X-ray structure of a voltage-dependent K+ channel (original) (raw)
References
Hille, B. Ion Channels of Excitable Membranes (Sinauer, Sunderland, Massachusetts, 2001) Google Scholar
Hodgkin, A. L. & Huxley, A. F. A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. (Lond.)117, 500–544 (1952) ArticleCAS Google Scholar
Armstrong, C. M. & Bezanilla, F. Charge movement associated with the opening and closing of the activation gates of the Na+ channels. J. Gen. Physiol.63, 533–552 (1974) ArticleCAS Google Scholar
Sigworth, F. J. Voltage gating of ion channels. Q. Rev. Biophys.27, 1–40 (1994) ArticleCAS Google Scholar
Bezanilla, F. The voltage sensor in voltage-dependent ion channels. Physiol. Rev.80, 555–592 (2000) ArticleCAS Google Scholar
Schoppa, N. E., McCormack, K., Tanouye, M. A. & Sigworth, F. J. The size of gating charge in wild-type and mutant Shaker potassium channels. Science255, 1712–1715 (1992) ArticleADSCAS Google Scholar
Seoh, S. A., Sigg, D., Papazian, D. M. & Bezanilla, F. Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel. Neuron16, 1159–1167 (1996) ArticleCAS Google Scholar
Aggarwal, S. K. & MacKinnon, R. Contribution of the S4 segment to gating charge in the Shaker K+ channel. Neuron16, 1169–1177 (1996) ArticleCAS Google Scholar
Noda, M. et al. Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence. Nature312, 121–127 (1984) ArticleADSCAS Google Scholar
Tanabe, T. et al. Primary structure of the receptor for calcium channel blockers from skeletal muscle. Nature328, 313–318 (1987) ArticleADSCAS Google Scholar
Tempel, B. L., Papazian, D. M., Schwarz, T. L., Jan, L. Y. & Jan, Y. N. Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila. Science237, 770–775 (1987) ArticleADSCAS Google Scholar
Yang, N. & Horn, R. Evidence for voltage-dependent S4 movement in sodium channels. Neuron15, 213–218 (1995) ArticleCAS Google Scholar
Larsson, H. P., Baker, O. S., Dhillon, D. S. & Isacoff, E. Y. Transmembrane movement of the Shaker K+ channel S4. Neuron16, 387–397 (1996) ArticleCAS Google Scholar
Yusaf, S. P., Wray, D. & Sivaprasadarao, A. Measurement of the movement of the S4 segment during the activation of a voltage-gated potassium channel. Pflugers Arch.433, 91–97 (1996) ArticleCAS Google Scholar
Baker, O. S., Larsson, H. P., Mannuzzu, L. M. & Isacoff, E. Y. Three transmembrane conformations and sequence-dependent displacement of the S4 domain in Shaker K+ channel gating. Neuron20, 1283–1294 (1998) ArticleCAS Google Scholar
Mannuzzu, L. M., Moronne, M. M. & Isacoff, E. Y. Direct physical measure of conformational rearrangement underlying potassium channel gating. Science271, 213–216 (1996) ArticleADSCAS Google Scholar
Cha, A. & Bezanilla, F. Characterizing voltage-dependent conformational changes in the Shaker K+ channel with fluorescence. Neuron19, 1127–1140 (1997) ArticleCAS Google Scholar
Horn, R. Coupled movements in voltage-gated ion channels. J. Gen. Physiol.120, 449–453 (2002) ArticleCAS Google Scholar
Gandhi, C. S. & Isacoff, E. Y. Molecular models of voltage sensing. J. Gen. Physiol.120, 455–463 (2002) ArticleCAS Google Scholar
Bezanilla, F. Voltage sensor movements. J. Gen. Physiol.120, 465–473 (2002) ArticleCAS Google Scholar
Ruta, V., Jiang, Y., Lee, A., Chen, J. & MacKinnon, R. Functional analysis of an archaebacterial voltage-dependent K+ channel. Nature422, 180–185; advance online publication, 2 March 2003 (doi:10.1038/nature01473)
Jiang, Y., Ruta, V., Chen, J., Lee, A. & MacKinnon, R. The principle of gating charge movement in a voltage-dependent K+ channel. Nature423, 42–48 (2003) ArticleADSCAS Google Scholar
Doyle, D. A. et al. The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science280, 69–77 (1998) ArticleADSCAS Google Scholar
Zhou, Y., Morais-Cabral, J. H., Kaufman, A. & MacKinnon, R. Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution. Nature414, 43–48 (2001) ArticleADSCAS Google Scholar
Jiang, Y. et al. Crystal structure and mechanism of a calcium-gated potassium channel. Nature417, 515–522 (2002) ArticleADSCAS Google Scholar
Jiang, Y. et al. The open pore conformation of potassium channels. Nature417, 523–526 (2002) ArticleADSCAS Google Scholar
Swartz, K. J. & MacKinnon, R. Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels. Neuron18, 675–682 (1997) ArticleCAS Google Scholar
Swartz, K. J. & MacKinnon, R. Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites. Neuron18, 665–673 (1997) ArticleCAS Google Scholar
Lu, Z., Klem, A. M. & Ramu, Y. Ion conduction pore is conserved among potassium channels. Nature413, 809–813 (2001) ArticleADSCAS Google Scholar
Santacruz-Toloza, L., Huang, Y., John, S. A. & Papazian, D. M. Glycosylation of Shaker potassium channel protein in insect cell culture and in Xenopus oocytes. Biochemistry33, 5607–5613 (1994) ArticleCAS Google Scholar
Blaustein, R. O., Cole, P. A., Williams, C. & Miller, C. Tethered blockers as molecular ‘tape measures’ for a voltage-gated K+ channel. Nature Struct. Biol.7, 309–311 (2000) ArticleCAS Google Scholar
Slatin, S. L., Qiu, X. Q., Jakes, K. S. & Finkelstein, A. Identification of a translocated protein segment in a voltage-dependent channel. Nature371, 158–161 (1994) ArticleADSCAS Google Scholar
Qiu, X. Q., Jakes, K. S., Kienker, P. K., Finkelstein, A. & Slatin, S. L. Major transmembrane movement associated with colicin Ia channel gating. J. Gen. Physiol.107, 313–328 (1996) ArticleCAS Google Scholar
Harlow, E. & Lane, D. Antibodies: A Laboratory Manual (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, 1989) Google Scholar
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol.276, 307–326 (1997) ArticleCAS Google Scholar
Collaborative Computational Project, N.4 The CCP4 suite: programs for X-ray crystallography. Acta Crystallogr. D50, 760–763 (1994) Article Google Scholar
Navaza, J. AMoRe: an automated package for molecular replacement. Acta Crystallogr. A50, 157–163 (1994) Article Google Scholar
Brunger, A. T., Leahy, D. J., Hynes, T. R. & Fox, R. O. 2.9 Å resolution structure of an anti-dinitrophenyl-spin-label monoclonal antibody Fab fragment with bound hapten. J. Mol. Biol.221, 239–256 (1991) CASPubMed Google Scholar
Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A47, 110–119 (1991) Article Google Scholar
Brunger, A. T. et al. Crystallography & NMR System: a new software suite for macromolecular structure determination. Acta Crystallogr. D54, 905–921 (1998) ArticleCAS Google Scholar
Heginbotham, L., LeMasurier, M., Kolmakova-Partensky, L. & Miller, C. Single Streptomyces lividans K+ channels. Functional asymmetries and sidedness of proton activation. J. Gen. Physiol.114, 551–560 (1999) ArticleCAS Google Scholar
Thompson, J. D., Higgins, D. G. & Gibson, T. J. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. Nucleic Acids Res.22, 4673–4680 (1994) ArticleCAS Google Scholar