Latz, E. The inflammasomes: mechanisms of activation and function. Curr. Opin. Immunol.22, 28–33 (2010) ArticleCAS Google Scholar
Kastner, D. L., Aksentijevich, I. & Goldbach-Mansky, R. Autoinflammatory disease reloaded: a clinical perspective. Cell140, 784–790 (2010) ArticleCAS Google Scholar
Franchi, L., Munoz-Planillo, R., Reimer, T., Eigenbrod, T. & Nunez, G. Inflammasomes as microbial sensors. Eur. J. Immunol.40, 611–615 (2010) ArticleCAS Google Scholar
Dostert, C. et al. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science320, 674–677 (2008) ArticleADSCAS Google Scholar
Brookes, P. S., Yoon, Y., Robotham, J. L., Anders, M. W. & Sheu, S.-S. Calcium, ATP, and ROS: a mitochondrial love-hate triangle. Am. J. Physiol. Cell Physiol.287, C817–C833 (2004) ArticleCAS Google Scholar
Li, N. et al. Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production. J. Biol. Chem.278, 8516–8525 (2003) ArticleCAS Google Scholar
Goldman, S. J., Taylor, R., Zhang, Y. & Jin, S. Autophagy and the degradation of mitochondria. Mitochondrion10, 309–315 (2010) ArticleCAS Google Scholar
Levine, B. & Kroemer, G. Autophagy in the pathogenesis of disease. Cell132, 27–42 (2008) ArticleCAS Google Scholar
Veal, E. A., Day, A. M. & Morgan, B. A. Hydrogen peroxide sensing and signaling. Mol. Cell26, 1–14 (2007) ArticleCAS Google Scholar
Moore, C. B. et al. NLRX1 is a regulator of mitochondrial antiviral immunity. Nature451, 573–577 (2008) ArticleADSCAS Google Scholar
Tattoli, I. et al. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-κB and JNK pathways by inducing reactive oxygen species production. EMBO Rep.9, 293–300 (2008) ArticleCAS Google Scholar
Hayashi, T., Rizzuto, R., Hajnoczky, G. & Su, T. P. MAM: more than just a housekeeper. Trends Cell Biol.19, 81–88 (2009) ArticleCAS Google Scholar
Zhou, R., Tardivel, A., Thorens, B., Choi, I. & Tschopp, J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nature Immunol.11, 136–140 (2010) ArticleCAS Google Scholar
Saxena, G., Chen, J. & Shalev, A. Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein. J. Biol. Chem.285, 3997–4005 (2010) ArticleCAS Google Scholar
Colombini, M. VDAC: the channel at the interface between mitochondria and the cytosol. Mol. Cell. Biochem.256, 107–115 (2004) Article Google Scholar
Oliveira, J. M. Nature and cause of mitochondrial dysfunction in Huntington’s disease: focusing on Huntingtin and the striatum. J. Neurochem.114, 1–12 (2010) CASPubMed Google Scholar
Restivo, N. L., Srivastava, M. D., Schafer, I. A. & Hoppel, C. L. Mitochondrial dysfunction in a patient with crohn disease: possible role in pathogenesis. J. Pediatr. Gastroenterol. Nutr.38, 534–538 (2004) Article Google Scholar
Saitoh, T. et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production. Nature456, 264–268 (2008) ArticleADSCAS Google Scholar
Yamagata, H. et al. Requirement of voltage-dependent anion channel 2 for pro-apoptotic activity of Bax. Oncogene28, 3563–3572 (2009) ArticleCAS Google Scholar
Sato, T. et al. Fas-mediated apoptosome formation is dependent on reactive oxygen species derived from mitochondrial permeability transition in Jurkat cells. J. Immunol.173, 285–296 (2004) ArticleCAS Google Scholar
Mariathasan, S. et al. Differential activation of the inflammasome by caspase-1adaptors ASC and Ipaf. Nature430, 213–218 (2004) ArticleADSCAS Google Scholar
Martinon, F., Petrilli, V., Mayor, A., Tardivel, A. & Tschopp, J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature440, 237–241 (2006) ArticleADSCAS Google Scholar
Domen, J., Cheshier, S. H. & Weissman, I. L. The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential. J. Exp. Med.191, 253–264 (2000) ArticleCAS Google Scholar
Wieckowski, M. R., Giorgi, C., Lebiedzinska, M., Duszynski, J. & Pinton, P. Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells. Nature Protocols4, 1582–1590 (2009) ArticleCAS Google Scholar
Didierlaurent, A. et al. Tollip regulates proinflammatory responses to interleukin-1 and lipopolysaccharide. Mol. Cell. Biol.26, 735–742 (2006) ArticleCAS Google Scholar
Papin, S. et al. The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing. Cell Death Differ.14, 1457–1466 (2007) ArticleCAS Google Scholar