Development of inducible EIAV-based lentiviral vector packaging and producer cell lines (original) (raw)
Mazarakis ND, Azzouz M, Rohll JB, Ellard FM, Wilkes FJ, Olsen AL et al. Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery. Hum Mol Genet 2001; 10: 2109–2121. ArticleCASPubMed Google Scholar
Mitrophanous K, Yoon S, Rohll J, Patil D, Wilkes F, Kim V et al. Stable gene transfer to the nervous system using a non-primate lentiviral vector. Gene Therapy 1999; 6: 1808–1818. ArticleCASPubMed Google Scholar
Mselli-Lakhal L, Guiguen F, Greenland T, Mornex JF, Chebloune Y . Gene transfer system derived from the caprine arthritis-encephalitis lentivirus. J Virol Methods 2006; 136: 177–184. ArticleCASPubMed Google Scholar
Poeschla EM, Wong-Staal F, Looney DJ . Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors. Nat Med 1998; 4: 354–357. ArticleCASPubMed Google Scholar
Takahashi K, Luo T, Saishin Y, Saishin Y, Sung J, Hackett S et al. Sustained transduction of ocular cells with a bovine immunodeficiency viral vector. Hum Gene Ther 2002; 13: 1305–1316. ArticleCASPubMed Google Scholar
Azzouz M, Martin-Rendon E, Barber RD, Mitrophanous KA, Carter EE, Rohll JB et al. Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease. J Neurosci 2002; 22: 10302–10312. ArticleCASPubMedPubMed Central Google Scholar
Azzouz M, Mazarakis N . Non-primate EIAV-based lentiviral vectors as gene delivery system for motor neuron diseases. Curr Gene Ther 2004; 4: 277–286. ArticleCASPubMed Google Scholar
Azzouz M, Ralph S, Wong LF, Day D, Askham Z, Barber RD et al. Neuroprotection in a rat Parkinson model by GDNF gene therapy using EIAV vector. Neuroreport 2004; 15: 985–990. ArticleCASPubMed Google Scholar
Balaggan KS, Binley K, Esapa M, MacLaren RE, Iqball S, Duran Y et al. EIAV vector-mediated delivery of endostatin or angiostatin inhibits angiogenesis and vascular hyperpermeability in experimental CNV. Gene Therapy 2006; 13: 1153–1165. ArticleCASPubMed Google Scholar
Bienemann AS, Martin-Rendon E, Cosgrave AS, Glover CP, Wong LF, Kingsman SM et al. Long-term replacement of a mutated nonfunctional CNS gene: reversal of hypothalamic diabetes insipidus using an EIAV-based lentiviral vector expressing arginine vasopressin. Mol Ther 2003; 7: 588–596. ArticleCASPubMed Google Scholar
Kong J, Kim SR, Binley K, Pata I, Doi K, Mannik J et al. Correction of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapy. Gene Therapy 2008; 15: 1311–1320. ArticleCASPubMedPubMed Central Google Scholar
Radcliffe PA, Sion CJ, Wilkes FJ, Custard EJ, Beard GL, Kingsman SM et al. Analysis of factor VIII mediated suppression of lentiviral vector titres. Gene Therapy 2008; 15: 289–297. ArticleCASPubMed Google Scholar
Ralph GS, Binley K, Wong LF, Azzouz M, Mazarakis ND . Gene therapy for neurodegenerative and ocular diseases using lentiviral vectors. Clin Sci (Lond) 2006; 110: 37–46. ArticleCAS Google Scholar
Broussau S, Jabbour N, Lachapelle G, Durocher Y, Tom R, Transfiguracion J et al. Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture. Mol Ther 2008; 16: 500–507. ArticleCASPubMed Google Scholar
Cockrell AS, Ma H, Fu K, McCown TJ, Kafri T . A trans-lentiviral packaging cell line for high-titer conditional self-inactivating HIV-1 vectors. Mol Ther 2006; 14: 276–284. ArticleCASPubMed Google Scholar
Farson D, Witt R, McGuinness R, Dull T, Kelly M, Song J et al. A new-generation stable inducible packaging cell line for lentiviral vectors. Hum Gene Ther 2001; 12: 981–997. ArticleCASPubMed Google Scholar
Ikeda Y, Takeuchi Y, Martin F, Cosset FL, Mitrophanous K, Collins M . Continuous high-titer HIV-1 vector production. Nat Biotechnol 2003; 21: 569–572. ArticleCASPubMed Google Scholar
Kafri T, van Praag H, Ouyang L, Gage FH, Verma IM . A packaging cell line for lentivirus vectors. J Virol 1999; 73: 576–584. CASPubMedPubMed Central Google Scholar
Kaul M, Yu H, Ron Y, Dougherty JP . Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences. Virology 1998; 249: 167–174. ArticleCASPubMed Google Scholar
Klages N, Zufferey R, Trono D . A stable system for the high-titer production of multiply attenuated lentiviral vectors. Mol Ther 2000; 2: 170–176. ArticleCASPubMed Google Scholar
Ni Y, Sun S, Oparaocha I, Humeau L, Davis B, Cohen R et al. Generation of a packaging cell line for prolonged large-scale production of high-titer HIV-1-based lentiviral vector. J Gene Med 2005; 7: 818–834. ArticleCASPubMed Google Scholar
Pacchia AL, Adelson ME, Kaul M, Ron Y, Dougherty JP . An inducible packaging cell system for safe, efficient lentiviral vector production in the absence of HIV-1 accessory proteins. Virology 2001; 282: 77–86. ArticleCASPubMed Google Scholar
Sparacio S, Pfeiffer T, Schaal H, Bosch V . Generation of a flexible cell line with regulatable, high-level expression of HIV Gag/Pol particles capable of packaging HIV-derived vectors. Mol Ther 2001; 3: 602–612. ArticleCASPubMed Google Scholar
Xu K, Ma H, McCown TJ, Verma IM, Kafri T . Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors. Mol Ther 2001; 3: 97–104. ArticleCASPubMed Google Scholar
Yu H, Rabson AB, Kaul M, Ron Y, Dougherty JP . Inducible human immunodeficiency virus type 1 packaging cell lines. J Virol 1996; 70: 4530–4537. CASPubMedPubMed Central Google Scholar
Burns JC, Friedmann T, Driever W, Burrascano M, Yee JK . Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc Natl Acad Sci USA 1993; 90: 8033–8037. ArticleCASPubMedPubMed Central Google Scholar
DePolo NJ, Reed JD, Sheridan PL, Townsend K, Sauter SL, Jolly DJ et al. VSV-G pseudotyped lentiviral vector particles produced in human cells are inactivated by human serum. Mol Ther 2000; 2: 218–222. ArticleCASPubMed Google Scholar
Yee JK, Miyanohara A, LaPorte P, Bouic K, Burns JC, Friedmann T . A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes. Proc Natl Acad Sci USA 1994; 91: 9564–9568. ArticleCASPubMedPubMed Central Google Scholar
Gossen M, Bujard H . Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992; 89: 5547–5551. ArticleCASPubMedPubMed Central Google Scholar
Shockett P, Difilippantonio M, Hellman N, Schatz DG . A modified tetracycline-regulated system provides autoregulatory, inducible gene expression in cultured cells and transgenic mice. Proc Natl Acad Sci USA 1995; 92: 6522–6526. ArticleCASPubMedPubMed Central Google Scholar
Yao F, Svensjo T, Winkler T, Lu M, Eriksson C, Eriksson E . Tetracycline repressor, tetR, rather than the tetR-mammalian cell transcription factor fusion derivatives, regulates inducible gene expression in mammalian cells. Hum Gene Ther 1998; 9: 1939–1950. ArticleCASPubMed Google Scholar
Hillen W, Berens C . Mechanisms underlying expression of Tn10 encoded tetracycline resistance. Annu Rev Microbiol 1994; 48: 345–369. ArticleCASPubMed Google Scholar
Carrondo MJ, Merten OW, Haury M, Alves PM, Coroadinha AS . Impact of retroviral vector components stoichiometry on packaging cell lines: effects on productivity and vector quality. Hum Gene Ther 2008; 19: 199–210. ArticleCASPubMed Google Scholar
Yap MW, Kingsman SM, Kingsman AJ . Effects of stoichiometry of retroviral components on virus production. J Gen Virol 2000; 81: 2195–2202. ArticleCASPubMed Google Scholar
Farley DC, Iqball S, Smith JC, Miskin JE, Kingsman SM, Mitrophanous KA . Factors that influence VSV-G pseudotyping and transduction efficiency of lentiviral vectors-in vitro and in vivo implications. J Gene Med 2007; 9: 345–356. ArticleCASPubMed Google Scholar
McGrew MJ, Sherman A, Ellard FM, Lillico SG, Gilhooley HJ, Kingsman AJ et al. Efficient production of germline transgenic chickens using lentiviral vectors. EMBO Rep 2004; 5: 728–733. ArticleCASPubMedPubMed Central Google Scholar
Rohll JB, Mitrophanous KA, Martin-Rendon E, Ellard FM, Radcliffe PA, Mazarakis ND et al. Design, production, safety, evaluation, and clinical applications of nonprimate lentiviral vectors. Methods Enzymol 2002; 346: 466–500. ArticleCASPubMed Google Scholar
Miskin J, Chipchase D, Rohll J, Beard G, Wardell T, Angell D et al. A replication competent lentivirus (RCL) assay for equine infectious anaemia virus (EIAV)-based lentiviral vectors. Gene Therapy 2006; 13: 196–205. ArticleCASPubMed Google Scholar