Nf1 has an essential role in endothelial cells (original) (raw)

• Friedman, J.M. et al. Cardiovascular disease in neurofibromatosis 1: report of the NF1 Cardiovascular Task Force. Genet. Med. 4, 105–111 (2002).
  Article CAS PubMed Google Scholar
• Lin, A.E. et al. Cardiovascular malformations and other cardiovascular abnormalities in neurofibromatosis 1. Am. J. Med. Genet. 95, 108–117 (2000).
  Article CAS PubMed Google Scholar
• Jacks, T. et al. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1. Nat. Genet. 7, 353–361 (1994).
  Article CAS PubMed Google Scholar
• Brannan, C.I. et al. Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Dev. 8, 1019–1029 (1994).
  Article CAS PubMed Google Scholar
• Lakkis, M.M. & Epstein, J.A. Neurofibromin modulation of ras activity is required for normal endocardial–mesenchymal transformation in the developing heart. Development 125, 4359–4367 (1998).
  CAS PubMed Google Scholar
• Kirby, M.L., Gale, T.F. & Stewart, D.E. Neural crest cells contribute to normal aorticopulmonary septation. Science 220, 1059–1061 (1983).
  Article CAS PubMed Google Scholar
• Zhu, Y. et al. Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain. Genes Dev. 15, 859–876 (2001).
  Article CAS PubMed PubMed Central Google Scholar
• Kisanuki, Y.Y. et al. Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo. Dev. Biol. 230, 230–242 (2001).
  Article CAS PubMed Google Scholar
• Meyer, D. & Birchmeier, C. Multiple essential functions of neuregulin in development. Nature 378, 386–390 (1995).
  Article CAS PubMed Google Scholar
• Erickson, S.L. et al. ErbB3 is required for normal cerebellar and cardiac development: a comparison with ErbB2- and heregulin-deficient mice. Development 124, 4999–5011 (1997).
  CAS PubMed Google Scholar
• Morrison-Graham, K., Schatteman, G., Bork, T., Bowen-Pope, D. & Weston, J. A PDGF receptor mutation in the mouse (Patch) perturbs the development of a non-neuronal subset of neural crest–derived cells. Development 115, 133–142 (1992).
  CAS PubMed Google Scholar
• Epstein, J. Pax3, neural crest and cardiovascular development. Trends Cardiovasc. Med. 6, 255–261 (1996).
  Article CAS PubMed Google Scholar
• Feiner, L. et al. Targeted disruption of semaphorin 3C leads to persistent truncus arteriosus and aortic arch interruption. Development 128, 3061–3070 (2001).
  CAS PubMed Google Scholar
• Galvin, K.M. et al. A role for smad6 in development and homeostasis of the cardiovascular system. Nat. Genet. 24, 171–174 (2000).
  Article CAS PubMed Google Scholar
• Ya, J. et al. Sox4-deficiency syndrome in mice is an animal model for common trunk. Circ. Res. 83, 986–994 (1998).
  Article CAS PubMed Google Scholar
• Yang, J.T., Rayburn, H. & Hynes, R.O. Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development. Development 121, 549–560 (1995).
  CAS PubMed Google Scholar
• de la Pompa, J.L. et al. Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum. Nature 392, 182–186 (1998).
  Article CAS PubMed Google Scholar
• Camenisch, T.D. et al. Disruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchyme. J. Clin. Invest. 106, 349–360 (2000).
  Article CAS PubMed PubMed Central Google Scholar
• Chen, B. et al. Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis. Nat. Genet. 24, 296–299 (2000).
  Article CAS PubMed Google Scholar
• Ranger, A.M. et al. The transcription factor NF-ATc is essential for cardiac valve formation. Nature 392, 186–190 (1998).
  Article CAS PubMed Google Scholar
• Ichida, M. & Finkel, T. Ras regulates NFAT3 activity in cardiac myocytes. J. Biol. Chem. 276, 3524–3530 (2001).
  Article CAS PubMed Google Scholar
• Woodrow, M.A., Rayter, S., Downward, J. & Cantrell, D.A. p21ras function is important for T-cell antigen receptor and protein kinase C regulation of nuclear factor of activated T cells. J. Immunol. 150, 3853–3861 (1993).
  CAS PubMed Google Scholar
• Vogel, K.S. et al. Mouse tumor model for neurofibromatosis type 1. Science 286, 2176–2179 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Cichowski, K. et al. Mouse models of tumor development in neurofibromatosis type 1. Science 286, 2172–2176 (1999).
  Article CAS PubMed Google Scholar
• Jiang, X., Rowitch, D.H., Soriano, P., McMahon, A.P. & Sucov, H.M. Fate of the mammalian cardiac neural crest. Development 127, 1607–1616 (2000).
  CAS PubMed Google Scholar
• Li, J., Chen, F. & Epstein, J.A. Neural crest expression of Cre recombinase directed by the proximal Pax3 promoter in transgenic mice. Genesis 26, 162–164 (2000).
  Article CAS PubMed Google Scholar
• Yamauchi, Y. et al. A novel transgenic technique that allows specific marking of the neural crest cell lineage in mice. Dev. Biol. 212, 191–203 (1999).
  Article CAS PubMed Google Scholar
• Ricci, A. Jr. et al. Malignant peripheral nerve sheath tumors arising from ganglioneuromas. Am. J. Surg. Pathol. 8, 19–29 (1984).
  Article PubMed Google Scholar
• Novak, A., Guo, C., Yang, W., Nagy, A. & Lobe, C.G. Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis 28, 147–155 (2000).
  Article CAS PubMed Google Scholar
• Soriano, P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21, 70–71 (1999).
  Article CAS PubMed Google Scholar