Cell fusion causes confusion (original) (raw)

Stem cells

Nature volume 416, pages 485–487 (2002)Cite this article

'Transdifferentiation' is a poorly understood process invoked to explain how tissue-specific adult stem cells can generate cells of other tissues. New results challenge its existence.

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Figure 1: Can adult stem cells transdifferentiate into other cell types?

References

  1. Gardner, R. L. & Beddington, R. S. J. Cell Sci. 10 (suppl.), 11–27 (1988).
    Article CAS Google Scholar
  2. Ying, Q.-L, Nichols, J., Evans, E. P. & Smith, A. G. Nature 416, 545–548 (2002); online 13 March 2002 (DOI 10.1038/nature729).
    Article ADS CAS Google Scholar
  3. Terada, N. et al. Nature 416, 542–545 (2002); online 13 March 2002 (DOI 10.1038/nature730).
    Article ADS CAS Google Scholar
  4. Clarke, D. L. et al. Science 288, 1660–1663 (2000).
    Article ADS CAS Google Scholar
  5. Galli, R. et al. Nature Neurosci. 3, 986–991 (2000).
    Article CAS Google Scholar
  6. Rietze, R. L. et al. Nature 412, 736–739 (2001).
    Article ADS CAS Google Scholar
  7. Condorelli, G. et al. Proc. Natl Acad. Sci. USA 98, 10733–10738 (2001).
    Article ADS CAS Google Scholar
  8. Yeom, Y. I. et al. Development 122, 881–894 (1996).
    CAS Google Scholar
  9. Priller, J. et al. J. Cell Biol. 155, 733–738 (2001).
    Article CAS Google Scholar
  10. Clague, M. J. Curr. Biol. 9, R258–R260 (1999).
    Article CAS Google Scholar

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Authors and Affiliations

  1. Laboratory of Genetics, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, 92037, California, USA
    Andrew E. Wurmser & Fred H. Gage

Authors

  1. Andrew E. Wurmser
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  2. Fred H. Gage
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Correspondence toFred H. Gage.

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Wurmser, A., Gage, F. Cell fusion causes confusion.Nature 416, 485–487 (2002). https://doi.org/10.1038/416485a

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