Costimulation and endogenous MHC ligands contribute to T cell recognition (original) (raw)
Monks, C. R., Freiberg, B. A., Kupfer, H., Sciaky, N. & Kupfer, A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature395, 82–86 (1998). ArticleCASPubMed Google Scholar
Grakoui, A. et al. The immunological synapse: A molecular machinery controlling T cell activation. Science285, 221–226 (1999). ArticleCASPubMed Google Scholar
Krummel, M. F., Sjaastad, M. D., Wülfing, C. & Davis, M. M. Differential clustering of CD4 and CD3ζ during T cell recognition. Science289, 1349–1352 (2000). ArticleCASPubMed Google Scholar
Wülfing, C., Bauch, A., Crabtree, G. R. & Davis, M. M. The vav exchange factor is an essential regulator in actin-dependent receptor translocation to the lymphocyte-antigen-presenting cell interface. Proc. Natl Acad. Sci. USA97, 10150–10155 (2000). ArticlePubMedPubMed Central Google Scholar
Dustin, M. L. & Shaw, A. S. Costimulation: building an immunological synapse. Science283, 649–650 (1999). ArticleCASPubMed Google Scholar
Kupfer, A. & Singer, S. J. Cell biology of cytotoxic and helper T cell functions: immunofluorescence microscopic studies of single cells and cell couples. Annu. Rev. Immunol.7, 309–337 (1989). ArticleCASPubMed Google Scholar
Singer, S. J. Intercellular communication and cell-cell adhesion. Science255, 1671–1677 (1992). ArticleCASPubMed Google Scholar
Wülfing, C. & Davis, M. M. A receptor/cytoskeletal movement triggered by costimulation during T cell activation. Science282, 2266–2270 (1998). ArticlePubMed Google Scholar
Viola, A., Schroeder, S., Sakakibara, Y. & Lanzavecchia, A. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science283, 680–682 (1999). ArticleCASPubMed Google Scholar
Blair, P. J. et al. CD28 co-receptor signal transduction in T-cell activation. Biochem. Soc. Trans.25, 651–657 (1997). ArticleCASPubMed Google Scholar
Chambers, C. A. & Allison, J. P. Co-stimulation in T cell responses. Curr. Opin. Immunol.9, 396–404 (1997). ArticleCASPubMed Google Scholar
Sperling, A. I. & Bluestone, J. A. The complexities of T-cell co-stimulation: CD28 and beyond. Immunol. Rev.153, 155–182 (1996). ArticleCASPubMed Google Scholar
Dustin, M. L. & Springer, T. A. T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1. Nature341, 619–624 (1989). ArticleCASPubMed Google Scholar
Stewart, M. & Hogg, N. Regulation of leukocyte integrin function: affinity vs. avidity. J. Cell. Biochem.61, 554–661 (1996). ArticleCASPubMed Google Scholar
van Kooyk, Y. & Figdor, C. G. Signalling and adhesive properties of the integrin leucocyte function-associated antigen 1 (LFA-1). Biochem. Soc. Trans.25, 515–520 (1997). ArticleCASPubMed Google Scholar
Boise, L. H. et al. CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL . Immunity3, 87–98 (1995). ArticleCASPubMed Google Scholar
Shapiro, V. S., Mollenauer, M. N. & Weiss, A. Nuclear factor of activated T cells and AP-1 are insufficient for IL-2 promoter activation: requirement for CD28 up-regulation of RE/AP. J. Immunol.161, 6455–6458 (1998). CASPubMed Google Scholar
Davis, M. M., Chien, Y. H., Gascoigne, N. R. & Hedrick, S. M. A murine T cell receptor gene complex: isolation, structure and rearrangement. Immunol. Rev.81, 235–258 (1984). ArticleCASPubMed Google Scholar
Lo, D., Ron, Y. & Sprent, J. Induction of MHC-restricted specificity and tolerance in the thymus. Immunol. Res.5, 221–232 (1986). ArticleCASPubMed Google Scholar
Goldrath, A. W. & Bevan, M. J. Selecting and maintaining a diverse T-cell repertoire. Nature402, 255–262 (1999). ArticleCASPubMed Google Scholar
Tanchot, C., Lemonnier, F. A., Pérarnau, B., Freitas, A. A. & Rocha, B. Differential requirements for survival and proliferation of CD8 naïve or memory T cells. Science276, 2057–2062 (1997). ArticleCASPubMed Google Scholar
Takeda, S., Rodewald, H. R., Arakawa, H., Bluethmann, H. & Shimizu, T. MHC class II molecules are not required for survival of newly generated CD4+ T cells, but affect their long-term life span. Immunity5, 217–228 (1996). ArticleCASPubMed Google Scholar
Brocker, T. Survival of mature CD4 T lymphocytes is dependent on major histocompatibility complex class II-expressing dendritic cells. J. Exp. Med.186, 1223–1232 (1997). ArticleCASPubMedPubMed Central Google Scholar
Rooke, R., Waltzinger, C., Benoist, C. & Mathis, D. Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses. Immunity7, 123–134 (1997). ArticleCASPubMed Google Scholar
Motyka, B. & Teh, H. S. Naturally occurring low affinity peptide-MHC class I ligands can mediate negative selection and T cell activation. J. Immunol.160, 77–86 (1998). CASPubMed Google Scholar
Williams, C. B., Engle, D. L., Kersh, G. J., Michael White, J. & Allen, P. M. A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex. J. Exp. Med.189, 1531–1544 (1999). ArticleCASPubMedPubMed Central Google Scholar
Berg, L. J. et al. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell58, 1035–1046 (1989). ArticleCASPubMed Google Scholar
Seder, R. A., Paul, W. E., Davis, M. M. & Fazekas de St. Groth, B. The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice. J. Exp. Med.176, 1091–1098 (1992). ArticleCASPubMed Google Scholar
Wülfing, C., Sjaastad, M. D. & Davis, M. M. Visualizing the dynamics of T cell activation: ICAM-1 migrates rapidly to the T cell:B cell interface and acts to sustain calcium levels. Proc. Natl Acad. Sci. USA95, 6302–6307 (1998). ArticlePubMedPubMed Central Google Scholar
Wubbolts, R. et al. Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface. J. Cell Biol.135, 611–622 (1996). ArticleCASPubMed Google Scholar
Reay, P. A., Kantor, R. M. & Davis, M. M. Use of global amino acid replacements to define the requirements for MHC binding and T cell recognition of moth cytochrome c (93–103). J. Immunol.152, 3946–3957 (1994). CASPubMed Google Scholar
Lyons, D. S. et al. A T cell receptor binds to antagonist ligands with lower affinities and faster dissociation rates than to agonists. Immunity5, 53–61 (1996). ArticleCASPubMed Google Scholar
Wülfing, C. et al. Kinetics and extent of T cell activation as measured with the calcium signal. J. Exp. Med.185, 1815–1825 (1997). ArticlePubMedPubMed Central Google Scholar
Valitutti, S., Dessing, M., Aktories, K., Gallati, H. & Lanzavecchia, A. Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. J. Exp. Med.181, 577–584 (1995). ArticleCASPubMed Google Scholar
Holsinger, L. J. et al. Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction. Curr. Biol.8, 563–572 (1998). ArticleCASPubMed Google Scholar
Konig, R., Huang, L. Y. & Germain, R. N. MHC class II interaction with CD4 mediated by a region analogous to the MHC class I binding site for CD8. Nature356, 796–798 (1992). ArticleCASPubMed Google Scholar
Cammarota, G. et al. Identification of a CD4 binding site on the β2 domain of HLA-DR molecules. Nature356, 799–801 (1992). ArticleCASPubMed Google Scholar
Jorgensen, J. L., Esser, U., Fazekas de St. Groth, B., Reay, P. A. & Davis, M. M. Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature355, 224–230 (1992). ArticleCASPubMed Google Scholar
Glimcher, L. H. & Kara, C. J. Sequences and factors: a guide to MHC class-II transcription. Annu. Rev. Immunol.10, 13–49 (1992). ArticleCASPubMed Google Scholar
Mach, B., Steimle, V., Martinez-Soria, E. & Reith, W. Regulation of MHC class II genes: lessons from a disease. Annu. Rev. Immunol.14, 301–331 (1996). ArticleCASPubMed Google Scholar
Davis, S. J. & van der Merwe, P.A. The structure and ligand interactions of CD2: implications for T-cell function. Immunol. Today17 177–187 (1996). ArticleCASPubMed Google Scholar
Al-Alwan, M. M., Rowden, G., Lee, T. D. & West, K. A. The dendritic cell cytoskeleton is critical for the formation of the immunological synapse. J. Immunol.166, 1452–1456 (2001). ArticleCASPubMed Google Scholar
Manning, T. C. et al. Alanine scanning mutagenesis of an αβ T cell receptor: mapping the energy of antigen recognition. Immunity8, 413–425 (1998). ArticleCASPubMed Google Scholar
Sandberg, J. K., Kärre, K. & Glas, R. Recognition of the major histocompatibility complex restriction element modulates CD8(+) T cell specificity and compensates for loss of T cell receptor contacts with the specific peptide. J. Exp. Med.189, 883–894 (1999). ArticleCASPubMedPubMed Central Google Scholar
Anderson, M. T. et al. Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins. Proc. Natl Acad. Sci. USA93, 8508–8011 (1996). ArticleCASPubMedPubMed Central Google Scholar
Wettstein, D. A., Boniface, J. J., Reay, P. A., Schild, H. & Davis, M. M. Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH. J. Exp. Med.174, 219–228 (1991). ArticleCASPubMed Google Scholar
Yelon, D., Schaefer, K. L. & Berg, L. J. Alterations in CD4-binding regions of the MHC class II molecule I-Ek do not impede CD4+ T cell development. J. Immunol.162, 1348–1358 (1999). CASPubMed Google Scholar
Riberdy, J. M., Mostaghel, E. & Doyle, C. Disruption of the CD4-major histocompatibility complex class II interaction blocks the development of CD4(+) T cells in vivo. Proc. Natl Acad. Sci. USA95, 4493–4498 (1998). ArticleCASPubMedPubMed Central Google Scholar
Mostaghel, E. A., Riberdy, J. M., Steeber, D. A. & Doyle, C. Coreceptor-independent T cell activation in mice expressing MHC class II molecules mutated in the CD4 binding domain. J. Immunol.161, 6559–6566 (1998). CASPubMed Google Scholar
Gilfillan, S., Shen, X. & König, R. Selection and function of CD4+ T lymphocytes in transgenic mice expressing mutant MHC class II molecules deficient in their interaction with CD4. J. Immunol.161, 6629–6637 (1998). CASPubMed Google Scholar
Baldwin, K. K., Reay, P. A., Wu, L., Farr, A. & Davis, M. M. A T cell receptor-specific blockade of positive selection. J. Exp. Med.189, 13–24 (1999). ArticleCASPubMedPubMed Central Google Scholar
Kimachi, K., Croft, M. & Grey, H. M. The minimal number of antigen-major histocompatibility complex class II complexes required for activation of naive and primed T cells. Eur. J. Immunol.27, 3310–3317 (1997). ArticleCASPubMed Google Scholar
Dadaglio, G., Nelson, C. A., Deck, M. B., Petzold, S. J. & Unanue, E. R. Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody. Immunity6, 727–738 (1997). ArticleCASPubMed Google Scholar
Chan, P. Y. et al. Influence of receptor lateral mobility on adhesion strengthening between membranes containing LFA-3 and CD2. J. Cell Biol.115, 245–255 (1991). ArticleCASPubMed Google Scholar