Crime and punishment (original) (raw)

Cancer

Nature volume 436, pages 636–637 (2005)Cite this article

Cellular senescence stops the growth of cells. This process, first glimpsed in cell culture, is now confirmed by in vivo evidence as a vital mechanism that constrains the malignant progression of many tumours.

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Figure 1: A senescence wiring diagram.

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Authors and Affiliations

  1. Departments of Medicine and Genetics, The Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, 27599-7295, North Carolina, USA
    Norman E. Sharpless
  2. Department of Medical Oncology, and the Departments of Medicine and Genetics, Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street (M413), Boston, 02115, Massachusetts, USA
    Ronald A. DePinho

Authors

  1. Norman E. Sharpless
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  2. Ronald A. DePinho
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Sharpless, N., DePinho, R. Crime and punishment.Nature 436, 636–637 (2005). https://doi.org/10.1038/436636a

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