Mutations in LGI1 cause autosomal-dominant partial epilepsy with auditory features (original) (raw)

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Acknowledgements

This work was supported by grants from the National Institutes of Health, National Institute of Neurological Disorders and Stroke and by funds from the Columbia Genome Center. We thank A. Efstratiadis, I. Dragatsis, I. Lipkin, M. Hornig and H. Scharfman for their critical discussions and helpful suggestions; J. Ju, A.K. Tong and C. Wang for timely technical assistance; P. McCabe, C.D. McNew and S.R. Resor for family referrals and W. Jimenez for assistance with database management. This research would not have been possible without the generous participation of the families described.

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Authors and Affiliations

  1. Columbia Genome Center, Columbia University, 630 W 168 Street, P&S Box 16, New York, 10032, New York, USA
    Sergey Kalachikov, Oleg Evgrafov, Barbara Ross, Pavel Morozov, Kamna Das, Elita Teplitskaya, Andrew Yu, Eftihia Cayanis, Graciela Penchaszadeh & T. Conrad Gilliam
  2. G.H. Sergievsky Center, Columbia University, 630 W 168 Street, P&S Box 16, New York, 10032, New York, USA
    Melodie Winawer, Christie Barker-Cummings, Filippo Martinelli Boneschi, W. Allen Hauser & Ruth Ottman
  3. Department of Epidemiology, Columbia University, 630 W 168 Street, P&S Box 16, New York, 10032, New York, USA
    Christie Barker-Cummings, Filippo Martinelli Boneschi, W. Allen Hauser & Ruth Ottman
  4. Department of Psychiatry, Columbia University, 630 W 168 Street, P&S Box 16, New York, 10032, New York, USA
    Graciela Penchaszadeh & T. Conrad Gilliam
  5. Department of Neurology, Columbia University, 630 W 168 Street, P&S Box 16, New York, 10032, New York, USA
    Melodie Winawer, Timothy A. Pedley & W. Allen Hauser
  6. Departments of Genetics and Development, Columbia University, 630 W 168 Street, P&S Box 16, New York, 10032, New York, USA
    T. Conrad Gilliam
  7. Department of Epidemiology of Brain Disorders, New York State Psychiatric Institute, New York, New York, USA
    Ruth Ottman
  8. Department of Medical Genetics, New York State Psychiatric Institute, New York, New York, USA
    Graciela Penchaszadeh & T. Conrad Gilliam
  9. PsychoGenics Inc., Audubon Biomedical Science and Technology Park of Columbia University, New York, New York, USA
    Chang Choi & Andreas H. Kottmann

Authors

  1. Sergey Kalachikov
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  2. Oleg Evgrafov
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  3. Barbara Ross
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  4. Melodie Winawer
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  5. Christie Barker-Cummings
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  6. Filippo Martinelli Boneschi
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  7. Chang Choi
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  8. Pavel Morozov
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  9. Kamna Das
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  10. Elita Teplitskaya
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  11. Andrew Yu
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  12. Eftihia Cayanis
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  13. Graciela Penchaszadeh
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  14. Andreas H. Kottmann
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  15. Timothy A. Pedley
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  16. W. Allen Hauser
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  17. Ruth Ottman
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  18. T. Conrad Gilliam
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Corresponding author

Correspondence toRuth Ottman.

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Kalachikov, S., Evgrafov, O., Ross, B. et al. Mutations in LGI1 cause autosomal-dominant partial epilepsy with auditory features.Nat Genet 30, 335–341 (2002). https://doi.org/10.1038/ng832

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