A transient receptor potential channel expressed in taste receptor cells (original) (raw)

• Gilbertson, T.A., Damak, S. & Margolskee, R.F. The molecular physiology of taste transduction. Curr. Opin. Neurobiol. 10, 519–527 (2000).
  Article CAS Google Scholar
• Lindemann, B. Receptors and transduction in taste. Nature 413, 219–225 (2001).
  Article CAS Google Scholar
• Adler, E. et al. A novel family of mammalian taste receptors. Cell 100, 693–702 (2000).
  Article CAS Google Scholar
• Matsunami, H., Montmayeur, J.P. & Buck, L.B. A family of candidate taste receptors in human and mouse. Nature 404, 601–604 (2000).
  Article CAS Google Scholar
• Chandrashekar, J. et al. T2Rs function as bitter taste receptors. Cell 100, 703–711 (2000).
  Article CAS Google Scholar
• Bachmanov, A.A. et al. Positional cloning of the mouse saccharin preference (Sac) locus. Chem. Senses 26, 925–933 (2001).
  Article CAS Google Scholar
• Nelson, G. et al. Mammalian sweet taste receptors. Cell 106, 381–390 (2001).
  Article CAS Google Scholar
• Sainz, E., Korley, J.N., Battey, J.F. & Sullivan, S.L. Identification of a novel member of the T1R family of putative taste receptors. J. Neurochem. 77, 896–903 (2001).
  Article CAS Google Scholar
• Max, M. et al. Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus. Sac. Nat. Genet. 28, 58–63 (2001).
  CAS PubMed Google Scholar
• Montmayeur, J.P., Liberles, S.D., Matsunami, H. & Buck, L.B. A candidate taste receptor gene near a sweet taste locus. Nat. Neurosci. 4, 492–498 (2001).
  Article CAS Google Scholar
• Kitagawa, M., Kusakabe, Y., Miura, H., Ninomiya, Y. & Hino, A. Molecular genetic identification of a candidate receptor gene for sweet taste. Biochem. Biophys. Res. Commun. 283, 236–242 (2001).
  Article CAS Google Scholar
• Chaudhari, N., Landin, A.M. & Roper, S.D. A metabotropic glutamate receptor variant functions as a taste receptor. Nat. Neurosci. 3, 113–119 (2000).
  Article CAS Google Scholar
• Nelson, G. et al. An amino-acid taste receptor. Nature 416, 199–202 (2002).
  Article CAS Google Scholar
• McLaughlin, S.K., McKinnon, P.J. & Margolskee, R.F. Gustducin is a taste-cell–specific G protein closely related to the transducins. Nature 357, 563–569 (1992).
  Article CAS Google Scholar
• Wong, G.T., Gannon, K.S. & Margolskee, R.F. Transduction of bitter and sweet taste by gustducin. Nature 381, 796–800 (1996).
  Article CAS Google Scholar
• Huang, L. et al. Gγ13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. Nat. Neurosci. 2, 1055–1062 (1999).
  Article CAS Google Scholar
• Rossler, P. et al. G protein βγ complexes in circumvallate taste cells involved in bitter transduction. Chem. Senses. 25, 413–421 (2000).
  Article CAS Google Scholar
• Rossler, P., Kroner, C., Freitag, J., Noe, J. & Breer, H. Identification of a phospholipase C β subtype in rat taste cells. Eur. J. Cell. Biol. 77, 253–261 (1998).
  Article CAS Google Scholar
• Clapp, T.R., Stone, L.M., Margolskee, R.F. & Kinnamon, S.C. Immunocytochemical evidence for coexpression of Type III IP3 receptor with signaling components of bitter taste transduction. B. M. C. Neurosci. 2, 6 (2001).
  CAS Google Scholar
• Miyoshi, M.A., Abe, K. & Emori, Y. IP3 receptor type 3 and PLCβ2 are coexpressed with taste receptors T1R and T2R in rat taste bud cells. Chem. Senses 26, 259–265 (2001).
  Article CAS Google Scholar
• Misaka, T. et al. Taste buds have a cyclic nucleotide-activated channel, CNGgust. J. Biol. Chem. 272, 22623–22629 (1997).
  Article CAS Google Scholar
• Bernhardt, S.J., Naim, M., Zehavi, U. & Lindemann, B. Changes in IP3 and cytosolic Ca2+ in response to sugars and non-sugar sweeteners in transduction of sweet taste in the rat. J. Physiol. 490, 325–336 (1996).
  Article CAS Google Scholar
• Ogura, T., Mackay-Sim, A. & Kinnamon, S.C. Bitter taste transduction of denatonium in the mudpuppy Necturus maculosus. J. Neurosci. 17, 3580–3587 (1997).
  Article CAS Google Scholar
• Ming, D., Ruiz-Avila, L. & Margolskee, R.F. Characterization and solubilization of bitter-responsive receptors that couple to gustducin. Proc. Natl. Acad. Sci. USA 95, 8933–8938 (1998).
  Article CAS Google Scholar
• Putney, J.W. Jr. & McKay, R.R. Capacitative calcium entry channels. Bioessays 21, 38–46 (1999).
  Article Google Scholar
• Clapham, D.E., Runnels, L.W. & Strubing, C. The trp ion channel family. Nat. Rev. Neurosci. 2, 387–396 (2001).
  Article CAS Google Scholar
• Wong, G.T., Ruiz-Avila, L. & Margolskee, R.F. Directing gene expression to gustducin-positive taste receptor cells. J. Neurosci. 19, 5802–5809 (1999).
  Article CAS Google Scholar
• Yatsuki, H. et al. Sequence-based structural features between Kvlqt1 and Tapa1 on mouse chromosome 7F4/F5 corresponding to the Beckwith-Wiedemann syndrome region on human 11p15.5: long-stretches of unusually well conserved intronic sequences of kvlqt1 between mouse and human. DNA Res. 7, 195–206 (2000).
  Article CAS Google Scholar
• Enklaar, T. et al. Mtr1, a novel biallelically expressed gene in the center of the mouse distal chromosome 7 imprinting cluster, is a member of the Trp gene family. Genomics 67, 179–187 (2000).
  Article CAS Google Scholar
• Prawitt, D. et al. Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression. Hum. Mol. Genet. 9, 203–216 (2000).
  Article CAS Google Scholar
• Montell, C. et al. A unified nomenclature for the superfamily of TRP cation channels. Mol. Cell. 9, 229–231 (2002).
  Article CAS Google Scholar
• Paulsen, M. et al. Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse. Hum. Mol. Genet. 9, 1829–1841 (2000).
  Article CAS Google Scholar
• Gillo, B. et al. Coexpression of Drosophila TRP and TRP-like proteins in Xenopus oocytes reconstitutes capacitative Ca2+ entry. Proc. Natl. Acad. Sci. USA 93, 14146–14151 (1996).
  Article CAS Google Scholar
• Lytton, J., Westlin, M. & Hanley, M.R. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J. Biol. Chem. 266, 17067–17071 (1991).
  CAS PubMed Google Scholar
• Bobanovic, L.K. et al. Molecular cloning and immunolocalization of a novel vertebrate trp homologue from Xenopus. Biochem. J. 340, 593–599 (1999).
  Article CAS Google Scholar
• Halaszovich, C.R., Zitt, C., Jungling, E. & Luckhoff, A. Inhibition of TRP3 channels by lanthanides. Block from the cytosolic side of the plasma membrane. J. Biol. Chem. 275, 37423–37428 (2000).
  Article CAS Google Scholar
• Lomax, R.B., Herrero, C.J., Garcia-Palomero, E., Garcia, A.G. & Montiel, C. Capacitative Ca2+ entry into Xenopus oocytes is sensitive to omega-conotoxins GVIA, MVIIA and MVIIC. Cell Calcium 23, 229–239 (1998).
  Article CAS Google Scholar
• Ogura, T. Acetylcholine increases intracellular Ca2+ in taste cells via activation of muscarinic receptors. J. Neurophysiol. 87, 2643–2649 (2002).
  Article CAS Google Scholar
• Ogura, T., Margolskee, R.F. & Kinnamon, S.C. Taste receptor cell responses to the bitter stimulus denatonium involve Ca2+ influx via store-operated channels. J. Neurophysiol. 87, 3152–3155 (2002).
  Article CAS Google Scholar
• Randriamampita, C. & Tsien, R.Y. Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx. Nature 364, 809–814 (1993).
  Article CAS Google Scholar
• Birnbaumer, L. et al. Mechanism of capacitative Ca2+ entry (CCE): interaction between IP3 receptor and TRP links the internal calcium storage compartment to plasma membrane CCE channels. Recent. Prog. Horm. Res. 55, 127–161 (2000).
  CAS PubMed Google Scholar
• Hofmann, T. et al. Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature 397, 259–263 (1999).
  Article CAS Google Scholar
• Yan, W. et al. Bitter taste transduced by PLC-β(2)-dependent rise in IP3 and alpha-gustducin-dependent fall in cyclic nucleotides. Am. J. Physiol. Cell. Physiol. 280, C742–C751 (2001).
  Article CAS Google Scholar
• Hofmann, T., Schaefer, M., Schultz, G. & Gudermann, T. Subunit composition of mammalian transient receptor potential channels in living cells. Proc. Natl. Acad. Sci. USA 99, 7461–7466 (2002).
  Article CAS Google Scholar
• Hardie, R.C. & Minke, B. The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors. Neuron 8, 643–651 (1992).
  Article CAS Google Scholar
• Liman, E.R., Corey, D.P. & Dulac, C. TRP2: a candidate transduction channel for mammalian pheromone sensory signaling. Proc. Natl. Acad. Sci. USA 96, 5791–5796 (1999).
  Article CAS Google Scholar
• Stortkuhl, K.F., Hovemann, B.T. & Carlson, J.R. Olfactory adaptation depends on the Trp Ca2+ channel in Drosophila. J. Neurosci. 19, 4839–4846 (1999).
  Article CAS Google Scholar
• Liedtke, W. et al. Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell 103, 525–535 (2000).
  Article CAS Google Scholar
• Caterina, M.J. et al. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288, 306–313 (2000).
  Article CAS Google Scholar
• Chan, K.W. et al. A recombinant inwardly rectifying potassium channel coupled to GTP-binding proteins. J. Gen. Physiol. 107, 381–397 (1996).
  Article CAS Google Scholar