofman FM, Danilovs JA, Taylor CR . HLA-DR (Ia)-positive dendritic-like cells in human fetal nonlymphoid tissues Transplantation 1984 37: 590–594 CASPubMed Google Scholar
Oliver AM, Sewell HF, Abramovich DR, Thomson AW . The distribution and differential expression of MHC class II antigens (HLA-DR, DP, and DQ) in human fetal adrenal, pancreas, thyroid, and gut Transplant Proc 1989 21: 651–652 CASPubMed Google Scholar
Nawa H, Takahashi M, Patterson PH . Cytokine and growth factor involvement in schizophrenia—support for the developmental model Mol Psychiatry 2000 5: 594–603 CASPubMed Google Scholar
Urakubo A, Jarskog LF, Lieberman JA, Gilmore JH . Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid, and fetal brain Schizophr Res 2001 47: 27–36 CASPubMed Google Scholar
Nath A . Pathobiology of human immunodeficiency virus dementia Semin Neurol 1999 19: 113–127 CASPubMed Google Scholar
Tamminga CA, Thaker GK, Buchanan R, Kirkpatrick B, Alphs LD, Chase TN et al. Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome Arch Gen Psychiatry 1992 49: 522–530 CASPubMed Google Scholar
Harrison PJ . The neuropathology of schizophrenia. A critical review of the data and their interpretation Brain 1999 122: 593–624 PubMed Google Scholar
Bogerts B . Recent advances in the neuropathology of schizophrenia Schizophr Bull 1993 19: 431–445 CASPubMed Google Scholar
Benes FM . Emerging principles of altered neural circuitry in schizophrenia Brain Res Brain Res Rev 2000 31: 251–269 CASPubMed Google Scholar
Gosztonyi G (ed) . The mechanism of neuronal damage in virus infections of the nervous system Curr Top Microbiol Immunol 2001 253: 1–273 PubMed Google Scholar
Tyler KL, Fields BN . Pathogenesis of viral infections. In: Fields BN, Knipe DM, Howley PM (eds) Fields Virology Lippincott-Raven: Philadelphia 1996 pp?173–218 Google Scholar
Cotter D, Takei N, Farrell M, Sham P, Quinn P, Larkin C et al. Does prenatal exposure to influenza in mice induce pyramidal cell disarray in the dorsal hippocampus? Schizophr Res 1995 16: 233–241 CASPubMed Google Scholar
Fatemi SH, Emamian ES, Kist D, Sidwell RW, Nakajima K, Akhter P et al. Defective corticogenesis and reduction in Reelin immunoreactivity in cortex and hippocampus of prenatally infected neonatal mice Mol Psychiatry 1999 4: 145–154 CASPubMed Google Scholar
Shinmura Y, Kosugi I, Aiba-Masago S, Baba S, Yong LR, Tsutsui Y . Disordered migration and loss of virus-infected neuronal cells in developing mouse brains infected with murine cytomegalovirus Acta Neuropathol (Berl) 1997 93: 551–557 CAS Google Scholar
Rubin SA, Pletnikov M, Carbone KM . Comparison of the neurovirulence of a vaccine and a wild-type mumps virus strain in the developing rat brain J Virol 1998 72: 8037–8042 CASPubMedPubMed Central Google Scholar
Ramirez JC, Fairen A, Almendral JM . Parvovirus minute virus of mice strain i multiplication and pathogenesis in the newborn mouse brain are restricted to proliferative areas and to migratory cerebellar young neurons J Virol 1996 70: 8109–8116 CASPubMedPubMed Central Google Scholar
Impagnatiello F, Guidotti AR, Pesold C, Dwivedi Y, Caruncho H, Pisu MG et al. A decrease of reelin expression as a putative vulnerability factor in schizophrenia Proc Natl Acad Sci USA 1998 95: 15718–15723 CASPubMedPubMed Central Google Scholar
Reynolds GP . Neurotransmitter systems in schizophrenia Int Rev Neurobiol 1995 38: 305–339 CASPubMed Google Scholar
Duncan GE, Sheitman BB, Lieberman JA . An integrated view of pathophysiological models of schizophrenia Brain Res Brain Res Rev 1999 29: 250–264 CASPubMed Google Scholar
Lycke E, Roos BE . Virus infections in infant mice causing persistent impairment of turnover of brain catecholamines J Neurol Sci 1975 26: 49–60 CASPubMed Google Scholar
Crnic LS . Behavioral consequences of virus infections. In: Ader R, Felton DL, Cohen N (eds) Psychoneuroimmunology, 2nd edn Academic Press: San Diego 1991 pp?749–768 Google Scholar
Mohammed AH, Norrby E, Kristensson K . Viruses and behavioural changes: a review of clinical and experimental findings Rev Neurosci 1993 4: 267–286 CASPubMed Google Scholar
Dittrich W, Bode L, Ludwig H, Kao M, Schneider K . Learning deficiencies in Borna disease virus-infected but clinically healthy rats Biol Psychiatry 1989 26: 818–828 CASPubMed Google Scholar
Pletnikov MV, Rubin SA, Schwartz GJ, Carbone KM, Moran TH . Effects of neonatal rat Borna disease virus (BDV) infection on the postnatal development of the brain monoaminergic systems Brain Res Dev Brain Res 2000 119: 179–185 CASPubMed Google Scholar
Solbrig MV, Koob GF, Fallon JH, Reid S, Lipkin WI . Prefrontal cortex dysfunction in Borna disease virus (BDV)-infected rats Biol Psychiatry 1996 40: 629–636 CASPubMed Google Scholar
Carlsson A . The current status of the dopamine hypothesis of schizophrenia Neuropsychopharmacology 1988 1: 179–186 CASPubMed Google Scholar
Reynolds GP, Czudek C, Andrews HB . Deficit and hemispheric asymmetry of GABA uptake sites in the hippocampus in schizophrenia Biol Psychiatry 1990 27: 1038–1044 CASPubMed Google Scholar
Simpson MD, Slater P, Deakin JF, Royston MC, Skan WJ . Reduced GABA uptake sites in the temporal lobe in schizophrenia Neurosci Lett 1989 107: 211–215 CASPubMed Google Scholar
Lewis DA, Pierri JN, Volk DW, Melchitzky DS, Woo TU . Altered GABA neurotransmission and prefrontal cortical dysfunction in schizophrenia Biol Psychiatry 1999 46: 616–626 CASPubMed Google Scholar
Sherman AD, Davidson AT, Baruah S, Hegwood TS, Waziri R . Evidence of glutamatergic deficiency in schizophrenia Neurosci Lett 1991 121: 77–80 CASPubMed Google Scholar
Akbarian S, Kim JJ, Potkin SG, Hagman JO, Tafazzoli A, Bunney WE Jr et al. Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics Arch Gen Psychiatry 1995 52: 258–266; discussion 67–78 Google Scholar
Toru M, Watanabe S, Shibuya H, Nishikawa T, Noda K, Mitsushio H et al. Neurotransmitters, receptors and neuropeptides in post-mortem brains of chronic schizophrenic patients Acta Psychiatr Scand 1988 78: 121–137 CASPubMed Google Scholar
Kutay FZ, Pogun S, Hariri NI, Peker G, Erlacin S . Free amino acid level determinations in normal and schizophrenic brain Prog Neuro-Psychopharmacol Biol Psychiatry 1989 13: 119–126 CAS Google Scholar
Benes FM, McSparren J, Bird ED, SanGiovanni JP, Vincent SL . Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients Arch Gen Psychiatry 1991 48: 996–1001 CASPubMed Google Scholar
Benes FM, Kwok EW, Vincent SL, Todtenkopf MS . A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives Biol Psychiatry 1998 44: 88–97 CASPubMed Google Scholar
Nemeroff CB, Youngblood WW, Manberg PJ, Prange AJ Jr, Kizer JS . Regional brain concentrations of neuropeptides in Huntington's chorea and schizophrenia Science 1983 221: 972–975 CASPubMed Google Scholar
Bachus SE, Hyde TM, Herman MM, Egan MF, Kleinman JE . Abnormal cholecystokinin mRNA levels in entorhinal cortex of schizophrenics J Psychiatr Res 1997 31: 233–256 CASPubMed Google Scholar
Gabriel SM, Davidson M, Haroutunian V, Powchik P, Bierer LM, Purohit DP et al. Neuropeptide deficits in schizophrenia vs Alzheimer's disease cerebral cortex Biol Psychiatry 1996 39: 82–91 CASPubMed Google Scholar
Powchik P, Davidson M, Haroutunian V, Gabriel SM, Purohit DP, Perl DP et al. Postmortem studies in schizophrenia Schizophr Bull 1998 24: 325–341 CASPubMed Google Scholar
Roberts GW, Ferrier IN, Lee Y, Crow TJ, Johnstone EC, Owens DG et al. Peptides, the limbic lobe and schizophrenia Brain Res 1983 288: 199–211 CASPubMed Google Scholar
Virgo L, Humphries C, Mortimer A, Barnes T, Hirsch S, de Belleroche J . Cholecystokinin messenger RNA deficit in frontal and temporal cerebral cortex in schizophrenia Biol Psychiatry 1995 37: 694–701 CASPubMed Google Scholar
Simpson MD, Slater P, Deakin JF . Comparison of glutamate and gamma-aminobutyric acid uptake binding sites in frontal and temporal lobes in schizophrenia Biol Psychiatry 1998 44: 423–427 CASPubMed Google Scholar
Tsai G, Passani LA, Slusher BS, Carter R, Baer L, Kleinman JE et al. Abnormal excitatory neurotransmitter metabolism in schizophrenic brains Arch Gen Psychiatry 1995 52: 829–836 CASPubMed Google Scholar
Kim JS, Kornhuber HH, Schmid-Burgk W, Holzmuller B . Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia Neurosci Lett 1980 20: 379–382 CASPubMed Google Scholar
Harrison PJ, Eastwood SL . Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia [published erratum appears in Lancet 1999; 353: 154] Lancet 1998 352: 1669–1673 CASPubMed Google Scholar
Deakin JF, Slater P, Simpson MD, Gilchrist AC, Skan WJ, Royston MC et al. Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia J Neurochem 1989 52: 1781–1786 CASPubMed Google Scholar
Benes FM, Sorensen I, Vincent SL, Bird ED, Sathi M . Increased density of glutamate-immunoreactive vertical processes in superficial laminae in cingulate cortex of schizophrenic brain Cereb Cortex 1992 2: 503–512 CASPubMed Google Scholar
Goff DC . What is the role of glutamate in schizophrenia? Harv Ment Health Lett 1999 15: 8 CASPubMed Google Scholar
Meador-Woodruff JH, Healy DJ . Glutamate receptor expression in schizophrenic brain Brain Res Brain Res Rev 2000 31: 288–294 CASPubMed Google Scholar
Keshavan MS . Development, disease and degeneration in schizophrenia: a unitary pathophysiological model J Psychiatr Res 1999 33: 513–521 CASPubMed Google Scholar
Farber NB, Newcomer JW, Olney JW . The glutamate synapse in neuropsychiatric disorders. Focus on schizophrenia and Alzheimer's disease Prog Brain Res 1998 116: 421–437 CASPubMed Google Scholar
Cowell PE, Fitch RH, Denenberg VH . Laterality in animals: relevance to schizophrenia Schizophr Bull 1999 25: 41–62 CASPubMed Google Scholar
Gruzelier JH . Functional neuropsychophysiological asymmetry in schizophrenia: a review and reorientation Schizophr Bull 1999 25: 91–120 CASPubMed Google Scholar
Crow TJ, Ball J, Bloom SR, Brown R, Bruton CJ, Colter N et al. Schizophrenia as an anomaly of development of cerebral asymmetry. A postmortem study and a proposal concerning the genetic basis of the disease Arch Gen Psychiatry 1989 46: 1145–1150 CASPubMed Google Scholar
Jeste DV, Lohr JB . Hippocampal pathologic findings in schizophrenia. A morphometric study Arch Gen Psychiatry 1989 46: 1019–1024 CASPubMed Google Scholar
Zaidel DW, Esiri MM, Harrison PJ . The hippocampus in schizophrenia: lateralized increase in neuronal density and altered cytoarchitectural asymmetry Psychol Med 1997 27: 703–713 CASPubMed Google Scholar
Johnstone EC, Owens DG, Crow TJ, Frith CD, Alexandropolis K, Bydder G et al. Temporal lobe structure as determined by nuclear magnetic resonance in schizophrenia and bipolar affective disorder J Neurol Neurosurg Psychiatr 1989 52: 736–741 CAS Google Scholar
Barta PE, Pearlson GD, Powers RE, Richards SS, Tune LE . Auditory hallucinations and smaller superior temporal gyral volume in schizophrenia Am J Psychiatry 1990 147: 1457–1462 CASPubMed Google Scholar
Calabrese G, Deicken RF, Fein G, Merrin EL, Schoenfeld F, Weiner MW . 31Phosphorus magnetic resonance spectroscopy of the temporal lobes in schizophrenia Biol Psychiatry 1992 32: 26–32 CASPubMed Google Scholar
Gur RE, Resnick SM, Gur RC . Laterality and frontality of cerebral blood flow and metabolism in schizophrenia: relationship to symptom specificity Psychiatry Res 1989 27: 325–334 CASPubMed Google Scholar
Neveu PJ . Brain lateralization and immunomodulation Int J Neurosci 1993 70: 135–143 CASPubMed Google Scholar
Vita A, Giobbio GM, Dieci M, Garbarini M, Morganti C, Comazzi M et al. Stability of cerebral ventricular size from the appearance of the first psychotic symptoms to the later diagnosis of schizophrenia Biol Psychiatry 1994 35: 960–962 CASPubMed Google Scholar
Feinberg I . Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence? J Psychiatr Res 1982 17: 319–334 PubMed Google Scholar
Woods BT . Is schizophrenia a progressive neurodevelopmental disorder? Toward a unitary pathogenetic mechanism Am J Psychiatry 1998 155: 1661–1670 CASPubMed Google Scholar
Degreef G, Ashtari M, Bogerts B, Bilder RM, Jody DN, Alvir JMJ et al. Volumes of ventricular system subdivisions measured from magnetic resonance images in first-episode schizophrenic patients Arch Gen Psychiatry 1992 49: 531–537 CASPubMed Google Scholar
DeLisi LE, Hoff AL, Schwartz JE, Shields GW, Halthore SN, Gupta SM et al. Brain morphology in first-episode schizophrenic-like psychotic patients: a quantitative magnetic resonance imaging study Biol Psychiatry 1991 29: 159–175 CASPubMed Google Scholar
Rapoport JL, Giedd J, Kumra S, Jacobsen L, Smith A, Lee P et al. Childhood-onset schizophrenia. Progressive ventricular change during adolescence Arch Gen Psychiatry 1997 54: 897–903 CASPubMed Google Scholar
Woods BT, Yurgelun-Todd D, Benes FM, Frankenburg FR, Pope HG Jr, McSparren J . Progressive ventricular enlargement in schizophrenia: comparison to bipolar affective disorder and correlation with clinical course Biol Psychiatry 1990 27: 341–352 CASPubMed Google Scholar
Lieberman JA . Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective Biol Psychiatry 1999 46: 729–739 CASPubMed Google Scholar
Lipska BK, Weinberger DR . To model a psychiatric disorder in animals: schizophrenia as a reality test Neuropsychopharmacology 2000 23: 223–239 CASPubMed Google Scholar
Lyon M, McClure WO . Investigations of fetal development models for prenatal drug exposure and schizophrenia. Prenatal d-amphetamine effects upon early and late juvenile behavior in the rat Psychopharmacology (Berl) 1994 116: 226–236 CAS Google Scholar
Schwarzkopf SB, Mitra T, Bruno JP . Sensory gating in rats depleted of dopamine as neonates: potential relevance to findings in schizophrenic patients Biol Psychiatry 1992 31: 759–773 CASPubMed Google Scholar
Talamini LM, Koch T, Luiten PG, Koolhaas JM, Korf J . Interruptions of early cortical development affect limbic association areas and social behaviour in rats; possible relevance for neurodevelopmental disorders Brain Res 1999 847: 105–120 CASPubMed Google Scholar
Johnston MV, Barks J, Greenamyre T, Silverstein F . Use of toxins to disrupt neurotransmitter circuitry in the developing brain Prog Brain Res 1988 73: 425–446 CASPubMed Google Scholar
Lipska BK, Weinberger DR . Subchronic treatment with haloperidol and clozapine in rats with neonatal excitotoxic hippocampal damage Neuropsychopharmacology 1994 10: 199–205 CASPubMed Google Scholar
Lillrank SM, Lipska BK, Weinberger DR . Neurodevelopmental animal models of schizophrenia Clin Neurosci 1995 3: 98–104 CASPubMed Google Scholar
Black MD, Selk DE, Hitchcock JM, Wettstein JG, Sorensen SM . On the effect of neonatal nitric oxide synthase inhibition in rats: a potential neurodevelopmental model of schizophrenia Neuropharmacology 1999 38: 1299–1306 CASPubMed Google Scholar
Brake WG, Boksa P, Gratton A . Effects of perinatal anoxia on the acute locomotor response to repeated amphetamine administration in adult rats Psychopharmacology (Berl) 1997 133: 389–395 CAS Google Scholar
Morgane PJ, Austin-LaFrance R, Bronzino J, Tonkiss J, Diaz-Cintra S, Cintra L et al. Prenatal malnutrition and development of the brain Neurosci Biobehav Rev 1993 17: 91–128 CASPubMed Google Scholar
Beauregard M, Bachevalier J . Neonatal insult to the hippocampal region and schizophrenia: a review and a putative animal model Can J Psychiatry–Rev Can Psychiatrie 1996 41: 446–456 CAS Google Scholar
Geyer MA, Wilkinson LS, Humby T, Robbins TW . Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia Biol Psychiatry 1993 34: 361–372 CASPubMed Google Scholar
Engel JA, Zhang J, Bergstrom T, Conradi N, Forkstam C, Liljeroth A et al. Neonatal herpes simplex virus type 1 brain infection affects the development of sensorimotor gating in rats Brain Res 2000 863: 233–240 CASPubMed Google Scholar
McFarland DJ, Hotchin J . Host genetics and the behavioral sequelae to herpes encephalitis in mice Physiol Behav 1983 30: 881–884 CASPubMed Google Scholar
Hotchin J, Seegal R . Virus-induced behavioral alteration of mice Science 1977 196: 671–674 CASPubMed Google Scholar
de la Torre JC, Mallory M, Brot M, Gold L, Koob G, Oldstone MBA et al. Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells Virology 1996 220: 508–515 CASPubMed Google Scholar
Pletnikov MV, Rubin SA, Vasudevan K, Moran TH, Carbone KM . Developmental brain injury associated with abnormal play behavior in neonatally Borna disease virus-infected Lewis rats: a model of autism Behav Brain Res 1999 100: 43–50 CASPubMed Google Scholar
Hornig M, Weissenbock H, Horscroft N, Lipkin WI . An infection-based model of neurodevelopmental damage Proc Natl Acad Sci USA 1999 96: 12102–12107 CASPubMedPubMed Central Google Scholar
Humphrey T . The development of the human hippocampal fissure J Anatomy 1967 101: 655–676 CAS Google Scholar
Pearce BD, Steffensen SC, Paoletti AD, Henriksen SJ, Buchmeier MJ . Persistent dentate granule cell hyperexcitability after neonatal infection with lymphocytic choriomeningitis virus J Neurosci 1996 16: 220–228 CASPubMedPubMed Central Google Scholar
Pearce BD, Valadi NM, Po CL, Miller AH . Viral infection of developing GABAergic neurons in a model of hippocampal disinhibition Neuroreport 2000 11: 2433–2439 CASPubMed Google Scholar
Monjan AA, Cole GA, Nathanson N . Pathogenesis of LCMV disease in the rat. In: Lehmann-Grube F (ed) Lymphocytic Choriomeningitis Virus and Other Arenaviruses Springer: Berlin, Heidelberg, & New York 1973 pp?195–206 Google Scholar
Altman J, Bayer SA . Mosaic organization of the hippocampal neuroepithelium and the multiple germinal sources of dentate granule cells J Comp Neurol 1990 301: 325–342 CASPubMed Google Scholar
Baldridge JR, Pearce BD, Parekh BS, Buchmeier MJ . Teratogenic effects of neonatal arenavirus infection on the developing rat cerebellum are abrogated by passive immunotherapy Virology 1993 197: 669–677 CASPubMed Google Scholar
Dupuy-Davies S, Houser CR . Evidence for changing positions of GABA neurons in the developing rat dentate gyrus Hippocampus 1999 9: 186–199 CASPubMed Google Scholar
Bergmann I, Nitsch R, Frotscher M . Area-specific morphological and neurochemical maturation of non-pyramidal neurons in the rat hippocampus as revealed by parvalbumin immunocytochemistry Anat Embryol 1991 184: 403–409 CAS Google Scholar
Pearce BD, Po CL, Pisell TL, Miller AH . Lymphocytic responses and the gradual hippocampal neuron loss following infection with lymphocytic choriomeningitis virus (LCMV) J Neuroimmunol 1999 101: 137–147 CASPubMed Google Scholar
de la Torre JC, Oldstone MBA . Anatomy of viral persistence: mechanisms of persistence and associated disease Adv Virus Res 1996 46: 311–343 CASPubMed Google Scholar
Stephenson J . Delay in treating schizophrenia may narrow therapeutic window of opportunity J Am Med Assoc 2000 283: 2091–2092 CAS Google Scholar
Todtenkopf MS, Benes FM . Distribution of glutamate decarboxylase65 immunoreactive puncta on pyramidal and nonpyramidal neurons in hippocampus of schizophrenic brain Synapse 1998 29: 323–332 CASPubMed Google Scholar