Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome (original) (raw)

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Acknowledgements

We wish to thank the individuals and their families who participated in this study and the doctors who referred the cases. The support of CFC International in facilitating the collection of patient samples is gratefully acknowledged. We are grateful to J. Miyazaki, Osaka University, for supplying the pCAGGS expression vector. This work was supported by Grants-in-Aid from the Ministry of Education, Culture, Sports, Science and Technology of Japan and Grants-in-Aid from the Ministry of Health, Labor, and Welfare of Japan.

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Authors and Affiliations

1. Department of Medical Genetics, Tohoku University School of Medicine, Sendai, Japan
   Tetsuya Niihori, Yoko Aoki, Yoko Narumi, Kumi Kato, Shigeo Kure & Yoichi Matsubara
2. Università Cattolica, Istituto di Genetica Medica, Rome, Italy
   Giovanni Neri
3. Department of Genetics, Hôpital Robert Debré (APHP), Paris, France
   Hélène Cavé, Alain Verloes & Clarisse Baumann
4. Department of Planning and Research, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Osaka, Japan
   Nobuhiko Okamoto
5. Clinical and Molecular Genetics Unit, Institute of Child Health, London, UK
   Raoul C M Hennekam
6. Department of Pediatrics, Academic Medical Center, Amsterdam, The Netherlands
   Raoul C M Hennekam
7. Institut für Humangenetik, Universität Essen, Essen, Germany
   Gabriele Gillessen-Kaesbach & Dagmar Wieczorek
8. Medical Genetics Center, Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil
   Maria Ines Kavamura
9. Division of Medical Genetics, Kanagawa Children's Medical Center, Yokohama, Japan
   Kenji Kurosawa
10. Division of Medical Genetics, Saitama Children's Medical Center, Saitama, Japan
    Hirofumi Ohashi
11. Great Ormond Street Hospital, London, UK
    Louise Wilson
12. Genetic Department, Pitie-Salpetriere University Hospital, Paris, France
    Delphine Heron
13. Genetic Department, University Hospital, Angers, France
    Dominique Bonneau
14. Dipartimento di Scienze Pediatriche Mediche e Chirurgiche, Unità Operativa Complessa Patologia Neonatale e Terapia Intensiva, Azienda Ospedaliera Universitaria G. Martino, Messina, Italy
    Giuseppina Corona
15. Department of Medical Genetics, University of the Ryukyus School of Medicine, Okinawa, Japan
    Tadashi Kaname & Kenji Naritomi
16. Department of Human Genetics, Yokohama City University Graduate School of Medicine, Yokahama, Japan
    Naomichi Matsumoto
17. Comprehensive Research and Education Center for Planning of Drug Development and Clinical Evaluation, 21st Century COE Program, Tohoku University, Sendai, Japan
    Kumi Kato & Yoichi Matsubara

Authors

1. Tetsuya Niihori
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2. Yoko Aoki
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3. Yoko Narumi
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4. Giovanni Neri
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5. Hélène Cavé
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6. Alain Verloes
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7. Nobuhiko Okamoto
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8. Raoul C M Hennekam
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9. Gabriele Gillessen-Kaesbach
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10. Dagmar Wieczorek
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11. Maria Ines Kavamura
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12. Kenji Kurosawa
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13. Hirofumi Ohashi
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14. Louise Wilson
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15. Delphine Heron
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16. Dominique Bonneau
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17. Giuseppina Corona
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18. Tadashi Kaname
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19. Kenji Naritomi
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20. Clarisse Baumann
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21. Naomichi Matsumoto
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22. Kumi Kato
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23. Shigeo Kure
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24. Yoichi Matsubara
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Corresponding author

Correspondence toYoko Aoki.

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The authors declare no competing financial interests.

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Niihori, T., Aoki, Y., Narumi, Y. et al. Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome.Nat Genet 38, 294–296 (2006). https://doi.org/10.1038/ng1749

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• Received: 20 November 2005
• Accepted: 17 January 2006
• Published: 12 February 2006
• Issue Date: 01 March 2006
• DOI: https://doi.org/10.1038/ng1749