Mili and Miwi target RNA repertoire reveals piRNA biogenesis and function of Miwi in spermiogenesis (original) (raw)
Cox, D.N. et al. A novel class of evolutionarily conserved genes defined by piwi are essential for stem cell self-renewal. Genes Dev.12, 3715–3727 (1998). ArticleCAS Google Scholar
Deng, W. & Lin, H. miwi, a murine homolog of piwi, encodes a cytoplasmic protein essential for spermatogenesis. Dev. Cell2, 819–830 (2002). ArticleCAS Google Scholar
Kuramochi-Miyagawa, S. et al. Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development131, 839–849 (2004). ArticleCAS Google Scholar
Boswell, R.E. & Mahowald, A.P. tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster. Cell43, 97–104 (1985). ArticleCAS Google Scholar
Chen, C., Nott, T.J., Jin, J. & Pawson, T. Deciphering arginine methylation: Tudor tells the tale. Nat. Rev. Mol. Cell Biol.12, 629–642 (2011). ArticleCAS Google Scholar
Kirino, Y. et al. Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nat. Cell Biol.11, 652–658 (2009). ArticleCAS Google Scholar
Nishida, K.M. et al. Functional involvement of Tudor and dPRMT5 in the piRNA processing pathway in Drosophila germlines. EMBO J.28, 3820–3831 (2009). ArticleCAS Google Scholar
Vagin, V.V. et al. Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev.23, 1749–1762 (2009). ArticleCAS Google Scholar
Kirino, Y. et al. Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization. RNA16, 70–78 (2010). ArticleCAS Google Scholar
Yokota, S. Historical survey on chromatoid body research. Acta Histochem. Cytochem.41, 65–82 (2008). ArticleCAS Google Scholar
Lau, N.C. et al. Characterization of the piRNA complex from rat testes. Science313, 363–367 (2006). ArticleCAS Google Scholar
Aravin, A. et al. A novel class of small RNAs bind to MILI protein in mouse testes. Nature442, 203–207 (2006). ArticleCAS Google Scholar
Girard, A., Sachidanandam, R., Hannon, G.J. & Carmell, M.A. A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature442, 199–202 (2006). Article Google Scholar
Grivna, S.T., Beyret, E., Wang, Z. & Lin, H. A novel class of small RNAs in mouse spermatogenic cells. Genes Dev.20, 1709–1714 (2006). ArticleCAS Google Scholar
Siomi, M.C., Sato, K., Pezic, D. & Aravin, A.A. PIWI-interacting small RNAs: the vanguard of genome defence. Nat. Rev. Mol. Cell Biol.12, 246–258 (2011). ArticleCAS Google Scholar
Kawaoka, S., Izumi, N., Katsuma, S. & Tomari, Y. 3′ End formation of PIWI-interacting RNAs in vitro. Mol. Cell43, 1015–1022 (2011). ArticleCAS Google Scholar
Pillai, R.S. & Chuma, S. piRNAs and their involvement in male germline development in mice. Dev. Growth Differ.54, 78–92 (2012). ArticleCAS Google Scholar
Besse, F. & Ephrussi, A. Translational control of localized mRNAs: restricting protein synthesis in space and time. Nat. Rev. Mol. Cell Biol.9, 971–980 (2008). ArticleCAS Google Scholar
Heidaran, M.A., Showman, R.M. & Kistler, W.S. A cytochemical study of the transcriptional and translational regulation of nuclear transition protein 1 (TP1), a major chromosomal protein of mammalian spermatids. J. Cell Biol.106, 1427–1433 (1988). ArticleCAS Google Scholar
Kleene, K.C. Patterns of translational regulation in the mammalian testis. Mol. Reprod. Dev.43, 268–281 (1996). ArticleCAS Google Scholar
Carmell, M.A. et al. MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev. Cell12, 503–514 (2007). ArticleCAS Google Scholar
Reuter, M. et al. Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile. Nat. Struct. Mol. Biol.16, 639–646 (2009). ArticleCAS Google Scholar
Shoji, M. et al. The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev. Cell17, 775–787 (2009). ArticleCAS Google Scholar
Kuramochi-Miyagawa, S. et al. MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev.24, 887–892 (2010). ArticleCAS Google Scholar
Frost, R.J. et al. MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs. Proc. Natl. Acad. Sci. USA107, 11847–11852 (2010). ArticleCAS Google Scholar
Zheng, K. et al. Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway. Proc. Natl. Acad. Sci. USA107, 11841–11846 (2010). ArticleCAS Google Scholar
De Fazio, S. et al. The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature480, 259–263 (2011). ArticleCAS Google Scholar
Tanaka, T. et al. Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis. Proc. Natl. Acad. Sci. USA108, 10579–10584 (2011). ArticleCAS Google Scholar
Vasileva, A., Tiedau, D., Firooznia, A., Muller-Reichert, T. & Jessberger, R. Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression. Curr. Biol.19, 630–639 (2009). ArticleCAS Google Scholar
Robine, N. et al. A broadly conserved pathway generates 3′UTR-directed primary piRNAs. Curr. Biol.19, 2066–2076 (2009). ArticleCAS Google Scholar
Gunawardane, L.S. et al. A slicer-mediated mechanism for repeat-associated siRNA 5′ end formation in Drosophila. Science315, 1587–1590 (2007). ArticleCAS Google Scholar
Horwich, M.D. et al. The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr. Biol.17, 1265–1272 (2007). ArticleCAS Google Scholar
Kirino, Y. & Mourelatos, Z. The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs. RNA13, 1397–1401 (2007). ArticleCAS Google Scholar
Simon, B. et al. Recognition of 2′-O-methylated 3′-end of piRNA by the PAZ domain of a Piwi protein. Structure19, 172–180 (2011). ArticleCAS Google Scholar
Tian, Y., Simanshu, D.K., Ma, J.B. & Patel, D.J. Structural basis for piRNA 2′-O-methylated 3′-end recognition by Piwi PAZ (Piwi/Argonaute/Zwille) domains. Proc. Natl. Acad. Sci. USA108, 903–910 (2011). ArticleCAS Google Scholar
Kirino, Y. & Mourelatos, Z. Site-specific crosslinking of human microRNPs to RNA targets. RNA14, 2254–2259 (2008). ArticleCAS Google Scholar
Reuter, M. et al. Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing. Nature480, 264–267 (2011). ArticleCAS Google Scholar
Zhang, C. & Darnell, R.B. Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data. Nat. Biotechnol.29, 607–614 (2011). ArticleCAS Google Scholar
Herbert, T.P. & Hecht, N.B. The mouse Y-box protein, MSY2, is associated with a kinase on non-polysomal mouse testicular mRNAs. Nucleic Acids Res.27, 1747–1753 (1999). ArticleCAS Google Scholar
Bagarova, J., Chowdhury, T.A., Kimura, M. & Kleene, K.C. Identification of elements in the Smcp 5′ and 3′ UTR that repress translation and promote the formation of heavy inactive mRNPs in spermatids by analysis of mutations in transgenic mice. Reproduction140, 853–864 (2010). ArticleCAS Google Scholar
Kleene, K.C., Bagarova, J., Hawthorne, S.K. & Catado, L.M. Quantitative analysis of mRNA translation in mammalian spermatogenic cells with sucrose and Nycodenz gradients. Reproductive biology and endocrinology8, 155 (2010). ArticleCAS Google Scholar
Giorgini, F., Davies, H.G. & Braun, R.E. Translational repression by MSY4 inhibits spermatid differentiation in mice. Development129, 3669–3679 (2002). CASPubMed Google Scholar
Kimura, M., Ishida, K., Kashiwabara, S. & Baba, T. Characterization of two cytoplasmic poly(A)-binding proteins, PABPC1 and PABPC2, in mouse spermatogenic cells. Biol. Reprod.80, 545–554 (2009). ArticleCAS Google Scholar
Yang, J., Medvedev, S., Reddi, P.P., Schultz, R.M. & Hecht, N.B. The DNA/RNA-binding protein MSY2 marks specific transcripts for cytoplasmic storage in mouse male germ cells. Proc. Natl. Acad. Sci. USA102, 1513–1518 (2005). ArticleCAS Google Scholar
Yang, J. et al. Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility. Proc. Natl. Acad. Sci. USA102, 5755–5760 (2005). ArticleCAS Google Scholar
Huang, H. et al. piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling. Dev. Cell20, 376–387 (2011). ArticleCAS Google Scholar
Watanabe, T. et al. MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev. Cell20, 364–375 (2011). ArticleCAS Google Scholar
Hermo, L., Pelletier, R.M., Cyr, D.G. & Smith, C.E. Surfing the wave, cycle, life history, and genes/proteins expressed by testicular germ cells. Part 2: changes in spermatid organelles associated with development of spermatozoa. Microsc. Res. Tech.73, 279–319 (2010). ArticleCAS Google Scholar
Haraguchi, C.M. et al. Chromatoid bodies: aggresome-like characteristics and degradation sites for organelles of spermiogenic cells. J. Histochem. Cytochem.53, 455–465 (2005). ArticleCAS Google Scholar
Austin, C.R. & Sapsford, C.S. The development of the rat spermatid. J. R. Microsc. Soc.71, 397–406 (1951). ArticleCAS Google Scholar
Dostie, J. & Dreyfuss, G. Translation is required to remove Y14 from mRNAs in the cytoplasm. Curr. Biol.12, 1060–1067 (2002). ArticleCAS Google Scholar
Faehnle, C.R. & Joshua-Tor, L. Argonaute MID domain takes centre stage. EMBO Rep.11, 564–565 (2010). ArticleCAS Google Scholar
Liu, X., Jin, D.Y., McManus, M.T. & Mourelatos, Z. Precursor microRNA-programmed silencing complex assembly pathways in mammals. Mol. Cell46, 507–517 (2012). ArticleCAS Google Scholar
Oko, R.J., Jando, V., Wagner, C.L., Kistler, W.S. & Hermo, L.S. Chromatin reorganization in rat spermatids during the disappearance of testis-specific histone, H1t, and the appearance of transition proteins TP1 and TP2. Biol. Reprod.54, 1141–1157 (1996). ArticleCAS Google Scholar
Alfonso, P.J. & Kistler, W.S. Immunohistochemical localization of spermatid nuclear transition protein 2 in the testes of rats and mice. Biol. Reprod.48, 522–529 (1993). ArticleCAS Google Scholar