Somatic mutations of the mitochondrial genome in human colorectal tumours (original) (raw)

References

  1. Warburg, O. On the origin of cancer cells. Science 123, 309–314 (1956).
    Article CAS Google Scholar
  2. Kroemer, G., Zamzami, N. & Susin, S.A. Mitochondrial control of apoptosis. Immunol. Today 18, 45–51 (1997).
    Article Google Scholar
  3. Korsmeyer, S.J., Yin, X.M., Oltvai, Z.N., Veis-Novack, D.J. & Linette, G.P. Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family. Biochim. Biophys. Acta 1271, 63–66 (1995).
    Article Google Scholar
  4. Rudin, C.M. & Thompson, C.B. Apoptosis and disease: regulation and clinical relevance of programmed cell death. Annu. Rev. Med. 48, 267–281 (1997).
    Article CAS Google Scholar
  5. Wang, H.G. & Reed, J.C. Mechanisms of Bcl-2 protein function. Histol. Histopathol. 13, 521– 530 (1998).
    CAS PubMed Google Scholar
  6. Cavalli, L.R. & Liang, B.C. Mutagenesis, tumorigenicity, and apoptosis: are the mitochondria involved? Mutat. Res. 398, 19–26 (1998).
    Article CAS Google Scholar
  7. Chen, L.B. Mitochondrial membrane potential in living cells. Annu. Rev. Cell Biol. 4, 155–181 (1988).
    Article CAS Google Scholar
  8. Augenlicht, L.H. & Heerdt, B.G. Modulation of gene expression as a biomarker in colon. J. Cell. Biochem. Suppl. 16G, 151–157 (1992).
    Article CAS Google Scholar
  9. Lightowlers, R.N., Chinnery, P.F., Turnbull, D.M. & Howell, N. Mammalian mitochondrial genetics: heredity, heteroplasmy and disease. Trends Genet. 13, 450–455 (1997).
    Article CAS Google Scholar
  10. Beal, M. Mitochondria, free radicals, and neurodegeneration. Curr. Opin. Neurobiol. 6, 661–666 (1996).
    Article CAS Google Scholar
  11. Li, Y., Zhou, H., Stansbury, K. & Trush, M. Role of reactive oxygen species in multistage carcinogenesis. in Oxygen radicals and the disease process (eds Thomas, C. & Kalyanaraman, B.) 237–277 (Harwood Academic Publishers, Amsterdam, The Netherlands, 1997).
    Google Scholar
  12. Croteau, D.L. & Bohr, V.A. Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J. Biol. Chem. 272, 25409–25412 (1997).
    Article CAS Google Scholar
  13. Parfait, B., Rustin, P., Munnich, A. & Rotig, A. Co-amplification of nuclear pseudogenes and assessment of heteroplasmy of mitochondrial DNA mutations. Biochem. Biophys. Res. Commun. 247, 57–59 (1998).
    Article CAS Google Scholar
  14. Beckman, K.B. & Ames, B.N. Oxidative decay of DNA. J. Biol. Chem. 272, 19633–19636 (1997).
    Article CAS Google Scholar
  15. Cadet, J., Berger, M., Douki, T. & Ravanat, J.L. Oxidative damage to DNA: formation, measurement, and biological significance. Rev. Physiol. Biochem. Pharmacol. 131, 1– 87 (1997).
    CAS PubMed Google Scholar
  16. Wallace, D.C., Brown, M.D., Melov, S., Graham, B. & Lott, M. Mitochondrial biology, degenerative diseases and aging. Biofactors 7, 187–190 (1998).
    Article CAS Google Scholar
  17. Shay, J. & Ishii, S. Unexpected nonrandom mitochondrial DNA segregation in human cell hybrids. Anticancer Res. 10, 279–284 (1990).
    CAS PubMed Google Scholar
  18. Lengauer, C., Kinzler, K.W. & Vogelstein, B. Genetic instability in colorectal cancers. Nature 386, 623–627 (1997).
    Article CAS Google Scholar
  19. Khrapko, K. et al. Mitochondrial mutational spectra in human cells and tissues. Proc. Natl Acad. Sci. USA 94, 13798– 13803 (1997).
    Article CAS Google Scholar
  20. Beckman, K. & Ames, B. Detection and quantification of oxidative adducts of mitochondrial DNA. Methods Enzymol. 264, 442–453 (1996).
    Article CAS Google Scholar
  21. Welter, C., Kovacs, G., Seitz, G. & Blin, N. Alteration of mitochondrial DNA in human oncocytomas. Genes Chromosomes Cancer 1, 79–82 (1989).
    Article CAS Google Scholar
  22. Yamamoto, H. et al. Significant existence of deleted mitochondrial DNA in cirrhotic liver surrounding hepatic tumor. Biochem. Biophys. Res. Commun. 182, 913–920 (1992).
    Article CAS Google Scholar
  23. Burgart, L.J., Zheng, J., Shu, Q., Strickler, J.G. & Shibata, D. Somatic mitochondrial mutation in gastric cancer. Am. J. Pathol. 147, 1105–1111 (1995).
    CAS PubMed PubMed Central Google Scholar
  24. Tallini, G., Ladanyi, M., Rosai, J. & Jhanwar, S. Analysis of nuclear and mitochondrial DNA alterations in thyroid and renal oncocytic tumour. Cytogenet. Cell. Genet. 66, 253–259 (1994).
    Article CAS Google Scholar
  25. Heerdt, B.G., Chen, J., Stewart, L.R. & Augenlicht, L.H. Polymorphisms, but lack of mutations or instability, in the promotor region of the mitochondrial genome in human colonic tumors. Cancer Res. 54, 3912–3915 (1994).
    CAS PubMed Google Scholar
  26. Wallace, D.C. Mitochondrial DNA sequence variation in human evolution and disease. Proc. Natl Acad. Sci. USA 91, 8739– 8746 (1994).
    Article CAS Google Scholar
  27. Attardi, G., Yoneda, M. & Chomyn, A. Complementation and segregation behavior of disease-causing mitochondrial DNA mutations in cellular model systems. Biochim. Biophys. Acta 1271, 241–248 (1995).
    Article Google Scholar
  28. Chee, M. et al. Accessing genetic information with high-density DNA arrays. Science 274, 610–614 (1996).
    Article CAS Google Scholar
  29. Parsons, R. et al. Microsatellite instability and mutations of the transforming growth factor b type II receptor gene in colorectal cancer. Cancer Res. 55, 5548–5550 (1995).
    CAS Google Scholar
  30. Jen, J. et al. Allelic loss of chromosome 18q and prognosis in colorectal cancer. N. Engl. J. Med. 331, 213– 221 (1994).
    Article CAS Google Scholar
  31. Armour, J.A., Neumann, R., Gobert, S. & Jeffreys, A.J. Isolation of human simple repeat loci by hybridization selection. Hum. Mol. Genet. 3, 599–665 (1994).
    Article CAS Google Scholar
  32. Hofhaus, G. & Attardi, G. Efficient selection and characterization of mutants of a human cell line which are defective in mitochondrial DNA-encoded subunits of respiratory NADH dehydrogenase. Mol. Cell. Biol. 15, 964–974 (1995).
    Article CAS Google Scholar

Download references