Reversible disruption of pericentric heterochromatin and centromere function by inhibiting deacetylases (original) (raw)
Lamond, A. I. & Earnshaw, W. C. Structure and function in the nucleus. Science280, 547– 553 (1998). ArticleCAS Google Scholar
Cockell, M. & Gasser, S. M. Nuclear compartments and gene regulation. Curr. Opin. Genet. Dev.9, 199 –205 (1999). ArticleCAS Google Scholar
Dobie, K. W., Hari, K. L., Maggert, K. A. & Karpen, G. H. Centromere proteins and chromosome inheritance: a complex affair. Curr. Opin. Genet. Dev.9, 206–217 (1999). ArticleCAS Google Scholar
Craig, J. M., Earnshaw, W. C. & Vagnarelli, P. Mammalian centromeres: DNA sequence, protein composition, and role in cell cycle progression. Exp. Cell Res.246, 249–262 (1999). ArticleCAS Google Scholar
Eissenberg, J. C. & Elgin, S. C. The HP1 protein family: getting a grip on chromatin. Curr. Opin. Genet. Dev.10, 204–210 (2000). ArticleCAS Google Scholar
Jones, D. O., Cowel, I. G. & Singh, P. B. Mammalian chromodomain proteins: their role in genome organisation and expression. Bioessays22, 124–137 (2000). ArticleCAS Google Scholar
Wakimoto, B. T. Beyond the nucleosome: epigenetic aspects of position–effect variegation in Drosophila. Cell93, 321– 324 (1998). ArticleCAS Google Scholar
Festenstein, R. et al. Heterochromatin protein 1 modifies mammalian PEV in a dose- and chromosomal-context-dependent manner. Nature Genet.23, 457–461 (1999). ArticleCAS Google Scholar
Ekwall, K. et al. The chromodomain protein Swi6: a key component at fission yeast centromeres. Science269, 1429– 1431 (1995). ArticleCAS Google Scholar
Kellum, R. & Alberts, B. M. Heterochromatin protein 1 is required for correct chromosome segregation in Drosophila embryos. J. Cell Sci.108, 1419–1431 (1995). CASPubMed Google Scholar
Turner, B. M. Histone acetylation as an epigenetic determinant of long-term transcriptional competence. Cell. Mol. Life Sci.54, 21– 31 (1998). ArticleCAS Google Scholar
Strahl, B. D. & Allis, C. D. The language of covalent histone modifications. Nature403, 41– 45 (2000). ArticleCAS Google Scholar
Grunstein, M. Yeast heterochromatin: regulation of its assembly and inheritance by histones . Cell93, 325–328 (1998). ArticleCAS Google Scholar
Ekwall, K., Olsson, T., Turner, B. M., Cranston, G. & Allshire, R. C. Transient inhibition of histone deacetylation alters the structural and functional imprint at fission yeast centromeres. Cell91, 1021– 1032 (1997). ArticleCAS Google Scholar
Grewal, S. I., Bonaduce, M. J. & Klar, A. J. Histone deacetylase homologs regulate epigenetic inheritance of transcriptional silencing and chromosome segregation in fission yeast. Genetics150, 563– 576 (1998). CASPubMedPubMed Central Google Scholar
Taddei, A., Roche, D., Sibarita, J.B., Turner, B. M. & Almouzni, G. Duplication and maintenance of heterochromatin domains. J. Cell Biol.147, 1153–1166 (1999). ArticleCAS Google Scholar
Rea, S. et al. Regulation of chromatin structure by site-specific histone H3 methyltransferases . Nature406, 593–599 (2000). ArticleCAS Google Scholar
Paro, R. Chromatin regulation. Formatting genetic text. Nature406, 579–580 (2000). ArticleCAS Google Scholar
Yoshida, M., Horinouchi, S. & Beppu, T. Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and function. Bioessays17, 423–430 ( 1995). ArticleCAS Google Scholar
Cerda, M. C., Berrios, S., Fernandez-Donoso, R., Garagna, S. & Redi, C. Organisation of complex nuclear domains in somatic mouse cells. Biol. Cell91, 55 –65 (1999). ArticleCAS Google Scholar
Habib, M. et al. DNA global hypomethylation in EBV-transformed interphase nuclei . Exp. Cell Res.249, 46– 53 (1999). ArticleCAS Google Scholar
Earnshaw, W. C. & Rothfield, N. Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma. Chromosoma91, 313– 321 (1985). ArticleCAS Google Scholar
Belyaev, N. D., Keohane, A. M. & Turner, B. M. Histone H4 acetylation and replication timing in Chinese hamster chromosomes. Exp. Cell Res.225, 277–285 (1996). ArticleCAS Google Scholar
Misteli, T. & Spector, D. L. The cellular organization of gene expression. Curr. Opin. Cell Biol.10, 323–331 (1998). ArticleCAS Google Scholar
Puvion-Dutilleul, F. et al. Alterations of nucleolar ultrastructure and ribosome biogenesis by actinomycin D. Implications for U3 snRNP function. Eur. J. Cell Biol.58, 149–162 ( 1992). CASPubMed Google Scholar
Marheineke, K. & Krude, T. Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle. J. Biol. Chem.273, 15279–15286 (1998). ArticleCAS Google Scholar
Martini, E, Roche, D. M., Marheineke, K., Verreault, A. & Almouzni, G. Recruitment of phosphorylated chromatin assembly factor 1 to chromatin after UV irradiation of human cells. J. Cell Biol.143, 563–575 (1998). ArticleCAS Google Scholar
Remboutsika, E. et al. The putative nuclear receptor mediator TIF1α is tightly associated with euchromatin. J. Cell Sci.112, 1671–1683 (1999). CAS Google Scholar
Nielsen, A. L. et al. Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. EMBO J.18 , 6385–6395 (1999). ArticleCAS Google Scholar
Dini, L., Coppola, S., Ruzittu, M. T. & Ghibelli, L. Multiple pathways for apoptotic nuclear fragmentation. Exp. Cell Res.223, 340–347 ( 1996). ArticleCAS Google Scholar
Marrazzini, A., Betti, C., Bernacchi, F., Barrai, I. & Barale, R. Micronucleus test and metaphase analyses in mice exposed to known and suspected spindle poisons. Mutagenesis9, 505–515 (1994). ArticleCAS Google Scholar
Shimizu, N., Itoh, N., Utiyama, H. & Wahl, G. M. Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase. J. Cell Biol.140, 1307– 1320 (1998). ArticleCAS Google Scholar
Sogo, J. M. & Laskey, R. A. in Chromatin Structure and Gene Expression (ed. Elgin, S. C. R.) 49–71 (Oxford Univ. Press, New York, 1995). Google Scholar
Zhao, T., Heyduk, T., Allis, C. D. & Eissenberg, J. C. Heterochromatin protein 1 binds to nucleosomes and DNA in vitro. J. Biol. Chem.275, 28332–28338 ( 2000). CASPubMed Google Scholar
Knoepfler, P. S. & Eisenman, R. N. Sin meets NuRD and other tails of repression. Cell99, 447–450 (1999). ArticleCAS Google Scholar
Robertson, K. D. et al. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nature Genet.25, 338–342 (2000). ArticleCAS Google Scholar
Rountree, M. R., Bachman, K. E. & Baylin, S. B. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nature Genet.25, 269–277 (2000). ArticleCAS Google Scholar
Xu, G. L. et al. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature402 , 187–191 (1999). ArticleCAS Google Scholar
Turner, B. M. & Fellows, G. Specific antibodies reveal ordered and cell-cycle-related use of histone-H4 acetylation sites in mammalian cells . Eur. J. Biochem.179, 131– 139 (1989). ArticleCAS Google Scholar
Maison, C., Pyrpasopoulou, A. & Georgatos, S. D. Vimentin-associated mitotic vesicles interact with chromosomes in a lamin B- and phosphorylation-dependent manner. EMBO J.14, 3311–3324 ( 1995). ArticleCAS Google Scholar