The active site of the SET domain is constructed on a knot (original ) (raw ) References
Jenuwein, T. Trends Cell Biol. 11 , 266–273 (2001).Article CAS Google Scholar
Zhang, Y. & Reinberg, D. Genes Dev. 15 , 2343–2360 (2001).Article CAS Google Scholar
Jenuwein, T. & Allis, C.D. Science 293 , 1074–1080 (2001).Article CAS Google Scholar
Rea, S. et al. Nature 406 , 593–599 (2000).Article CAS Google Scholar
Strahl, B.D., Ohba, R., Cook, R.G. & Allis, C.D. Proc. Natl. Acad. Sci. USA 96 , 14967–14972 (1999).Article CAS Google Scholar
Wang, H. et al. Mol. Cell 8 , 1207–1217 (2001).Article CAS Google Scholar
Nishioka, K. et al. Genes Dev. 16 , 479–489 (2002).Article CAS Google Scholar
Fauman, E.B., Blumenthal, R.M. & Cheng, X. Structure and Evolution of AdoMet-dependent Methyltransferases (eds Cheng, X. & Blumenthal, R.M.) 1–38 (World Scientific, Singapore; 1999).Book Google Scholar
Fang, J. et al. Curr. Biol. 12 , 1086–1099 (2002).Article CAS Google Scholar
Nishioka, K. et al. Mol. Cell 9 , 1201–1213 (2002).Article CAS Google Scholar
Strahl, B.D. et al. Mol. Cell Biol. 22 , 1298–1306 (2002).Article CAS Google Scholar
Lachner, M. & Jenuwein, T. Curr. Opin. Cell Biol. 14 , 286–298 (2002).Article CAS Google Scholar
Zhang, X., Zhou, L. & Cheng, X. EMBO J. 19 , 3509–3519 (2000).Article CAS Google Scholar
Cheng, X. & Roberts, R.J. Nucleic Acids Res. 29 , 3784–3795 (2001).Article CAS Google Scholar
Sun, P.D. & Davies, D.R. Annu. Rev. Biophys. Biomol. Struct. 24 , 269–291 (1995).Article CAS Google Scholar
Nureki, O. et al. Acta Crystallogr. D 58 , 1129–1137 (2002).Article Google Scholar
Jacobs, S.A. et al. EMBO J. 20 , 5232–5241 (2001).Article CAS Google Scholar
Jacobs, S.A. & Khorasanizadeh, S. Science 295 , 2080–2083 (2002).Article CAS Google Scholar
Luger, K., Maeder, A.W., Richmond, R.K., Sargent, D.F. & Richmond, T.J. Nature 389 , 251–259 (1997).Article CAS Google Scholar
Harp, J.M., Hanson, B.L., Timm, D.E. & Bunick, G.J. Acta Crystallogr. D 56 , 1513–1534 (2000).Article CAS Google Scholar
Coward, J.K. in The Biochemistry of Adenosylmethionine (eds Salvatore, F., Borek, E., Zappia, V., William-Ashman, H.G. & Schlenk, F.) 127–144 (Columbia University Press, New York; 1977). Google Scholar
Komoto, J. et al. J. Mol. Biol. 320 , 223–235 (2002).Article CAS Google Scholar
Ramakrishnan, V., Finch, J.T., Graziano, V., Lee, P.L. & Sweet, R.M. Nature 362 , 219–223 (1993).Article CAS Google Scholar
Grzesiek, S. & Bax, A. J. Am. Chem. Soc. 115 , 12593–12593 (1993).Article CAS Google Scholar
Delaglio, F. et al. J. Biomol. NMR 6 , 277–293 (1995).Article CAS Google Scholar
Johnson, B.A. & Blevins, R.A. J. Biomol. NMR 4 , 603–614 (1994).Article CAS Google Scholar
Otwinowski, Z. & Minor, W. Methods. Enzymol. 276 , 307–326 (1997).Article CAS Google Scholar
Terwilliger, T.C. & Berendzen, J. Acta Crystallogr. D 55 , 849–861 (1999).Article CAS Google Scholar
Cowtan, K. Acta Crystallogr. D 50 , 760–763 (1994).Article Google Scholar
Perrakis, A., Morris, R.J. & Lamzin, V.S. Nature Struct. Biol. 6 , 458–468 (1999).Article CAS Google Scholar
Brunger, A.T. et al. Acta Crystallogr. D 54 , 905–921 (1998).Article CAS Google Scholar
Jones, T.A. & Kjeldgaard, M. O version 5.9 (Uppsala University, Uppsala; 1994). Google Scholar
McRee, D.E. J. Struct. Biol. 125 , 156–165 (1999).Article CAS Google Scholar
Carson, M. J. Appl. Crystallogr. 24 , 958–961 (1991).Article Google Scholar
Wallace, A.C., Laskowski, R.A. & Thornton, J.M. Protein Eng. 8 , 127–134 (1995).Article CAS Google Scholar
Nicholls, A., Sharp, K.A. & Honig, B. Proteins 11 , 281–296 (1991).Article CAS Google Scholar
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