Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1 (original) (raw)

• Peters, J.M. The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat. Rev. Mol. Cell Biol. 7, 644–656 (2006).
  Article CAS Google Scholar
• Matyskiela, M.E., Rodrigo-Brenni, M.C. & Morgan, D.O. Mechanisms of ubiquitin transfer by the anaphase-promoting complex. J. Biol. 8, 92 (2009).
  Article Google Scholar
• Musacchio, A. & Salmon, E.D. The spindle-assembly checkpoint in space and time. Nat. Rev. Mol. Cell Biol. 8, 379–393 (2007).
  Article CAS Google Scholar
• Au, S.W., Leng, X., Harper, J.W. & Barford, D. Implications for the ubiquitination reaction of the anaphase-promoting complex from the crystal structure of the Doc1/Apc10 subunit. J. Mol. Biol. 316, 955–968 (2002).
  Article CAS Google Scholar
• Wendt, K.S. et al. Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex. Nat. Struct. Biol. 8, 784–788 (2001).
  Article CAS Google Scholar
• Wang, J., Dye, B.T., Rajashankar, K.R., Kurinov, I. & Schulman, B.A. Insights into anaphase promoting complex TPR subdomain assembly from a CDC26–APC6 structure. Nat. Struct. Mol. Biol. 16, 987–989 (2009).
  Article CAS Google Scholar
• Zhang, Z. et al. Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture. J. Mol. Biol. 397, 1316–1328 (2010).
  Article CAS Google Scholar
• Han, D., Kim, K., Kim, Y., Kang, Y. & Lee, J.Y. Crystal structure of the N-terminal domain of anaphase-promoting complex subunit 7. J. Biol. Chem. 284, 15137–15146 (2009).
  Article CAS Google Scholar
• Dube, P. et al. Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Mol. Cell 20, 867–879 (2005).
  Article CAS Google Scholar
• Herzog, F. et al. Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science 323, 1477–1481 (2009).
  Article CAS Google Scholar
• Ohi, M.D. et al. Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1. Mol. Cell 28, 871–885 (2007).
  Article CAS Google Scholar
• Passmore, L.A. et al. Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation. Mol. Cell 20, 855–866 (2005).
  Article CAS Google Scholar
• Vodermaier, H.C., Gieffers, C., Maurer-Stroh, S., Eisenhaber, F. & Peters, J.M. TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1. Curr. Biol. 13, 1459–1468 (2003).
  Article CAS Google Scholar
• Schwickart, M. et al. Swm1/Apc13 is an evolutionarily conserved subunit of the anaphase-promoting complex stabilizing the association of Cdc16 and Cdc27. Mol. Cell. Biol. 24, 3562–3576 (2004).
  Article CAS Google Scholar
• Thornton, B.R. et al. An architectural map of the anaphase-promoting complex. Genes Dev. 20, 449–460 (2006).
  Article CAS Google Scholar
• Passmore, L.A. et al. Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition. EMBO J. 22, 786–796 (2003).
  Article CAS Google Scholar
• Carroll, C.W. & Morgan, D.O. The Doc1 subunit is a processivity factor for the anaphase-promoting complex. Nat. Cell Biol. 4, 880–887 (2002).
  Article CAS Google Scholar
• Grossberger, R. et al. Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex. J. Biol. Chem. 274, 14500–14507 (1999).
  Article CAS Google Scholar
• Gieffers, C., Schleiffer, A. & Peters, J.M. Cullins and cell cycle control. Protoplasma 211, 20–28 (2000).
  Article CAS Google Scholar
• Carroll, C.W., Enquist-Newman, M. & Morgan, D.O. The APC subunit Doc1 promotes recognition of the substrate destruction box. Curr. Biol. 15, 11–18 (2005).
  Article CAS Google Scholar
• Hwang, L.H. & Murray, A.W. A novel yeast screen for mitotic arrest mutants identifies DOC1, a new gene involved in cyclin proteolysis. Mol. Biol. Cell 8, 1877–1887 (1997).
  Article CAS Google Scholar
• Brunner, J. New photolabeling and crosslinking methods. Annu. Rev. Biochem. 62, 483–514 (1993).
  Article CAS Google Scholar
• Zachariae, W., Shin, T.H., Galova, M., Obermaier, B. & Nasmyth, K. Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae. Science 274, 1201–1204 (1996).
  Article CAS Google Scholar
• Campbell, R.E. et al. A monomeric red fluorescent protein. Proc. Natl. Acad. Sci. USA 99, 7877–7882 (2002).
  Article CAS Google Scholar
• Häcker, I. et al. Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy. Nat. Struct. Mol. Biol. 15, 1206–1212 (2008).
  Article Google Scholar
• Hall, M.C., Torres, M.P., Schroeder, G.K. & Borchers, C.H. Mnd2 and Swm1 are core subunits of the Saccharomyces cerevisiae anaphase-promoting complex. J. Biol. Chem. 278, 16698–16705 (2003).
  Article CAS Google Scholar
• Yoon, H.J. et al. Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes. Curr. Biol. 12, 2048–2054 (2002).
  Article CAS Google Scholar
• Kraft, C., Vodermaier, H.C., Maurer-Stroh, S., Eisenhaber, F. & Peters, J.M. The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates. Mol. Cell 18, 543–553 (2005).
  Article CAS Google Scholar
• Matyskiela, M.E. & Morgan, D.O. Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism. Mol. Cell 34, 68–80 (2009).
  Article CAS Google Scholar
• Burton, J.L., Tsakraklides, V. & Solomon, M.J. Assembly of an APC-Cdh1-substrate complex is stimulated by engagement of a destruction box. Mol. Cell 18, 533–542 (2005).
  Article CAS Google Scholar
• Burton, J.L. & Solomon, M.J. D box and KEN box motifs in budding yeast Hsl1p are required for APC-mediated degradation and direct binding to Cdc20p and Cdh1p. Genes Dev. 15, 2381–2395 (2001).
  Article CAS Google Scholar
• Kastner, B. et al. GraFix: sample preparation for single-particle electron cryomicroscopy. Nat. Methods 5, 53–55 (2008).
  Article CAS Google Scholar
• Passmore, L.A. & Barford, D. Coactivator functions in a stoichiometric complex with anaphase-promoting complex/cyclosome to mediate substrate recognition. EMBO Rep. 6, 873–878 (2005).
  Article CAS Google Scholar
• Burton, J.L. & Solomon, M.J. Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Genes Dev. 21, 655–667 (2007).
  Article CAS Google Scholar
• Sheff, M.A. & Thorn, K.S. Optimized cassettes for fluorescent protein tagging in Saccharomyces cerevisiae. Yeast 21, 661–670 (2004).
  Article CAS Google Scholar
• Passmore, L.A., Barford, D. & Harper, J.W. Purification and assay of the budding yeast anaphase-promoting complex. Methods Enzymol. 398, 195–219 (2005).
  Article CAS Google Scholar
• Gieffers, C., Dube, P., Harris, J.R., Stark, H. & Peters, J.M. Three-dimensional structure of the anaphase-promoting complex. Mol. Cell 7, 907–913 (2001).
  Article CAS Google Scholar