Shikama, N., Lyon, J. & La Thangue, N. B. The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol.7, 230–236 (1997). ArticleCAS Google Scholar
Goodman, R. H. & Smolik, S. CBP/p300 in cell growth, transformation, and development. Genes Dev.14, 1553–1577 (2000). CASPubMed Google Scholar
Hassig, C. A. & Schrieber, S. L. Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs. Curr. Opin.1, 300–308 (1997). ArticleCAS Google Scholar
Brown, C. E., Lechner, T., Howe, L. & Workman, J. L. The many HATs of transcription co-activators. Trends Biol. Sci.25, 15–18 (2000). ArticleCAS Google Scholar
Gu, W. & Roeder, R. G. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell90, 595–606 (1997). ArticleCAS Google Scholar
Sakaguchi, K. et al. DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev.12, 2831–2841 (1998). ArticleCAS Google Scholar
Martinez-Balbás, M. A., Bauer, U.-M., Nielsen, S. J., Brehm, A. & Kouzarides, T. Regulation of E2F-1 activity by acetylation. EMBO J.19, 662–271 (2000). Article Google Scholar
Muraoka, M. et al. p300 gene alterations in colorectal and gastric carcinomas. Oncogene12, 1565–1569 (1996). CASPubMed Google Scholar
Gayther, S. A. et al. Mutations truncating the EP300 acetylase in human cancers. Nature Genet.24, 300–303 (2000). ArticleCAS Google Scholar
Giles, R. H., Peters, D. J. & Bruening, M. H. Conjunction dysfunction: CBP/p300 in human disease. Trends Genet.14, 178–183 (1998). ArticleCAS Google Scholar
Kung, A. L. et al. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev.14, 272–277 (2000). CASPubMedPubMed Central Google Scholar
Dyson, N. & Harlow, E. Adenovirus E1A targets key regulators of cell proliferation. Cancer Surv.12, 161–195 (1992). CASPubMed Google Scholar
Stein, R. W., Corrigan, M., Yaciul, P., Whelan, J. & Moran, E. Analysis of E1A-mediated growth regulation functions: binding of the p300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity. J. Virol.64, 4421–4427 (1990). CASPubMedPubMed Central Google Scholar
Wang, H.-G. H., Moran, E. & Yacuik, P. E1A promotes association between p300 and pRB in multimeric complexes required for normal biological activity. J. Virol.69, 7917–7924 (1995). CASPubMedPubMed Central Google Scholar
Yao, T.-P. et al. Gene dosage-dependent embryonic development and proliferation defects in micelacking the transcriptional integrator p300. Cell93, 361–372 (1998). ArticleCAS Google Scholar
Ait-Si-Ali, S. et al. CBP/p300 histone acetyltransferase activity is important for the G1/S transition. Oncogene19, 2430–2437 (2000). ArticleCAS Google Scholar
Ait-Si-Ali, S. et al. Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A. Nature396, 184–186 (1998). ArticleCAS Google Scholar
Bandara, L. R., Adamczewski, J. P., Hunt, T. & La Thangue, N. B. Cyclin A and the retinoblastoma gene product complex with a common transcription factor. Nature352, 249–251 (1991). ArticleCAS Google Scholar
Yang, X.-J., Ogryzko, V. V., Nishikawa, J.-I., Howard, B. H. & Nakatani, Y. A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature382, 319–324 (1996). ArticleCAS Google Scholar
Arany, Z., Newsome, D., Oldread, E., Livingston, D. M. & Eckner, R. A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature374, 81–84 (1995). ArticleCAS Google Scholar
Kraus, V. B., Moran, E. & Nevins, J. R. Promoter-specific _trans_-activation by the adenovirus E1A12S product involves separate E1A domains. Mol. Cell. Biol.12, 4391–4399 (1992). ArticleCAS Google Scholar
Lassam, N. J., Bayley, S. T. & Graham, F. L. Tumor antigens of human Ad5 in transformed cells and in cells infected with transformation-defective host-range mutants. Cell18, 781–791 (1979). ArticleCAS Google Scholar
Xiao, Z.-X. et al. Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature375,964–698 (1995). Article Google Scholar
Adams, P. D. et al. Identification of a cyclin-Cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol. Cell. Biol.16, 6623–6633 (1996). ArticleCAS Google Scholar
Zhang, W., Bone, J. R., Edmondson, D. G., Turner, B. M. & Roth, S. Y. Essential and redundant functions of histone acetylation revealed by mutation of target lysines and loss of the Gcn5p acetyltransferase. EMBO J.17, 3155–3167 (1998). ArticleCAS Google Scholar
Zhang, Q., Yao, H., Vo, N. & Goodman, R. H. Acetylation of adenovirus E1A regulates binding of the transcriptional co-repressor CtBP. Proc. Natl Acad. Sci. USA97, 14323–14328 (2000). ArticleCAS Google Scholar
Zhang, W. & Bieker, J. J. Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases. Proc. Natl Acad. Sci. USA95, 9855–9860 (1998). ArticleCAS Google Scholar
Boyes, J., Byfield, P., Nakatani, Y. & Ogryzko, V. Regulation of activity of the transcription factor GATA-1 by acetylation. Nature396, 594–598 (1998). ArticleCAS Google Scholar
Sartorelli, V. et al. Acetylation of MyoD directed by pCAF is necessary for the execution of the muscle program. Mol Cell.4, 725–734 (1999). ArticleCAS Google Scholar
Keirnan, R. et al. HIV-1 Tat transcriptional activity is regulated by acetylation. EMBO J.18, 6106–6118 (1999). Article Google Scholar
Hseih, J. K. et al. RB regulates the stability and the apoptotic function of p53 via MDM2. Mol. Cell3, 181–193 (1999). Article Google Scholar
Lee, C.-W., Sørensen, T. S., Shikama, N. & La Thangue, N. B. Functional interplay between p53 and E2F through co-activator p300. Oncogene16, 2695–2610 (1998). ArticleCAS Google Scholar
Shikama, N. et al. A novel co-factor for p300 that regulates the p53 response. Mol. Cell4, 365–376 (1999). ArticleCAS Google Scholar
Ogryzko, V., Schiltz, R. L., Russanova, V., Howard, B. H. & Nakatani, Y. The transcriptional co-activators p300 and CBP are histone acetyltransferases. Cell87, 953–959 (1996). ArticleCAS Google Scholar
Morris, L., Allen, K. E. & La Thangue, N. B. Regulation of E2F transcription by cyclinE/Cdk2 kinase mediated through p300/CBP co-activators. Nature Cell Biol.12, 232–239 (2000). Article Google Scholar
Loughran, Ö. & La Thangue, N. B. Apoptotic and growth-promoting activity of E2F modulated by MDM2. Mol. Cell Biol.20, 2186–2197 (2000). ArticleCAS Google Scholar
Shikama, N. et al. Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family co-activators. Mol. Cell Biol.20, 8933–8943 (2000). ArticleCAS Google Scholar
de la Luna, S., Allen, K. E., Mason, S. L. & La Thangue, N. B. Integration of a growth suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor. EMBO J.18, 212–228 (1999). ArticleCAS Google Scholar