Orai1 is an essential pore subunit of the CRAC channel (original) (raw)
Parekh, A. B. & Putney, J. W. Jr. Store-operated calcium channels. Physiol. Rev.85, 757–810 (2005) ArticleCAS Google Scholar
Lewis, R. S. Calcium signalling mechanisms in T lymphocytes. Annu. Rev. Immunol.19, 497–521 (2001) ArticleCAS Google Scholar
Roos, J. et al. STIM1, an essential and conserved component of store-operated Ca2+ channel function. J. Cell Biol.169, 435–445 (2005) ArticleCAS Google Scholar
Zhang, S. L. et al. STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane. Nature437, 902–905 (2005) ArticleADSCAS Google Scholar
Liou, J. et al. STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx. Curr. Biol.15, 1235–1241 (2005) ArticleCAS Google Scholar
Feske, S. et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature441, 179–185 (2006) ArticleADSCAS Google Scholar
Vig, M. et al. CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry. Science312, 1220–1223 (2006) ArticleADSCAS Google Scholar
Zhang, S. L. et al. Genome-wide RNAi screen of Ca2+ influx identifies genes that regulate Ca2+ release-activated Ca2+ channel activity. Proc. Natl Acad. Sci. USA103, 9357–9362 (2006) ArticleADSCAS Google Scholar
Peinelt, C. et al. Amplification of CRAC current by STIM1 and CRACM1 (Orai1). Nature Cell Biol.8, 771–773 (2006) ArticleCAS Google Scholar
Soboloff, J. et al. Orai1 and STIM reconstitute store-operated calcium channel function. J. Biol. Chem.281, 20661–20665 (2006) ArticleCAS Google Scholar
Mercer, J. C. et al. Large store-operated calcium-selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. J. Biol. Chem. doi:10.1074/jbc.M604589200 (published online 28 June 2006)
Sather, W. A. & McCleskey, E. W. Permeation and selectivity in calcium channels. Annu. Rev. Physiol.65, 133–159 (2003) ArticleCAS Google Scholar
Owsianik, G., Talavera, K., Voets, T. & Nilius, B. Permeation and selectivity of TRP channels. Annu. Rev. Physiol.68, 685–717 (2006) ArticleCAS Google Scholar
Feske, S., Prakriya, M., Rao, A. & Lewis, R. S. A severe defect in CRAC Ca2+ channel activation and altered K+ channel gating in T cells from immunodeficient patients. J. Exp. Med.202, 651–662 (2005) ArticleCAS Google Scholar
Zweifach, A. & Lewis, R. S. Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores. Proc. Natl Acad. Sci. USA90, 6295–6299 (1993) ArticleADSCAS Google Scholar
Hoth, M. & Penner, R. Calcium release-activated calcium current in rat mast cells. J. Physiol. (Lond.)465, 359–386 (1993) ArticleCAS Google Scholar
Bakowski, D. & Parekh, A. B. Monovalent cation permeability and Ca2+ block of the store-operated Ca2+ current ICRAC in rat basophilic leukemia cells. Pflugers Arch.443, 892–902 (2002) ArticleCAS Google Scholar
Lepple-Wienhues, A. & Cahalan, M. D. Conductance and permeation of monovalent cations through depletion-activated Ca2+ channels (ICRAC) in Jurkat T cells. Biophys. J.71, 787–794 (1996) ArticleCAS Google Scholar
Prakriya, M. & Lewis, R. S. Separation and characterization of currents through store-operated CRAC channels and Mg2+-inhibited cation (MIC) channels. J. Gen. Physiol.119, 487–507 (2002) ArticleCAS Google Scholar
Su, Z., Shoemaker, R. L., Marchase, R. B. & Blalock, J. E. Ca2+ modulation of Ca2+ release-activated Ca2+ channels is responsible for the inactivation of its monovalent cation current. Biophys. J.86, 805–814 (2004) ArticleADSCAS Google Scholar
Prakriya, M. & Lewis, R. S. Regulation of CRAC channel activity by recruitment of silent channels to a high open-probability gating mode. J. Gen. Physiol. (in the press)
Voets, T. et al. CaT1 and the calcium release-activated calcium channel manifest distinct pore properties. J. Biol. Chem.276, 47767–47770 (2001) ArticleCAS Google Scholar
Yang, J., Ellinor, P. T., Sather, W. A., Zhang, J. F. & Tsien, R. W. Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels. Nature366, 158–161 (1993) ArticleADSCAS Google Scholar
Ellinor, P. T., Yang, J., Sather, W. A., Zhang, J. F. & Tsien, R. W. Ca2+ channel selectivity at a single locus for high-affinity Ca2+ interactions. Neuron15, 1121–1132 (1995) ArticleCAS Google Scholar
Voets, T., Janssens, A., Prenen, J., Droogmans, G. & Nilius, B. Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6. J. Gen. Physiol.121, 245–260 (2003) ArticleCAS Google Scholar
Voets, T., Janssens, A., Droogmans, G. & Nilius, B. Outer pore architecture of a Ca2+-selective TRP channel. J. Biol. Chem.279, 15223–15230 (2004) ArticleCAS Google Scholar
Eisenberg, B. Proteins, channels and crowded ions. Biophys. Chem.100, 507–517 (2003) ArticleCAS Google Scholar
Corry, B. & Chung, S. H. Mechanisms of valence selectivity in biological ion channels. Cell. Mol. Life Sci.63, 301–315 (2006) ArticleCAS Google Scholar
Feske, S., Giltnane, J., Dolmetsch, R., Staudt, L. & Rao, A. Gene regulation by calcium influx in T lymphocytes. Nature Immunol.2, 316–324 (2001) ArticleCAS Google Scholar
Yeromin, A. V. et al. Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature advance online publication, doi:10.1038/nature05108 (20 August 2006).