- Goodenough, U.W. & Heuser, J. Substructure of inner dynein arms, radial spokes, and the central pair/projection complex of cilia and flagella. J. Cell Biol. 100, 2008–2018 (1985).
Article CAS PubMed Google Scholar
- Piperno, G., Ramanis, Z., Smith, E.F. & Sale, W.S. Three distinct inner dynein arms in Chlamydomonas flagella: molecular composition and location in the axoneme. J. Cell Biol. 110, 379–389 (1990).
Article CAS PubMed Google Scholar
- Porter, M.E. Axonemal dyneins: assembly, organization, and regulation. Curr. Opin. Cell Biol. 8, 10–17 (1996).
Article CAS PubMed Google Scholar
- Kamiya, R. Functional diversity of axonemal dyneins as studied in Chlamydomonas mutants. Int. Rev. Cytol. 219, 115–155 (2002).
Article CAS PubMed Google Scholar
- Bui, K.H., Sakakibara, H., Movassagh, T., Oiwa, K. & Ishikawa, T. Molecular architecture of inner dynein arms in situ in Chlamydomonas reinhardtii flagella. J. Cell Biol. 183, 923–932 (2008).
Article CAS PubMed PubMed Central Google Scholar
- Fliegauf, M. et al. Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia. Am. J. Respir. Crit. Care Med. 171, 1343–1349 (2005).
Article PubMed PubMed Central Google Scholar
- Neuwald, A.F., Aravind, L., Spouge, J.L. & Koonin, E.V. AAA+: a class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes. Genome Res. 9, 27–43 (1999).
CAS PubMed Google Scholar
- Johnson, K.A. Pathway of the microtubule-dynein ATPase and the structure of dynein: a comparison with actomyosin. Annu. Rev. Biophys. Biophys. Chem. 14, 161–188 (1985).
Article CAS PubMed Google Scholar
- Burgess, S.A., Walker, M.L., Sakakibara, H., Knight, P.J. & Oiwa, K. Dynein structure and power stroke. Nature 421, 715–718 (2003).
Article CAS PubMed Google Scholar
- Ishikawa, T., Sakakibara, H. & Oiwa, K. The architecture of outer dynein arms in situ. J. Mol. Biol. 368, 1249–1258 (2007).
Article CAS PubMed Google Scholar
- Lupetti, P. et al. Three-dimensional reconstruction of axonemal outer dynein arms in situ by electron tomography. Cell Motil. Cytoskeleton 62, 69–83 (2005).
Article PubMed Google Scholar
- Nicastro, D. et al. The molecular architecture of axonemes revealed by cryoelectron tomography. Science 313, 944–948 (2006).
Article CAS PubMed Google Scholar
- Porter, M.E., Knott, J.A., Myster, S.H. & Farlow, S.J. The dynein gene family in Chlamydomonas reinhardtii. Genetics 144, 569–585 (1996).
CAS PubMed PubMed Central Google Scholar
- Ueno, H., Yasunaga, T., Shingyoji, C. & Hirose, K. Dynein pulls microtubules without rotating its stalk. Proc. Natl. Acad. Sci. USA 105, 19702–19707 (2008).
Article CAS PubMed PubMed Central Google Scholar
- Burgess, S.A., Walker, M.L., Sakakibara, H., Oiwa, K. & Knight, P.J. The structure of dynein-c by negative stain electron microscopy. J. Struct. Biol. 146, 205–216 (2004).
Article CAS PubMed Google Scholar
- Carter, A.P. et al. Structure and functional role of dynein′s microtubule-binding domain. Science 322, 1691–1695 (2008).
Article CAS PubMed PubMed Central Google Scholar
- Gibbons, B.H. & Gibbons, I.R. Properties of flagellar “rigor waves” formed by abrupt removal of adenosine triphosphate from actively swimming sea urchin sperm. J. Cell Biol. 63, 970–985 (1974).
Article CAS PubMed PubMed Central Google Scholar
- Bui, K.H., Sakakibara, H., Movassagh, T., Oiwa, K. & Ishikawa, T. Asymmetry of inner dynein arms and inter-doublet links in Chlamydomonas flagella. J. Cell Biol. 186, 437–446 (2009).
Article CAS PubMed PubMed Central Google Scholar
- Roberts, A.J. et al. AAA+ ring and linker swing mechanism in the dynein motor. Cell 136, 485–495 (2009).
Article CAS PubMed PubMed Central Google Scholar
- Gibbons, I.R. Dynein family of motor proteins: present status and future questions. Cell Motil. Cytoskeleton 32, 136–144 (1995).
Article CAS PubMed Google Scholar
- Sakato, M., Sakakibara, H. & King, S.M. Chlamydomonas outer arm dynein alters conformation in response to Ca2+. Mol. Biol. Cell 18, 3620–3634 (2007).
Article CAS PubMed PubMed Central Google Scholar
- Furuta, A., Yagi, T., Yanagisawa, H.A., Higuchi, H. & Kamiya, R. Systematic comparison of in vitro motile properties between Chlamydomonas wild-type and mutant outer arm dyneins each lacking one of the three heavy chains. J. Biol. Chem. 284, 5927–5935 (2009).
Article CAS PubMed Google Scholar
- Goodenough, U.W. & Heuser, J.E. Substructure of the outer dynein arm. J. Cell Biol. 95, 798–815 (1982).
Article CAS PubMed Google Scholar
- Kon, T., Mogami, T., Ohkura, R., Nishiura, M. & Sutoh, K. ATP hydrolysis cycle-dependent tail motions in cytoplasmic dynein. Nat. Struct. Mol. Biol. 12, 513–519 (2005).
Article CAS PubMed Google Scholar
- Hook, P. et al. Long range allosteric control of cytoplasmic dynein ATPase activity by the stalk and C-terminal domains. J. Biol. Chem. 280, 33045–33054 (2005).
Article PubMed Google Scholar
- Inoue, Y. & Shingyoji, C. The roles of noncatalytic ATP binding and ADP binding in the regulation of dynein motile activity in flagella. Cell Motil. Cytoskeleton 64, 690–704 (2007).
Article CAS PubMed Google Scholar
- Takahashi, Y., Edamatsu, M. & Toyoshima, Y.Y. Multiple ATP-hydrolyzing sites that potentially function in cytoplasmic dynein. Proc. Natl. Acad. Sci. USA 101, 12865–12869 (2004).
Article CAS PubMed PubMed Central Google Scholar
- Holzbaur, E.L. & Johnson, K.A. ADP release is rate limiting in steady-state turnover by the dynein adenosinetriphosphatase. Biochemistry 28, 5577–5585 (1989).
Article CAS PubMed Google Scholar
- Holzbaur, E.L. & Johnson, K.A. Microtubules accelerate ADP release by dynein. Biochemistry 28, 7010–7016 (1989).
Article CAS PubMed Google Scholar
- Warner, F.D. & McIlvain, J.H. Kinetic properties of microtubule-activated 13 S and 21 S dynein ATPases. Evidence for allosteric behaviour associated with the inner row and outer row dynein arms. J. Cell Sci. 83, 251–267 (1986).
CAS PubMed Google Scholar
- Seetharam, R.N. & Satir, P. Coordination of outer arm dynein activity along axonemal doublet microtubules. Cell Motil. Cytoskeleton 65, 572–580 (2008).
Article CAS PubMed Google Scholar
- Haimo, L.T. & Rosenbaum, J.L. Dynein binding to microtubules containing microtubule-associated proteins. Cell Motil. 1, 499–515 (1981).
Article CAS PubMed Google Scholar
- Moss, A.G., Sale, W.S., Fox, L.A. & Witman, G.B. The alpha subunit of sea urchin sperm outer arm dynein mediates structural and rigor binding to microtubules. J. Cell Biol. 118, 1189–1200 (1992).
Article CAS PubMed Google Scholar
- Burgess, S.A. Rigor and relaxed outer dynein arms in replicas of cryofixed motile flagella. J. Mol. Biol. 250, 52–63 (1995).
Article CAS PubMed Google Scholar
- Mallik, R., Carter, B.C., Lex, S.A., King, S.J. & Gross, S.P. Cytoplasmic dynein functions as a gear in response to load. Nature 427, 649–652 (2004).
Article CAS PubMed Google Scholar
- Ishikawa, R. & Shingyoji, C. Induction of beating by imposed bending or mechanical pulse in demembranated, motionless sea urchin sperm flagella at very low ATP concentrations. Cell Struct. Funct. 32, 17–27 (2007).
Article CAS PubMed Google Scholar
- Gorman, D.S. & Levine, R.P. Cytochrome f and plastocyanin: their sequence in the photosynthetic electron transport chain of Chlamydomonas reinhardtii. Proc. Natl. Acad. Sci. USA 54, 1665–1669 (1965).
Article CAS PubMed PubMed Central Google Scholar
- Witman, G.B. Isolation of Chlamydomonas flagella and flagellar axonemes. Methods Enzymol. 134, 280–290 (1986).
Article CAS PubMed Google Scholar
- Striebel, F. et al. Bacterial ubiquitin-like modifier Pup is deamidated and conjugated to substrates by distinct but homologous enzymes. Nat. Struct. Mol. Biol. 16, 647–651 (2009).
Article CAS PubMed Google Scholar
- Kremer, J.R., Mastronarde, D.N. & McIntosh, J.R. Computer visualization of three-dimensional image data using IMOD. J. Struct. Biol. 116, 71–76 (1996).
Article CAS PubMed Google Scholar
- Mastronarde, D.N. Dual-axis tomography: an approach with alignment methods that preserve resolution. J. Struct. Biol. 120, 343–352 (1997).
Article CAS PubMed Google Scholar
- Heymann, J.B. Bsoft: image and molecular processing in electron microscopy. J. Struct. Biol. 133, 156–169 (2001).
Article CAS PubMed Google Scholar
- Frank, J. et al. SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J. Struct. Biol. 116, 190–199 (1996).
Article CAS PubMed Google Scholar
- Nickell, S. et al. TOM software toolbox: acquisition and analysis for electron tomography. J. Struct. Biol. 149, 227–234 (2005).
Article PubMed Google Scholar
- Bostina, M. et al. Single particle cryoelectron tomography characterization of the structure and structural variability of poliovirus-receptor-membrane complex at 30 Å resolution. J. Struct. Biol. 160, 200–210 (2007).
Article CAS PubMed PubMed Central Google Scholar
- Pettersen, E.F. et al. UCSF Chimera - a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605–1612 (2004).
Article CAS PubMed Google Scholar