Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture (original) (raw)

References

  1. Keller, G.M. In vitro differentiation of embryonic stem cells. Curr. Opin. Cell. Biol. 7, 862–869 (1995).
    Article CAS Google Scholar
  2. Smith, A.G. Embryo-derived stem cells: of mice and men. Ann. Rev. Cell Dev. Biol. 17, 435–462 (2001).
    Article CAS Google Scholar
  3. Bain, G., Kitchens, D., Yao, M., Huettner, J.E. & Gottlieb, D.I. Embryonic stem cells express neuronal properties in vitro. Dev. Biol. 168, 342–357 (1995).
    Article CAS Google Scholar
  4. Wiles, M.V. & Johansson, B.M. Embryonic stem cell development in a chemically defined medium. Exp. Cell Res. 247, 241–248 (1999).
    Article CAS Google Scholar
  5. Kawasaki, H. et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28, 31–40 (2000).
    Article CAS Google Scholar
  6. Munoz-Sanjuan, I. & Brivanlou, A.H. Neural induction, the default model and embryonic stem cells. Nat. Rev. Neurosci. 3, 271–280 (2002).
    Article CAS Google Scholar
  7. Wilson, S.I. & Edlund, T. Neural induction: toward a unifying mechanism. Nat. Neurosci. 4 (Suppl.), 1161–1168 (2001).
    Article CAS Google Scholar
  8. Tropepe, V. et al. Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 30, 65–78 (2001).
    Article CAS Google Scholar
  9. Wood, H.B. & Episkopou, V. Comparative expression of the mouse Sox1, Sox2 and Sox3 genes from pre-gastrulation to early somite stages. Mech. Dev. 86, 197–201 (1999).
    Article CAS Google Scholar
  10. Aubert, J., Dunstan, H., Chambers, I. & Smith, A. Functional gene screening in embryonic stem cells implicates Wnt antagonism in neural differentiation. Nat. Biotechnol. 20, 1240–1245 (2002).
    Article CAS Google Scholar
  11. Tucker, K.L., Meyer, M. & Barde, Y.A. Neurotrophins are required for nerve growth during development. Nat. Neurosci. 4, 29–37 (2001).
    Article CAS Google Scholar
  12. Lee, S.H., Lumelsky, N., Studer, L., Auerbach, J.M. & McKay, R.D. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat. Biotechnol. 18, 675–679 (2000).
    Article CAS Google Scholar
  13. Niwa, H., Miyazaki, J. & Smith, A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat. Genet. 24, 372–376 (2000).
    Article CAS Google Scholar
  14. Ying, Q.L., Nichols, J., Evans, E.P. & Smith, A.G. Changing potency by spontaneous fusion. Nature 416, 545–548 (2002).
    Article CAS Google Scholar
  15. Cebria, F. et al. FGFR-related gene nou-darake restricts brain tissues to the head region of planarians. Nature 419, 620–624 (2002).
    Article CAS Google Scholar
  16. Launay, C., Fromentoux, V., Shi, D.L. & Boucaut, J.C. A truncated FGF receptor blocks neural induction by endogenous Xenopus inducers. Development 122, 869–880 (1996).
    CAS Google Scholar
  17. Streit, A., Berliner, A.J., Papanayotou, C., Sirulnik, A. & Stern, C.D. Initiation of neural induction by FGF signalling before gastrulation. Nature 406, 74–78 (2000).
    Article CAS Google Scholar
  18. Wilson, S.I., Graziano, E., Harland, R., Jessell, T.M. & Edlund, T. An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo. Curr. Biol. 10, 421–429 (2000).
    Article CAS Google Scholar
  19. Mohammadi, M. et al. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 276, 955–960 (1997).
    Article CAS Google Scholar
  20. Li, X. et al. Fibroblast growth factor signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid body. J. Cell Biol. 153, 811–822 (2001).
    Article CAS Google Scholar
  21. Feldman, B., Poueymirou, W., Papaioannou, V.E., DeChiara, T.M. & Goldfarb, M. Requirement of FGF-4 for postimplantation mouse development. Science 267, 246–249 (1995).
    Article CAS Google Scholar
  22. Arman, E., Krausz-Haffner, R., Chen, Y., Heath, J.K. & Lonai, P. Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc. Natl. Acad. Sci. USA 95, 5082–5087 (1998).
    Article CAS Google Scholar
  23. Nichols, J., Chambers, I., Taga, T. & Smith, A.G. Physiological rationale for responsiveness of mouse epiblast and embryonic stem cells to gp130 cytokines. Development 128, 2333–2339 (2001).
    CAS PubMed Google Scholar

Download references