Dissecting self-renewal in stem cells with RNA interference (original) (raw)
Smith, A. G. Embryo-derived stem cells: of mice and men. Annu. Rev. Cell Dev. Biol.17, 435–462 (2001) ArticleCAS Google Scholar
Nichols, J. et al. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell95, 379–391 (1998) ArticleCAS Google Scholar
Niwa, H., Miyazaki, J. & Smith, A. G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nature Genet.24, 372–376 (2000) ArticleCAS Google Scholar
Chambers, I. et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell113, 643–655 (2003) ArticleCAS Google Scholar
Mitsui, K. et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell113, 631–642 (2003) ArticleCAS Google Scholar
Niwa, H., Burdon, T., Chambers, I. & Smith, A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev.12, 2048–2060 (1998) ArticleCAS Google Scholar
Ying, Q. L., Nichols, J., Chambers, I. & Smith, A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell115, 281–292 (2003) ArticleCAS Google Scholar
Burdon, T., Stracey, C., Chambers, I., Nichols, J. & Smith, A. Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells. Dev. Biol.210, 30–43 (1999) ArticleCAS Google Scholar
Sato, N., Meijer, L., Skaltsounis, L., Greengard, P. & Brivanlou, A. H. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nature Med.10, 55–63 (2004) ArticleCAS Google Scholar
Loebel, D. A., Watson, C. M., De Young, R. A. & Tam, P. P. Lineage choice and differentiation in mouse embryos and embryonic stem cells. Dev. Biol.264, 1–14 (2003) ArticleCAS Google Scholar
Bortvin, A. et al. Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei. Development130, 1673–1680 (2003) ArticleCAS Google Scholar
Tighe, A. P. & Gudas, L. J. Retinoic acid inhibits leukemia inhibitory factor signaling pathways in mouse embryonic stem cells. J. Cell. Physiol.198, 223–229 (2004) ArticleCAS Google Scholar
Burdon, T., Smith, A. & Savatier, P. Signalling, cell cycle and pluripotency in embryonic stem cells. Trends Cell Biol.12, 432–438 (2002) ArticleCAS Google Scholar
Avilion, A. A. et al. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev.17, 126–140 (2003) ArticleCAS Google Scholar
Bamshad, M. et al. Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. Nature Genet.16, 311–315 (1997) ArticleCAS Google Scholar
Mitsunaga, K. et al. Loss of PGC-specific expression of the orphan nuclear receptor ERR-β results in reduction of germ cell number in mouse embryos. Mech. Dev.121, 237–246 (2004) ArticleCAS Google Scholar
Pekarsky, Y. et al. Tcl1 enhances Akt kinase activity and mediates its nuclear translocation. Proc. Natl Acad. Sci. USA97, 3028–3033 (2000) ArticleADSCAS Google Scholar
Ting, D. T., Kyba, M. & Daley, G. Q. Inducible transgene expression in mouse stem cells. Methods Mol. Med.105, 23–46 (2005) CASPubMed Google Scholar
Yasunaga, M. et al. Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells. Nature Biotechnol.23, 1542–1550 (2005) ArticleCAS Google Scholar
Corson, L. B., Yamanaka, Y., Lai, K. M. & Rossant, J. Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development130, 4527–4537 (2003) ArticleCAS Google Scholar
Saba-El-Leil, M. K. et al. An essential function of the mitogen-activated protein kinase Erk2 in mouse trophoblast development. EMBO Rep.4, 964–968 (2003) ArticleCAS Google Scholar
Keller, G. Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev.19, 1129–1155 (2005) ArticleCAS Google Scholar
Ferri, A. L. et al. Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development131, 3805–3819 (2004) ArticleCAS Google Scholar
Boyer, L. A. et al. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell122, 947–956 (2005) ArticleCAS Google Scholar
Kurokawa, D. et al. Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development131, 3307–3317 (2004) ArticleCAS Google Scholar
Essner, J. J., Branford, W. W., Zhang, J. & Yost, H. J. Mesendoderm and left-right brain, heart and gut development are differentially regulated by pitx2 isoforms. Development127, 1081–1093 (2000) CASPubMed Google Scholar
Evans, A. L. & Gage, P. J. Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development. Hum. Mol. Genet.14, 3347–3359 (2005) ArticleCAS Google Scholar
Zhang, C., Basta, T. & Klymkowsky, M. W. SOX7 and SOX18 are essential for cardiogenesis in Xenopus. Dev. Dyn.234, 878–891 (2005) ArticleCAS Google Scholar
Loh, Y. H. et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nature Genet.38, 431–440 (2006) ArticleCAS Google Scholar
Luo, J. et al. Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-β. Nature388, 778–782 (1997) ArticleADSCAS Google Scholar
Davenport, T. G., Jerome-Majewska, L. A. & Papaioannou, V. E. Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome. Development130, 2263–2273 (2003) ArticleCAS Google Scholar
Kang, S. M. et al. Impaired T- and B-cell development in Tcl1-deficient mice. Blood105, 1288–1294 (2005) ArticleCAS Google Scholar
Narducci, M. G. et al. TCL1 participates in early embryonic development and is overexpressed in human seminomas. Proc. Natl Acad. Sci. USA99, 11712–11717 (2002) ArticleADSCAS Google Scholar
Berns, K. et al. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature428, 431–437 (2004) ArticleADSCAS Google Scholar
Paddison, P. J. et al. A resource for large-scale RNA-interference-based screens in mammals. Nature428, 427–431 (2004) ArticleADSCAS Google Scholar
Rao, M. Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells. Dev. Biol.275, 269–286 (2004) ArticleCAS Google Scholar