Identification of XAF1 as an antagonist of XIAP anti-Caspase activity (original) (raw)

References

Roy, N. et al. The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy. Cell 80, 167–178 (1995).
Article CAS Google Scholar
Rothe, M., Pan, M., Henzel, W. L. ., Ayres, T. M. & Goeddel, D. V. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins. Cell 83, 1243–1252 (1995).
Article CAS Google Scholar
Liston, P. et al. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature 379, 349–353 (1996).
Article CAS Google Scholar
Duckett, C. S. et al. A conserved family of cellular genes related to the baculovirus iap gene and encoding apoptosis inhibitors. EMBO J. 15, 2685–2694 (1996).
Article CAS Google Scholar
Uren, A. G., Pakusch, M., Hawkins, C. J., Puls, K. L. & Vaux, D. L. Cloning and expression of apoptosis inhibitory protein homologues that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc. Natl Acad. Sci. USA 93, 4974–4978 (1996).
Article CAS Google Scholar
Ambrosini, G., Adida, C. & Altieri, D.C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nature Med. 3, 917–921 (1997).
Article CAS Google Scholar
Deveraux, Q. L., Takahashi, R., Salvesen, G. S. & Reed, J. C. X-linked IAP is a direct inhibitor of cell death proteases. Nature 388, 300–304 (1997).
Article CAS Google Scholar
Roy, N., Deveraux, Q. L., Takahashi, R., Salvesen, G. S. & Reed, J. C. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16, 6914–6925 (1997).
Article CAS Google Scholar
Deveraux, Q. L. et al. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 17, 2215–2223 (1998).
Article CAS Google Scholar
Takahashi, R. et al. A single BIR domain of XIAP sufficient for inhibiting caspases. J. Biol. Chem. 273, 7787–7790 (1998).
Article CAS Google Scholar
Kobayashi, K., Hatano, M., Otaki, M., Ogasawara, T. & Tokuhisa, T. Expression of a murine homologue of the inhibitor of apoptosis protein is related to cell proliferation. Proc. Natl Acad. Sci. USA 96, 1457–1462 (1999).
Article CAS Google Scholar
Tamm, I. et al. IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 58, 5315–5320 (1998).
CAS PubMed Google Scholar
Deveraux, Q. L. et al. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases. EMBO J. 18, 5242–5251 (1999).
Article CAS Google Scholar
Yang, Y., Fang, S., Jensen, J.P., Weissman, A. M. & Ashwell, J. D. Ubiquitin protein ligase activity of IAPs and their degradation in proteosomes in response to apoptotic stimuli. Science 288, 874–877 (2000).
Article CAS Google Scholar
Huang, H.-K. et al. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. J. Biol. Sci. 275, 26661–26664 (2000).
CAS Google Scholar
Yamaguchi, K. et al. XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J. 18,179–187.
Hofer-Warbinek, R. et al. Activation of NF-Kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1. J. Biol. Sci. 275, 22064–22068 (2000).
CAS Google Scholar
Fong, W. G. et al. Expression and genetic analysis of XIAP associated factor 1 (XAF1) in cancer cell lines. Genomics 70, 113–122 (2000).
Article CAS Google Scholar
Alam, A., Cohen, L. Y., Aouad, S. & Sekaly, R. P. Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells. J. Exp. Med. 190, 1879–1890 (1999).
Article CAS Google Scholar
Kennedy, N. J., Kataoka, T., Tschopp, J. & Budd, R. C. caspase activation is required for T cell proliferation. J. Exp. Med. 190, 1891–1896 (1999).
Article CAS Google Scholar
Shu, H.-B., Takeuchi, M. & Goeddel, D. V. The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. Proc. Natl Acad. Sci. USA 93, 13973–13978 (1996).
Article CAS Google Scholar
Vucic, D., Kaiser, W. J. & Miller, L. K. Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM. Mol. Cell Biol. 18, 3300–3309 (1998).
Article CAS Google Scholar
Goyal, L., McCall, K., Apapite, J., Hartwieg, E. & Steller, H. Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function. EMBO J. 19, 589–597 (2000).
Article CAS Google Scholar
Wang, S. L., Hawkins, C. J., Yoo, S. J., Muller, H. A. J. & Hay, B. A. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell 98, 453–463 (1999).
Article CAS Google Scholar
Du, C., Fang, M., Li, Y., Li, L. & Wang, X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102, 33–42 (2000).
Article CAS Google Scholar
Verhagen, A. M. et al. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102, 43–53 (2000).
Article CAS Google Scholar
Miyake, S. et al. Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl Acad. Sci. USA 93, 1320–1324 (1996).
Article CAS Google Scholar
Li, J. et al. Expression of inhibitor of apoptosis proteins (IAPs) in rat granulosa cells during ovarian follicular development and atresia. Endocrinology 139, 1321–1328 (1998).
Article CAS Google Scholar
Xu, D. G. et al. Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus. Nature Med. 3, 997–1004 (1997).
Article CAS Google Scholar

Download references