Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin (original) (raw)

References

  1. Burke, B. & Ellenberg, J. Remodelling the walls of the nucleus. Nature Rev. Mol. Cell Biol. 3, 487–497 (2002)
    Article CAS Google Scholar
  2. Hetzer, M. W., Walther, T. C. & Mattaj, I. W. Pushing the envelope: structure, function, and dynamics of the nuclear periphery. Annu. Rev. Cell Dev. Biol. 21, 347–380 (2005)
    Article CAS Google Scholar
  3. Hetzer, M. et al. Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly. Nature Cell Biol. 3, 1086–1091 (2001)
    Article CAS Google Scholar
  4. Ye, Y. Diverse functions with a common regulator: ubiquitin takes command of an AAA ATPase. J. Struct. Biol. 156, 29–40 (2006)
    Article CAS Google Scholar
  5. Jentsch, S. & Rumpf, S. Cdc48 (p97): a “molecular gearbox” in the ubiquitin pathway? Trends Biochem. Sci. 32, 6–11 (2007)
    Article CAS Google Scholar
  6. Kondo, H. et al. p47 is a cofactor for p97-mediated membrane fusion. Nature 388, 75–78 (1997)
    Article CAS Google Scholar
  7. Burke, B. The nuclear envelope: filling in gaps. Nature Cell Biol. 3, E273–E274 (2001)
    Article ADS CAS Google Scholar
  8. Meusser, B., Hirsch, C., Jarosch, E. & Sommer, T. ERAD: the long road to destruction. Nature Cell Biol. 7, 766–772 (2005)
    Article CAS Google Scholar
  9. Vagnarelli, P. & Earnshaw, W. C. Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma 113, 211–222 (2004)
    Article Google Scholar
  10. Vong, Q. P., Cao, K., Li, H. Y., Iglesias, P. A. & Zheng, Y. Chromosome alignment and segregation regulated by ubiquitination of survivin. Science 310, 1499–1504 (2005)
    Article ADS CAS Google Scholar
  11. Hagstrom, K. A., Holmes, V. F., Cozzarelli, N. R. & Meyer, B. J. C. elegans condensin promotes mitotic chromosome architecture, centromere organization, and sister chromatid segregation during mitosis and meiosis. Genes Dev. 16, 729–742 (2002)
    Article CAS Google Scholar
  12. Kaitna, S., Pasierbek, P., Jantsch, M., Loidl, J. & Glotzer, M. The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis. Curr. Biol. 12, 798–812 (2002)
    Article CAS Google Scholar
  13. Lipp, J. J., Hirota, T., Poser, I. & Peters, J. M. Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes. J. Cell Sci. 120, 1245–1255 (2007)
    Article CAS Google Scholar
  14. Takemoto, A. et al. Analysis of the role of Aurora B on the chromosomal targeting of condensin I. Nucleic Acids Res. 35, 2403–2412 (2007)
    Article CAS Google Scholar
  15. Hsu, J. Y. et al. Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102, 279–291 (2000)
    Article CAS Google Scholar
  16. Fischle, W. et al. Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature 438, 1116–1122 (2005)
    Article ADS CAS Google Scholar
  17. Hirota, T., Lipp, J. J., Toh, B. H. & Peters, J. M. Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin. Nature 438, 1176–1180 (2005)
    Article ADS CAS Google Scholar
  18. Kourmouli, N. et al. Dynamic associations of heterochromatin protein 1 with the nuclear envelope. EMBO J. 19, 6558–6568 (2000)
    Article CAS Google Scholar
  19. Sessa, F. et al. Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Mol. Cell 18, 379–391 (2005)
    Article CAS Google Scholar
  20. Hauf, S. et al. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J. Cell Biol. 161, 281–294 (2003)
    Article CAS Google Scholar
  21. Sugiyama, K. et al. Aurora-B associated protein phosphatases as negative regulators of kinase activation. Oncogene 21, 3103–3111 (2002)
    Article CAS Google Scholar
  22. Ye, Y., Meyer, H. H. & Rapoport, T. A. Function of the p97–Ufd1–Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J. Cell Biol. 162, 71–84 (2003)
    Article CAS Google Scholar
  23. Kelly, A. E. et al. Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev. Cell 12, 31–43 (2007)
    Article ADS CAS Google Scholar
  24. Poteryaev, D., Squirrell, J. M., Campbell, J. M., White, J. G. & Spang, A. Involvement of the actin cytoskeleton and homotypic membrane fusion in ER dynamics in Caenorhabditis elegans. Mol. Biol. Cell 16, 2139–2153 (2005)
    Article CAS Google Scholar
  25. Mouysset, J., Kahler, C. & Hoppe, T. A conserved role of Caenorhabditis elegans CDC-48 in ER-associated protein degradation. J. Struct. Biol. 156, 41–49 (2006)
    Article CAS Google Scholar
  26. Severson, A. F., Hamill, D. R., Carter, J. C., Schumacher, J. & Bowerman, B. The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis. Curr. Biol. 10, 1162–1171 (2000)
    Article CAS Google Scholar
  27. Kamath, R. S. et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421, 231–237 (2003)
    Article ADS CAS Google Scholar
  28. Meyer, H. H., Shorter, J. G., Seemann, J., Pappin, D. & Warren, G. A complex of mammalian Ufd1 and Npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways. EMBO J. 19, 2181–2192 (2000)
    Article CAS Google Scholar
  29. Murray, A. W. Cell cycle extracts. Methods Cell Biol. 36, 581–605 (1991)
    Article CAS Google Scholar
  30. Lohka, M. J. Analysis of nuclear envelope assembly using extracts of Xenopus eggs. Methods Cell Biol. 53, 367–395 (1998)
    Article CAS Google Scholar
  31. Wang, Y., Satoh, A., Warren, G. & Meyer, H. H. VCIP135 acts as a deubiquitinating enzyme during p97-p47-mediated reassembly of mitotic Golgi fragments. J. Cell Biol. 164, 973–978 (2004)
    Article CAS Google Scholar
  32. Audhya, A. et al. A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. J. Cell Biol. 171, 267–279 (2005)
    Article CAS Google Scholar
  33. Yamauchi, S., Yamanaka, K. & Ogura, T. Comparative analysis of expression of two p97 homologues in Caenorhabditis elegans. Biochem. Biophys. Res. Commun. 345, 746–753 (2006)
    Article CAS Google Scholar

Download references