Not a split decision for human hematopoiesis (original) (raw)
- News & Views
- Published: July 2010
Nature Immunology volume 11, pages 569–570 (2010)Cite this article
- 1205 Accesses
- 8 Citations
- Metrics details
Subjects
Hematopoietic lineage schemes commonly show two distinct lymphoid and myeloid branches arising from the hematopoietic stem cell early during blood cell development. A new study of human hematopoiesis demonstrates that, similar to findings in mice, this split is not as dichotomous as is often presented.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Additional access options:
Figure 1: Models of hematopoietic differentiation.
References
- Doulatov, S. et al. Nat. Immunol. 11, 585–593 (2010).
Article CAS Google Scholar - Abramson, S., Miller, R.G. & Phillips, R.A. J. Exp. Med. 145, 1567–1579 (1977).
Article CAS Google Scholar - Keller, G., Paige, C., Gilboa, E. & Wagner, E.F. Nature 318, 149–154 (1985).
Article CAS Google Scholar - Dick, J.E., Magli, M.C., Huszar, D., Phillips, R.A. & Bernstein, A. Cell 42, 71–79 (1985).
Article CAS Google Scholar - Fialkow, P.J., Denman, M.D., Jacobson, R.J. & Lowenthal, M.N. J. Clin. Invest. 62, 815–823 (1978).
Article CAS Google Scholar - Kondo, M. et al. Annu. Rev. Immunol. 21, 759–806 (2003).
Article CAS Google Scholar - Blom, B. & Spits, H. Annu. Rev. Immunol. 24, 287–320 (2006).
Article CAS Google Scholar - Katsura, Y. Nat. Rev. Immunol. 2, 127–132 (2002).
Article CAS Google Scholar - Adolfsson, J. et al. Cell 121, 295–306 (2005).
Article CAS Google Scholar - Baba, Y., Pelayo, R. & Kincade, P.W. Trends Immunol. 25, 645–649 (2004).
Article CAS Google Scholar - Payne, K.J. & Crooks, G.M. Immunity 26, 674–677 (2007).
Article CAS Google Scholar - Shizuru, J.A., Negrin, R.S. & Weissman, I. Annu. Rev. Med. 56, 509–538 (2005).
Article CAS Google Scholar
Author information
Authors and Affiliations
- Kenneth Dorshkind is in the Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.,
Kenneth Dorshkind
Authors
- Kenneth Dorshkind
You can also search for this author inPubMed Google Scholar
Corresponding author
Correspondence toKenneth Dorshkind.
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Dorshkind, K. Not a split decision for human hematopoiesis.Nat Immunol 11, 569–570 (2010). https://doi.org/10.1038/ni0710-569
- Issue Date: July 2010
- DOI: https://doi.org/10.1038/ni0710-569