A thermosensory pathway that controls body temperature (original) (raw)

• Hammel, H.T. Regulation of internal body temperature. Annu. Rev. Physiol. 30, 641–710 (1968).
  Article CAS Google Scholar
• Hensel, H. Thermoreception and temperature regulation. Monogr. Physiol. Soc. 38, 1–321 (1981).
  CAS PubMed Google Scholar
• Boulant, J.A. & Gonzalez, R.R. The effect of skin temperature on the hypothalamic control of heat loss and heat production. Brain Res. 120, 367–372 (1977).
  Article CAS Google Scholar
• Nagashima, K., Nakai, S., Tanaka, M. & Kanosue, K. Neuronal circuitries involved in thermoregulation. Auton. Neurosci. 85, 18–25 (2000).
  Article CAS Google Scholar
• Nakamura, K. & Morrison, S.F. Central efferent pathways mediating skin cooling-evoked sympathetic thermogenesis in brown adipose tissue. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R127–R136 (2007).
  Article CAS Google Scholar
• Romanovsky, A.A. Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory system. Am. J. Physiol. Regul. Integr. Comp. Physiol. 292, R37–R46 (2007).
  Article CAS Google Scholar
• Huckaba, C.E., Downey, J.A. & Darling, R.C. A feedback-feedforward mechanism describing the interaction of central and peripheral signals in human thermoregulation. Int. J. Biometeorol. 15, 141–145 (1971).
  Article CAS Google Scholar
• Savage, M.V. & Brengelmann, G.L. Control of skin blood flow in the neutral zone of human body temperature regulation. J. Appl. Physiol. 80, 1249–1257 (1996).
  Article CAS Google Scholar
• Craig, A.D., Bushnell, M.C., Zhang, E-T. & Blomqvist, A. A thalamic nucleus specific for pain and temperature sensation. Nature 372, 770–773 (1994).
  Article CAS Google Scholar
• Craig, A.D. How do you feel? Interoception: the sense of the physiological condition of the body. Nat. Rev. Neurosci. 3, 655–666 (2002).
  Article CAS Google Scholar
• Sagar, S.M., Sharp, F.R. & Curran, T. Expression of c-fos protein in brain: metabolic mapping at the cellular level. Science 240, 1328–1331 (1988).
  Article CAS Google Scholar
• Saper, C.B. & Loewy, A.D. Efferent connections of the parabrachial nucleus in the rat. Brain Res. 197, 291–317 (1980).
  Article CAS Google Scholar
• Fulwiler, C.E. & Saper, C.B. Subnuclear organization of the efferent connections of the parabrachial nucleus in the rat. Brain Res. Rev. 7, 229–259 (1984).
  Article Google Scholar
• Krukoff, T.L., Harris, K.H. & Jhamandas, J.H. Efferent projections from the parabrachial nucleus demonstrated with the anterograde tracer Phaseolus vulgaris leucoagglutinin. Brain Res. Bull. 30, 163–172 (1993).
  Article CAS Google Scholar
• Bester, H., Besson, J-M. & Bernard, J-F. Organization of efferent projections from the parabrachial area to the hypothalamus: a _Phaseolus vulgaris_-leucoagglutinin study in the rat. J. Comp. Neurol. 383, 245–281 (1997).
  Article CAS Google Scholar
• Lumpkin, E.A. & Caterina, M.J. Mechanisms of sensory transduction in the skin. Nature 445, 858–865 (2007).
  Article CAS Google Scholar
• Cechetto, D.F., Standaert, D.G. & Saper, C.B. Spinal and trigeminal dorsal horn projections to the parabrachial nucleus in the rat. J. Comp. Neurol. 240, 153–160 (1985).
  Article CAS Google Scholar
• Bernard, J.-F., Dallel, R., Raboisson, P., Villanueva, L. & Le Bars, D. Organization of the efferent projections from the spinal cervical enlargement to the parabrachial area and periaqueductal gray: a PHA-L study in the rat. J. Comp. Neurol. 353, 480–505 (1995).
  Article CAS Google Scholar
• Feil, K. & Herbert, H. Topographic organization of spinal and trigeminal somatosensory pathways to the rat parabrachial and Kölliker-Fuse nuclei. J. Comp. Neurol. 353, 506–528 (1995).
  Article CAS Google Scholar
• Bester, H., Menendez, L., Besson, J.M. & Bernard, J.F. Spino(trigemino)parabrachiohypothalamic pathway: electrophysiological evidence for an involvement in pain processes. J. Neurophysiol. 73, 568–585 (1995).
  Article CAS Google Scholar
• Johnston, G.A.R. GABAA receptor pharmacology. Pharmacol. Ther. 69, 173–198 (1996).
  Article CAS Google Scholar
• Nakamura, K. et al. The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area. J. Neurosci. 22, 4600–4610 (2002).
  Article CAS Google Scholar
• Madden, C.J. & Morrison, S.F. Excitatory amino acid receptor activation in the raphe pallidus area mediates prostaglandin-evoked thermogenesis. Neuroscience 122, 5–15 (2003).
  Article CAS Google Scholar
• Zaretskaia, M.V., Zaretsky, D.V. & DiMicco, J.A. Role of the dorsomedial hypothalamus in thermogenesis and tachycardia caused by microinjection of prostaglandin E2 into the preoptic area in anesthetized rats. Neurosci. Lett. 340, 1–4 (2003).
  Article CAS Google Scholar
• Madden, C.J. & Morrison, S.F. Excitatory amino acid receptors in the dorsomedial hypothalamus mediate prostaglandin-evoked thermogenesis in brown adipose tissue. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286, R320–R325 (2004).
  Article CAS Google Scholar
• Nakamura, K. Fever-inducing sympathetic neural pathways. J. Therm. Biol. 29, 339–344 (2004).
  Article CAS Google Scholar
• Nakamura, K., Matsumura, K., Kobayashi, S. & Kaneko, T. Sympathetic premotor neurons mediating thermoregulatory functions. Neurosci. Res. 51, 1–8 (2005).
  Article Google Scholar
• Nakamura, Y. et al. Direct pyrogenic input from prostaglandin EP3 receptor–expressing preoptic neurons to the dorsomedial hypothalamus. Eur. J. Neurosci. 22, 3137–3146 (2005).
  Article Google Scholar
• Gauriau, C. & Bernard, J.-F. A comparative reappraisal of projections from the superficial laminae of the dorsal horn in the rat: the forebrain. J. Comp. Neurol. 468, 24–56 (2004).
  Article Google Scholar
• Zhang, X., Davidson, S. & Giesler, G.J., Jr. Thermally identified subgroups of marginal zone neurons project to distinct regions of the ventral posterior lateral nucleus in rats. J. Neurosci. 26, 5215–5223 (2006).
  Article CAS Google Scholar
• Kobayashi, A. & Osaka, T. Involvement of the parabrachial nucleus in thermogenesis induced by environmental cooling in the rat. Pflugers Arch. 446, 760–765 (2003).
  Article CAS Google Scholar
• Hylden, J.L.K., Anton, F. & Nahin, R.L. Spinal lamina I projection neurons in the rat: collateral innervation of parabrachial area and thalamus. Neuroscience 28, 27–37 (1989).
  Article CAS Google Scholar
• Broman, J. & Ottersen, O.P. Cervicothalamic tract terminals are enriched in glutamate-like immunoreactivity: an electron microscopic double-labeling study in the cat. J. Neurosci. 12, 204–221 (1992).
  Article CAS Google Scholar
• Blomqvist, A., Ericson, A.C., Craig, A.D. & Broman, J. Evidence for glutamate as a neurotransmitter in spinothalamic tract terminals in the posterior region of owl monkeys. Exp. Brain Res. 108, 33–44 (1996).
  Article CAS Google Scholar
• Bratincsák, A. & Palkovits, M. Evidence that peripheral rather than intracranial thermal signals induce thermoregulation. Neuroscience 135, 525–532 (2005).
  Article Google Scholar
• Chen, X.-M., Hosono, T., Yoda, T., Fukuda, Y. & Kanosue, K. Efferent projection from the preoptic area for the control of non-shivering thermogenesis in rats. J. Physiol. (Lond.) 512, 883–892 (1998).
  Article CAS Google Scholar
• Nakamura, K. et al. Immunocytochemical localization of prostaglandin EP3 receptor in the rat hypothalamus. Neurosci. Lett. 260, 117–120 (1999).
  Article CAS Google Scholar
• Lazarus, M. et al. EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses. Nat. Neurosci. 10, 1131–1133 (2007).
  Article CAS Google Scholar
• Bester, H., Chapman, V., Besson, J.-M. & Bernard, J.-F. Physiological properties of the lamina I spinoparabrachial neurons in the rat. J. Neurophysiol. 83, 2239–2259 (2000).
  Article CAS Google Scholar
• Craig, A.D. & Dostrovsky, J.O. Differential projections of thermoreceptive and nociceptive lamina I trigeminothalamic and spinothalamic neurons in the cat. J. Neurophysiol. 86, 856–870 (2001).
  Article CAS Google Scholar
• Boulant, J.A. & Hardy, J.D. The effect of spinal and skin temperatures on the firing rate and thermosensitivity of preoptic neurones. J. Physiol. (Lond.) 240, 639–660 (1974).
  Article CAS Google Scholar
• Hellon, R.F., Hensel, H. & Schäfer, K. Thermal receptors in the scrotum of the rat. J. Physiol. (Lond.) 248, 349–357 (1975).
  Article CAS Google Scholar
• Saper, C.B. The central autonomic nervous system: conscious visceral perception and autonomic pattern generation. Annu. Rev. Neurosci. 25, 433–469 (2002).
  Article CAS Google Scholar
• Hori, T., Nakashima, T., Koga, H., Kiyohara, T. & Inoue, T. Convergence of thermal, osmotic and cardiovascular signals on preoptic and anterior hypothalamic neurons in the rat. Brain Res. Bull. 20, 879–885 (1988).
  Article CAS Google Scholar
• Morrison, S.F. Central pathways controlling brown adipose tissue thermogenesis. News Physiol. Sci. 19, 67–74 (2004).
  Google Scholar
• Nakamura, K. et al. Identification of sympathetic premotor neurons in medullary raphe regions mediating fever and other thermoregulatory functions. J. Neurosci. 24, 5370–5380 (2004).
  Article CAS Google Scholar
• Nakamura, K. et al. Immunohistochemical localization of prostaglandin EP3 receptor in the rat nervous system. J. Comp. Neurol. 421, 543–569 (2000).
  Article CAS Google Scholar
• Nakamura, K., Li, Y.-Q., Kaneko, T., Katoh, H. & Negishi, M. Prostaglandin EP3 receptor protein in serotonin and catecholamine cell groups: a double immunofluorescence study in the rat brain. Neuroscience 103, 763–775 (2001).
  Article CAS Google Scholar
• Morrison, S.F. & Cao, W.-H. Different adrenal sympathetic preganglionic neurons regulate epinephrine and norepinephrine secretion. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279, R1763–R1775 (2000).
  Article CAS Google Scholar
• Pinault, D. A novel single-cell staining procedure performed in vivo under electrophysiological control: morpho-functional features of juxtacellularly labeled thalamic cells and other central neurons with biocytin or Neurobiotin. J. Neurosci. Methods 65, 113–136 (1996).
  Article CAS Google Scholar