Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche (original) (raw)

• Li, L. & Xie, T. Stem cell niche: structure and function. Annu. Rev. Cell Dev. Biol. 21, 605–631 (2005).
  Article CAS Google Scholar
• Barker, N., van de Wetering, M. & Clevers, H. The intestinal stem cell. Genes Dev. 22, 1856–1864 (2008).
  Article CAS Google Scholar
• Potten, C.S., Booth, C. & Pritchard, D.M. The intestinal epithelial stem cell: the mucosal governor. Int. J. Exp. Pathol. 78, 219–243 (1997).
  Article CAS Google Scholar
• Barker, N. et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003–1007 (2007).
  Article CAS Google Scholar
• Sangiorgi, E. & Capecchi, M.R. Bmi1 is expressed in vivo in intestinal stem cells. Nat. Genet. 40, 915–920 (2008).
  Article CAS Google Scholar
• Scoville, D.H., Sato, T., He, X.C. & Li, L. Current view: intestinal stem cells and signaling. Gastroenterology 134, 849–864 (2008).
  Article CAS Google Scholar
• Cheng, H. & Leblond, C.P. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types. Am. J. Anat. 141, 537–561 (1974).
  Article CAS Google Scholar
• Scadden, D.T. The stem-cell niche as an entity of action. Nature 441, 1075–1079 (2006).
  Article CAS Google Scholar
• Crosnier, C., Stamataki, D. & Lewis, J. Organizing cell renewal in the intestine: stem cells, signals and combinatorial control. Nat. Rev. Genet. 7, 349–359 (2006).
  Article CAS Google Scholar
• Williams, E.D., Lowes, A.P., Williams, D. & Williams, G.T. A stem cell niche theory of intestinal crypt maintenance based on a study of somatic mutation in colonic mucosa. Am. J. Pathol. 141, 773–776 (1992).
  CAS PubMed PubMed Central Google Scholar
• Pinto, D., Gregorieff, A., Begthel, H. & Clevers, H. Canonical Wnt signals are essential for homeostasis of the intestinal epithelium. Genes Dev. 17, 1709–1713 (2003).
  Article CAS Google Scholar
• Kuhnert, F. et al. Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1. Proc. Natl. Acad. Sci. USA 101, 266–271 (2004).
  Article CAS Google Scholar
• van Es, J.H. et al. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435, 959–963 (2005).
  Article CAS Google Scholar
• Fre, S. et al. Notch signals control the fate of immature progenitor cells in the intestine. Nature 435, 964–968 (2005).
  Article CAS Google Scholar
• Pageot, L.P. et al. Human cell models to study small intestinal functions: recapitulation of the crypt-villus axis. Microsc. Res. Tech. 49, 394–406 (2000).
  Article CAS Google Scholar
• Kaeffer, B. Mammalian intestinal epithelial cells in primary culture: a mini-review. In Vitro Cell. Dev. Biol. Anim. 38, 123–134 (2002).
  Article Google Scholar
• Bjerknes, M. & Cheng, H. Intestinal epithelial stem cells and progenitors. Methods Enzymol. 419, 337–383 (2006).
  Article CAS Google Scholar
• Frisch, S.M. & Francis, H. Disruption of epithelial cell-matrix interactions induces apoptosis. J. Cell Biol. 124, 619–626 (1994).
  Article CAS Google Scholar
• Sträter, J. et al. Rapid onset of apoptosis in vitro follows disruption of β1-integrin/matrix interactions in human colonic crypt cells. Gastroenterology 110, 1776–1784 (1996).
  Article Google Scholar
• Booth, C., O'Shea, J.A. & Potten, C.S. Maintenance of functional stem cells in isolated and cultured adult intestinal epithelium. Exp. Cell Res. 249, 359–366 (1999).
  Article CAS Google Scholar
• Perreault, N. & Beaulieu, J.F. Primary cultures of fully differentiated and pure human intestinal epithelial cells. Exp. Cell Res. 245, 34–42 (1998).
  Article CAS Google Scholar
• Abud, H.E., Watson, N. & Heath, J.K. Growth of intestinal epithelium in organ culture is dependent on EGF signalling. Exp. Cell Res. 303, 252–262 (2005).
  Article CAS Google Scholar
• Blanpain, C., Horsley, V. & Fuchs, E. Epithelial stem cells: turning over new leaves. Cell 128, 445–458 (2007).
  Article CAS Google Scholar
• Kim, K.A. et al. Mitogenic influence of human R-spondin1 on the intestinal epithelium. Science 309, 1256–1259 (2005).
  Article CAS Google Scholar
• Milano, J. et al. Modulation of notch processing by γ-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. Toxicol. Sci. 82, 341–358 (2004).
  Article CAS Google Scholar
• Schonhoff, S.E., Giel-Moloney, M. & Leiter, A.B. Neurogenin 3–expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types. Dev. Biol. 270, 443–454 (2004).
  Article CAS Google Scholar
• López-Díaz, L. et al. Intestinal neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate. Dev. Biol. 309, 298–305 (2007).
  Article Google Scholar
• Wang, J. et al. Mutant neurogenin-3 in congenital malabsorptive diarrhea. N. Engl. J. Med. 355, 270–280 (2006).
  Article CAS Google Scholar
• Schmidt, G.H., Winton, D.J. & Ponder, B.A. Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine. Development 103, 785–790 (1988).
  CAS PubMed Google Scholar
• Ueno, H. & Weissman, I.L. Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands. Dev. Cell 11, 519–533 (2006).
  Article CAS Google Scholar
• Griffith, L.G. & Swartz, M.A. Capturing complex 3D tissue physiology in vitro. Nat. Rev. Mol. Cell Biol. 7, 211–224 (2006).
  Article CAS Google Scholar
• Yamada, K.M. & Cukierman, E. Modeling tissue morphogenesis and cancer in 3D. Cell 130, 601–610 (2007).
  Article CAS Google Scholar
• Bryant, D.M. & Mostov, K.E. From cells to organs: building polarized tissue. Nat. Rev. Mol. Cell Biol. 9, 887–901 (2008).
  Article CAS Google Scholar
• Nelson, C.M. & Bissell, M.J. Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. Annu. Rev. Cell Dev. Biol. 22, 287–309 (2006).
  Article CAS Google Scholar
• Pampaloni, F., Reynaud, E.G. & Stelzer, E.H. The third dimension bridges the gap between cell culture and live tissue. Nat. Rev. Mol. Cell Biol. 8, 839–845 (2007).
  Article CAS Google Scholar
• Bingmann, D. & Kolde, G. PO2-profiles in hippocampal slices of the guinea pig. Exp. Brain Res. 48, 89–96 (1982).
  Article CAS Google Scholar
• Pruniéras, M., Regnier, M. & Woodley, D. Methods for cultivation of keratinocytes with an air-liquid interface. J. Invest. Dermatol. 81, 28s–33s (1983).
  Article Google Scholar
• Toda, S. et al. A new organotypic culture of thyroid tissue maintains three-dimensional follicles with C cells for a long term. Biochem. Biophys. Res. Commun. 294, 906–911 (2002).
  Article CAS Google Scholar
• Ootani, A., Toda, S., Fujimoto, K. & Sugihara, H. Foveolar differentiation of mouse gastric mucosa in vitro. Am. J. Pathol. 162, 1905–1912 (2003).
  Article Google Scholar
• Amemori, S. et al. Adipocytes and preadipocytes promote the proliferation of colon cancer cells in vitro. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G923–G929 (2007).
  Article CAS Google Scholar