Taking dendritic cells into medicine (original) (raw)

• Steinman, R. M. & Cohn, Z. A. Identification of a novel cell type in peripheral lymphoid organs of mice. I. Morphology, quantitation, tissue distribution. J. Exp. Med. 137, 1142–1162 (1973)
  CAS PubMed PubMed Central Google Scholar
• Banchereau, J. & Steinman, R. M. Dendritic cells and the control of immunity. Nature 392, 245–252 (1998)
  ADS CAS PubMed Google Scholar
• Janeway, C. A. & Medzhitov, R. Innate immune recognition. Annu. Rev. Immunol. 20, 197–216 (2002)
  CAS PubMed Google Scholar
• Guermonprez, P., Valladeau, J., Zitvogel, L., Thery, C. & Amigorena, S. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 20, 621–667 (2002)
  CAS PubMed Google Scholar
• Trombetta, E. S. & Mellman, I. Cell biology of antigen processing in vitro and in vivo. Annu. Rev. Immunol. 23, 975–1028 (2005)
  CAS PubMed Google Scholar
• Cyster, J. G. Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs. J. Exp. Med. 189, 447–450 (1999)
  CAS PubMed PubMed Central Google Scholar
• Itano, A. A. & Jenkins, M. K. Antigen presentation to naive CD4 T cells in the lymph node. Nature Immunol. 4, 733–739 (2003)
  CAS Google Scholar
• Randolph, G. J., Angeli, V. & Swartz, M. A. Dendritic-cell trafficking to lymph nodes through lymphatic vessels. Nature Rev. Immunol. 5, 617–628 (2005)
  CAS Google Scholar
• Hawiger, D. et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J. Exp. Med. 194, 769–780 (2001)
  CAS PubMed PubMed Central Google Scholar
• Probst, H. C., McCoy, K., Okazaki, T., Honjo, T. & van den Broek, M. Resting dendritic cells induce peripheral CD8+ T cell tolerance through PD-1 and CTLA-4. Nature Immunol. 6, 280–286 (2005)
  CAS Google Scholar
• Luo, X. et al. Dendritic cells with TGF-β1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells. Proc. Natl Acad. Sci. USA 104, 2821–2826 (2007)
  ADS CAS PubMed PubMed Central Google Scholar
• Pulendran, B. et al. Distinct dendritic cell subsets differentially regulate the class of immune responses in vivo. Proc. Natl Acad. Sci. USA 96, 1036–1041 (1999)
  ADS CAS PubMed PubMed Central Google Scholar
• Maldonado-Lopez, R. et al. CD8α+ and CD8α- subclasses of dendritic cells direct the development of distinct T helper cells in vivo. J. Exp. Med. 189, 587–592 (1999)
  CAS PubMed PubMed Central Google Scholar
• Napolitani, G., Rinaldi, A., Bertoni, F., Sallusto, F. & Lanzavecchia, A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nature Immunol. 6, 769–776 (2005)
  CAS Google Scholar
• Seder, R. A., Paul, W. E., Davis, M. M., Fazekas de St & Groth, B. The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. J. Exp. Med. 176, 1091–1098 (1992)
  CAS PubMed Google Scholar
• Leibundgut-Landmann, S. et al. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nature Immunol. 8, 630–638 (2007)
  CAS Google Scholar
• Jonuleit, H., Schmitt, E., Schuler, G., Knop, J. & Enk, A. H. Induction of interleukin 10-producing, nonproliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J. Exp. Med. 192, 1213–1222 (2000)
  CAS PubMed PubMed Central Google Scholar
• Badovinac, V. P., Messingham, K. A., Jabbari, A., Haring, J. S. & Harty, J. T. Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination. Nature Med. 11, 748–756 (2005)
  CAS PubMed Google Scholar
• Trumpfheller, C. et al. Intensified and protective CD4+ T cell immunity at a mucosal surface after a single dose of anti-dendritic cell HIV gag fusion antibody vaccine. J. Exp. Med. 203, 607–617 (2006)
  CAS PubMed PubMed Central Google Scholar
• Huang, F.-P. et al. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med. 191, 435–442 (2000)
  CAS PubMed PubMed Central Google Scholar
• Niess, J. H. et al. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307, 254–258 (2005)
  Article ADS CAS PubMed Google Scholar
• Lindquist, R. L. et al. Visualizing dendritic cell networks in vivo. Nature Immunol. 5, 1243–1250 (2004)
  CAS Google Scholar
• Reis e Sousa, C. Dendritic cells in a mature age. Nature Rev. Immunol. 6, 476–483 (2006)
  CAS Google Scholar
• Dudziak, D. et al. Differential antigen processing by dendritic cell subsets in vivo. Science 315, 107–111 (2007)
  ADS CAS PubMed Google Scholar
• Shortman, K. & Naik, S. H. Steady-state and inflammatory dendritic-cell development. Nature Rev. Immunol. 7, 19–30 (2007)
  CAS Google Scholar
• Dalod, M. et al. Interferon α/β and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo.. J. Exp. Med. 195, 517–528 (2002)
  CAS PubMed PubMed Central Google Scholar
• Probst, H. C. & van den Broek, M. Priming of CTLs by lymphocytic choriomeningitis virus depends on dendritic cells. J. Immunol. 174, 3920–3924 (2005)
  CAS PubMed Google Scholar
• Figdor, C. G., van Kooyk, Y. & Adema, G. J. C-type lectin receptors on dendritic cells and Langerhans cells. Nature Rev. Immunol. 2, 77–84 (2002)
  CAS Google Scholar
• Gautier, G. et al. A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J. Exp. Med. 201, 1435–1446 (2005)
  CAS PubMed PubMed Central Google Scholar
• Fritz, J. H. et al. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity 26, 445–459 (2007)
  CAS PubMed Google Scholar
• Coutanceau, E. et al. Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone. J. Exp. Med. 204, 1395–1403 (2007)
  CAS PubMed PubMed Central Google Scholar
• Querec, T. et al. Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity. J. Exp. Med. 203, 413–424 (2006)
  PubMed PubMed Central Google Scholar
• Albert, M. L., Sauter, B. & Bhardwaj, N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature 392, 86–89 (1998)
  ADS CAS PubMed Google Scholar
• Khader, S. A. et al. Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J. Exp. Med. 203, 1805–1815 (2006)
  CAS PubMed PubMed Central Google Scholar
• Geijtenbeek, T. B. H. et al. DC-SIGN, a dendritic cell specific HIV-1 binding protein that enhances _trans_-infection of T cells. Cell 100, 587–597 (2000)
  CAS PubMed Google Scholar
• Colonna, M., Krug, A. & Cella, M. Interferon-producing cells: on the front line in immune responses against pathogens. Curr. Opin. Immunol. 14, 373–379 (2002)
  CAS PubMed Google Scholar
• Boscardin, S. B. et al. Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses. J. Exp. Med. 203, 599–606 (2006)
  CAS PubMed PubMed Central Google Scholar
• Soares, H. et al. A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12-independent but CD70-dependent mechanism in vivo.. J. Exp. Med. 204, 1095–1106 (2007)
  CAS PubMed PubMed Central Google Scholar
• Bozzacco, L. et al. DEC-205 receptor on dendritic cells mediates presentation of HIV gag protein to CD8+ T cells in a spectrum of human MHC I haplotypes. Proc. Natl Acad. Sci. USA 104, 1289–1294 (2007)
  ADS CAS PubMed PubMed Central Google Scholar
• Delneste, Y. et al. Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity 17, 353–362 (2002)
  CAS PubMed Google Scholar
• Gabrilovich, D. Mechanisms and functional significance of tumour-induced dendritic-cell defects. Nature Rev. Immunol. 4, 941–952 (2004)
  CAS Google Scholar
• Kortylewski, M. et al. Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity. Nature Med. 11, 1314–1321 (2005)
  CAS PubMed Google Scholar
• Ghiringhelli, F. et al. Tumor cells convert immature myeloid dendritic cells into TGF-β-secreting cells inducing CD4+CD25+ regulatory T cell proliferation. J. Exp. Med. 202, 919–929 (2005)
  CAS PubMed PubMed Central Google Scholar
• Aspord, C. et al. Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development. J. Exp. Med. 204, 1037–1047 (2007)
  CAS PubMed PubMed Central Google Scholar
• Vicari, A. P., Caux, C. & Trinchieri, G. Tumour escape from immune surveillance through dendritic cell inactivation. Semin. Cancer Biol. 12, 33–42 (2002)
  CAS PubMed Google Scholar
• Dhodapkar, K. M., Krasovsky, J., Williamson, B. & Dhodapkar, M. V. Anti-tumor monoclonal antibodies enhance cross-presentation of cellular antigens and the generation of myeloma-specific killer T cells by dendritic cells. J. Exp. Med. 195, 125–133 (2002)
  CAS PubMed PubMed Central Google Scholar
• Kalergis, A. M. & Ravetch, J. V. Inducing tumor immunity through the selective engagement of activating Fcγ receptors on dendritic cells. J. Exp. Med. 195, 1653–1659 (2002)
  CAS PubMed PubMed Central Google Scholar
• Blattman, J. N. & Greenberg, P. D. Cancer immunotherapy: a treatment for the masses. Science 305, 200–205 (2004)
  ADS CAS PubMed Google Scholar
• Shankaran, V. et al. IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410, 1107–1111 (2001)
  ADS CAS PubMed Google Scholar
• Figdor, C. G., De Vries, I. J., Lesterhuis, W. J. & Melief, C. J. Dendritic cell immunotherapy: mapping the way. Nature Med. 10, 475–480 (2004)
  CAS PubMed Google Scholar
• Banchereau, J. & Palucka, A. K. Dendritic cells as therapeutic vaccines against cancer. Nature Rev. Immunol. 5, 296–306 (2005)
  CAS Google Scholar
• Schuler-Thurner, B. et al. Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells. J. Exp. Med. 195, 1279–1288 (2002)
  CAS PubMed PubMed Central Google Scholar
• Paczesny, S. et al. Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells. J. Exp. Med. 199, 1503–1511 (2004)
  CAS PubMed PubMed Central Google Scholar
• Fernandez, N. C. et al. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nature Med. 5, 405–411 (1999)
  CAS PubMed Google Scholar
• Lucas, M., Schachterle, W., Oberle, K., Aichele, P. & Diefenbach, A. Dendritic cells prime natural killer cells by _trans_-presenting interleukin 15. Immunity 26, 503–517 (2007)
  CAS PubMed PubMed Central Google Scholar
• Stary, G. et al. Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells. J. Exp. Med. 204, 1441–1451 (2007)
  CAS PubMed PubMed Central Google Scholar
• Palucka, A. K. et al. Dendritic cells loaded with killed allogeneic melanoma cells can induce objective clinical responses and MART-1 specific CD8+ T-cell immunity. J. Immunother. 29, 545–557 (2006)
  CAS PubMed Google Scholar
• O'Rourke, M. G. et al. Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine. Cancer Immunol. Immunother. 52, 387–395 (2003)
  PubMed Google Scholar
• De Vries, I. J. et al. Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state. Cancer Res. 63, 12–17 (2003)
  CAS PubMed Google Scholar
• Banchereau, J. et al. Immune and clinical responses in patients with metastatic melanoma to CD34+ progenitor-derived dendritic cell vaccine. Cancer Res. 61, 6451–6458 (2001)
  CAS PubMed Google Scholar
• Obeid, M. et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nature Med. 13, 54–61 (2007)
  CAS PubMed Google Scholar
• Gilboa, E. & Vieweg, J. Cancer immunotherapy with mRNA-transfected dendritic cells. Immunol. Rev. 199, 251–263 (2004)
  CAS PubMed Google Scholar
• Soiffer, R. et al. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc. Natl Acad. Sci. USA 95, 13141–13146 (1998)
  ADS CAS PubMed PubMed Central Google Scholar
• Laheru, D. & Jaffee, E. M. Immunotherapy for pancreatic cancer—science driving clinical progress. Nature Rev. Cancer 5, 459–467 (2005)
  CAS Google Scholar
• Fujii, S., Liu, K., Smith, C., Bonito, A. J. & Steinman, R. M. The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J. Exp. Med. 199, 1607–1618 (2004)
  CAS PubMed PubMed Central Google Scholar
• Banchereau, J. & Pascual, V. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity 25, 383–392 (2006)
  CAS PubMed Google Scholar
• Lowes, M. A. et al. Increase in TNFα and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a). Proc. Natl Acad. Sci. USA 102, 19057–19062 (2005)
  ADS CAS PubMed PubMed Central Google Scholar
• Bennett, L. et al. Interferon and granulopoiesis signatures in systemic lupus erythematosus blood. J. Exp. Med. 197, 711–723 (2003)
  CAS PubMed PubMed Central Google Scholar
• Siegal, F. P. et al. The nature of the principal type 1 interferon-producing cells in human blood. Science 284, 1835–1837 (1999)
  CAS PubMed Google Scholar
• Asselin-Paturel, C. & Trinchieri, G. Production of type I interferons: plasmacytoid dendritic cells and beyond. J. Exp. Med. 202, 461–465 (2005)
  CAS PubMed PubMed Central Google Scholar
• Tian, J. et al. Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE. Nature Immunol. 8, 487–496 (2007)
  CAS Google Scholar
• Blanco, P., Palucka, A. K., Gill, M., Pascual, V. & Banchereau, J. Induction of dendritic cell differentiation by IFN-α in systemic lupus erythematosus. Science 294, 1540–1543 (2001)
  ADS CAS PubMed Google Scholar
• Nestle, F. O. et al. Plasmacytoid predendritic cells initiate psoriasis through interferon-α production. J. Exp. Med. 202, 135–143 (2005)
  CAS PubMed PubMed Central Google Scholar
• Hue, S. et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J. Exp. Med. 203, 2473–2483 (2006)
  CAS PubMed PubMed Central Google Scholar
• Tarbell, K. V. et al. Dendritic cell-expanded, islet-specific, CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice. J. Exp. Med. 204, 191–201 (2007)
  CAS PubMed PubMed Central Google Scholar
• Lambrecht, B. N. & Hammad, H. Taking our breath away: dendritic cells in the pathogenesis of asthma. Nature Rev. Immunol. 3, 994–1003 (2003)
  CAS Google Scholar
• Soumelis, V. et al. Human epithelial cells trigger dendritic cell-mediated allergic inflammation by producing TSLP. Nature Immunol. 3, 673–680 (2002)
  CAS Google Scholar
• Traidl-Hoffmann, C. et al. Pollen-associated phytoprostanes inhibit dendritic cell interleukin-12 production and augment T helper type 2 cell polarization. J. Exp. Med. 201, 627–636 (2005)
  CAS PubMed PubMed Central Google Scholar
• Hammad, H. et al. Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J. Exp. Med. 204, 357–367 (2007)
  CAS PubMed PubMed Central Google Scholar
• Inaba, K. et al. Efficient presentation of phagocytosed cellular fragments on the MHC class II products of dendritic cells. J. Exp. Med. 188, 2163–2173 (1998)
  CAS PubMed PubMed Central Google Scholar
• Ochando, J. C. et al. Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nature Immunol. 7, 652–662 (2006)
  CAS Google Scholar
• Hackstein, H. & Thomson, A. W. Dendritic cells: emerging pharmacological targets of immunosuppressive drugs. Nature Rev. Immunol. 4, 24–34 (2004)
  CAS Google Scholar
• Shlomchik, W. D. et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science 285, 412–415 (1999)
  CAS PubMed Google Scholar
• Merad, M. et al. Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nature Med. 10, 510–517 (2004)
  CAS PubMed Google Scholar
• Merad, M. et al. Langerhans cells renew in the skin throughout life under steady-state conditions. Nature Immunol. 3, 1135–1141 (2002)
  CAS Google Scholar
• Rescigno, M. et al. Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nature Immunol. 2, 361–367 (2001)
  CAS Google Scholar
• Coombes, J. L. et al. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β- and retinoic acid-dependent mechanism. J. Exp. Med. 204, 1757–1764 (2007)
  CAS PubMed PubMed Central Google Scholar
• Bousso, P. & Robey, E. Dynamics of CD8+ T cell priming by dendritic cells in intact lymph nodes. Nature Immunol. 4, 579–585 (2003)
  CAS Google Scholar
• Shakhar, G. et al. Stable T cell–dendritic cell interactions precede the development of both tolerance and immunity in vivo. Nature Immunol. 6, 707–714 (2005)
  CAS Google Scholar
• Jung, S. et al. In vivo depletion of CD11c+ dendritic cells abrogation priming of CD8+ T cells by exogenous cell-associated antigens. Immunity 17, 211–220 (2002)
  CAS PubMed PubMed Central Google Scholar
• Heath, W. R. et al. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol. Rev. 199, 9–26 (2004)
  CAS PubMed Google Scholar
• Pulendran, B. Variegation of the immune response with dendritic cells and pathogen recognition receptors. J. Immunol. 174, 2457–2465 (2005)
  CAS PubMed Google Scholar
• Stranges, P. B. et al. Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity. Immunity 26, 629–641 (2007)
  CAS PubMed PubMed Central Google Scholar
• Ohteki, T. et al. Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo. J. Exp. Med. 203, 2329–2338 (2006)
  CAS PubMed PubMed Central Google Scholar
• Granucci, F. et al. Inducible IL-2 production by dendritic cells revealed by global gene expression analysis. Nature Immunol. 2, 882–888 (2001)
  CAS Google Scholar
• Reis e Sousa, C. et al. In vivo microbial stimulation induces rapid CD40L- independent production of IL-12 by dendritic cells and their re-distribution to T cell areas. J. Exp. Med. 186, 1819–1829 (1997)
  CAS PubMed Google Scholar
• Sporri, R. & Reis e Sousa, C. Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nature Immunol. 6, 163–170 (2005)
  Google Scholar
• Sallusto, F. et al. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur. J. Immunol. 28, 2760–2769 (1998)
  CAS PubMed Google Scholar
• Piqueras, B., Connolly, J., Freitas, H., Palucka, A. K. & Banchereau, J. Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors. Blood 107, 2613–2618 (2006)
  CAS PubMed PubMed Central Google Scholar
• Ito, T. et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J. Exp. Med. 202, 1213–1223 (2005)
  CAS PubMed PubMed Central Google Scholar
• Kissenpfennig, A. et al. Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells. Immunity 22, 643–654 (2005)
  CAS PubMed Google Scholar
• Del Rio, M. L., Rodriguez-Barbosa, J. I., Kremmer, E. & Forster, R. CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T Cells. J. Immunol. 178, 6861–6866 (2007)
  CAS PubMed Google Scholar
• Yoneyama, H. et al. Plasmacytoid DCs help lymph node DCs to induce anti-HSV CTLs. J. Exp. Med. 202, 425–435 (2005)
  CAS PubMed PubMed Central Google Scholar
• D'Amico, A. & Wu, L. The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3. J. Exp. Med. 198, 293–303 (2003)
  CAS PubMed PubMed Central Google Scholar
• Karsunky, H., Merad, M., Cozzio, A., Weissman, I. L. & Manz, M. G. Flt3 ligand regulates dendritic cell development from Flt3+ lymphoid and myeloid-committed progenitors to Flt3+ dendritic cells in vivo. J. Exp. Med. 198, 305–313 (2003)
  CAS PubMed PubMed Central Google Scholar
• Leon, B., Lopez-Bravo, M. & Ardavin, C. Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania. Immunity 26, 519–531 (2007)
  CAS PubMed Google Scholar
• Liu, K. et al. Origin of dendritic cells in peripheral lymphoid organs of mice. Nature Immunol. 8, 578–583 (2007)
  CAS Google Scholar
• Varol, C. et al. Monocytes give rise to mucosal, but not splenic, conventional dendritic cells. J. Exp. Med. 204, 171–180 (2007)
  CAS PubMed PubMed Central Google Scholar