Boosting p53 with interferon and viruses (original) (raw)

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• Published: 01 September 2003

Nature Immunology volume 4, pages 825–826 (2003)Cite this article

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Interferon-α/β proteins are vital for innate immune responses to viruses. The tumor suppressor p53 mediates cell cycle arrest and apoptosis. A recent study in Nature reports that interferon-α/β stimulates p53 synthesis, demonstrating a hitherto unrecognized link.

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Figure 1: Stimulation of p53 gene transcription by IFN-α/β and p53 activation by virus infection.

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Authors and Affiliations

1. New York University School of Medicine, New York, 10016, New York, USA
   Jan Vilček

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1. Jan Vilček
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Vilček, J. Boosting p53 with interferon and viruses.Nat Immunol 4, 825–826 (2003). https://doi.org/10.1038/ni0903-825

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• Issue Date: 01 September 2003
• DOI: https://doi.org/10.1038/ni0903-825

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