Expression and function of CCR5 and CXCR4 on human Langerhans cells and macrophages: Implications for HIV primary infection (original) (raw)
Zhu, T. et al. Genotypic and phenotypic characterization of HIV-1 in patients with primary infection. Science261, 1179–1181 (1993). ArticleCASPubMed Google Scholar
Wolinsky, S.M. et al. Selective transmission of human immunodeficiency virus type 1 variants from mothers to infants. Science255, 1134–1137 (1992). ArticleCASPubMed Google Scholar
Zhu, T. et al. Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: Evidence for viral compartmentalization and selection during sexual transmission. J. Vlrol.70, 3098–3107 (1996). CAS Google Scholar
Zhang, L. et al. Selection for specific sequences in the external envelope protein of human immunodeficiency virus type 1 upon primary infection. J. Virol.67, 3354–3356 (1993). Google Scholar
van't Wout, A.B. et al. Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission. J. Clin. Invest.94, 2060–2067 (1994). ArticleCASPubMedPubMed Central Google Scholar
Blauvelt, A. The role of skin dendritic cells in the initiation of HIV infection. Am. J. Med.102(5B), 16–20 (1997). ArticleCASPubMed Google Scholar
Cameron, P., Pope, M., Granelli-Piperno, A. & Steinman, R.M. Dendritic cells and the replication of HIV-1. J. Leukocyte Biol.59, 158–171 (1996). ArticleCASPubMed Google Scholar
Zambruno, G., Gianetti, A., Bertazzoni, U. & Girolomoni, G. Langerhans cells and HIV-1 infection. Immunol. Today16, 520–524 (1995). ArticleCASPubMed Google Scholar
Spira, A.I. et al. Cellular targets of infection and route of viral dissemination after an in-travaginal inoculation of simian immunodeficiency virus into rhesus macaques. J. Exp. Med.183, 215–225 (1996). ArticleCASPubMed Google Scholar
Miller, C.J. et al. Mechanism of genital transmission of SIV: A hypothesis based on transmission studies and the location of SIV in the genital tract of chronically infected female rhesus macaques. J. Med. Primatol.21, 64–68 (1992). CASPubMed Google Scholar
Granelli-Piperno, A. et al. Efficient interaction of HIV-1 with purified dendritic cells via multiple chemokine receptors. J. Exp. Med.184, 2433–2438 (1996). ArticleCASPubMedPubMed Central Google Scholar
Blauvelt, A. et al. Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways. J. Clin. Invest.100, 2043–2053 (1997). ArticleCASPubMedPubMed Central Google Scholar
Pope, M. et al. Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1. Cell78, 389–398 (1994). ArticleCASPubMed Google Scholar
Pope, M. et al. Low levels of HIV-1 infection in cutaneous dendritic cells promote extensive viral replication upon binding to memory CD4+ T cells. J. Exp. Med.182, 2045–2056 (1995). ArticleCASPubMed Google Scholar
Soto-Ramirez, L.E. et al. HIV-1 Langerhans cell tropism associated with heterosexual transmission of HIV. Science271, 1291–1293 (1996). ArticleCASPubMed Google Scholar
Steinman, R.M. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol.9, 271–276 (1991). ArticleCASPubMed Google Scholar
Romani, N. et al. Cultured human Langerhans ceils resemble lymphoid dendritic cells in phenotype and function. J. Invest. Dermatol.93, 600–609 (1989). ArticleCASPubMed Google Scholar
Romani, N. & Schuler, G. The immunologic properties of epidermal Langerhans cells as part of the dendritic cell system. Springer Semin. Immunopathol.13, 265–279 (1992). ArticleCASPubMed Google Scholar
Sallusto, F. & Lanzavecchia, A. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J. Exp. Med.179, 1109–1118 (1994). ArticleCASPubMed Google Scholar
Romani, N. et al. Proliferating dendritic cell progenitors in human blood. J. Exp. Med.180, 83–93 (1994). ArticleCASPubMed Google Scholar
Aiba, S. & Katz, S.I. Phenotypic and functional characteristics of in vivo-activated Langerhans ceils. J. Immunol.145, 2791–2796 (1990). CASPubMed Google Scholar
Kripke, M.L., Dunn, C.G., Jeevan, A., Tang, J. & Bucana, C. Evidence that cutaneous antigen-presenting cells migrate to regional lymph nodes during contact sensitization. J. Immunol.145, 2833–2838 (1990). CASPubMed Google Scholar
Parr, M.B., Kepple, L. & Parr, E.L. Antigen recognition in the reproductive tract. II. Endocytosis of horseradish peroxidase by Langerhans cells in murine vaginal epithelium. Biol. Reprod.45, 261–265 (1991). ArticleCASPubMed Google Scholar
Edwards, J.N.T. & Morris, H.B. Langerhans' cells and lymphocyte subsets in the female genital tract. Br. J. Obstet. Gynecol.92, 974–982 (1985). ArticleCAS Google Scholar
Miller, C.J., McGee, J.R. & Gardner, M.B. Biology of disease: Mucosal immunity, HIV transmission, and AIDS. Lab. Invest.68, 129–145 (1993). CASPubMed Google Scholar
Miller, C.J., McChesney, M. & Moore, P.F. Langerhans cells, macrophages, and lymphocyte subsets in the cervix and vagina of rhesus macaques. Lab. Invest.67, 628–634 (1992). CASPubMed Google Scholar
Lapham, C.K. et al. Evidence for cell-surface association between fusin and the CD4-gpl20 complex in human cell lines. Science274, 602–605 (1996). ArticleCASPubMed Google Scholar
Lusso, P. et al. Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4+ T-cell clone (PM1): Failure to downregulate CD4 and to interfere with T-cell-line-tropic HIV-1. J. Virol.69, 3712–3720 (1995). CASPubMedPubMed Central Google Scholar
Endres, M.J. et al. CD4-independent infection by HIV-2 is mediated by CXCR-4. Cell87, 745–756 (1996). ArticleCASPubMed Google Scholar
Blauvelt, A. et al. Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons. J. Immunol.154, 3506–3515 (1995). CASPubMed Google Scholar
Broder, C.C., Dimitrov, D.S., Blumenthal, R. & Berger, E.A. The block to HIV-1 envelope glycoprotein-mediated membrane fusion in animal cells expressing human CD4 can be overcome by human cell components. Virology193, 483–491 (1993). ArticleCASPubMed Google Scholar
Pomerantz, R. et al. Human immunodeficiency virus (HIV) infection of the uterine cervix. Ann. Intern. Med.108, 321–327 (1988). ArticleCASPubMed Google Scholar
Nuovo, G., Forde, G., MacConnell, P. & Fahrenwald, R. In situ detection of PCR-ampli-fied HIV-1 nucleic acid and tumor necrosis factor cDNA in cervical tissues. Am. J. Pathol.143, 40–48 (1993). CASPubMedPubMed Central Google Scholar
Howell, A.L. et al. Human immunodeficiency virus type 1 infection of cells and tissues from the upper and lower human female reproductive tract. J. Virol.71, 3498–3506 (1997). CASPubMedPubMed Central Google Scholar
Macatonia, S.E., Patterson, S. & Knight, S.C. Suppression of immune responses by dendritic cells infected with HIV. Immunology67, 285–289 (1989). CASPubMedPubMed Central Google Scholar
Cameron, P.U. et al. Dendritic cells exposed to human immunodeficiency virus type 1 transmit a vigorous infection to CD4+ T cells. Science257, 383–387 (1992). ArticleCASPubMed Google Scholar
Weissman, D. et al. Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1. Proc. Natl: Acad. Sci. USA92, 826–830 (1995). ArticleCAS Google Scholar
Berger, E.A. HIV entry and tropism: The chemokine receptor connection. AIDS11 (Suppl. A) S3–S16 (1997). PubMed Google Scholar
Orenstein, J.M., Fox, C. & Wahl, S. Macrophages as a source of HIV during opportunistic infections. Science276, 1857–1861 (1997). ArticleCASPubMed Google Scholar
Cameron, P.U. et al. The interaction of macrophage and non-macrophage tropic isolates of HIV-1 with thymic and tonsillar dendritic cells in vitro. J. Exp. Med.183, 1851–1856 (1996). ArticleCASPubMed Google Scholar
Liu, R. et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell86, 367–377 (1996). ArticleCASPubMed Google Scholar
Dean, M. et al. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CCR5 structural gene. Science273, 1856–1862 (1996). ArticleCASPubMed Google Scholar
Casamayor-Palleja, M., Khan, M. & MacLennan, I.C.M. A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex. J. Exp. Med.181, 1293–1301 (1995). ArticleCASPubMed Google Scholar