miRNAs and apoptosis: RNAs to die for (original) (raw)

• Alvarez-Garcia I, Miska EA . (2005). MicroRNA functions in animal development and human disease. Development 132: 4653–4662.
  Article CAS PubMed Google Scholar
• Ambros V . (2004). The functions of animal microRNAs. Nature 431: 350–355.
  Article CAS PubMed Google Scholar
• Bagga S, Bracht J, Hunter S, Massirer K, Holtz J, Eachus R et al. (2005). Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 122: 553–563.
  Article CAS PubMed Google Scholar
• Bartel DP . (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281–297.
  Article CAS PubMed Google Scholar
• Bernstein E, Caudy AA, Hammond SM, Hannon GJ . (2001). Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409: 363–366.
  Article CAS PubMed Google Scholar
• Bohnsack MT, Czaplinski K, Gorlich D . (2004). Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10: 185–191.
  Article CAS PubMed PubMed Central Google Scholar
• Bracken AP, Ciro M, Cocito A, Helin K . (2004). E2F target genes: unraveling the biology. Trends Biochem Sci 29: 409–417.
  Article CAS PubMed Google Scholar
• Brennecke J, Hipfner DR, Stark A, Russell RB, Cohen SM . (2003). Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113: 25–36.
  Article CAS PubMed Google Scholar
• Brennecke J, Stark A, Russell RB, Cohen SM . (2005). Principles of microRNA-target recognition. PLoS Biol 3: e85.
  Article CAS PubMed PubMed Central Google Scholar
• Brodsky MH, Weinert BT, Tsang G, Rong YS, McGinnis NM, Golic KG et al. (2004). Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage. Mol Cell Biol 24: 1219–1231.
  Article CAS PubMed PubMed Central Google Scholar
• Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E et al. (2002). Frequent deletions and down-regulation of microRNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99: 15524–15529.
  Article CAS PubMed PubMed Central Google Scholar
• Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S et al. (2004). Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 101: 2999–3004.
  Article CAS PubMed PubMed Central Google Scholar
• Chan JA, Krichevsky AM, Kosik KS . (2005). MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029–6033.
  Article CAS PubMed Google Scholar
• Chen P, Nordstrom W, Gish B, Abrams JM . (1996). Grim, a novel cell death gene in Drosophila. Genes Dev 10: 1773–1782.
  Article CAS PubMed Google Scholar
• Cheng AM, Byrom MW, Shelton J, Ford LP . (2005). Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 33: 1290–1297.
  Article CAS PubMed PubMed Central Google Scholar
• Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, Shimizu M et al. (2005). miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102: 13944–13949.
  Article CAS PubMed PubMed Central Google Scholar
• Cullen BR . (2004). Transcription and processing of human microRNA precursors. Mol Cell 16: 861–865.
  Article CAS PubMed Google Scholar
• Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ . (2004). Processing of primary microRNAs by the microprocessor complex. Nature 432: 231–235.
  Article CAS PubMed Google Scholar
• Doench JG, Petersen CP, Sharp PA . (2003). siRNAs can function as miRNAs. Genes Dev 17: 438–442.
  Article CAS PubMed PubMed Central Google Scholar
• Doench JG, Sharp PA . (2004). Specificity of microRNA target selection in translational repression. Genes Dev 18: 504–511.
  CAS PubMed PubMed Central Google Scholar
• Dyson N . (1998). The regulation of E2F by pRB-family proteins. Genes Dev 12: 2245–2262.
  Article CAS PubMed Google Scholar
• Edgar BA . (2006). From cell structure to transcription: Hippo forges a new path. Cell 124: 267–273.
  Article CAS PubMed Google Scholar
• Eis PS, Tam W, Sun L, Chadburn A, Li Z, Gomez MF et al. (2005). Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc Natl Acad Sci USA 102: 3627–3632.
  Article CAS PubMed PubMed Central Google Scholar
• Engles BM, Hutvagner G . (2006). Principles and effects of microRNA-mediated post-transcriptional gene regulation. Oncogene 25: 6163–6169.
  Article CAS Google Scholar
• Enright AJ, John B, Gaul U, Tuschl T, Sander C, Marks DS . (2003). MicroRNA targets in Drosophila. Genome Biol 5: R1.
  Article PubMed PubMed Central Google Scholar
• Esquela-Kerscher A, Slack FJ . (2006). Oncomirs – microRNAs with a role in cancer. Nat Rev Cancer 6: 259–269.
  CAS PubMed Google Scholar
• Evan G, Harrington E, Fanidi A, Land H, Amati B, Bennett M . (1994). Integrated control of cell proliferation and cell death by the c-myc oncogene. Philos Trans R Soc Lond B Biol Sci 345: 269–275.
  Article CAS PubMed Google Scholar
• Feng XH, Derynck R . (2005). Specificity and versatility in TGF-beta signaling through SMADS. Annu Rev Cell Dev Biol 21: 659–693.
  Article CAS PubMed Google Scholar
• Fernandez PC, Frank SR, Wang L, Schroeder M, Liu S, Greene J et al. (2003). Genomic targets of the human c-Myc protein. Genes Dev 17: 1115–1129.
  Article CAS PubMed PubMed Central Google Scholar
• Goyal L, McCall K, Agapite J, Hartwieg E, Steller H . (2000). Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function. EMBO J 19: 589–597.
  Article CAS PubMed PubMed Central Google Scholar
• Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N et al. (2004). The Microprocessor complex mediates the genesis of microRNAs. Nature 432: 235–240.
  Article CAS PubMed Google Scholar
• Grether ME, Abrams JM, Agapite J, White K, Steller H . (1995). The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev 9: 1694–1708.
  Article CAS PubMed Google Scholar
• Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I et al. (2001). Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. Elegans Dev Timing Cell 106: 23–34.
  Article CAS Google Scholar
• Gupta A, Gartner JJ, Sethupathy P, Hatzigeorgiou AG, Fraser NW . (2006). Anti-apoptotic function of a microRNA encoded by the HSV-1 latency-associated transcript. Nature 442: 82–86.
  Article CAS PubMed Google Scholar
• Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C et al. (2006). The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol 8: 27–36.
  Article CAS PubMed Google Scholar
• Hammond SM . (2006). MicroRNAs as oncogenes. Curr Opin Genet Dev 16: 4–9.
  Article CAS PubMed Google Scholar
• Han J, Lee Y, Yeom KH, Kim YK, Jin H, Kim VN . (2004). The Drosha-DGCR8 complex in primary microRNA processing. Genes Dev 18: 3016–3027.
  Article CAS PubMed PubMed Central Google Scholar
• Harbour JW, Dean DC . (2000). Rb function in cell-cycle regulation and apoptosis. Nat Cell Biol 2: E65–E67.
  Article CAS PubMed Google Scholar
• Hay BA . (2000). Understanding IAP function and regulation: a view from Drosophila. Cell Death Differ 7: 1045–1056.
  Article CAS PubMed Google Scholar
• He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S et al. (2005). A microRNA polycistron as a potential human oncogene. Nature 435: 828–833.
  Article CAS PubMed PubMed Central Google Scholar
• Hipfner DR, Weigmann K, Cohen SM . (2002). The bantam gene regulates Drosophila growth. Genetics 161: 1527–1537.
  CAS PubMed PubMed Central Google Scholar
• Holley CL, Olson MR, Colon-Ramos DA, Kornbluth S . (2002). Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition. Nat Cell Biol 4: 439–444.
  Article CAS PubMed PubMed Central Google Scholar
• Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD . (2001). A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293: 834–838.
  Article CAS PubMed Google Scholar
• Hutvagner G, Simard MJ, Mello CC, Zamore PD . (2004). Sequence-specific inhibition of small RNA function. PLoS Biol 2: E98.
  Article PubMed PubMed Central Google Scholar
• Hutvagner G, Zamore PD . (2002). A microRNA in a multiple-turnover RNAi enzyme complex. Science 297: 2056–2060.
  Article CAS PubMed Google Scholar
• Hwang HW, Mendell JT . (2006). MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 94: 776–780.
  Article CAS PubMed PubMed Central Google Scholar
• John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS . (2004). Human MicroRNA targets. PLoS Biol 2: e363.
  Article CAS PubMed PubMed Central Google Scholar
• Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A et al. (2005). RAS is regulated by the let-7 microRNA family. Cell 120: 635–647.
  Article CAS PubMed Google Scholar
• Justice RW, Zilian O, Woods DF, Noll M, Bryant PJ . (1995). The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. Genes Dev 9: 534–546.
  Article CAS PubMed Google Scholar
• Kent OA, Mendell JT . (2006). A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene 25: 6188–6196.
  Article CAS PubMed Google Scholar
• Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH . (2001). Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 15: 2654–2659.
  Article CAS PubMed PubMed Central Google Scholar
• Kim VN . (2005). Small RNAs: classification, biogenesis, and function. Mol Cells 19: 1–15.
  Article CAS PubMed Google Scholar
• Knight SW, Bass BL . (2001). A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans. Science 293: 2269–2271.
  Article CAS PubMed PubMed Central Google Scholar
• Kornbluth S, White K . (2005). Apoptosis in Drosophila: neither fish nor fowl (nor man, nor worm). J Cell Sci 118 (Part 9): 1779–1787.
  Article CAS PubMed Google Scholar
• Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T . (2001). Identification of novel genes coding for small expressed RNAs. Science 294: 853–858.
  Article CAS PubMed Google Scholar
• Lai EC . (2002). Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation. Nat Genet 30: 363–364.
  Article CAS PubMed Google Scholar
• Landthaler M, Yalcin A, Tuschl T . (2004). The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 14: 2162–2167.
  Article CAS PubMed Google Scholar
• Lau NC, Lim LP, Weinstein EG, Bartel DP . (2001). An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294: 858–862.
  Article CAS PubMed Google Scholar
• Leaman D, Chen PY, Fak J, Yalcin A, Pearce M, Unnerstall U et al. (2005). Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell 121: 1097–1108.
  Article CAS PubMed Google Scholar
• Lecellier CH, Dunoyer P, Arar K, Lehmann-Che J, Eyquem S, Himber C et al. (2005). A cellular microRNA mediates antiviral defense in human cells. Science 308: 557–560.
  Article CAS PubMed Google Scholar
• Lee RC, Ambros V . (2001). An extensive class of small RNAs in Caenorhabditis elegans. Science 294: 862–864.
  Article CAS PubMed Google Scholar
• Lee RC, Feinbaum RL, Ambros V . (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843–854.
  Article CAS PubMed Google Scholar
• Leone G, DeGregori J, Sears R, Jakoi L, Nevins JR . (1997). Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature 387: 422–426.
  Article CAS PubMed Google Scholar
• Lewis BP, Shih IH, Jones-Rhoades MW, Bartel DP, Burge CB . (2003). Prediction of mammalian microRNA targets. Cell 115: 787–798.
  Article CAS PubMed Google Scholar
• Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J et al. (2005). Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433: 769–773.
  Article CAS PubMed Google Scholar
• Lin YW, Sheu JC, Liu LY, Chen CH, Lee HS, Huang GT et al. (1999). Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: identification of three independent regions. Eur J Cancer 35: 1730–1734.
  Article CAS PubMed Google Scholar
• Lisi S, Mazzon I, White K . (2000). Diverse domains of THREAD/DIAP1 are required to inhibit apoptosis induced by REAPER and HID in Drosophila. Genetics 154: 669–678.
  CAS PubMed PubMed Central Google Scholar
• Llave C, Kasschau KD, Rector MA, Carrington JC . (2002). Endogenous and silencing-associated small RNAs in plants. Plant Cell 14: 1605–1619.
  Article CAS PubMed PubMed Central Google Scholar
• Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D et al. (2005). MicroRNA expression profiles classify human cancers. Nature 435: 834–838.
  Article CAS PubMed Google Scholar
• Lund E, Guttinger S, Calado A, Dahlberg JE, Kutay U . (2004). Nuclear export of microRNA precursors. Science 303: 95–98.
  Article CAS PubMed Google Scholar
• Martinez J, Patkaniowska A, Urlaub H, Luhrmann R, Tuschl T . (2002). Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110: 563–574.
  Article CAS PubMed Google Scholar
• Matsumura I, Tanaka H, Kanakura Y . (2003). E2F1 and c-Myc in cell growth and death. Cell Cycle 2: 333–338.
  Article CAS PubMed Google Scholar
• Meister G, Landthaler M, Dorsett Y, Tuschl T . (2004). Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA 10: 544–550.
  Article CAS PubMed PubMed Central Google Scholar
• Mendell JT . (2005). MicroRNAs: critical regulators of development, cellular physiology and malignancy. Cell Cycle 4: 1179–1184.
  Article CAS PubMed Google Scholar
• Metzler M, Wilda M, Busch K, Viehmann S, Borkhardt A . (2004). High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer 39: 167–169.
  Article CAS PubMed Google Scholar
• Michael MZ, SM OC, van Holst Pellekaan NG, Young GP, James RJ . (2003). Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 1: 882–891.
  CAS PubMed Google Scholar
• Nairz K, Rottig C, Rintelen F, Zdobnov E, Moser M, Hafen E . (2006). Overgrowth caused by misexpression of a microRNA with dispensable wild-type function. Dev Biol 291: 314–324.
  Article CAS PubMed Google Scholar
• Neufeld TP, de la Cruz AF, Johnston LA, Edgar BA . (1998). Coordination of growth and cell division in the Drosophila wing. Cell 93: 1183–1193.
  Article CAS PubMed Google Scholar
• Nordstrom W, Chen P, Steller H, Abrams JM . (1996). Activation of the reaper gene during ectopic cell killing in Drosophila. Dev Biol 180: 213–226.
  Article CAS PubMed Google Scholar
• O’Donnell KA, Wentzel EA, Zeller KI, Dang CV, Mendell JT . (2005). c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435: 839–843.
  Article CAS PubMed Google Scholar
• Ota A, Tagawa H, Karnan S, Tsuzuki S, Karpas A, Kira S et al. (2004). Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res 64: 3087–3095.
  Article CAS PubMed Google Scholar
• Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B et al. (2000). Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature 408: 86–89.
  Article CAS PubMed Google Scholar
• Pelengaris S, Khan M, Evan GI . (2002). Suppression of Myc-induced apoptosis in beta cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell 109: 321–334.
  Article CAS PubMed Google Scholar
• Perng GC, Jones C, Ciacci-Zanella J, Stone M, Henderson G, Yukht A et al. (2000). Virus-induced neuronal apoptosis blocked by the herpes simplex virus latency-associated transcript. Science 287: 1500–1503.
  Article CAS PubMed Google Scholar
• Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE et al. (2000). The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 403: 901–906.
  Article CAS PubMed Google Scholar
• Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP . (2002). MicroRNAs in plants. Genes Dev 16: 1616–1626.
  Article CAS PubMed PubMed Central Google Scholar
• Rodriguez A, Griffiths-Jones S, Ashurst JL, Bradley A . (2004). Identification of mammalian microRNA host genes and transcription units. Genome Res 14: 1902–1910.
  Article CAS PubMed PubMed Central Google Scholar
• Rorth P . (1996). A modular misexpression screen in Drosophila detecting tissue-specific phenotypes. Proc Natl Acad Sci USA 93: 12418–12422.
  Article CAS PubMed PubMed Central Google Scholar
• Salvesen GS, Abrams JM . (2004). Caspase activation – stepping on the gas or releasing the brakes? Lessons from humans and flies. Oncogene 23: 2774–2784.
  Article CAS PubMed Google Scholar
• Schuster N, Krieglstein K . (2002). Mechanisms of TGF-beta-mediated apoptosis. Cell Tissue Res 307: 1–14.
  Article CAS PubMed Google Scholar
• Schutz S, Sarnow P . (2006). Interaction of viruses with the mammalian RNA interference pathway. Virology 344: 151–157.
  Article CAS PubMed Google Scholar
• Slack FJ, Weidhaas JB . (2006). MicroRNAs as a potential magic bullet in cancer. Future Oncol 2: 73–82.
  Article CAS PubMed Google Scholar
• Stark A, Brennecke J, Russell RB, Cohen SM . (2003). Identification of Drosophila MicroRNA targets. PLoS Biol 1: E60.
  Article PubMed PubMed Central Google Scholar
• Sullivan CS, Ganem D . (2005). MicroRNAs and viral infection. Mol Cell 20: 3–7.
  Article CAS PubMed Google Scholar
• Teleman AA, Chen YW, Cohen SM . (2005). Drosophila melted modulates FOXO and TOR activity. Dev Cell 9: 271–281.
  Article CAS PubMed Google Scholar
• Teleman AA, Maitra S, Cohen SM . (2006). Drosophila lacking microRNA miR-278 are defective in energy homeostasis. Genes Dev 20: 417–422.
  Article CAS PubMed PubMed Central Google Scholar
• Tittel JN, Steller H . (2000). A comparison of programmed cell death between species. Genome Biol 1: REVIEWS0003.
  Article CAS PubMed PubMed Central Google Scholar
• Trimarchi JM, Lees JA . (2002). Sibling rivalry in the E2F family. Nat Rev Mol Cell Biol 3: 11–20.
  Article CAS PubMed Google Scholar
• Valencia-Sanchez MA, Liu J, Hannon GJ, Parker R . (2006). Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev 20: 515–524.
  Article CAS PubMed Google Scholar
• White K, Grether ME, Abrams JM, Young L, Farrell K, Steller H . (1994). Genetic control of programmed cell death in Drosophila. Science 264: 677–683.
  Article CAS PubMed Google Scholar
• Wightman B, Ha I, Ruvkun G . (1993). Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75: 855–862.
  Article CAS PubMed Google Scholar
• Wolff T, Ready DF . (1993). Pattern formation in the Drosphila retina. In: Bate M, Martinez Arias A (eds). The Development of Drosophila Melanogaster. Cold Spring Harbor Laboratory: Plainview, NY, pp 1277–1325.
  Google Scholar
• Xu P, Vernooy SY, Guo M, Hay BA . (2003). The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. Curr Biol 13: 790–795.
  Article CAS PubMed Google Scholar
• Yi R, Qin Y, Macara IG, Cullen BR . (2003). Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 17: 3011–3016.
  Article CAS PubMed PubMed Central Google Scholar
• Yoo SJ, Huh JR, Muro I, Yu H, Wang L, Wang SL et al. (2002). Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms. Nat Cell Biol 4: 416–424.
  Article CAS PubMed Google Scholar
• Zeng Y . (2006). Principles of micro-RNA production and maturation. Oncogene 25: 6156–6162.
• Zeng Y, Wagner EJ, Cullen BR . (2002). Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol Cell 9: 1327–1333.
  Article CAS PubMed Google Scholar
• Zeng Y, Yi R, Cullen BR . (2003). MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci USA 100: 9779–9784.
  Article CAS PubMed PubMed Central Google Scholar