The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin (original) (raw)
References
Saltiel, A. R. & Kahn, C. R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature414, 799–806 (2001) ArticleADSCAS Google Scholar
Bryant, N. J., Govers, R. & James, D. E. Regulated transport of the glucose transporter GLUT4. Nature Rev. Mol. Cell Biol.3, 267–277 (2002) ArticleCAS Google Scholar
Chiang, S. H. et al. Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10. Nature410, 944–948 (2001) ArticleADSCAS Google Scholar
Liu, J., Kimura, A., Baumann, C. A. & Saltiel, A. R. APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes. Mol. Cell. Biol.22, 3599–3609 (2002) ArticleCAS Google Scholar
Neudauer, C. L., Joberty, G., Tatsis, N. & Macara, I. G. Distinct cellular effects and interactions of the Rho-family GTPase TC10. Curr. Biol.8, 1151–1160 (1998) ArticleCAS Google Scholar
TerBush, D. R., Maurice, T., Roth, D. & Novick, P. The exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J.15, 6483–6494 (1996) ArticleCAS Google Scholar
Kee, Y. et al. Subunit structure of the mammalian exocyst complex. Proc. Natl Acad. Sci. USA94, 14438–14443 (1997) ArticleADSCAS Google Scholar
Symons, M. Rho family GTPases: the cytoskeleton and beyond. Trends Biochem. Sci.21, 178–181 (1996) ArticleCAS Google Scholar
Tapon, N. & Hall, A. Rho, Rac, and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr. Opin. Cell Biol.9, 86–92 (1997) ArticleCAS Google Scholar
Van Aelst, L. & D'Souza-Schorey, C. Rho GTPases and signaling networks. Genes Dev.11, 2295–2322 (1997) ArticleCAS Google Scholar
Chiang, S. H., Hou, J. C., Hwang, J., Pessin, J. E. & Saltiel, A. R. Cloning and functional characterization of related TC10 isoforms, a subfamily of Rho proteins involved in insulin-stimulated glucose transport. J. Biol. Chem.277, 13067–13073 (2002) ArticleCAS Google Scholar
Hsu, S. C., Hazuka, C. D., Foletti, D. L. & Scheller, R. H. Targeting vesicles to specific sites on the plasma membrane: the role of the sec6/8 complex. Trends Cell. Biol.9, 150–153 (1999) ArticleCAS Google Scholar
Guo, W., Sacher, M., Barrowman, J., Ferro-Novick, S. & Novick, P. Protein complexes in transport vesicle targeting. Trends Cell Biol.10, 251–255 (2000) ArticleCAS Google Scholar
Lipschutz, J. H. & Mostov, K. E. Exocytosis: the many masters of the exocyst. Curr. Biol.12, R212–R214 (2002) ArticleCAS Google Scholar
Ting, A. E. et al. rSec6 and rSec8, mammalian homologs of yeast proteins essential for secretion. Proc. Natl Acad. Sci. USA92, 9613–9617 (1995) ArticleADSCAS Google Scholar
Yeaman, C., Grindstaff, K. K., Wright, J. R. & Nelson, W. J. Sec6/8 complexes on trans-Golgi network and plasma membrane regulate late stages of exocytosis in mammalian cells. J. Cell Biol.155, 593–604 (2001) ArticleCAS Google Scholar
Kimura, A., Baumann, C. A., Chiang, S. H. & Saltiel, A. R. The sorbin homology domain: a motif for the targeting of proteins to lipid rafts. Proc. Natl Acad. Sci. USA98, 9098–9103 (2001) ArticleADSCAS Google Scholar
Dawson, K., Aviles-Hernandez, A., Cushman, S. W. & Malide, D. Insulin-regulated trafficking of dual-labelled glucose transporter 4 in primary rat adipose cells. Biochem. Biophys. Res. Commun.287, 445–454 (2001) ArticleCAS Google Scholar
Novick, P. & Guo, W. Ras family therapy: Rab, Rho and Ral talk to the exocyst. Trends Cell Biol.12, 247–249 (2002) ArticleCAS Google Scholar
Cheatham, B. GLUT4 and company: SNAREing roles in insulin-regulated glucose uptake. Trends Endocrinol. Metab.11, 356–361 (2000) ArticleCAS Google Scholar
Chamberlain, L. H. & Gould, G. W. The v-and t-SNARE proteins that mediate Glut4 vesicle fusion are localised in detergent-insoluble lipid rafts present on distinct intracellular membranes. J. Biol. Chem.277, 49750–49754 (2002) ArticleCAS Google Scholar
Sherman, L. A., Hirshman, M. F., Cormont, M., Le Marchand-Brustel, Y. & Goodyear, L. J. Differential effects of insulin and exercise on Rab4 distribution in rat skeletal muscle. Endocrinology137, 266–273 (1996) ArticleCAS Google Scholar
Cormont, M. et al. Potential role of Rab4 in the regulation of subcellular localization of Glut4 in adipocytes. Mol. Cell. Biol.16, 6879–6886 (1996) ArticleCAS Google Scholar
Shisheva, A. & Czech, M. P. Association of cytosolic Rab4 with GDI isoforms in insulin-sensitive 3T3-L1 adipocytes. Biochemistry36, 6564–6570 (1997) ArticleCAS Google Scholar
Millar, C. A., Shewan, A., Hickson, G. R., James, D. E. & Gould, G. W. Differential regulation of secretory compartments containing the insulin-responsive glucose transporter 4 in 3T3-L1 adipocytes. Mol. Biol. Cell10, 3675–3688 (1999) ArticleCAS Google Scholar
Chang, L., Adams, R. D. & Saltiel, A. R. The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes. Proc. Natl Acad. Sci. USA99, 12835–12840 (2002) ArticleADSCAS Google Scholar
Lin, D. et al. A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity. Nature Cell Biol.2, 540–547 (2000) ArticleCAS Google Scholar
Thurmond, D. C. et al. Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes. J. Biol. Chem.273, 33876–33883 (1998) ArticleCAS Google Scholar
Hwang, J. B. & Frost, S. C. Effect of alternative glycosylation on insulin receptor processing. J. Biol. Chem.274, 22813–22820 (1999) ArticleCAS Google Scholar