- Scales, C. D. Jr., Smith, A. C., Hanley, J. M. & Saigal, C. S. Prevalence of kidney stones in the United States. Eur. Urol. 62, 160–165 (2012).
Article PubMed PubMed Central Google Scholar
- Kirkali, Z., Rasooly, R., Star, R. A. & Rodgers, G. P. Urinary stone disease: progress, status, and needs. Urology 86, 651–653 (2015).
Article PubMed PubMed Central Google Scholar
- Worcester, E. M. & Coe, F. L. Nephrolithiasis. Prim. Care 35, 369–391 (2008).
Article PubMed PubMed Central Google Scholar
- Worcester, E. M. & Coe, F. L. New insights into the pathogenesis of idiopathic hypercalciuria. Semin. Nephrol. 28, 120–132 (2008).
Article CAS PubMed PubMed Central Google Scholar
- Parks, J. H., Worcester, E. M., Coe, F. L., Evan, A. P. & Lingeman, J. E. Clinical implications of abundant calcium phosphate in routinely analyzed kidney stones. Kidney Int. 66, 777–785 (2004).
Article CAS PubMed Google Scholar
- Evan, A. P. et al. Mechanisms of human kidney stone formation. Urolithiasis. 43 (Suppl. 1), 19–32 (2015).
Article PubMed Google Scholar
- Miller, N. L. et al. A formal test of the hypothesis that idiopathic calcium oxalate stones grow on Randall's plaque. BJU Int. 103, 966–971 (2009). This paper provides evidence for the importance of Randall's plaque as the site of attachment of idiopathic calcium oxalate stones.
Article CAS PubMed Google Scholar
- Miller, N. L. et al. In idiopathic calcium oxalate stone-formers, unattached stones show evidence of having originated as attached stones on Randall's plaque. BJU Int. 105, 242–245 (2010).
Article PubMed Google Scholar
- Linnes, M. P. et al. Phenotypic characterization of kidney stone formers by endoscopic and histological quantification of intrarenal calcification. Kidney Int. 84, 818–825 (2013).
Article CAS PubMed PubMed Central Google Scholar
- Wang, X. et al. Distinguishing characteristics of idiopathic calcium oxalate kidney stone formers with low amounts of Randall's plaque. Clin. J. Am. Soc. Nephrol. 9, 1757–1763 (2014).
Article CAS PubMed PubMed Central Google Scholar
- Viers, B. R. et al. Endoscopic and histologic findings in a cohort of uric acid and calcium oxalate stone formers. Urology 85, 771–776 (2015).
Article PubMed PubMed Central Google Scholar
- Letavernier, E. et al. Demographics and characterization of 10,282 Randall plaque-related kidney stones: a new epidemic? Medicine (Baltimore) 94, e566 (2015).
Article Google Scholar
- Evan, A. E. et al. Histopathology and surgical anatomy of patients with primary hyperparathyroidism and calcium phosphate stones. Kidney Int. 74, 223–229 (2008).
Article CAS PubMed Google Scholar
- Evan, A. P. et al. Intra-tubular deposits, urine and stone composition are divergent in patients with ileostomy. Kidney Int. 76, 1081–1088 (2009).
Article CAS PubMed PubMed Central Google Scholar
- Evan, A. P. et al. Renal histopathology and crystal deposits in patients with small bowel resection and calcium oxalate stone disease. Kidney Int. 78, 310–317 (2010).
Article CAS PubMed PubMed Central Google Scholar
- Evan, A. P. et al. Contrasting histopathology and crystal deposits in kidneys of idiopathic stone formers who produce hydroxy apatite, brushite, or calcium oxalate stones. Anat. Rec. (Hoboken) 297, 731–748 (2014).
Article CAS Google Scholar
- Evan, A. P. et al. Crystal-associated nephropathy in patients with brushite nephrolithiasis. Kidney Int. 67, 576–591 (2005).
Article CAS PubMed Google Scholar
- Coe, F. L., Evan, A. P., Lingeman, J. E. & Worcester, E. M. Plaque and deposits in nine human stone diseases. Urol. Res. 38, 239–247 (2010).
Article PubMed PubMed Central Google Scholar
- Evan, A. P. et al. Randall's plaque of patients with nephrolithiasis begins in basement membranes of thin loops of Henle. J. Clin. Invest. 111, 607–616 (2003). Initial description of the papillary anatomy of calcium stone formers and the earliest site of appearance of Randall's plaque.
Article CAS PubMed PubMed Central Google Scholar
- Evan, A. P. et al. Apatite plaque particles in inner medulla of kidneys of calcium oxalate stone formers: osteopontin localization. Kidney Int. 68, 145–154 (2005).
Article CAS PubMed Google Scholar
- Evan, A. P. et al. Renal inter-α-trypsin inhibitor heavy chain 3 increases in calcium oxalate stone-forming patients. Kidney Int. 72, 1503–1511 (2007).
Article CAS PubMed Google Scholar
- Williams, J. C. et al. Micro-CT imaging of Randall's plaques. Urolithiasis 43 (Suppl. 1), 13–17 (2015).
Article PubMed Google Scholar
- Khan, S. R., Rodriguez, D. E., Gower, L. B. & Monga, M. Association of Randall plaque with collagen fibers and membrane vesicles. J. Urol. 187, 1094–1100 (2012).
Article CAS PubMed PubMed Central Google Scholar
- Evan, A. P. et al. Biopsy proven medullary sponge kidney: clinical findings, histopathology, and role of osteogenesis in stone and plaque formation. Anat. Rec. (Hoboken) 298, 865–877 (2015).
Article Google Scholar
- Kuo, R. L. et al. Urine calcium and volume predict coverage of renal papilla by Randall's plaque. Kidney Int. 64, 2150–2154 (2003).
Article PubMed Google Scholar
- Kriz, W. & Kaissling, B. in Structural Organization of the Mammalian Kidney in Seldin and Giebisch's The Kidney: Physiology and Pathophysiology (eds Alpern, R. J. et al.) 595–691 (Elsevier, 2013).
Book Google Scholar
- Bernardo, J. F. & Friedman, P. A. in Renal calcium metabolism in Seldin and Giebisch's The Kidney: Physiology and Pathophysiology (eds Alpern, R. J. et al.) 2225–2247 (Academic Press, 2013).
Book Google Scholar
- Coe, F. L., Evan, A. & Worcester, E. Pathophysiology-based treatment of idiopathic calcium kidney stones. Clin. J. Am. Soc. Nephrol. 6, 2083–2092 (2011).
Article PubMed PubMed Central Google Scholar
- Stoller, M. L., Shami, G. S., McCormick, V. D. & Kerschmann, R. L. High resolution radiography of cadaveric kidneys: unraveling the mystery of Randall's plaque formation. J. Urol. 156, 1263–1266 (1996).
Article CAS PubMed Google Scholar
- Alexander, R. T. et al. Kidney stones and cardiovascular events: a cohort study. Clin. J. Am. Soc. Nephrol. 9, 506–512 (2014).
Article PubMed Google Scholar
- Ferraro, P. M. et al. History of kidney stones and the risk of coronary heart disease. JAMA 310, 408–415 (2013).
Article CAS PubMed PubMed Central Google Scholar
- Evan, A. P. et al. Comparison of the pathology of interstitial plaque in human ICSF stone patients to NHERF-1 and THP-null mice. Urol. Res. 38, 439–452 (2010).
Article CAS PubMed PubMed Central Google Scholar
- Evan, A. P. et al. Mechanism of formation of human calcium oxalate renal stones on Randall's plaque. Anat. Rec. (Hoboken.) 290, 1315–1323 (2007). A description of the ultrastructure of the interface between plaque and the earliest phase of calcium oxalate stone formation.
Article CAS Google Scholar
- Evan, A. P. et al. Renal intratubular crystals and hyaluronan staining occur in stone formers with bypass surgery but not with idiopathic calcium oxalate stones. Anat. Rec. (Hoboken.) 291, 325–334 (2008).
Article Google Scholar
- Evan, A. P. et al. Renal histopathology of stone-forming patients with distal renal tubular acidosis. Kidney Int. 71, 795–801 (2007).
Article CAS PubMed Google Scholar
- Evan, A. P. et al. Renal crystal deposits and histopathology in patients with cystine stones. Kidney Int. 69, 2227–2235 (2006).
Article CAS PubMed Google Scholar
- Worcester, E. M. et al. A test of the hypothesis that oxalate secretion produces proximal tubule crystallization in primary hyperoxaluria type I. Am. J. Physiol. Renal Physiol. 305, F1574–F1584 (2013).
Article CAS PubMed PubMed Central Google Scholar
- Worcester, E. M., Parks, J. H., Evan, A. P. & Coe, F. L. Renal function in patients with nephrolithiasis. J. Urol. 176, 600–603 (2006).
Article PubMed Google Scholar
- Coe, F. L., Evan, A. P., Worcester, E. M. & Lingeman, J. E. Three pathways for human kidney stone formation. Urol. Res. 38, 147–160 (2010).
Article PubMed PubMed Central Google Scholar
- Rule, A. D., Krambeck, A. E. & Lieske, J. C. Chronic kidney disease in kidney stone formers. Clin. J. Am. Soc. Nephrol. 6, 2069–2075 (2011).
Article PubMed PubMed Central Google Scholar
- Coe, F. L. & Parks, J. H. in Physical Chemistry of Calcium Stone Disease in Nephrolithiasis: Pathogenesis and Treatment (eds Coe, F. L. & Parks, J. H.) 38–58 (Year Book Medical Publishers, 1988).
Google Scholar
- Qiu, S. R. & Orme, C. A. Dynamics of biomineral formation at the near-molecular level. Chem. Rev. 108, 4784–4822 (2008).
Article CAS PubMed Google Scholar
- Finlayson, B. in Calcium stones: some physical and clinical aspects in Calcium metabolism in renal failure and nephrolithiasis (eds David, D. S.) 337–382 (John Wiley & Sons, 1977). A description of the method for computation of urinary supersaturation in stone formers.
Google Scholar
- Parks, J. H., Coward, W. M. & Coe, F. L. Correspondence between stone composition and urine supersaturation in nephrolithiasis. Kidney Int. 51, 894–900 (1997).
Article CAS PubMed Google Scholar
- Bergsland, K. J., Zisman, A. L., Asplin, J. R., Worcester, E. M. & Coe, F. L. Evidence for net renal tubule oxalate secretion in patients with calcium kidney stones. Am. J. Physiol. Renal Physiol. 300, F311–F318 (2011).
Article CAS PubMed Google Scholar
- Santucci, L. et al. Urinary proteome in a snapshot: normal urine and glomerulonephritis. J. Nephrol. 26, 610–616 (2013).
Article CAS PubMed Google Scholar
- Wright, C. A. et al. Label-free quantitative proteomics reveals differentially regulated proteins influencing urolithiasis. Mol. Cell. Proteomics 10, M110 (2011).
Article CAS PubMed PubMed Central Google Scholar
- Kumar, V. & Lieske, J. C. Protein regulation of intrarenal crystallization. Curr. Opin. Nephrol. Hypertens. 15, 374–380 (2006). A review of the role of urinary crystallization inhibitors in preventing kidney stones.
Article CAS PubMed Google Scholar
- Aggarwal, K. P., Narula, S., Kakkar, M. & Tandon, C. Nephrolithiasis: molecular mechanism of renal stone formation and the critical role played by modulators. Biomed. Res. Int. 2013, 292953 (2013).
Article CAS PubMed PubMed Central Google Scholar
- Canales, B. K. et al. Proteome of human calcium kidney stones. Urology 76, 1017–1020 (2010).
Article PubMed Google Scholar
- Pak, C. Y. C. Physicochemical basis for formation of renal stones of calcium phosphate origin: calculation of the degree of supersaturation of urine with respect to brushite. J. Clin. Invest. 48, 1914–1922 (1969). A fundamental explanation of urinary supersaturation with respect to calcium phosphate.
Article CAS PubMed PubMed Central Google Scholar
- Nancollas, G. H. & Henneman, Z. J. Calcium oxalate: calcium phosphate transformations. Urol. Res. 38, 277–280 (2010).
Article CAS PubMed Google Scholar
- Costa-Bauza, A. et al. Type of renal calculi: variation with age and sex. World J. Urol. 25, 415–421 (2007).
Article PubMed Google Scholar
- Joseph, N. R. The dissociation constants of organic calcium complexes. J. Biol. Chem. 164, 529–541 (1946).
CAS PubMed Google Scholar
- Rodgers, A. L., Allie-Hamdulay, S., Jackson, G. E. & Sutton, R. A. Enteric hyperoxaluria secondary to small bowel resection: use of computer simulation to characterize urinary risk factors for stone formation and assess potential treatment protocols. J. Endourol. 28, 985–994 (2014).
Article PubMed Google Scholar
- De Yoreo, J. J., Qiu, S. R. & Hoyer, J. R. Molecular modulation of calcium oxalate crystallization. Am. J. Physiol. Renal Physiol. 291, F1123–F1131 (2006).
Article CAS PubMed Google Scholar
- Coe, F. L., Parks, J. H. & Moore, E. S. Familial idiopathic hypercalciuria. N. Engl. J. Med. 300, 337–340 (1979).
Article CAS PubMed Google Scholar
- Albright, F., Henneman, P., Benedict, P. H. & Forbes, A. P. Idiopathic hypercalciuria: a preliminary report. Proc. R. Soc. Med. 46, 1077–1081 (1953).
CAS PubMed PubMed Central Google Scholar
- Heilberg, I. P. & Weisinger, J. R. Bone disease in idiopathic hypercalciuria. Curr. Opin. Nephrol. Hypertens. 15, 394–402 (2006). An excellent review of the nature of the bone disease in patients with idiopathic hypercalciuria.
Article CAS PubMed Google Scholar
- Curhan, G. C. & Taylor, E. N. 24-h uric acid excretion and the risk of kidney stones. Kidney Int. 73, 489–496 (2008). A presentation of data from a large prospective observational study that sheds light on urinary risk factors for stone formation.
Article CAS PubMed Google Scholar
- Blaine, J., Chonchol, M. & Levi, M. Renal control of calcium, phosphate, and magnesium homeostasis. Clin. J. Am. Soc. Nephrol. 10, 1257–1272 (2015).
Article CAS PubMed Google Scholar
- Liberman, U. A. et al. Metabolic and calcium kinetic studies in idiopathic hypercalciuria. J. Clin. Invest. 47, 2580–2590 (1968).
Article CAS PubMed PubMed Central Google Scholar
- Heaney, R. P. & Skillman, T. G. Secretion and excretion of calcium by the human gastrointestinal tract. J. Lab. Clin. Med. 64, 29–41 (1964).
CAS PubMed Google Scholar
- Nassim, J. R. & Higgins, B. A. Control of idiopathic hypercalciuria. Br. Med. J. 1, 675–681 (1965).
Article CAS PubMed PubMed Central Google Scholar
- Edwards, N. A. & Hodgekinson, A. Metabolic studies in patients with idiopathic hypercalciuria. Clin. Sci. 29, 143–157 (1965).
CAS PubMed Google Scholar
- Henneman, P. H., Benedict, P. H., Forbes, A. P. & Dudley, H. R. Idiopathic hypercalciuria. N. Engl. J. Med. 259, 802–807 (1958).
Article CAS PubMed Google Scholar
- Jackson, W. P. U. & Dancaster, C. A consideration of the hypercalciuria in sarcoidosis, idiopathic hypercalciuria, and that produced by vitamin D. A new suggestion regarding calcium metabolism. J. Clin. Endocrinol. Metab. 19, 658 (1959).
Article CAS PubMed Google Scholar
- Harrison, A. R. Some results of metabolic investigations in cases of renal stone. Br. J. Urol. 31, 398 (1959).
Article CAS PubMed Google Scholar
- Dent, C. E., Harper, C. M. & Parfitt, A. M. The effect of cellulose phosphate on calcium metabolism in patients with hypercalciuria. Clin. Sci. 27, 417–425 (1964).
CAS PubMed Google Scholar
- Parfitt, A. M., Higgins, B. A., Nassim, J. R., Collins, J. A. & Hilb, A. Metabolic studies in patients with hypercalciuria. Clin. Sci. 27, 463–482 (1964).
CAS PubMed Google Scholar
- Yendt, E. R., Gagne, R. J. A. & Cohanim, M. The effects of thiazides in idiopathic hypercalciuria. Trans. Am. Clin. Climatol. Assoc. 77, 96–110 (1966).
CAS PubMed PubMed Central Google Scholar
- Dent, C. E. & Watson, L. Metabolic studies in a patient with idiopathic hypercalciuria. Br. Med. J. 2, 449–452 (1965).
Article CAS PubMed PubMed Central Google Scholar
- Anderson, J., Lee, H. A. & Tomlinson, R. W. Some metabolic aspects of idiopathic hypercalciuria. Nephron 4, 129–138 (1967).
Article CAS PubMed Google Scholar
- Khanal, R. C. & Nemere, I. Regulation of intestinal calcium transport. Annu. Rev. Nutr. 28, 179–196 (2008).
Article CAS PubMed Google Scholar
- Insogna, K. L., Broadus, A. E., Dreyer, B. E., Ellison, A. F. & Gertner, J. M. Elevated production rate of 1,25-dihydroxyvitamin D in patients with absorptive hypercalciuria. J. Clin. Endocrinol. Metab. 61, 490–495 (1985).
Article CAS PubMed Google Scholar
- Bushinsky, D. A., Frick, K. K. & Nehrke, K. Genetic hypercalciuric stone-forming rats. Curr. Opin. Nephrol. Hypertens. 15, 403–418 (2006).
Article CAS PubMed Google Scholar
- Worcester, E. M. et al. Evidence that postprandial reduction of renal calcium reabsorption mediates hypercalciuria of patients with calcium nephrolithiasis. Am. J. Physiol. Renal Physiol. 292, F66–F75 (2007).
Article CAS PubMed Google Scholar
- Worcester, E. M., Bergsland, K. J., Gillen, D. L. & Coe, F. L. Evidence for increased renal tubule and parathyroid gland sensitivity to serum calcium in human idiopathic hypercalciuria. Am. J. Physiol. Renal Physiol. 305, F853–F860 (2013).
Article CAS PubMed PubMed Central Google Scholar
- Worcester, E. M. et al. Evidence for increased postprandial distal nephron calcium delivery in hypercalciuric stone-forming patients. Am. J. Physiol. Renal Physiol. 295, F1286–F1294 (2008). This paper provides evidence that proximal tubule sodium and calcium reabsorption is lower in patients with idiopathic hypercalciuria than in normal individuals, and that this difference contributes to elevated urine calcium excretion.
Article CAS PubMed PubMed Central Google Scholar
- Coe, F. L. et al. Effects of low-calcium diet on urine calcium excretion, parathyroid function and serum 1,25(OH)2D3 levels in patients with idiopathic hypercalciuria and in normal subjects. Am. J. Med. 72, 25–32 (1982). An important study showing that altered renal calcium reabsorption is a key feature of idiopathic hypercalciuria.
Article CAS PubMed Google Scholar
- Qaseem, A., Dallas, P., Forciea, M. A., Starkey, M. & Denberg, T. D. Dietary and pharmacologic management to prevent recurrent nephrolithiasis in adults: a clinical practice guideline from the American College of Physicians. Ann. Intern. Med. 161, 659–667 (2014).
Article PubMed Google Scholar
- Bergsland, K. J., Coe, F. L., Gillen, D. L. & Worcester, E. M. A test of the hypothesis that the collecting duct calcium-sensing receptor limits rise of urine calcium molarity in hypercalciuric calcium kidney stone formers. Am. J. Physiol. Renal Physiol. 297, F1017–F1023 (2009).
Article CAS PubMed PubMed Central Google Scholar
- Pak, C. Y. C., Sakhaee, K., Crowther, C. & Brinkley, L. Evidence justifying a high fluid intake in treatment of nephrolithiaisis. Ann. Intern. Med. 93, 36–39 (1980).
Article CAS PubMed Google Scholar
- Borghi, L. et al. Urinary volume, water and recurrences of idiopathic calcium nephrolithiasis: a 5-year randomized prospective study. J. Urol. 155, 839–843 (1996). Evidence for the importance of fluid intake as a way to prevent recurrence of calcium stones.
Article CAS PubMed Google Scholar
- Breslau, N. A., Mcguire, J. L., Zerwekh, J. E. & Pak, C. Y. C. The role of dietary sodium on renal excretion and intstinal absorption of calicum and on vitamin D metabolism. J. Clin. Endocrinol. Metab. 55, 369–373 (1982).
Article CAS PubMed Google Scholar
- Sakhaee, K., Harvey, J. A., Padalino, P., Whitson, P. & Pak, C. Y. C. The potential role of salt abuse on the risk for kidney stone formation. J. Urol. 150, 310–312 (1993).
Article CAS PubMed Google Scholar
- McCarron, D. A. et al. Urinary calcium excretion at extremes of sodium intake in normal man. Am. J. Nephrol. 1, 84–90 (1981).
Article CAS PubMed Google Scholar
- Phillips, M. J. & Cooke, J. N. C. Relation between urinary calcium and sodium in patients with idiopathic hypercalciuria. Lancet 1, 1354–1357 (1967).
Article CAS PubMed Google Scholar
- Teucher, B. et al. Sodium and bone health: impact of moderately high and low salt intakes on calcium metabolism in postmenopausal women. J. Bone Miner. Res. 23, 1477–1485 (2008).
Article CAS PubMed Google Scholar
- McParland, B. E., Goulding, A. & Campbell, A. J. Dietary salt affects biochemical markers of resorption and formation of bone in elderly women. BMJ 299, 834–835 (1989).
Article CAS PubMed PubMed Central Google Scholar
- Frings-Meuthen, P., Baecker, N. & Heer, M. Low-grade metabolic acidosis may be the cause of sodium chloride-induced exaggerated bone resorption. J. Bone Miner. Res. 23, 517–524 (2008).
Article CAS PubMed Google Scholar
- Nascimento, L., Oliveros, F. H. & Cunningham, E. Renal handling of sodium and calcium in hypercalciuria. Clin. Pharmacol. Ther. 35, 342–347 (1984).
Article CAS PubMed Google Scholar
- Pak, C. Y. et al. Effect of dietary modification on urinary stone risk factors. Kidney Int. 68, 2264–2273 (2005).
Article CAS PubMed Google Scholar
- Muldowney, F. P., Freaney, R. & K.Moloney, M. F. Importance of dietary sodium in the hypercalciuria syndrome. Kidney Int. 22, 292–296 (1982).
Article CAS PubMed Google Scholar
- Silver, J., Rubinger, D., Friedlaender, M. M. & Popovtzer, M. M. Sodium-dependent idiopathic hypercalciuria in renal-stone formers. Lancet 2, 484–486 (1983).
Article CAS PubMed Google Scholar
- Nouvenne, A. et al. Diet to reduce mild hyperoxaluria in patients with idiopathic calcium oxalate stone formation: a pilot study. Urology 73, 725–730. e1 (2009).
Article PubMed Google Scholar
- Nouvenne, A. et al. Effects of a low-salt diet on idiopathic hypercalciuria in calcium-oxalate stone formers: a 3-mo randomized controlled trial. Am. J. Clin. Nutr. 91, 565–570 (2010).
Article CAS PubMed Google Scholar
- Burtis, W. J., Gay, L., Insogna, K. L., Ellison, A. & Broadus, A. E. Dietary hypercalciuria in patients with calcium oxalate kidney stones. Am. J. Clin. Nutr. 60, 424–429 (1994).
Article CAS PubMed Google Scholar
- Blackwood, A. M., Sagnella, G. A., Cook, D. G. & Cappuccio, F. P. Urinary calcium excretion, sodium intake and blood pressure in a multi-ethnic population: results of the Wandsworth Heart and Stroke Study. J. Hum. Hypertens. 15, 229–237 (2001).
Article CAS PubMed Google Scholar
- Taylor, E. N. & Curhan, G. C. Demographic, dietary, and urinary factors and 24-h urinary calcium excretion. Clin. J. Am. Soc. Nephrol. 4, 1980–1987 (2009).
Article CAS PubMed PubMed Central Google Scholar
- Damasio, P. C. et al. The role of salt abuse on risk for hypercalciuria. Nutr. J. 10, 3 (2011).
Article CAS PubMed PubMed Central Google Scholar
- Borghi, L. et al. Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N. Engl. J. Med. 346, 77–84 (2002). This study documents the efficacy of a low sodium, normal calcium, moderately low protein diet to prevent recurrent calcium oxalate stones.
Article CAS PubMed Google Scholar
- U.S. Department of Agriculture & U.S. Department of Health and Human Services. Dietary Guidelines for Americans (U.S. Government Printing Office, 2010).
- Yendt, E. R., Gagne, R. J. A. & Cohanim, M. The effects of thiazides in idiopathic hypercalciuria. Am. J. Med. Sci. 261, 449–460 (1966).
Article Google Scholar
- Fink, H. A. et al. Medical management to prevent recurrent nephrolithiasis in adults: a systematic review for an American College of Physicians Clinical Guideline. Ann. Intern. Med. 158, 535–543 (2013).
Article PubMed Google Scholar
- Laerum, E. & Larsen, S. Thiazide prophylaxis of urolithiasis: a double-blind study in general practice. Acta Med. Scand. 215, 383–389 (1984).
Article CAS PubMed Google Scholar
- Ettinger, B., Citron, J. T., Livermore, B. & Dolman, L. I. Chlorthalidone reduces calcium oxalate calculous recurrence but magnesium hydroxide does not. J. Urol. 139, 679–684 (1988).
Article CAS PubMed Google Scholar
- Borghi, L., Meschi, T., Guerra, A. & Novarini, A. Randomized prospective study of a nonthiazide diuretic, indapamide, in preventing calcium stone recurrences. J. Cardiovasc. Pharmacol. 22, S78–S86 (1993).
Article PubMed Google Scholar
- Bergsland, K. J., Worcester, E. M. & Coe, F. L. Role of proximal tubule in the hypocalciuric response to thiazide of patients with idiopathic hypercalciuria. Am. J. Physiol. Renal Physiol. 305, F592–F599 (2013).
Article CAS PubMed PubMed Central Google Scholar
- Coe, F. L., Parks, J. H., Bushinsky, D. A., Langman, C. B. & Favus, M. J. Chlorthalidone promotes mineral retention in patients with idiopathic hypercalciuria. Kidney Int. 33, 1140–1146 (1988).
Article CAS PubMed Google Scholar
- Bolland, M. J. et al. The effect of treatment with a thiazide diuretic for 4 years on bone density in normal postmenopausal women. Osteoporos. Int. 18, 479–486 (2007).
Article CAS PubMed Google Scholar
- Aung, K. & Htay, T. Thiazide diuretics and the risk of hip fracture. Cochrane Database Syst. Rev. 10, CD005185 (2011).
Google Scholar
- Caudarella, R., Vescini, F., Buffa, A. & Stefoni, S. Citrate and mineral metabolism: kidney stones and bone disease. Front. Biosci. 8, s1084–s1106 (2003).
Article PubMed Google Scholar
- Curthoys, N. P. & Moe, O. W. Proximal tubule function and response to acidosis. Clin. J. Am. Soc. Nephrol. 9, 1627–1638 (2014).
Article CAS PubMed Google Scholar
- Halperin, M. L., Cheema, D. S. & Kamel, K. S. Physiology of acid-base balance: links with kidney stone prevention. Semin. Nephrol. 26, 441–446 (2006).
Article CAS PubMed Google Scholar
- Pinheiro, V. B., Baxmann, A. C., Tiselius, H. G. & Heilberg, I. P. The effect of sodium bicarbonate upon urinary citrate excretion in calcium stone formers. Urology 82, 33–37 (2013).
Article PubMed Google Scholar
- Moseley, K. F., Weaver, C. M., Appel, L., Sebastian, A. & Sellmeyer, D. E. Potassium citrate supplementation results in sustained improvement in calcium balance in older men and women. J. Bone Miner. Res. 28, 497–504 (2013).
Article CAS PubMed PubMed Central Google Scholar
- Menegon, L. F., Figueiredo, J. F. & Gontijo, J. A. Effect of metabolic acidosis on renal tubular sodium handling in rats as determined by lithium clearance. Braz. J. Med. Biol. Res. 31, 1269–1273 (1998).
Article CAS PubMed Google Scholar
- Safirstein, R., Glassman, V. P. & DiScala, V. A. Effects of an NH4Cl-induced metabolic acidosis on salt and water reabsorption in dog kidney. Am. J. Physiol. 225, 805–809 (1973).
Article CAS PubMed Google Scholar
- Wang, T., Egbert, A. L. Jr., Aronson, P. S. & Giebisch, G. Effect of metabolic acidosis on NaCl transport in the proximal tubule. Am. J. Physiol. 274, F1015–F1019 (1998).
CAS PubMed Google Scholar
- Balkovetz, D. F., Chumley, P. & Amlal, H. Downregulation of claudin-2 expression in renal epithelial cells by metabolic acidosis. Am. J. Physiol. Renal Physiol. 297, F604–F611 (2009).
Article CAS PubMed Google Scholar
- Barcelo, P., Wuhl, O., Servitge, E., Rousaud, A. & Pak, C. Y. C. Randomized double-blind study of potassium citrate in idiopathic hypocitraturic calcium nephrolithiasis. J. Urol. 150, 1761–1764 (1993).
Article CAS PubMed Google Scholar
- Ettinger, B. et al. Potassium-magnesium citrate is an effective prophylaxis against recurrent calcium oxalate nephrolithiasis. J. Urol. 158, 2069–2073 (1997).
Article CAS PubMed Google Scholar
- Hofbauer, J., Hobarth, K., Szabo, N. & Marberger, M. Alkali citrate prophylaxis in idiopathic recurrent calcium oxalate urolithiasis — a prospective randomized study. Br. J. Urol. 73, 362–365 (1994).
Article CAS PubMed Google Scholar
- Soygur, T., Akbay, A. & Kupeli, S. Effect of potassium citrate therapy on stone recurrence and residual fragments after shockwave lithotripsy in lower caliceal calcium oxalate urolithiasis: a randomized controlled trial. J. Endourol. 16, 149–152 (2002).
Article PubMed Google Scholar
- Lojanapiwat, B. et al. Alkaline citrate reduces stone recurrence and regrowth after shockwave lithotripsy and percutaneous nephrolithotomy. Int. Braz. J. Urol. 37, 611–616 (2011).
Article CAS PubMed Google Scholar
- Johnsson, M. S. & Nancollas, G. H. The role of brushite and octacalcium phosphate in apatite formation. Crit. Rev. Oral Biol. Med. 3, 61–82 (1992).
Article CAS PubMed Google Scholar