The Arp2/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors (original) (raw)
Bray, S. J. Notch signalling: a simple pathway becomes complex. Nature Rev. Mol. Cell Biol.7, 678–689 (2006). CAS Google Scholar
Schweisguth, F. Regulation of Notch signaling activity. Curr. Biol.14, R129–138 (2004). CASPubMed Google Scholar
Louvi, A. & Artavanis-Tsakonas, S. Notch signalling in vertebrate neural development. Nature Rev.7, 93–102 (2006). CAS Google Scholar
Bray S. Notch signalling in Drosophila: three ways to use a pathway. Sem. Cell Dev. Biol.9, 591–597 (1998). CAS Google Scholar
Le Borgne, R. & Schweisguth, F. Unequal segregation of Neuralized biases Notch activation during asymmetric cell division. Dev. Cell5, 139–148 (2003). CASPubMed Google Scholar
Rhyu, M. S., Jan, L. Y. & Jan, Y. N. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell76, 477–491 (1994). CASPubMed Google Scholar
Gho, M., Bellaiche, Y. & Schweisguth, F. Revisiting the Drosophila microchaete lineage: a novel intrinsically asymmetric cell division generates a glial cell. Development126, 3573–3584 (1999). CASPubMed Google Scholar
Zeng, C., Younger-Shepherd, S., Jan, L. Y. & Jan, Y. N. Delta and Serrate are redundant Notch ligands required for asymmetric cell divisions within the Drosophila sensory organ lineage. Genes Dev.12, 1086–1091 (1998). CASPubMedPubMed Central Google Scholar
Parks, A. L., Klueg, K. M., Stout, J. R. & Muskavitch, M. A. Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development127, 1373–1385 (2000). CASPubMed Google Scholar
Wang, W. & Struhl, G. Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch. Development131, 5367–5380 (2004). CASPubMed Google Scholar
Emery, G. et al. Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell122, 763–773 (2005). CASPubMed Google Scholar
Jafar-Nejad, H. et al. Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors. Dev. Cell9, 351–363 (2005). CASPubMed Google Scholar
Hartenstein, V. & Posakony, J. W. A dual function of the Notch gene in Drosophila sensillum development. Dev. Biol.142, 13–30 (1990). CASPubMed Google Scholar
Berdnik, D., Torok, T., Gonzalez-Gaitan, M. & Knoblich, J. A. The endocytic protein α-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev. Cell3, 221–231 (2002). CASPubMed Google Scholar
Tien, A. C. et al. Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster. J. Cell Biol.182, 1113–1125 (2008). CASPubMedPubMed Central Google Scholar
Zhai, R. G. et al. Mapping Drosophila mutations with molecularly defined P element insertions. Proc. Natl Acad. Sci. USA100, 10860–10865 (2003). CASPubMedPubMed Central Google Scholar
Hudson, A. M. & Cooley, L. A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex. J. Cell Biol.156, 677–687 (2002). CASPubMedPubMed Central Google Scholar
Machesky, L. M. & Gould, K. L. The Arp2/3 complex: a multifunctional actin organizer. Curr. Opin. Cell Biol.11, 117–121 (1999). CASPubMed Google Scholar
Tal, T., Vaizel-Ohayon, D. & Schejter, E. D. Conserved interactions with cytoskeletal but not signaling elements are an essential aspect of Drosophila WASp function. Dev. Biol.243, 260–271 (2002). CASPubMed Google Scholar
Machesky, L. M. & Insall, R. H. Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex. Curr. Biol.8, 1347–1356 (1998). CASPubMed Google Scholar
Ben-Yaacov, S., Le Borgne, R., Abramson, I., Schweisguth, F. & Schejter, E. D. Wasp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling. J. Cell Biol.152, 1–13 (2001). CASPubMedPubMed Central Google Scholar
Struhl, G., Fitzgerald, K. & Greenwald, I. Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell74, 331–345 (1993). CASPubMed Google Scholar
Ruohola, H. et al. Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila. Cell66, 433–449 (1991). CASPubMed Google Scholar
Lopez-Schier, H. & St Johnston, D. Delta signaling from the germ line controls the proliferation and differentiation of the somatic follicle cells during Drosophila oogenesis. Genes Dev.15, 1393–1405 (2001). CASPubMed Google Scholar
Assa-Kunik, E., Torres, I. L., Schejter, E. D., Johnston, D. S. & Shilo, B. Z. Drosophila follicle cells are patterned by multiple levels of Notch signaling and antagonism between the Notch and JAK/STAT pathways. Development134, 1161–1169 (2007). CASPubMed Google Scholar
Sun, J. & Deng, W. M. Hindsight mediates the role of notch in suppressing hedgehog signaling and cell proliferation. Dev. Cell12, 431–442 (2007). CASPubMedPubMed Central Google Scholar
de Celis, J. F., Garcia-Bellido, A. & Bray, S. J. Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development122, 359–369 (1996). CASPubMed Google Scholar
de Celis, J. F. & Bray, S. Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing. Development124, 3241–3251 (1997). CASPubMed Google Scholar
Micchelli, C. A., Rulifson, E. J. & Blair, S. S. The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate. Development124, 1485–1495 (1997). CASPubMed Google Scholar
Seugnet, L., Simpson, P. & Haenlin, M. Requirement for dynamin during Notch signaling in Drosophila neurogenesis. Dev. Biol.192, 585–598 (1997). CASPubMed Google Scholar
Kaksonen, M., Toret, C. P. & Drubin, D. G. A modular design for the clathrin- and actin-mediated endocytosis machinery. Cell123, 305–320 (2005). CASPubMed Google Scholar
Galletta, B. J., Chuang, D. Y. & Cooper, J. A. Distinct roles for Arp2/3 regulators in actin assembly and endocytosis. PLoS Biol.6, e1 (2008). PubMedPubMed Central Google Scholar
Chen, M. S. et al. Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis. Nature351, 583–586 (1991). CASPubMed Google Scholar
van der Bliek, A. M. & Meyerowitz, E. M. Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic. Nature351, 411–414 (1991). CASPubMed Google Scholar
Le Borgne, R., Bellaiche, Y. & Schweisguth, F. Drosophila E-cadherin regulates the orientation of asymmetric cell division in the sensory organ lineage. Curr. Biol.12, 95–104 (2002). CASPubMed Google Scholar
Lai, E. C. & Rubin, G. M. neuralized functions cell-autonomously to regulate a subset of notch-dependent processes during adult Drosophila development. Dev. Biol.231, 217–233 (2001). CASPubMed Google Scholar
Maupin, P. & Pollard, T. D. Improved preservation and staining of HeLa cell actin filaments, clathrin-coated membranes, and other cytoplasmic structures by tannic acid-glutaraldehyde-saponin fixation. J. Cell Biol.96, 51–62 (1983). CASPubMed Google Scholar
Heintzelman, M. B. & Mooseker, M. S. Assembly of the intestinal brush border cytoskeleton. Curr. Top. Dev. Biol.26, 93–122 (1992). CASPubMed Google Scholar
Majstoravich, S. et al. Lymphocyte microvilli are dynamic, actin-dependent structures that do not require Wiskott-Aldrich syndrome protein (WASp) for their morphology. Blood104, 1396–1403 (2004). CASPubMed Google Scholar
von Andrian, U. H., Hasslen, S. R., Nelson, R. D., Erlandsen, S. L. & Butcher, E. C. A central role for microvillous receptor presentation in leukocyte adhesion under flow. Cell82, 989–999 (1995). CASPubMed Google Scholar
Singer, II. et al. CCR5, CXCR4, and CD4 are clustered and closely apposed on microvilli of human macrophages and T cells. J. Virol.75, 3779–3790 (2001). CASPubMedPubMed Central Google Scholar
Morgan, N. S., Heintzelman, M. B. & Mooseker, M. S. Characterization of myosin-IA and myosin-IB, two unconventional myosins associated with the Drosophila brush border cytoskeleton. Dev. Biol.172, 51–71 (1995). CASPubMed Google Scholar
Le Borgne, R. Regulation of Notch signalling by endocytosis and endosomal sorting. Curr. Opin. Cell Biol.18, 213–222 (2006). CASPubMed Google Scholar
Emery, G. & Knoblich, J. A. Endosome dynamics during development. Curr. Opin. Cell Biol.18, 407–415 (2006). CASPubMed Google Scholar
Chhabra, E. S. & Higgs, H. N. The many faces of actin: matching assembly factors with cellular structures. Nature Cell Biol.9, 1110–1121 (2007). CASPubMed Google Scholar
De Joussineau, C. et al. Delta-promoted filopodia mediate long-range lateral inhibition in Drosophila. Nature426, 555–559 (2003). CASPubMed Google Scholar
Mullins, R. D., Heuser, J. A. & Pollard, T. D. The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Proc. Natl Acad. Sci. USA95, 6181–6186 (1998). CASPubMedPubMed Central Google Scholar
Rohatgi, R., Milenkovic, L. & Scott, M. P. Patched1 regulates hedgehog signaling at the primary cilium. Science317, 372–376 (2007). CASPubMed Google Scholar
Kiprilov, E. N. et al. Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery. J. Cell Biol.180, 897–904 (2008). CASPubMedPubMed Central Google Scholar
Ilagan, M. X. & Kopan, R. SnapShot: notch signaling pathway. Cell128, 1246 (2007). PubMed Google Scholar
Chen, H. & De Camilli, P. The association of epsin with ubiquitinated cargo along the endocytic pathway is negatively regulated by its interaction with clathrin. Proc. Natl Acad. Sci. USA102, 2766–2771 (2005). CASPubMedPubMed Central Google Scholar
Sigismund, S. et al. Clathrin-independent endocytosis of ubiquitinated cargos. Proc. Natl Acad. Sci. USA102, 2760–2765 (2005). CASPubMedPubMed Central Google Scholar
Imai, K., Nonoyama, S. & Ochs, H. D. WASP (Wiskott-Aldrich syndrome protein) gene mutations and phenotype. Curr. Opin. Allergy Clin. Immunol.3, 427–436 (2003). CASPubMed Google Scholar
Tanigaki, K. & Honjo, T. Regulation of lymphocyte development by Notch signaling. Nature Immunol.8, 451–456 (2007). CAS Google Scholar
Osborne, B. A. & Minter, L. M. Notch signalling during peripheral T-cell activation and differentiation. Nature Rev. Immunol.7, 64–75 (2007). CAS Google Scholar
Struhl, G. & Greenwald, I. Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila. Proc. Natl Acad. Sci.USA98, 229–234 (2001). CASPubMed Google Scholar
Hudson, A. M. & Cooley, L. A subset of dynamic actin rearrangements in Drosophila requires the Arp2/3 complex. J. Cell Biol.156, 677–687 (2002). CASPubMedPubMed Central Google Scholar
Ben-Yaacov, S., Le Borgne, R., Abramson, I., Schweisguth, F. & Schejter, E. D. Wasp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling. J. Cell Biol.152, 1–13 (2001). CASPubMedPubMed Central Google Scholar
Zallen, J. A. et al. SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila. J. Cell Biol.156, 689–701 (2002). CASPubMedPubMed Central Google Scholar
Watts, R. J., Schuldiner, O., Perrino, J., Larsen, C. & Luo, L. Glia engulf degenerating axons during developmental axon pruning. Curr. Biol.14, 678–684 (2004). CASPubMed Google Scholar
Lai, E. C. & Rubin, G. M. neuralized functions cell-autonomously to regulate a subset of notch-dependent processes during adult Drosophila development. Dev. Biol.231, 217–233 (2001). CASPubMed Google Scholar
Frise, E., Knoblich, J. A., Younger-Shepherd, S., Jan, L. Y. & Jan, Y. N. The Drosophila Numb protein inhibits signaling of the Notch receptor during cell–cell interaction in sensory organ lineage. Proc. Natl Acad. Sci. USA93, 11925–11932 (1996). CASPubMedPubMed Central Google Scholar
Berdnik, D., Torok, T., Gonzalez-Gaitan, M. & Knoblich, J. A. The endocytic protein α-Adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev. Cell3, 221–231 (2002). CASPubMed Google Scholar
Lai, E. C., Deblandre, G. A., Kintner, C. & Rubin, G. M. Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of Delta. Dev. Cell1, 783–794 (2001). CASPubMed Google Scholar
Manning, L. & Doe, C. Q. Prospero distinguishes sibling cell fate without asymmetric localization in the Drosophila adult external sense organ lineage. Development126, 2063–2071 (1999). CASPubMed Google Scholar
Wang, W. & Struhl, G. Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch. Development131, 5367–5380 (2004). CASPubMed Google Scholar
Tien, A. C. et al. Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster. J. Cell Biol.182, 1113–1125 (2008). CASPubMedPubMed Central Google Scholar
Blochlinger, K., Bodmer, R., Jan, L. Y. & Jan, Y. N. Patterns of expression of cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos. Genes Dev.4, 1322–1331 (1990). CASPubMed Google Scholar
Robinow, S. & White, K. Characterization and spatial distribution of the ELAV protein during Drosophila melanogaster development. J. Neurobiol.22, 443–461 (1991). CASPubMed Google Scholar
Nolo, R., Abbott, L. A. & Bellen, H. J. Senseless, a Zn finger transcription factor, is necessary and sufficient for sensory organ development in Drosophila. Cell102, 349–362 (2000). CASPubMed Google Scholar
Fehon, R. G. et al. Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell61, 523–534 (1990). CASPubMed Google Scholar
Parks, A. L., Klueg, K. M., Stout, J. R. & Muskavitch, M. A. Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development127, 1373–1385 (2000). CASPubMed Google Scholar
Patel, N. H., Snow, P. M. & Goodman, C. S. Characterization and cloning of fasciclin III: a glycoprotein expressed on a subset of neurons and axon pathways in Drosophila. Cell48, 975–988 (1987). CASPubMed Google Scholar
Yip, M. L., Lamka, M. L. & Lipshitz, H. D. Control of germ-band retraction in Drosophila by the zinc-finger protein HINDSIGHT. Development124, 2129–2141 (1997). CASPubMed Google Scholar
Woods, D. F. & Bryant, P. J. The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions. Cell66, 451–464 (1991). CASPubMed Google Scholar
Morgan, N. S., Heintzelman, M. B. & Mooseker, M. S. Characterization of myosin-IA and myosin-IB, two unconventional myosins associated with the Drosophila brush border cytoskeleton. Dev. Biol.172, 51–71 (1995). CASPubMed Google Scholar
Rhyu, M. S., Jan, L. Y. & Jan, Y. N. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell76, 477–491 (1994). CASPubMed Google Scholar
Oda, H., Uemura, T., Harada, Y., Iwai, Y. & Takeichi, M. A Drosophila homolog of cadherin associated with armadillo and essential for embryonic cell–cell adhesion. Dev. Biol.165, 716–726 (1994). CASPubMed Google Scholar
Wucherpfennig, T., Wilsch-Brauninger, M. & Gonzalez-Gaitan, M. Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release. J. Cell Biol.161, 609–624 (2003). CASPubMedPubMed Central Google Scholar
Dollar, G., Struckhoff, E., Michaud, J. & Cohen, R. S. Rab11 polarization of the Drosophila oocyte: a novel link between membrane trafficking, microtubule organization, and oskar mRNA localization and translation. Development129, 517–526 (2002). CASPubMed Google Scholar
Sweeney, S. T. & Davis, G. W. Unrestricted synaptic growth in spinster-a late endosomal protein implicated in TGF-β-mediated synaptic growth regulation. Neuron36, 403–416 (2002). CASPubMed Google Scholar
Lloyd, T. E. et al. Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila. Cell108, 261–269 (2002). CASPubMed Google Scholar
Larsen, C. W., Hirst, E., Alexandre, C. & Vincent, J. P. Segment boundary formation in Drosophila embryos. Development130, 5625–5635 (2003). CASPubMed Google Scholar
Maupin, P. & Pollard, T. D. Improved preservation and staining of HeLa cell actin filaments, clathrin-coated membranes, and other cytoplasmic structures by tannic acid-glutaraldehyde-saponin fixation. J. Cell Biol.96, 51–62 (1983). CASPubMed Google Scholar
Le Borgne, R. & Schweisguth, F. Unequal segregation of Neuralized biases Notch activation during asymmetric cell division. Dev. Cell5, 139–148 (2003). CASPubMed Google Scholar
Emery, G. et al. Asymmetric Rab 11 endosomes regulate Delta recycling and specify cell fate in the Drosophila nervous system. Cell122, 763–773 (2005). CASPubMed Google Scholar